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PDB: 1681 件

3OMX
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Crystal structure of Ssu72 with vanadate complex
分子名称: CG14216, VANADATE ION
著者Zhang, Y, Zhang, M, Zhang, Y.
登録日2010-08-27
公開日2011-01-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3366 Å)
主引用文献Crystal structure of Ssu72, an essential eukaryotic phosphatase specific for the C-terminal domain of RNA polymerase II, in complex with a transition state analogue.
Biochem.J., 434, 2011
5D4D
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BU of 5d4d by Molmil
Crystal structure of Thermus thermophilus product complex for transcription initiation with NAD and CTP
分子名称: ADENOSINE MONOPHOSPHATE, CYTIDINE-5'-MONOPHOSPHATE, CYTIDINE-5'-TRIPHOSPHATE, ...
著者Zhang, Y, Ebright, R.H.
登録日2015-08-07
公開日2016-07-06
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The mechanism of RNA 5' capping with NAD(+), NADH and desphospho-CoA.
Nature, 535, 2016
5TIG
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BU of 5tig by Molmil
CRYSTAL STRUCTURE OF 4-OXALOCROTONATE TAUTOMERASE INACTIVATED BY BrHPD
分子名称: (3E)-5-hydroxy-2-oxopent-3-enoic acid, 2-hydroxymuconate tautomerase
著者Zhang, Y, Li, W, Stack, T.
登録日2016-10-02
公開日2018-02-21
最終更新日2019-04-17
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Inactivation of 4-Oxalocrotonate Tautomerase by 5-Halo-2-hydroxy-2,4-pentadienoates.
Biochemistry, 57, 2018
5D4C
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BU of 5d4c by Molmil
Crystal structure of Thermus thermophilus product complex for transcription initiation with ATP and CTP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CYTIDINE-5'-MONOPHOSPHATE, CYTIDINE-5'-TRIPHOSPHATE, ...
著者Zhang, Y, Ebright, R.H.
登録日2015-08-07
公開日2016-07-06
最終更新日2024-07-03
実験手法X-RAY DIFFRACTION (3.28 Å)
主引用文献The mechanism of RNA 5' capping with NAD(+), NADH and desphospho-CoA.
Nature, 535, 2016
1TG8
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BU of 1tg8 by Molmil
The structure of Dengue virus E glycoprotein
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, envelope glycoprotein
著者Zhang, Y, Zhang, W, Ogata, S, Clements, D, Strauss, J.H, Baker, T.S, Rossmann, M.G.
登録日2004-05-28
公開日2004-09-28
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Conformational changes of the flavivirus e glycoprotein
Structure, 12, 2004
1VZU
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BU of 1vzu by Molmil
Roles of active site tryptophans in substrate binding and catalysis by ALPHA-1,3 GALACTOSYLTRANSFERASE
分子名称: GLYCEROL, MANGANESE (II) ION, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, ...
著者Zhang, Y, Deshpande, A, Xie, Z, Natesh, R, Acharya, K.R, Brew, K.
登録日2004-05-27
公開日2004-07-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Roles of active site tryptophans in substrate binding and catalysis by alpha-1,3 galactosyltransferase.
Glycobiology, 14, 2004
7EN5
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BU of 7en5 by Molmil
The crystal structure of Escherichia coli MurR in complex with N-acetylglucosamine-6-phosphate
分子名称: 2-METHOXYETHANOL, 2-acetamido-2-deoxy-6-O-phosphono-beta-D-glucopyranose, GLYCEROL, ...
著者Zhang, Y, Chen, W, Ji, Q.
登録日2021-04-16
公開日2022-04-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Molecular basis for cell-wall recycling regulation by transcriptional repressor MurR in Escherichia coli.
Nucleic Acids Res., 50, 2022
7EN7
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BU of 7en7 by Molmil
The crystal structure of Escherichia coli MurR in complex with N-acetylmuramic-acid-6-phosphate
分子名称: (2R)-2-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-bis(oxidanyl)-6-(phosphonooxymethyl)oxan-4-yl]oxypropanoic acid, HTH-type transcriptional regulator MurR
著者Zhang, Y, Chen, W, Ji, Q.
登録日2021-04-16
公開日2022-04-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.22 Å)
主引用文献Molecular basis for cell-wall recycling regulation by transcriptional repressor MurR in Escherichia coli.
