3JUE
| Crystal Structure of ArfGAP and ANK repeat domain of ACAP1 | 分子名称: | ARFGAP with coiled-coil, ANK repeat and PH domain-containing protein 1, SULFATE ION, ... | 著者 | Pang, X, Zhang, K, Ma, J, Zhou, Q, Sun, F. | 登録日 | 2009-09-15 | 公開日 | 2010-09-22 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Mechanistic insights into regulated cargo binding by ACAP1 protein J.Biol.Chem., 287, 2012
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3WWF
| Crystal structure of the computationally designed Pizza2-SR protein | 分子名称: | pizza2sr-pb protein | 著者 | Voet, A.R.D, Noguchi, H, Addy, C, Simoncini, D, Terada, D, Unzai, S, Park, S.Y, Zhang, K.Y.J, Tame, J.R.H. | 登録日 | 2014-06-17 | 公開日 | 2014-10-08 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | 主引用文献 | Computational design of a self-assembling symmetrical beta-propeller protein. Proc.Natl.Acad.Sci.USA, 111, 2014
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3WWB
| Crystal structure of the computationally designed Pizza2-SR protein | 分子名称: | Pizza2-SR protein | 著者 | Voet, A.R.D, Noguchi, H, Addy, C, Simoncini, D, Terada, D, Unzai, S, Park, S.Y, Zhang, K.Y.J, Tame, J.R.H. | 登録日 | 2014-06-17 | 公開日 | 2014-10-08 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Computational design of a self-assembling symmetrical beta-propeller protein. Proc.Natl.Acad.Sci.USA, 111, 2014
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3WWA
| Crystal structure of the computationally designed Pizza7 protein after heat treatment | 分子名称: | ISOPROPYL ALCOHOL, Pizza7H protein | 著者 | Voet, A.R.D, Noguchi, H, Addy, C, Simoncini, D, Terada, D, Unzai, S, Park, S.Y, Zhang, K.Y.J, Tame, J.R.H. | 登録日 | 2014-06-17 | 公開日 | 2014-10-08 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.988 Å) | 主引用文献 | Computational design of a self-assembling symmetrical beta-propeller protein. Proc.Natl.Acad.Sci.USA, 111, 2014
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3WW9
| Crystal structure of the computationally designed Pizza6 protein | 分子名称: | GLYCEROL, SULFATE ION, pizza6 protein | 著者 | Voet, A.R.D, Noguchi, H, Addy, C, Simoncini, D, Terada, D, Unzai, S, Park, S.Y, Zhang, K.Y.J, Tame, J.R.H. | 登録日 | 2014-06-17 | 公開日 | 2014-10-08 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | 主引用文献 | Computational design of a self-assembling symmetrical beta-propeller protein. Proc.Natl.Acad.Sci.USA, 111, 2014
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3WW7
| Crystal structure of the computationally designed Pizza2 protein | 分子名称: | GLYCEROL, Pizza2 protein | 著者 | Voet, A.R.D, Noguchi, H, Addy, C, Simoncini, D, Terada, D, Unzai, S, Park, S.Y, Zhang, K.Y.J, Tame, J.R.H. | 登録日 | 2014-06-17 | 公開日 | 2014-10-08 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.697 Å) | 主引用文献 | Computational design of a self-assembling symmetrical beta-propeller protein. Proc.Natl.Acad.Sci.USA, 111, 2014
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3WW8
| Crystal structure of the computationally designed Pizza3 protein | 分子名称: | GLYCEROL, Pizza3 protein, SULFATE ION | 著者 | Voet, A.R.D, Noguchi, H, Addy, C, Simoncini, D, Terada, D, Unzai, S, Park, S.Y, Zhang, K.Y.J, Tame, J.R.H. | 登録日 | 2014-06-17 | 公開日 | 2014-10-08 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.402 Å) | 主引用文献 | Computational design of a self-assembling symmetrical beta-propeller protein. Proc.Natl.Acad.Sci.USA, 111, 2014
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7E3D
| Crystal structure of human acetylcholinesterase | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, Acetylcholinesterase | 著者 | Dileep, K.V, Ihara, K, Mishima-Tsumagari, C, Kukimoto-Niino, M, Yonemochi, M, Hanada, K, Shirouzu, M, Zhang, K.Y.J. | 登録日 | 2021-02-08 | 公開日 | 2022-02-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of human acetylcholinesterase in complex with tacrine: Implications for drug discovery Int.J.Biol.Macromol., 210, 2022
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7E3H
| Crystal structure of human acetylcholinesterase in complex with donepezil | 分子名称: | 1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON-2-YL)METHYL]PIPERIDINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase | 著者 | Dileep, K.V, Ihara, K, Mishima-Tsumagari, C, Kukimoto-Niino, M, Yonemochi, M, Hanada, K, Shirouzu, M, Zhang, K.Y.J. | 登録日 | 2021-02-08 | 公開日 | 2022-02-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Crystal structure of human acetylcholinesterase in complex with tacrine: Implications for drug discovery Int.J.Biol.Macromol., 210, 2022
