3G60
 
 | | Structure of P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding | | Descriptor: | (4R,11R,18R)-4,11,18-tri(propan-2-yl)-6,13,20-triselena-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1~5,8~.1~12,15~]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, Multidrug resistance protein 1a | | Authors: | Aller, S.G, Yu, J, Ward, A, Weng, Y, Chittaboina, S, Zhuo, R, Harrell, P.M, Trinh, Y.T, Zhang, Q, Urbatsch, I.L, Chang, G. | | Deposit date: | 2009-02-05 | | Release date: | 2009-03-24 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (4.4 Å) | | Cite: | Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding.
Science, 323, 2009
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3IXV
 | | Scorpion Hemocyanin resting state pseudo atomic model built based on cryo-EM density map | | Descriptor: | Hemocyanin AA6 chain | | Authors: | Cong, Y, Zhang, Q, Woolford, D, Schweikardt, T, Khant, H, Ludtke, S, Chiu, W, Decker, H. | | Deposit date: | 2009-02-13 | | Release date: | 2009-06-02 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (6.8 Å) | | Cite: | Structural Mechanism of SDS-Induced Enzyme Activity of Scorpion Hemocyanin Revealed by Electron Cryomicroscopy.
Structure, 17, 2009
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3IXW
 | | Scorpion Hemocyanin activated state pseudo atomic model built based on cryo-EM density map | | Descriptor: | Hemocyanin AA6 chain | | Authors: | Cong, Y, Zhang, Q, Woolford, D, Schweikardt, T, Khant, H, Ludtke, S, Chiu, W, Decker, H. | | Deposit date: | 2009-02-13 | | Release date: | 2009-06-02 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (8 Å) | | Cite: | Structural Mechanism of SDS-Induced Enzyme Activity of Scorpion Hemocyanin Revealed by Electron Cryomicroscopy.
Structure, 17, 2009
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3J40
 | | Validated Near-Atomic Resolution Structure of Bacteriophage Epsilon15 Derived from Cryo-EM and Modeling | | Descriptor: | gp10, gp7 | | Authors: | Baker, M.L, Hryc, C.F, Zhang, Q, Wu, W, Jakana, J, Haase-Pettingell, C, Afonine, P.V, Adams, P.D, King, J.A, Jiang, W, Chiu, W. | | Deposit date: | 2013-05-30 | | Release date: | 2013-07-10 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Validated near-atomic resolution structure of bacteriophage epsilon15 derived from cryo-EM and modeling.
Proc.Natl.Acad.Sci.USA, 110, 2013
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3JBM
 | | Electron cryo-microscopy of a virus-like particle of orange-spotted grouper nervous necrosis virus | | Descriptor: | virus-like particle of orange-spotted grouper nervous necrosis virus | | Authors: | Xie, J, Li, K, Gao, Y, Huang, R, Lai, Y, Shi, Y, Yang, S, Zhu, G, Zhang, Q, He, J. | | Deposit date: | 2015-09-06 | | Release date: | 2016-10-19 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structural analysis and insertion study reveal the ideal sites for surface displaying foreign peptides on a betanodavirus-like particle
Vet. Res., 47, 2016
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3K9V
 | | Crystal structure of rat mitochondrial P450 24A1 S57D in complex with CHAPS | | Descriptor: | 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, ... | | Authors: | Annalora, A.J, Goodin, D.B, Hong, W, Zhang, Q, Johnson, E.F, Stout, C.D. | | Deposit date: | 2009-10-16 | | Release date: | 2009-12-15 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of CYP24A1, a mitochondrial cytochrome P450 involved in vitamin D metabolism.
J.Mol.Biol., 396, 2010
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3K9Y
 | | Crystal structure of rat mitochondrial P450 24A1 S57D in complex with CYMAL-5 | | Descriptor: | 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, ... | | Authors: | Annalora, A.J, Goodin, D.B, Hong, W, Zhang, Q, Johnson, E.F, Stout, C.D. | | Deposit date: | 2009-10-16 | | Release date: | 2009-12-15 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of CYP24A1, a mitochondrial cytochrome P450 involved in vitamin D metabolism.
