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PDB: 726 件

1AAX
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CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH TWO BIS(PARA-PHOSPHOPHENYL)METHANE (BPPM) MOLECULES
分子名称: 4-PHOSPHONOOXY-PHENYL-METHYL-[4-PHOSPHONOOXY]BENZEN, MAGNESIUM ION, PROTEIN TYROSINE PHOSPHATASE 1B
著者Puius, Y.A, Zhao, Y, Sullivan, M, Lawrence, D, Almo, S.C, Zhang, Z.-Y.
登録日1997-01-16
公開日1998-03-04
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Identification of a second aryl phosphate-binding site in protein-tyrosine phosphatase 1B: a paradigm for inhibitor design.
Proc.Natl.Acad.Sci.USA, 94, 1997
8WX4
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Cryo-EM structure of human SLC15A4 in complex with Lys-Leu (outward-facing open)
分子名称: LEUCINE, LYSINE, Solute carrier family 15 member 4
著者Sakaniwa, K, Zhang, Z, Ohto, U, Shimizu, T.
登録日2023-10-27
公開日2023-12-13
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Cryo-EM structure of human SLC15A4 in complex with Lys-Leu (outward-facing open)
To Be Published
8WX3
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Cryo-EM structure of human SLC15A4 (outward-facing open)
分子名称: Solute carrier family 15 member 4
著者Sakaniwa, K, Zhang, Z, Ohto, U, Shimizu, T.
登録日2023-10-27
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (2.83 Å)
主引用文献Cryo-EM structure of human SLC15A4 (outward-facing open)
To Be Published
8WX2
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Cryo-EM structure of human SLC15A3 (dimer)
分子名称: Solute carrier family 15 member 3
著者Kasai, S, Zhang, Z, Ohto, U, Shimizu, T.
登録日2023-10-27
公開日2023-12-06
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.44 Å)
主引用文献Cryo-EM structure of human SLC15A3 (outward-facing partially occluded)
To Be Published
8WX5
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Cryo-EM structure of human SLC15A4 in complex with TASL (inward-facing open)
分子名称: Solute carrier family 15 member 4, TASL (TASL-SLC15A4 fusion protein)
著者Ohto, U, Zhang, Z, Fujimura, A, Shimizu, T.
登録日2023-10-27
公開日2023-12-13
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Cryo-EM structure of human SLC15A4 in complex with TASL (inward-facing open)
To Be Published
6S8N
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Cryo-EM structure of LptB2FGC in complex with lipopolysaccharide
分子名称: 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, DODECYL-BETA-D-MALTOSIDE, Inner membrane protein yjgQ, ...
著者Tang, X.D, Chang, S.H, Luo, Q.H, Zhang, Z.Y, Qiao, W, Xu, C.H, Zhang, C.B, Niu, Y, Yang, W.X, Wang, T, Zhang, Z.B, Zhu, X.F, Dong, C.J, Zhang, X, Dong, H.H.
登録日2019-07-10
公開日2019-09-25
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM structures of lipopolysaccharide transporter LptB2FGC in lipopolysaccharide or AMP-PNP-bound states reveal its transport mechanism.
Nat Commun, 10, 2019
6S8H
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Cryo-EM structure of LptB2FG in complex with LPS
分子名称: (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-5-[(2~{S},3~{S},4~{R},5~{R},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-4-[(2~{R},3~{S},4~{R},5~{S},6~{R})-6-[(1~{S})-2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-1-oxidanyl-ethyl]-3,4-bis(oxidanyl)-5-phosphonooxy-oxan-2-yl]oxy-3-oxidanyl-5-phosphonooxy-oxan-2-yl]oxy-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, DODECYL-BETA-D-MALTOSIDE, ...
著者Tang, X.D, Chang, S.H, Luo, Q.H, Zhang, Z.Y, Qiao, W, Xu, C.H, Zhang, C.B, Niu, Y, Yang, W.X, Wang, T, Zhang, Z.B, Zhu, X.F, Dong, C.J, Zhang, X, Dong, H.H.
登録日2019-07-10
公開日2019-09-25
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM structures of lipopolysaccharide transporter LptB2FGC in lipopolysaccharide or AMP-PNP-bound states reveal its transport mechanism.
