8INE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ine by Molmil](/molmil-images/mine/8ine) | |
8IDY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8idy by Molmil](/molmil-images/mine/8idy) | |
8IE3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ie3 by Molmil](/molmil-images/mine/8ie3) | human nuclear pre-60S ribosomal particle - State E | Descriptor: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Zhang, Y, Gao, N. | Deposit date: | 2023-02-15 | Release date: | 2023-08-09 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles. Cell Res., 33, 2023
|
|
8IPD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ipd by Molmil](/molmil-images/mine/8ipd) | human nuclear pre-60S ribosomal particle - State C | Descriptor: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Zhang, Y, Gao, N. | Deposit date: | 2023-03-14 | Release date: | 2023-08-09 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles. Cell Res., 33, 2023
|
|
8IR3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ir3 by Molmil](/molmil-images/mine/8ir3) | |
8IDT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8idt by Molmil](/molmil-images/mine/8idt) | human nuclear pre-60S ribosomal particle - State G | Descriptor: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Zhang, Y, Gao, N. | Deposit date: | 2023-02-14 | Release date: | 2023-08-09 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles. Cell Res., 33, 2023
|
|
8IR1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ir1 by Molmil](/molmil-images/mine/8ir1) | human nuclear pre-60S ribosomal particle - State A | Descriptor: | 28S rRNA, 5.8S rRMA, 5S RNA, ... | Authors: | Zhang, Y, Gao, N. | Deposit date: | 2023-03-17 | Release date: | 2023-08-09 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles. Cell Res., 33, 2023
|
|
6Y5A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6y5a by Molmil](/molmil-images/mine/6y5a) | Serotonin-bound 5-HT3A receptor in Salipro | Descriptor: | 5-hydroxytryptamine receptor 3A, SEROTONIN | Authors: | Zhang, Y, Dijkman, P.M, Zou, R, Zandl-Lang, M, Sanchez, R.M, Eckhardt-Strelau, L, Koefeler, H, Vogel, H, Yuan, S, Kudryashev, M. | Deposit date: | 2020-02-25 | Release date: | 2020-12-23 | Last modified: | 2021-03-03 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Asymmetric opening of the homopentameric 5-HT 3A serotonin receptor in lipid bilayers. Nat Commun, 12, 2021
|
|
5GXF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5gxf by Molmil](/molmil-images/mine/5gxf) | |
2A7Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2a7q by Molmil](/molmil-images/mine/2a7q) | Crystal structure of human dCK complexed with clofarabine and ADP | Descriptor: | 2-CHLORO-9-(2-DEOXY-2-FLUORO-B -D-ARABINOFURANOSYL)-9H-PURIN-6-AMINE, ADENOSINE-5'-DIPHOSPHATE, Deoxycytidine kinase, ... | Authors: | Zhang, Y, Secrist III, J.A, Ealick, S.E. | Deposit date: | 2005-07-05 | Release date: | 2006-01-24 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | The structure of human deoxycytidine kinase in complex with clofarabine reveals key interactions for prodrug activation. Acta Crystallogr.,Sect.D, 62, 2006
|
|
1TG8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1tg8 by Molmil](/molmil-images/mine/1tg8) | The structure of Dengue virus E glycoprotein | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, envelope glycoprotein | Authors: | Zhang, Y, Zhang, W, Ogata, S, Clements, D, Strauss, J.H, Baker, T.S, Rossmann, M.G. | Deposit date: | 2004-05-28 | Release date: | 2004-09-28 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Conformational changes of the flavivirus e glycoprotein Structure, 12, 2004
|
|
5X21
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5x21 by Molmil](/molmil-images/mine/5x21) | Crystal structure of Thermus thermophilus transcription initiation complex with GpA and pseudouridimycin (PUM) | Descriptor: | (1S)-1,4-anhydro-5-[(N-carbamimidoylglycyl-N~2~-hydroxy-L-glutaminyl)amino]-5-deoxy-1-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-D-ribitol, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Zhang, Y, Ebright, R. | Deposit date: | 2017-01-29 | Release date: | 2017-07-05 | Last modified: | 2022-10-12 | Method: | X-RAY DIFFRACTION (3.323 Å) | Cite: | Antibacterial Nucleoside-Analog Inhibitor of Bacterial RNA Polymerase. Cell, 169, 2017
|
|
5X22
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5x22 by Molmil](/molmil-images/mine/5x22) | |
6A9D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6a9d by Molmil](/molmil-images/mine/6a9d) | |
1PQN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1pqn by Molmil](/molmil-images/mine/1pqn) | dominant negative human hDim1 (hDim1 1-128) | Descriptor: | Spliceosomal U5 snRNP-specific 15 kDa protein | Authors: | Zhang, Y.Z, Cheng, H, Gould, K.L, Golemis, E.A, Roder, H. | Deposit date: | 2003-06-18 | Release date: | 2003-08-26 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure, stability and function of hDim1 investigated by NMR, circular
dichroism and mutational analysis Biochemistry, 42, 2003
|
|
7EO8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7eo8 by Molmil](/molmil-images/mine/7eo8) | Crystal structure of SARS coronavirus main protease in complex with an inhibitor Shikonin | Descriptor: | 2-[(1R)-4-methyl-1-oxidanyl-pent-3-enyl]-5,8-bis(oxidanyl)naphthalene-1,4-dione, 3C-like proteinase | Authors: | Zhang, Y.T, Gao, H.X, Zhou, H, Zhong, F.L, Hu, X.H, Zhou, X.L, Lin, C, Wang, Q.S, Li, J, Zhang, J. | Deposit date: | 2021-04-21 | Release date: | 2021-10-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2808516 Å) | Cite: | Structure-Based Discovery and Structural Basis of a Novel Broad-Spectrum Natural Product against the Main Protease of Coronavirus. J.Virol., 96, 2022