J.Mol.Biol., 396, 2010
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3JA9
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3JAA
 | | HUMAN DNA POLYMERASE ETA in COMPLEX WITH NORMAL DNA AND INCO NUCLEOTIDE (NRM) | | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*T*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3, DNA (5'-D(*TP*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... | | Authors: | Lau, W.C.Y, Li, Y, Zhang, Q, Huen, M.S.Y. | | Deposit date: | 2015-05-19 | | Release date: | 2015-12-23 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (22 Å) | | Cite: | Molecular architecture of the Ub-PCNA/Pol eta complex bound to DNA
Sci Rep, 5, 2015
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6INB
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6INC
 | | Crystal structure of an acetolactate decarboxylase from Klebsiella pneumoniae | | Descriptor: | 1,2-ETHANEDIOL, Alpha-acetolactate decarboxylase, CHLORIDE ION, ... | | Authors: | Wu, W, Zhang, Q, Bartlam, M. | | Deposit date: | 2018-10-24 | | Release date: | 2019-01-16 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.604 Å) | | Cite: | Structural characterization of an acetolactate decarboxylase from Klebsiella pneumoniae
Biochem. Biophys. Res. Commun., 509, 2019
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6JC4
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6BL6
 | | Crystallization of lipid A transporter MsbA from Salmonella typhimurium | | Descriptor: | Lipid A export ATP-binding/permease protein MsbA | | Authors: | Padayatti, P.S, Stanfield, R.L, Zhang, Q, Wilson, I.A, Lee, S.C. | | Deposit date: | 2017-11-09 | | Release date: | 2019-01-09 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural Insights into the Lipid A Transport Pathway in MsbA.
Structure, 27, 2019
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6BNH
 | | Solution NMR structures of BRD4 ET domain with JMJD6 peptide | | Descriptor: | Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, Bromodomain-containing protein 4 | | Authors: | Konuma, T, Yu, D, Zhao, C, Ju, Y, Sharma, R, Ren, C, Zhang, Q, Zhou, M.-M, Zeng, L. | | Deposit date: | 2017-11-16 | | Release date: | 2017-12-20 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural Mechanism of the Oxygenase JMJD6 Recognition by the Extraterminal (ET) Domain of BRD4.
Sci Rep, 7, 2017
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6DNY
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4HYX
 | | Crystal Structure Analysis of the Bacteriorhodopsin in Facial Amphiphile-4 DMPC Bicelle | | Descriptor: | Bacteriorhodopsin, DECANE, GLYCEROL, ... | | Authors: | Lee, S, Stout, C.D, Zhang, Q. | | Deposit date: | 2012-11-14 | | Release date: | 2013-03-20 | | Last modified: | 2013-05-22 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Steroid-based facial amphiphiles for stabilization and crystallization of membrane proteins.
Proc.Natl.Acad.Sci.USA, 110, 2013
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3QPS
 | | Crystal structures of CmeR-bile acid complexes from Campylobacter jejuni | | Descriptor: | CHOLIC ACID, CmeR | | Authors: | Lei, H.T, Routh, M.D, Shen, Z, Su, C.C, Zhang, Q, Yu, E.W. | | Deposit date: | 2011-02-14 | | Release date: | 2011-03-09 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.351 Å) | | Cite: | Crystal structures of CmeR-bile acid complexes from Campylobacter jejuni.
Protein Sci., 20, 2011
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3QQA
 | | Crystal structures of CmeR-bile acid complexes from Campylobacter jejuni | | Descriptor: | CmeR, TAUROCHOLIC ACID | | Authors: | Lei, H.T, Routh, M.D, Shen, Z, Su, C.-C, Zhang, Q, Yu, E.W. | | Deposit date: | 2011-02-15 | | Release date: | 2011-03-16 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structures of CmeR-bile acid complexes from Campylobacter jejuni.