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8D0A
| Crystal structure of human USP30 in complex with a covalent inhibitor 829 and a Fab | 分子名称: | Ubiquitin carboxyl-terminal hydrolase 30, ZINC ION, mouse anti-huUSP30 Fab heavy chain, ... | 著者 | Song, X, Butler, J, Li, C, Zhang, K, Zhang, D, Hao, Y. | 登録日 | 2022-05-25 | 公開日 | 2023-02-01 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | 主引用文献 | TBD To Be Published
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7CFM
| Cryo-EM structure of the P395-bound GPBAR-Gs complex | 分子名称: | 2-(ethylamino)-6-[3-(4-propan-2-ylphenyl)propanoyl]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-4-carboxamide, CHOLESTEROL, G-protein coupled bile acid receptor 1, ... | 著者 | Yang, F, Mao, C, Guo, L, Lin, J, Ming, Q, Xiao, P, Wu, X, Shen, Q, Guo, S, Shen, D, Lu, R, Zhang, L, Huang, S, Ping, Y, Zhang, C, Ma, C, Zhang, K, Liang, X, Shen, Y, Nan, F, Yi, F, Luca, V, Zhou, J, Jiang, C, Sun, J, Xie, X, Yu, X, Zhang, Y. | 登録日 | 2020-06-27 | 公開日 | 2020-09-09 | 最終更新日 | 2020-12-02 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis of GPBAR activation and bile acid recognition. Nature, 587, 2020
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7CFN
| Cryo-EM structure of the INT-777-bound GPBAR-Gs complex | 分子名称: | (2S,4R)-4-[(3R,5S,6R,7R,8R,9S,10S,12S,13R,14S,17R)-6-ethyl-10,13-dimethyl-3,7,12-tris(oxidanyl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-pentanoic acid, CHOLESTEROL, G-protein coupled bile acid receptor 1, ... | 著者 | Yang, F, Mao, C, Guo, L, Lin, J, Ming, Q, Xiao, P, Wu, X, Shen, Q, Guo, S, Shen, D, Lu, R, Zhang, L, Huang, S, Ping, Y, Zhang, C, Ma, C, Zhang, K, Liang, X, Shen, Y, Nan, F, Yi, F, Luca, V, Zhou, J, Jiang, C, Sun, J, Xie, X, Yu, X, Zhang, Y. | 登録日 | 2020-06-27 | 公開日 | 2020-09-09 | 最終更新日 | 2021-04-07 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis of GPBAR activation and bile acid recognition. Nature, 587, 2020
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7FD5
| A complete three-dimensional structure of the Lon protease translocating a protein substrate (conformation 2) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Alpha-S1-casein, Lon protease, ... | 著者 | Li, S, Hsieh, K, Kuo, C, Lee, S, Pintilie, G, Zhang, K, Chang, C. | 登録日 | 2021-07-16 | 公開日 | 2021-11-03 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Complete three-dimensional structures of the Lon protease translocating a protein substrate. Sci Adv, 7, 2021
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7FD4
| A complete three-dimensional structure of the Lon protease translocating a protein substrate (conformation 1) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Alpha-S1-casein, Lon protease, ... | 著者 | Li, S, Hsieh, K, Kuo, C, Lee, S, Pintilie, G, Zhang, K, Chang, C. | 登録日 | 2021-07-16 | 公開日 | 2021-11-03 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Complete three-dimensional structures of the Lon protease translocating a protein substrate. Sci Adv, 7, 2021
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7YCH
| Cryo-EM structure of Tetrahymena ribozyme conformation 3 undergoing the first-step self-splicing | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA (393-MER), ... | 著者 | Zhang, X, Li, S, Pintilie, G, Palo, M.Z, Zhang, K. | 登録日 | 2022-07-01 | 公開日 | 2023-07-05 | 最終更新日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | 主引用文献 | Snapshots of the first-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM. Nucleic Acids Res., 51, 2023
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7YCG
| Cryo-EM structure of Tetrahymena ribozyme conformation 2 undergoing the first-step self-splicing | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA (393-MER), ... | 著者 | Zhang, X, Li, S, Pintilie, G, Palo, M.Z, Zhang, K. | 登録日 | 2022-07-01 | 公開日 | 2023-07-05 | 最終更新日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | 主引用文献 | Snapshots of the first-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM. Nucleic Acids Res., 51, 2023
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7YCI
