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PDB: 723 件

1EXZ
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STRUCTURE OF STEM CELL FACTOR
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, SAMARIUM (III) ION, ...
著者Zhang, Z, Zhang, R, Joachimiak, A, Schlessinger, J, Kong, X.
登録日2000-05-05
公開日2000-07-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of human stem cell factor: implication for stem cell factor receptor dimerization and activation.
Proc.Natl.Acad.Sci.USA, 97, 2000
4GE2
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Crystal structure of human protein tyrosine phosphatase PTPN9 (MEG2) complex with compound 3
分子名称: N-acetyl-4-[difluoro(phosphono)methyl]-L-phenylalanyl-N~5~-(3-iodobenzoyl)-L-ornithinamide, Tyrosine-protein phosphatase non-receptor type 9
著者Zhang, Z.-Y, Liu, S, Zhang, S.
登録日2012-08-01
公開日2012-10-31
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A Highly Selective and Potent PTP-MEG2 Inhibitor with Therapeutic Potential for Type 2 Diabetes.
J.Am.Chem.Soc., 134, 2012
4GE5
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Crystal structure of human protein tyrosine phosphatase PTPN9 (MEG2) complex with compound 5
分子名称: N-(4-bromo-3-methylbenzoyl)-4-[difluoro(phosphono)methyl]-L-phenylalanyl-N~5~-(3-iodobenzoyl)-L-ornithinamide, Tyrosine-protein phosphatase non-receptor type 9
著者Zhang, Z.-Y, Liu, S, Zhang, S.
登録日2012-08-01
公開日2012-10-31
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A Highly Selective and Potent PTP-MEG2 Inhibitor with Therapeutic Potential for Type 2 Diabetes.
J.Am.Chem.Soc., 134, 2012
3D8X
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BU of 3d8x by Molmil
Crystal Structure of Saccharomyces cerevisiae NDPPH Dependent Thioredoxin Reductase 1
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Thioredoxin reductase 1
著者Zhang, Z.Y, Bao, R, Yu, J, Chen, Y.X, Zhou, C.-Z.
登録日2008-05-26
公開日2008-12-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of Saccharomyces cerevisiae cytoplasmic thioredoxin reductase Trr1 reveals the structural basis for species-specific recognition of thioredoxin
Biochim.Biophys.Acta, 1794, 2009
1WA6
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The structure of ACC oxidase
分子名称: 1-AMINOCYCLOPROPANE-1-CARBOXYLATE OXIDASE 1, FE (II) ION, PHOSPHATE ION, ...
著者Zhang, Z, Ren, J.-S, Clifton, I.J, Schofield, C.J.
登録日2004-10-25
公開日2005-10-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal Structure and Mechanistic Implications of 1-Aminocyclopropane-1-Carboxylic Acid Oxidase (the Ethyling Forming Enzyme)
Chem.Biol., 11, 2004
3VAX
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BU of 3vax by Molmil
Crystal structure of DndA from streptomyces lividans
分子名称: PYRIDOXAL-5'-PHOSPHATE, Putative uncharacterized protein dndA
著者Zhang, Z, Chen, F, Lin, K, Wu, G.
登録日2011-12-30
公開日2013-01-02
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the cysteine desulfurase DndA from Streptomyces lividans which is involved in DNA phosphorothioation
Plos One, 7, 2012
7DEU
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Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody scFv
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody scFv
著者Zhang, Z, Zhang, G, Li, X, Rao, Z, Guo, Y.
登録日2020-11-05
公開日2021-03-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for SARS-CoV-2 neutralizing antibodies with novel binding epitopes.
Plos Biol., 19, 2021
3MOW
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Crystal structure of SHP2 in complex with a tautomycetin analog TTN D-1
分子名称: (2Z)-2-[(1R)-3-{[(1R,2S,3R,6S,7S,10S,12S,15E,17E)-18-carboxy-16-ethyl-3,7-dihydroxy-1,2,6,10,12-pentamethyl-5-oxooctade ca-15,17-dien-1-yl]oxy}-1-hydroxy-3-oxopropyl]-3-methylbut-2-enedioic acid, Tyrosine-protein phosphatase non-receptor type 11
著者Zhang, Z.-Y, Liu, S, Yu, Z, Yu, X.