Nat Commun, 10, 2019
6S8G
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Cryo-EM structure of LptB2FGC in complex with AMP-PNP
分子名称: Inner membrane protein yjgQ, LPS export ABC transporter permease LptF, Lipopolysaccharide ABC transporter, ...
著者Tang, X.D, Chang, S.H, Luo, Q.H, Zhang, Z.Y, Qiao, W, Xu, C.H, Zhang, C.B, Niu, Y, Yang, W.X, Wang, T, Zhang, Z.B, Zhu, X.F, Dong, C.J, Zhang, X, Dong, H.H.
登録日2019-07-10
公開日2019-09-25
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structures of lipopolysaccharide transporter LptB2FGC in lipopolysaccharide or AMP-PNP-bound states reveal its transport mechanism.
Nat Commun, 10, 2019
6LK3
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The Functional Characterization and Crystal Structure of Type II Peptidyl Carrier Protein ColA1a in Collismycins Biosynthesis
分子名称: Putative free-standing acyl carrier protein
著者Ma, X.Y, Wang, G.Y, Liu, T, Chi, C.B, Zhang, Z.Y, Yang, D.H, Liu, W, Ma, M.
登録日2019-12-18
公開日2020-10-28
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The functional characterization and crystal structure of type II peptidyl carrier protein ColA1a in collismycins biosynthesis.
Chin.J.Chem., 38, 2020
6GYU
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Cryo-EM structure of the CBF3-msk complex of the budding yeast kinetochore
分子名称: Centromere DNA-binding protein complex CBF3 subunit A, Centromere DNA-binding protein complex CBF3 subunit B, Centromere DNA-binding protein complex CBF3 subunit C, ...
著者Yan, K, Zhang, Z, Yang, J, McLaughlin, S.H, Barford, D.
登録日2018-07-02
公開日2018-12-05
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Architecture of the CBF3-centromere complex of the budding yeast kinetochore.
Nat. Struct. Mol. Biol., 25, 2018
6GYS
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Cryo-EM structure of the CBF3-CEN3 complex of the budding yeast kinetochore
分子名称: Centromere DNA-binding protein complex CBF3 subunit A, Centromere DNA-binding protein complex CBF3 subunit B, Centromere DNA-binding protein complex CBF3 subunit C, ...
著者Yan, K, Zhang, Z, Yang, J, McLaughlin, S.H, Barford, D.
登録日2018-07-01
公開日2018-12-05
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Architecture of the CBF3-centromere complex of the budding yeast kinetochore.
Nat. Struct. Mol. Biol., 25, 2018
6GYP
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Cryo-EM structure of the CBF3-core-Ndc10-DBD complex of the budding yeast kinetochore
分子名称: ARGININE, ASPARAGINE, Centromere DNA-binding protein complex CBF3 subunit A, ...
著者Yan, K, Zhang, Z, Yang, J, McLaughlin, S.H, Barford, D.
登録日2018-07-01
公開日2018-12-05
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Architecture of the CBF3-centromere complex of the budding yeast kinetochore.
Nat. Struct. Mol. Biol., 25, 2018
4UI9
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Atomic structure of the human Anaphase-Promoting Complex
分子名称: ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ...
著者Chang, L, Zhang, Z, Yang, J, McLaughlin, S.H, Barford, D.
登録日2015-03-27
公開日2015-06-17
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Atomic Structure of the Apc and its Mechanism of Protein Ubiquitination
Nature, 522, 2015
1JOT
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STRUCTURE OF THE LECTIN MPA COMPLEXED WITH T-ANTIGEN DISACCHARIDE
分子名称: AGGLUTININ, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose
著者Lee, X, Thompson, A, Zhang, Z, Hoa, T.-T, Biesterfeldt, J, Ogata, C, Xu, L, Johnston, R.A.Z, Young, N.M.
登録日1997-12-05
公開日1998-12-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the complex of Maclura pomifera agglutinin and the T-antigen disaccharide, Galbeta1,3GalNAc.
J.Biol.Chem., 273, 1998
7ARM
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LolCDE in complex with lipoprotein and LolA
分子名称: (2S)-3-hydroxypropane-1,2-diyl dihexadecanoate, LPP, Lipoprotein-releasing ABC transporter permease subunit LolC, ...
著者Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Shen, C.R, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Wei, X.W, Dong, C.J, Zhang, X, Dong, H.H.
