6HOK
| Structure of Beclin1 LIR (S96E) motif bound to GABARAP | 分子名称: | 1,2-ETHANEDIOL, Beclin-1,Gamma-aminobutyric acid receptor-associated protein | 著者 | Mouilleron, S, Birgisdottir, A.B, Bhujbal, Z, Wirth, M, Sjottem, E, Evjen, G, Zhang, W, Lee, R, O'Reilly, N, Tooze, S, Lamark, T, Johansen, T. | 登録日 | 2018-09-17 | 公開日 | 2019-02-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs. Autophagy, 15, 2019
|
|
6HOG
| Structure of VPS34 LIR motif bound to GABARAP | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Phosphatidylinositol 3-kinase catalytic subunit type 3,Gamma-aminobutyric acid receptor-associated protein, ... | 著者 | Mouilleron, S, Birgisdottir, A.B, Bhujbal, Z, Wirth, M, Sjottem, E, Evjen, G, Zhang, W, Lee, R, O'Reilly, N, Tooze, S, Lamark, T, Johansen, T. | 登録日 | 2018-09-17 | 公開日 | 2019-02-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | 主引用文献 | Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs. Autophagy, 15, 2019
|
|
6HYN
| Structure of ATG13 LIR motif bound to GABARAP | 分子名称: | Autophagy-related protein 13,Gamma-aminobutyric acid receptor-associated protein | 著者 | Mouilleron, S, Wirth, M, Zhang, W, O'Reilly, N, Tooze, S, Johansen, T, Razi, M, Nyoni, L, Joshi, D. | 登録日 | 2018-10-22 | 公開日 | 2019-05-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.14 Å) | 主引用文献 | Molecular determinants regulating selective binding of autophagy adapters and receptors to ATG8 proteins. Nat Commun, 10, 2019
|
|
8OR1
| Co-crystal strucutre of PD-L1 with low molecular weight inhibitor | 分子名称: | 5-[[5-[[2-chloranyl-3-(2-fluorophenyl)phenyl]methoxy]-2-[(~{E})-2-hydroxyethyliminomethyl]phenoxy]methyl]pyridine-3-carbonitrile, Programmed cell death 1 ligand 1 | 著者 | Zhang, H, Zhou, S, Wu, C, Zhu, M, Yu, Q, Wang, X, Awadasseid, A, Plewka, J, Magiera-Mularz, K, Wu, Y, Zhang, W. | 登録日 | 2023-04-12 | 公開日 | 2023-08-02 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Design, Synthesis, and Antitumor Activity Evaluation of 2-Arylmethoxy-4-(2,2'-dihalogen-substituted biphenyl-3-ylmethoxy) Benzylamine Derivatives as Potent PD-1/PD-L1 Inhibitors. J.Med.Chem., 66, 2023
|
|
7WA9
| |
8IQU
| Structure of MtbFadD23 with PhU-AMS | 分子名称: | 5'-O-[(11-phenoxyundecanoyl)sulfamoyl]adenosine, Fatty-acid-CoA ligase FadD23 | 著者 | Yan, M.R, Zhang, W. | 登録日 | 2023-03-17 | 公開日 | 2023-04-26 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | Structural basis for the development of potential inhibitors targeting FadD23 from Mycobacterium tuberculosis. Acta Crystallogr.,Sect.F, 79, 2023
|
|
8K20
| Cryo-EM structure of KEOPS complex from Arabidopsis thaliana | 分子名称: | At4g34412, At5g53043, FE (III) ION, ... | 著者 | Zheng, X.X, Zhu, L, Duan, L, Zhang, W.H. | 登録日 | 2023-07-11 | 公開日 | 2024-04-03 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Molecular basis of A. thaliana KEOPS complex in biosynthesizing tRNA t6A. Nucleic Acids Res., 52, 2024
|
|
7N7X
| Crystal structure of BCX7353(ORLADEYO) in complex with human plasma kallikrein serine protease domain at 2.1 angstrom resolution | 分子名称: | Orladeyo, PHOSPHATE ION, Plasma kallikrein light chain | 著者 | Krishnan, R, Yarlagadda, B.S, Kotian, P, Polach, K.J, Zhang, W. | 登録日 | 2021-06-11 | 公開日 | 2021-09-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.097 Å) | 主引用文献 | Berotralstat (BCX7353): Structure-Guided Design of a Potent, Selective, and Oral Plasma Kallikrein Inhibitor to Prevent Attacks of Hereditary Angioedema (HAE). J.Med.Chem., 64, 2021
|
|
7M3Q
| Structure of the Smurf2 HECT Domain with a High Affinity Ubiquitin Variant (UbV) | 分子名称: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CHLORIDE ION, ... | 著者 | Chowdhury, A, Singer, A.U, Ogunjimi, A.A, Teyra, J, Zhang, W, Sicheri, F, Sidhu, S.S. | 登録日 | 2021-03-18 | 公開日 | 2021-04-21 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of the Smurf2 HECT Domain with a High Affinity Ubiquitin Variant (UbV) To be published
|
|
7ESH
| Crystal structure of amylosucrase from Calidithermus timidus | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, amylosucrase | 著者 | Tian, Y, Hou, X, Ni, D, Xu, W, Guang, C, Zhang, W, Rao, Y, Mu, W. | 登録日 | 2021-05-10 | 公開日 | 2022-05-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Structure-based interface engineering methodology in designing a thermostable amylose-forming transglucosylase J.Biol.Chem., 298, 2022
|
|
7VUL
| |
2HD3