登録日2010-04-23
公開日2011-05-04
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of SHP2 in complex with a tautomycetin analog TTN D-1
To be Published
3DA8
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Crystal structure of PurN from Mycobacterium tuberculosis
分子名称: BETA-MERCAPTOETHANOL, IODIDE ION, MAGNESIUM ION, ...
著者Zhang, Z, Squire, C.J, Baker, E.N.
登録日2008-05-28
公開日2009-05-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structures of glycinamide ribonucleotide transformylase (PurN) from Mycobacterium tuberculosis reveal a novel dimer with relevance to drug discovery.
J.Mol.Biol., 389, 2009
3DCJ
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BU of 3dcj by Molmil
Crystal structure of glycinamide formyltransferase (PurN) from Mycobacterium tuberculosis in complex with 5-methyl-5,6,7,8-tetrahydrofolic acid derivative
分子名称: CHLORIDE ION, MAGNESIUM ION, N-[4-({[(6S)-2-AMINO-4-HYDROXY-5-METHYL-5,6,7,8-TETRAHYDROPTERIDIN-6-YL]METHYL}AMINO)BENZOYL]-L-GLUTAMIC ACID, ...
著者Zhang, Z, Squire, C.J, Baker, E.N.
登録日2008-06-03
公開日2009-05-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structures of glycinamide ribonucleotide transformylase (PurN) from Mycobacterium tuberculosis reveal a novel dimer with relevance to drug discovery.
J.Mol.Biol., 389, 2009
5W40
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Crystal structure of PopP2 F318S in complex with IP6 and AcCoA
分子名称: COENZYME A, INOSITOL HEXAKISPHOSPHATE, PopP2 protein
著者Zhang, Z.M, Gao, L, Song, J.
登録日2017-06-08
公開日2017-08-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Mechanism of host substrate acetylation by a YopJ family effector.
Nat Plants, 3, 2017
5W3Y
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Crystal structure of PopP2 C321A in complex with IP6 and AcCoA
分子名称: ACETYL COENZYME *A, INOSITOL HEXAKISPHOSPHATE, PopP2 protein
著者Zhang, Z.M, Gao, L, Song, J.
登録日2017-06-08
公開日2017-08-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Mechanism of host substrate acetylation by a YopJ family effector.
Nat Plants, 3, 2017
3VA9
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Crystal structure of the Rhodopseudomonas palustris histidine kinase HK9 sensor domain
分子名称: CHLORIDE ION, Sensor histidine kinase
著者Zhang, Z, Liu, Q, Hendrickson, W.A.
登録日2011-12-29
公開日2012-06-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the Rhodopseudomonas palustris histidine kinase HK9 sensor domain
To be Published
3M2T
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BU of 3m2t by Molmil
The crystal structure of dehydrogenase from Chromobacterium violaceum
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Probable dehydrogenase, SULFATE ION
著者Zhang, Z, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2010-03-08
公開日2010-04-07
最終更新日2021-10-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The crystal structure of dehydrogenase from Chromobacterium violaceum
To be Published
3VA6
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Crystal Structure of the extracellular domain of the putative hybrid two component system BT4673 from B. thetaiotaomicron
分子名称: Two-component system sensor histidine kinase
著者Zhang, Z, Liu, Q, Hendrickson, W.A.
登録日2011-12-28
公開日2012-06-13
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Extraellular Domain Structures of Two Potential Saccharide-sensing Two-component Systems from a Human Gut Symbiont
To be Published
3LL3
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BU of 3ll3 by Molmil
The crystal structure of ligand bound xylulose kinase from Lactobacillus acidophilus
分子名称: 1-DEOXY-D-XYLULOSE-5-PHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Zhang, Z, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2010-01-28
公開日2010-03-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.002 Å)
主引用文献The crystal structure of xylulose kinase from Lactobacillus acidophilus
To be Published
3LWI
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BU of 3lwi by Molmil
Crystal structure of Cren7-dsDNA complex
分子名称: Chromatin protein Cren7, DNA (5'-D(*GP*CP*GP*AP*TP*CP*GP*C)-3')
著者Zhang, Z.F, Gong, Y, Guo, L, Jiang, T, Huang, L.