Nucleic Acids Res., 50, 2022
7KHJ
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BU of 7khj by Molmil
Crystal structure of KIT kinase domain with a small molecule inhibitor, PLX8512 in the DFG-in state
分子名称: 2-phenyl-5-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine, Mast/stem cell growth factor receptor Kit
著者Zhang, Y.
登録日2020-10-21
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Association of Combination of Conformation-Specific KIT Inhibitors With Clinical Benefit in Patients With Refractory Gastrointestinal Stromal Tumors: A Phase 1b/2a Nonrandomized Clinical Trial.
Jama Oncol, 7, 2021
7KHK
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Crystal structure of KIT kinase domain with a small molecule inhibitor, PLX9486 (bezuclastinib) in the DFG-in state
分子名称: 4,5-dimethyl-N-(2-phenyl-1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazole-3-carboxamide, Mast/stem cell growth factor receptor Kit
著者Zhang, Y.
登録日2020-10-21
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Association of Combination of Conformation-Specific KIT Inhibitors With Clinical Benefit in Patients With Refractory Gastrointestinal Stromal Tumors: A Phase 1b/2a Nonrandomized Clinical Trial.
Jama Oncol, 7, 2021
7KHG
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BU of 7khg by Molmil
Crystal structure of KIT kinase domain with a small molecule inhibitor, PLX3397
分子名称: 5-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-N-{[6-(trifluoromethyl)pyridin-3-yl]methyl}pyridin-2-amine, Mast/stem cell growth factor receptor Kit
著者Zhang, Y.
登録日2020-10-21
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Association of Combination of Conformation-Specific KIT Inhibitors With Clinical Benefit in Patients With Refractory Gastrointestinal Stromal Tumors: A Phase 1b/2a Nonrandomized Clinical Trial.
Jama Oncol, 7, 2021
5KXF
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BU of 5kxf by Molmil
Crystal structure of the SPOC domain of the Arabidopsis flowering regulator FPA
分子名称: Flowering time control protein FPA
著者Zhang, Y, Tong, L.
登録日2016-07-20
公開日2016-10-12
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structure of the SPOC Domain of the Arabidopsis Flowering Regulator FPA.
Plos One, 11, 2016
1O7O
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BU of 1o7o by Molmil
Roles of Individual Residues of Alpha-1,3 Galactosyltransferases in Substrate Binding and Catalysis
分子名称: MANGANESE (II) ION, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE, ...
著者Zhang, Y, Swaminathan, G.J, Deshpande, A, Natesh, R, Xie, Z, Acharya, K.R, Brew, K.
登録日2002-11-11
公開日2003-11-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Roles of individual enzyme-substrate interactions by alpha-1,3-galactosyltransferase in catalysis and specificity.
Biochemistry, 42, 2003
9ATN
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BU of 9atn by Molmil
NMR structure of the MLL4 PHD2/3 fingers in complex with ASXL2
分子名称: Histone-lysine N-methyltransferase 2D, Polycomb group protein ASXL2, ZINC ION
著者Zhang, Y, Zandian, M, Kutateladze, T.
登録日2024-02-27
公開日2024-06-19
実験手法SOLUTION NMR
主引用文献ASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers.
Nat Commun, 15, 2024
1O7Q
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BU of 1o7q by Molmil
Roles of Individual Residues of Alpha-1,3 Galactosyltransferases in Substrate Binding and Catalysis
分子名称: GLYCEROL, MANGANESE (II) ION, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, ...
著者Zhang, Y, Swaminathan, G.J, Deshpande, A, Natesh, R, Xie, Z, Acharya, K.R, Brew, K.
登録日2002-11-12
公開日2003-11-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Roles of Individual Enzyme-Substrate Interactions by Alpha-1,3-Galactosyltransferase in Catalysis and Specificity.
Biochemistry, 42, 2003
5JKF
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BU of 5jkf by Molmil
Crystal structure of esterase E22
分子名称: Esterase E22
著者Zhang, Y, Wang, P, Yao, Q.
登録日2016-04-26
公開日2017-04-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.393 Å)
主引用文献Structural basis for substrate recognition and catalysis of a novel esterase E22 with a homoserine transacetylase-like fold
To Be Published
6M0W
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BU of 6m0w by Molmil
Crystal structure of Streptococcus thermophilus Cas9 in complex with the AGAA PAM
分子名称: CRISPR-associated endonuclease Cas9 1, DNA (28-MER), DNA (5'-D(*AP*AP*AP*GP*AP*AP*GP*C)-3'), ...