| Cryo-EM structure of Tetrahymena ribozyme conformation 4 undergoing the first-step self-splicing | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA (389-MER), ... | 著者 | Zhang, X, Li, S, Pintilie, G, Palo, M.Z, Zhang, K. | 登録日 | 2022-07-01 | 公開日 | 2023-07-05 | 最終更新日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | 主引用文献 | Snapshots of the first-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM. Nucleic Acids Res., 51, 2023
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7YC8
| Cryo-EM structure of Tetrahymena ribozyme conformation 1 undergoing the first-step self-splicing | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, RNA (388-MER) | 著者 | Zhang, X, Li, S, Pintilie, G, Palo, M.Z, Zhang, K. | 登録日 | 2022-07-01 | 公開日 | 2023-07-05 | 最終更新日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (4.14 Å) | 主引用文献 | Snapshots of the first-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM. Nucleic Acids Res., 51, 2023
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7YG8
| Cryo-EM structure of Tetrahymena ribozyme conformation 5 undergoing the second-step self-splicing | 分子名称: | MAGNESIUM ION, RNA (387-MER), RNA (5'-R(*CP*CP*CP*UP*C)-3'), ... | 著者 | Li, S, Michael, Z.P, Zhang, X, Greg, P, Zhang, K. | 登録日 | 2022-07-11 | 公開日 | 2023-03-29 | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | 主引用文献 | Snapshots of the second-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM. Nat Commun, 14, 2023
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7YGD
| Cryo-EM structure of Tetrahymena ribozyme conformation 6 undergoing the second-step self-splicing | 分子名称: | MAGNESIUM ION, RNA (384-MER), RNA (5'-R(*CP*C)-3'), ... | 著者 | Li, S, Michael, Z.P, Zhang, X, Greg, P, Zhang, K. | 登録日 | 2022-07-11 | 公開日 | 2023-03-29 | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | 主引用文献 | Snapshots of the second-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM. Nat Commun, 14, 2023
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7YGC
| Cryo-EM structure of Tetrahymena ribozyme conformation 4 undergoing the second-step self-splicing | 分子名称: | MAGNESIUM ION, RNA (393-MER), RNA (5'-R(*CP*CP*CP*UP*CP*UP*UP*AP*AP*CP*C)-3'), ... | 著者 | Li, S, Michael, Z.P, Zhang, X, Greg, P, Zhang, K. | 登録日 | 2022-07-11 | 公開日 | 2023-03-29 | 最終更新日 | 2023-04-05 | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | 主引用文献 | Snapshots of the second-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM. Nat Commun, 14, 2023
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4MAL
| TPR3 of FimV from P. aeruginosa (PAO1) | 分子名称: | Motility protein FimV | 著者 | Nguyen, Y, Zhang, K, Daniel-Ivad, M, Sugiman-Marangos, S.N, Junop, M.S, Burrows, L.L, Howell, P.L. | 登録日 | 2013-08-16 | 公開日 | 2014-08-20 | 最終更新日 | 2016-02-24 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Crystal structure of TPR2 from FimV To be Published
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4OIY
| Crystal structure of Sec7p catalytic domain | 分子名称: | MAGNESIUM ION, Protein transport protein SEC7 | 著者 | Qiu, B, Zhang, K, Sun, F. | 登録日 | 2014-01-20 | 公開日 | 2014-07-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | C-terminal motif within Sec7 domain regulates guanine nucleotide exchange activity via tuning protein conformation Biochem.Biophys.Res.Commun., 446, 2014
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7FIZ
| Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex (conformation 3) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lon protease, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | 著者 | Li, S, Hsieh, K, Kuo, C, Su, S, Huang, K, Zhang, K, Chang, C.I. | 登録日 | 2021-08-01 | 公開日 | 2021-11-24 | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | 主引用文献 | Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex. Sci Adv, 7, 2021
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7FIE
| Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex (conformation 2) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lon protease, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | 著者 | Li, S, Hsieh, K, Kuo, C, Su, S, Huang, K, Zhang, K, Chang, C.I. | 登録日 | 2021-07-31 | 公開日 | 2021-11-24 | 実験手法 | ELECTRON MICROSCOPY (2.36 Å) | 主引用文献 | Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex. Sci Adv, 7, 2021
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