登録日2020-10-25
公開日2021-04-07
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
7ARL
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LolCDE in complex with lipoprotein and ADP
分子名称: (2S)-3-hydroxypropane-1,2-diyl dihexadecanoate, ADENOSINE-5'-DIPHOSPHATE, LPP, ...
著者Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Shen, C.R, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Wei, X.W, Dong, C.J, Zhang, X, Dong, H.H.
登録日2020-10-25
公開日2021-04-07
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
7ARK
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LolCDE in complex with AMP-PNP in the closed NBD state
分子名称: Lipoprotein-releasing ABC transporter permease subunit LolC, Lipoprotein-releasing system ATP-binding protein LolD, Lipoprotein-releasing system transmembrane protein LolE, ...
著者Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Dong, C.J, Zhang, X, Dong, H.H.
登録日2020-10-25
公開日2021-04-07
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
7ARJ
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LolCDE in complex with lipoprotein and AMPPNP complex undimerized form
分子名称: (2S)-3-hydroxypropane-1,2-diyl dihexadecanoate, LPP, Lipoprotein-releasing ABC transporter permease subunit LolC, ...
著者Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Dong, C.J, Zhang, X, Dong, H.H.
登録日2020-10-25
公開日2021-04-07
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
7ARI
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LolCDE apo structure
分子名称: Lipoprotein-releasing ABC transporter permease subunit LolC, Lipoprotein-releasing system ATP-binding protein LolD, Lipoprotein-releasing system transmembrane protein LolE
著者Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Dong, C.J, Zhang, X, Dong, H.H.
登録日2020-10-25
公開日2021-04-07
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
7ARH
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LolCDE in complex with lipoprotein
分子名称: (2S)-3-hydroxypropane-1,2-diyl dihexadecanoate, LPP, Lipoprotein-releasing ABC transporter permease subunit LolC, ...
著者Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Dong, C.J, Zhang, X, Dong, H.H.
登録日2020-10-25
公開日2021-04-07
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
7QE7
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High-resolution structure of the Anaphase-promoting complex/cyclosome (APC/C) bound to co-activator Cdh1
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Hoefler, A, Yu, J, Chang, L, Zhang, Z, Yang, J, Boland, A, Barford, D.
登録日2021-12-01
公開日2022-01-26
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献High-resolution structure of the Anaphase-promoting complex (APC/C) bound to co-activator Cdh1
To Be Published
6YPC
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Crystal structure of the kinetochore subunits H/I/K/T/W penta-complex from S. cerevisiae at 2.9 angstroms
分子名称: Inner kinetochore subunit CNN1, Inner kinetochore subunit CTF3, Inner kinetochore subunit MCM16, ...
著者Bellini, D, Zhang, Z, Barford, D.
登録日2020-04-15
公開日2020-09-16
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of the Cenp-HIKHead-TW sub-module of the inner kinetochore CCAN complex.
Nucleic Acids Res., 48, 2020
8GS4
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Cryo-EM structure of human Neuroligin 2
分子名称: Neuroligin-2
著者Zhang, H, Zhang, Z, Hou, M.
登録日2022-09-04
公開日2023-03-01
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Expression and structural analysis of human neuroligin 2 and neuroligin 3 implicated in autism spectrum disorders.
Front Endocrinol, 13, 2022
7O5N
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Crystal Structure of a Class D carbapenemase complexed with Avibactam
分子名称: (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, 1-BUTANOL, Beta-lactamase, ...
著者Zhou, Q, Zhang, Z, He, Y, Jin, Y.
登録日2021-04-09
公開日2022-04-20
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献An Ion-Pair Induced Intermediate Complex Captured in Class D Carbapenemase Reveals Chloride Ion as a Janus Effector Modulating Activity
Acs Cent.Sci., 2023
1ZCL
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prl-1 c104s mutant in complex with sulfate
分子名称: SULFATE ION, protein tyrosine phosphatase 4a1
著者Sun, J.P, Wang, W.Q, Yang, H, Liu, S, Liang, F, Fedorov, A.A, Almo, S.C, Zhang, Z.Y.
登録日2005-04-12
公開日2005-09-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure and Biochemical Properties of PRL-1, a Phosphatase Implicated in Cell Growth, Differentiation, and Tumor Invasion.
Biochemistry, 44, 2005

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