著者Zhang, Y, Zhang, H, Xu, X, Wang, Y, Chen, W, Wang, Y, Wu, Z, Tang, N, Wang, Y, Zhao, S, Gan, J, Ji, Q.
登録日2020-02-23
公開日2020-09-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Catalytic-state structure and engineering of Streptococcus thermophilus Cas9
Nat Catal, 2020
5JKJ
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Crystal structure of esterase E22 L374D mutant
分子名称: Esterase E22
著者Zhang, Y, Wang, P, Yao, Q.
登録日2016-04-26
公開日2017-04-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural basis for substrate recognition and catalysis of a novel esterase E22 with a homoserine transacetylase-like fold
To Be Published
6M0X
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BU of 6m0x by Molmil
Crystal structure of Streptococcus thermophilus Cas9 in complex with AGGA PAM
分子名称: BARIUM ION, CRISPR-associated endonuclease Cas9 1, DNA (28-MER), ...
著者Zhang, Y, Zhang, H, Xu, X, Wang, Y, Chen, W, Wang, Y, Wu, Z, Tang, N, Wang, Y, Zhao, S, Gan, J, Ji, Q.
登録日2020-02-23
公開日2020-09-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.561 Å)
主引用文献Catalytic-state structure and engineering of Streptococcus thermophilus Cas9
Nat Catal, 2020
6M0V
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BU of 6m0v by Molmil
Crsytal structure of streptococcus thermophilus Cas9 in complex with the GGAA PAM
分子名称: BARIUM ION, CRISPR-associated endonuclease Cas9 1, DNA (28-MER), ...
著者Zhang, Y, Zhang, H, Xu, X, Wang, Y, Chen, W, Wang, Y, Wu, Z, Tang, N, Wang, Y, Zhao, S, Gan, J, Ji, Q.
登録日2020-02-22
公開日2020-09-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Catalytic-state structure and engineering of Streptococcus thermophilus Cas9
Nat Catal, 2020
1PQN
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BU of 1pqn by Molmil
dominant negative human hDim1 (hDim1 1-128)
分子名称: Spliceosomal U5 snRNP-specific 15 kDa protein
著者Zhang, Y.Z, Cheng, H, Gould, K.L, Golemis, E.A, Roder, H.
登録日2003-06-18
公開日2003-08-26
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure, stability and function of hDim1 investigated by NMR, circular dichroism and mutational analysis
Biochemistry, 42, 2003
7CZH
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BU of 7czh by Molmil
PL24 ulvan lyase-Uly1
分子名称: CALCIUM ION, GLYCEROL, Uly1
著者Zhang, Y.Z, Chen, X.L, Dong, F, Xu, F.
登録日2020-09-08
公開日2021-04-07
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.104 Å)
主引用文献Mechanistic Insights into Substrate Recognition and Catalysis of a New Ulvan Lyase of Polysaccharide Lyase Family 24.
Appl.Environ.Microbiol., 87, 2021
4LA2
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BU of 4la2 by Molmil
Crystal structure of dimethylsulphoniopropionate (DMSP) lyase DddQ
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Dimethylsulphoniopropionate (DMSP) lyase DddQ, ZINC ION
著者Zhang, Y, Li, C.
登録日2013-06-19
公開日2014-01-15
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Molecular insight into bacterial cleavage of oceanic dimethylsulfoniopropionate into dimethyl sulfide
Proc.Natl.Acad.Sci.USA, 111, 2014
4LA3
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BU of 4la3 by Molmil
Crystal structure of dimethylsulphoniopropionate (DMSP) lyase DddQ Y131A in complex with DMSP
分子名称: 3-(dimethyl-lambda~4~-sulfanyl)propanoic acid, Dimethylsulphoniopropionate (DMSP) lyase DddQ, ZINC ION
著者Zhang, Y, Li, C.
登録日2013-06-19
公開日2014-01-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.701 Å)
主引用文献Molecular insight into bacterial cleavage of oceanic dimethylsulfoniopropionate into dimethyl sulfide
Proc.Natl.Acad.Sci.USA, 111, 2014
1TGE
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BU of 1tge by Molmil
The structure of immature Dengue virus at 12.5 angstrom
分子名称: envelope glycoprotein
著者Zhang, Y, Zhang, W, Ogata, S, Clements, D, Strauss, J.H, Baker, T.S, Kuhn, R.J, Rossmann, M.G.
登録日2004-05-28
公開日2004-09-28
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (12.5 Å)
主引用文献Conformational changes of the flavivirus e glycoprotein.
Structure, 12, 2004

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