| Crystal Structure of the Ethanolamine Utilization Protein EutN from Escherichia coli, NESG Target ER316 | 分子名称: | Ethanolamine utilization protein eutN | 著者 | Forouhar, F, Zhang, W, Jayaraman, S, Zhao, L, Jiang, M, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2006-06-19 | 公開日 | 2006-08-15 | 最終更新日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Functional insights from structural genomics. J.STRUCT.FUNCT.GENOM., 8, 2007
|
|
8IEY
| Aquifex aeolicus TsaD-TsaB | 分子名称: | DI(HYDROXYETHYL)ETHER, FE (III) ION, Gcp-like domain-containing protein, ... | 著者 | Lu, S.Z, Zhang, W.H. | 登録日 | 2023-02-16 | 公開日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of Aquifex aeolicus TsaD-TsaB complex To Be Published
|
|
8IFX
| |
8JJM
| |
7E6T
| Structural insights into the activation of human calcium-sensing receptor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CYCLOMETHYLTRYPTOPHAN, ... | 著者 | Geng, Y, Chen, X.C, Wang, L, Cui, Q.Q, Ding, Z.Y, Han, L, Kou, Y.J, Zhang, W.Q, Wang, H.N, Jia, X.M, Dai, M, Shi, Z.Z, Li, Y.Y, Li, X.Y. | 登録日 | 2021-02-24 | 公開日 | 2021-09-22 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural insights into the activation of human calcium-sensing receptor. Elife, 10, 2021
|
|
7E6U
| the complex of inactive CaSR and NB2D11 | 分子名称: | Extracellular calcium-sensing receptor, NB-2D11 | 著者 | Geng, Y, Chen, X.C, Wang, L, Cui, Q.Q, Ding, Z.Y, Han, L, Kou, Y.J, Zhang, W.Q, Wang, H.N, Jia, X.M, Dai, M, Shi, Z.Z, Li, Y.Y, Li, X.Y. | 登録日 | 2021-02-24 | 公開日 | 2021-09-22 | 実験手法 | ELECTRON MICROSCOPY (6 Å) | 主引用文献 | Structural insights into the activation of human calcium-sensing receptor. Elife, 10, 2021
|
|
7DEB
| Structure of an avian influenza H5 hemagglutinin from the influenza virus A/duck/Eastern China/L0230/2010 (H5N2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | 著者 | Sun, H, Sun, H, Song, J, Zhang, W, Qi, J, Gao, G.F, Liu, J. | 登録日 | 2020-11-03 | 公開日 | 2021-11-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Haemagglutinin and neuraminidase acid stability in H5N6 avian influenza virus confers infection adaptation in mammals To Be Published
|
|
7C0N
| Crystal structure of a self-assembling galactosylated peptide homodimer | 分子名称: | SULFATE ION, Self-assembling galactosylated tyrosine-rich peptide, beta-D-galactopyranose | 著者 | He, C, Wu, S, Chi, C, Zhang, W, Ma, M, Lai, L, Dong, S. | 登録日 | 2020-05-01 | 公開日 | 2020-10-07 | 最終更新日 | 2020-10-21 | 実験手法 | X-RAY DIFFRACTION (1.552 Å) | 主引用文献 | Glycopeptide Self-Assembly Modulated by Glycan Stereochemistry through Glycan-Aromatic Interactions. J.Am.Chem.Soc., 142, 2020
|
|
7DEA
| Structure of an avian influenza H5 hemagglutinin from the influenza virus A/duck Northern China/22/2017 (H5N6) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin | 著者 | Sun, H, Sun, H, Song, J, Zhang, W, Wei, X, Qi, J, Gao, G.F, Liu, J. | 登録日 | 2020-11-03 | 公開日 | 2021-11-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | 主引用文献 | Haemagglutinin and neuraminidase acid stability in H5N6 avian influenza virus confers infection adaptation in mammals To Be Published
|
|
7XCA
| Crystal structure of the porcine astrovirus capsid spike domain | 分子名称: | CHLORIDE ION, Capsid protein spike domain, MAGNESIUM ION | 著者 | Pan, L.X, Zhang, W.C, Yang, D.F, Yang, L.Y, Liu, H. | 登録日 | 2022-03-23 | 公開日 | 2023-03-29 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure analysis of porcine astrovirus capsid spike and spike/neutralizing antibody complexes. To Be Published
|
|
8W6K
| in situ room temperature Laue crystallography | 分子名称: | Lysozyme C | 著者 | Wang, Z.J, Wang, S.S, Pan, Q.Y, Yu, L, Su, Z.H, Yang, T.Y, Wang, Y.Z, Zhang, W.Z, Hao, Q, Gao, X.Y. | 登録日 | 2023-08-29 | 公開日 | 2024-01-17 | 最終更新日 | 2024-10-02 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | BL03HB: a Laue microdiffraction beamline for both protein crystallography and materials science at SSRF Nucl.Sci.Tech., 35, 2024
|
|
3TL1
| Crystal structure of the Streptomyces coelicolor WhiE ORFVI polyketide aromatase/cyclase | 分子名称: | 6,7,9-trihydroxy-3-methyl-1H-benzo[g]isochromen-1-one, GLYCEROL, Polyketide cyclase | 著者 | Lee, M.-Y, Ames, B.D, Zhang, W, Tang, Y, Tsai, S.-C. | 登録日 | 2011-08-29 | 公開日 | 2012-04-04 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Insight into the Molecular Basis of Aromatic Polyketide Cyclization: Crystal Structure and in Vitro Characterization of WhiE-ORFVI. Biochemistry, 51, 2012
|
|