登録日2010-02-23
公開日2010-05-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural insights into the interaction of the crenarchaeal chromatin protein Cren7 with DNA
Mol.Microbiol., 76, 2010
3LWH
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Crystal structure of Cren7-dsDNA complex
分子名称: Chromatin protein Cren7, DNA (5'-D(*GP*TP*AP*AP*TP*TP*AP*C)-3')
著者Zhang, Z.F, Gong, Y, Guo, L, Jiang, T, Huang, L.
登録日2010-02-23
公開日2010-05-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insights into the interaction of the crenarchaeal chromatin protein Cren7 with DNA
Mol.Microbiol., 76, 2010
5W81
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Phosphorylated, ATP-bound structure of zebrafish cystic fibrosis transmembrane conductance regulator (CFTR)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION
著者Zhang, Z, Liu, F, Chen, J.
登録日2017-06-21
公開日2017-07-19
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Conformational Changes of CFTR upon Phosphorylation and ATP Binding.
Cell, 170, 2017
6LR7
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BU of 6lr7 by Molmil
Crystal structure of GFPuv complexed with the nanobody LaG16 at 1.67 Angstron resolution
分子名称: Green fluorescent protein, Nanobody LaG16
著者Zhang, Z.Y, Ding, Y, Hattori, M.
登録日2020-01-15
公開日2020-04-29
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Structure-based engineering of anti-GFP nanobody tandems as ultra-high-affinity reagents for purification.
Sci Rep, 10, 2020
7RY3
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Multidrug Efflux pump AdeJ with TP-6076 bound
分子名称: (4S,4aS,5aR,12aS)-4-(diethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-8-[(2S)-pyrrolidin-2-yl]-7-(trifluoromethyl)-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, Efflux pump membrane transporter
著者Zhang, Z.
登録日2021-08-24
公開日2022-02-02
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.91 Å)
主引用文献An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii.
Mbio, 13, 2022
8IDE
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BU of 8ide by Molmil
Structure of an ancient TsaD-TsaC-SUA5-TcdA modular enzyme (TsaN)
分子名称: MANGANESE (II) ION, N(6)-L-threonylcarbamoyladenine synthase
著者Zhang, Z.L, Jin, M.Q, Yu, Z.J, Chen, W, Wang, X.L, Lei, D.S, Zhang, W.H.
登録日2023-02-13
公開日2023-07-26
最終更新日2023-09-20
実験手法ELECTRON MICROSCOPY (3.21 Å)
主引用文献Structure-function analysis of an ancient TsaD-TsaC-SUA5-TcdA modular enzyme reveals a prototype of tRNA t6A and ct6A synthetases.
Nucleic Acids Res., 51, 2023
6LVY
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Crystal structure of TLR7/Cpd-2 (SM-360320) complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6-azanyl-2-(2-methoxyethoxy)-9-(phenylmethyl)-7H-purin-8-one, ...
著者Zhang, Z, Ohto, U, Shimizu, T.
登録日2020-02-06
公開日2020-11-11
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural analysis reveals TLR7 dynamics underlying antagonism.
Nat Commun, 11, 2020
6LW0
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Crystal structure of TLR7/Cpd-6 (DSR-139293) complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-ethoxy-8-(5-fluoranylpyridin-3-yl)-9-[[4-[[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]methyl]phenyl]methyl]purin-6-amine, ...
著者Zhang, Z, Ohto, U, Shimizu, T.
登録日2020-02-06
公開日2020-11-11
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural analysis reveals TLR7 dynamics underlying antagonism.
Nat Commun, 11, 2020
6Y6I
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lipopolysaccharide outer core galactosyltransferase WaaB and UDP complex
分子名称: Lipopolysaccharide 1,6-galactosyltransferase, URIDINE-5'-DIPHOSPHATE
著者Zhang, Z.Y, Ashworth, G, Wang, Z.S, Zhu, X.F, Dong, C.J.
登録日2020-02-26
公開日2021-03-31
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Structural insights into the lipopolysaccharide outer core galactosyltransferase WaaB
To Be Published

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件を2024-07-17に公開中

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