|
|
6KTH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6kth by Molmil](/molmil-images/mine/6kth) | Crystal structure of Juvenile hormone diol kinase JHDK-L2 from silkworm, Bombyx mori | Descriptor: | CALCIUM ION, GLYCEROL, Juvenile hormone diol kinase | Authors: | Zhang, Y.S, Xu, H.Y, Wang, Z, Zhang, L, Zhao, P, Guo, P.C. | Deposit date: | 2019-08-28 | Release date: | 2020-09-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.22 Å) | Cite: | Structural characterization and functional analysis of juvenile hormone diol kinase from the silkworm, Bombyx mori. Int.J.Biol.Macromol., 167, 2021
|
|
1O7O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1o7o by Molmil](/molmil-images/mine/1o7o) | Roles of Individual Residues of Alpha-1,3 Galactosyltransferases in Substrate Binding and Catalysis | Descriptor: | MANGANESE (II) ION, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE, ... | Authors: | Zhang, Y, Swaminathan, G.J, Deshpande, A, Natesh, R, Xie, Z, Acharya, K.R, Brew, K. | Deposit date: | 2002-11-11 | Release date: | 2003-11-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Roles of individual enzyme-substrate interactions by alpha-1,3-galactosyltransferase in catalysis and specificity. Biochemistry, 42, 2003
|
|
1O7Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1o7q by Molmil](/molmil-images/mine/1o7q) | Roles of Individual Residues of Alpha-1,3 Galactosyltransferases in Substrate Binding and Catalysis | Descriptor: | GLYCEROL, MANGANESE (II) ION, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, ... | Authors: | Zhang, Y, Swaminathan, G.J, Deshpande, A, Natesh, R, Xie, Z, Acharya, K.R, Brew, K. | Deposit date: | 2002-11-12 | Release date: | 2003-11-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Roles of Individual Enzyme-Substrate Interactions by Alpha-1,3-Galactosyltransferase in Catalysis and Specificity. Biochemistry, 42, 2003
|
|
6BGN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6bgn by Molmil](/molmil-images/mine/6bgn) | Crystal Structure of 4-Oxalocrotonate Tautomerase After Incubation with 5-Fluoro-2-hydroxy-2,4-pentadienoate | Descriptor: | 2-hydroxymuconate tautomerase, 5-fluoranyl-2-oxidanylidene-pentanoic acid, GLYCEROL, ... | Authors: | Zhang, Y, Li, W, Stack, T. | Deposit date: | 2017-10-29 | Release date: | 2018-02-21 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Inactivation of 4-Oxalocrotonate Tautomerase by 5-Halo-2-hydroxy-2,4-pentadienoates. Biochemistry, 57, 2018
|
|
6N33
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6n33 by Molmil](/molmil-images/mine/6n33) | Crystal structure of fms kinase domain with a small molecular inhibitor, PLX5622 | Descriptor: | 6-fluoro-N-[(5-fluoro-2-methoxypyridin-3-yl)methyl]-5-[(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]pyridin-2-amine, Macrophage colony-stimulating factor 1 receptor | Authors: | Zhang, Y. | Deposit date: | 2018-11-14 | Release date: | 2019-09-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer's disease model. Nat Commun, 10, 2019
|
|
7DQZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7dqz by Molmil](/molmil-images/mine/7dqz) | Crystal structure of SARS 3C-like protease in apo form | Descriptor: | 3C-like proteinase | Authors: | Zhang, Y.T, Gao, H.X, Zhou, H, Zhong, F.L, Hu, X.H, Zhou, X.L, Lin, C, Wang, Q.S, Li, J, Zhang, J. | Deposit date: | 2020-12-24 | Release date: | 2021-09-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structure-Based Discovery and Structural Basis of a Novel Broad-Spectrum Natural Product against the Main Protease of Coronavirus. J.Virol., 96, 2022
|
|
1VZU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1vzu by Molmil](/molmil-images/mine/1vzu) | Roles of active site tryptophans in substrate binding and catalysis by ALPHA-1,3 GALACTOSYLTRANSFERASE | Descriptor: | GLYCEROL, MANGANESE (II) ION, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, ... | Authors: | Zhang, Y, Deshpande, A, Xie, Z, Natesh, R, Acharya, K.R, Brew, K. | Deposit date: | 2004-05-27 | Release date: | 2004-07-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Roles of active site tryptophans in substrate binding and catalysis by alpha-1,3 galactosyltransferase. Glycobiology, 14, 2004
|
|
5HYN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5hyn by Molmil](/molmil-images/mine/5hyn) | Structure of Human Polycomb Repressive Complex 2 (PRC2) with oncogenic histone H3K27M peptide | Descriptor: | H3K27M, Histone-lysine N-methyltransferase EZH2, JARID2 K116me3, ... | Authors: | Zhang, Y, Justin, N, Wilson, J.R, Gamblin, S.J. | Deposit date: | 2016-02-01 | Release date: | 2016-05-11 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structural basis of oncogenic histone H3K27M inhibition of human polycomb repressive complex 2. Nat Commun, 7, 2016
|
|
1VZX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1vzx by Molmil](/molmil-images/mine/1vzx) | Roles of active site tryptophans in substrate binding and catalysis by ALPHA-1,3 GALACTOSYLTRANSFERASE | Descriptor: | GLYCEROL, MANGANESE (II) ION, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, ... | Authors: | Zhang, Y, Deshpande, A, Xie, Z, Natesh, R, Acharya, K.R, Brew, K. | Deposit date: | 2004-05-28 | Release date: | 2004-07-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Roles of active site tryptophans in substrate binding and catalysis by alpha-1,3 galactosyltransferase. Glycobiology, 14, 2004
|
|