Protein Sci., 20, 2011
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6LN1
 | | A natural inhibitor of DYRK1A for treatment of diabetes mellitus | | Descriptor: | 1,3,5,8-tetrakis(oxidanyl)xanthen-9-one, Dual specificity tyrosine-phosphorylation-regulated kinase 1A | | Authors: | Li, H, Chen, L.X, Zheng, M.Z, Zhang, Q.Z, Zhang, C.L, Wu, C.R, Yang, K.Y, Song, Z.R, Wang, Q.Q, Li, C, Zhou, Y.R, Chen, J.C. | | Deposit date: | 2019-12-28 | | Release date: | 2021-10-06 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.699 Å) | | Cite: | A natural DYRK1A inhibitor as a potential stimulator for beta-cell proliferation in diabetes.
Clin Transl Med, 11, 2021
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6JYV
 | | Structure of an isopenicillin N synthase from Pseudomonas aeruginosa PAO1 | | Descriptor: | Probable iron/ascorbate oxidoreductase, SODIUM ION | | Authors: | Hao, Z, Che, S, Wang, R, Liu, R, Zhang, Q, Bartlam, M. | | Deposit date: | 2019-04-28 | | Release date: | 2019-05-22 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.651 Å) | | Cite: | Structural characterization of an isopenicillin N synthase family oxygenase from Pseudomonas aeruginosa PAO1.
Biochem.Biophys.Res.Commun., 514, 2019
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4F4C
 | | The Crystal Structure of the Multi-Drug Transporter | | Descriptor: | Multidrug resistance protein pgp-1, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, undecyl 4-O-alpha-D-glucopyranosyl-1-thio-beta-D-glucopyranoside | | Authors: | Jin, M.S, Oldham, M.L, Zhang, Q, Chen, J. | | Deposit date: | 2012-05-10 | | Release date: | 2012-09-26 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Crystal structure of the multidrug transporter P-glycoprotein from Caenorhabditis elegans.
Nature, 490, 2012
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4HWL
 | | Crystal Structure Analysis of the Bacteriorhodopsin in Facial Amphiphile-7 DMPC Bicelle | | Descriptor: | Bacteriorhodopsin, GLYCEROL, HEPTANE, ... | | Authors: | Lee, S, Stout, C.D, Zhang, Q. | | Deposit date: | 2012-11-08 | | Release date: | 2013-03-20 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Steroid-based facial amphiphiles for stabilization and crystallization of membrane proteins.
Proc.Natl.Acad.Sci.USA, 110, 2013
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6RFL
 | | Structure of the complete Vaccinia DNA-dependent RNA polymerase complex | | Descriptor: | DNA-dependent RNA polymerase subunit rpo132, DNA-dependent RNA polymerase subunit rpo147, DNA-dependent RNA polymerase subunit rpo18, ... | | Authors: | Grimm, C, Hillen, S.H, Bedenk, K, Bartuli, J, Neyer, S, Zhang, Q, Huettenhofer, A, Erlacher, M, Dienemann, C, Schlosser, A, Urlaub, H, Boettcher, B, Szalay, A.A, Cramer, P, Fischer, U. | | Deposit date: | 2019-04-15 | | Release date: | 2019-12-11 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (2.76 Å) | | Cite: | Structural Basis of Poxvirus Transcription: Vaccinia RNA Polymerase Complexes.
Cell, 179, 2019
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4QN1
 | | Crystal Structure of a Functionally Uncharacterized Domain of E3 Ubiquitin Ligase SHPRH | | Descriptor: | E3 ubiquitin-protein ligase SHPRH, SULFATE ION, UNKNOWN ATOM OR ION, ... | | Authors: | Dong, A, Zhang, Q, Li, Y, Walker, J.R, Guan, X, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | | Deposit date: | 2014-06-17 | | Release date: | 2014-08-13 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.48 Å) | | Cite: | Crystal structure of a Function Uncharacterized Domain of E3 Ubiquitin Ligase SHPRH
To be Published
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8Y8K
 | | The structure of hAE3 | | Descriptor: | Anion exchange protein 3 | | Authors: | Jian, L, Zhang, Q, Yao, D, Wang, Q, Xia, Y, Qin, A, Cao, Y. | | Deposit date: | 2024-02-06 | | Release date: | 2024-07-31 | | Last modified: | 2024-08-07 | | Method: | ELECTRON MICROSCOPY (2.89 Å) | | Cite: | The structural insight into the functional modulation of human anion exchanger 3.
Nat Commun, 15, 2024
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