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PDB: 1643 件

8I2G
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FSHR-Follicle stimulating hormone-compound 716340-Gs complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ...
著者Duan, J, Xu, P, Yang, J, Ji, Y, Zhang, H, Mao, C, Luan, X, Jiang, Y, Zhang, Y, Zhang, S, Xu, H.E.
登録日2023-01-14
公開日2023-03-29
最終更新日2023-04-05
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Mechanism of hormone and allosteric agonist mediated activation of follicle stimulating hormone receptor.
Nat Commun, 14, 2023
6PB1
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Cryo-EM structure of Urocortin 1-bound Corticotropin-releasing factor 2 receptor in complex with Gs protein and Nb35
分子名称: CHOLESTEROL, Corticotropin-releasing factor receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Ma, S, Shen, Q, Zhao, L.-H, Mao, C, Zhou, X.E, Shen, D.-D, de Waal, P.W, Bi, P, Li, C, Jiang, Y, Wang, M.-W, Sexton, P.M, Wootten, D, Melcher, K, Zhang, Y, Xu, H.E.
登録日2019-06-12
公開日2020-02-12
最終更新日2020-02-19
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Molecular Basis for Hormone Recognition and Activation of Corticotropin-Releasing Factor Receptors.
Mol.Cell, 77, 2020
6VX6
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bestrophin-2 Ca2+-bound state (250 nM Ca2+)
分子名称: Bestrophin, CALCIUM ION, CHLORIDE ION
著者Owji, A.P, Zhao, Q, Ji, C, Kittredge, A, Hopiavuori, A, Fu, Z, Ward, N, Clarke, O, Shen, Y, Zhang, Y, Hendrickson, W.A, Yang, T.
登録日2020-02-21
公開日2020-04-08
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural and functional characterization of the bestrophin-2 anion channel.
Nat.Struct.Mol.Biol., 27, 2020
6VX5
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bestrophin-2 Ca2+- unbound state (250 nM Ca2+)
分子名称: Bestrophin, CHLORIDE ION
著者Owji, A.P, Zhao, Q, Ji, C, Kittredge, A, Hopiavuori, A, Fu, Z, Ward, N, Clarke, O, Shen, Y, Zhang, Y, Hendrickson, W.A, Yang, T.
登録日2020-02-21
公開日2020-04-08
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献Structural and functional characterization of the bestrophin-2 anion channel.
Nat.Struct.Mol.Biol., 27, 2020
8IRV
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Dopamine Receptor D5R-Gs-Rotigotine complex
分子名称: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Xu, P, Huang, S, Zhuang, Y, Mao, C, Zhang, Y, Wang, Y, Li, H, Jiang, Y, Zhang, Y, Xu, H.E.
登録日2023-03-19
公開日2023-06-07
最終更新日2023-11-08
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural genomics of the human dopamine receptor system.
Cell Res., 33, 2023
8IRT
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Dopamine Receptor D3R-Gi-Rotigotine complex
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Xu, P, Huang, S, Zhuang, Y, Mao, C, Zhang, Y, Wang, Y, Li, H, Jiang, Y, Zhang, Y, Xu, H.E.
登録日2023-03-19
公開日2023-06-07
最終更新日2023-11-08
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural genomics of the human dopamine receptor system.
Cell Res., 33, 2023
8IRS
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Dopamine Receptor D2R-Gi-Rotigotine complex
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Xu, P, Huang, S, Zhuang, Y, Mao, C, Zhang, Y, Wang, Y, Li, H, Jiang, Y, Zhang, Y, Xu, H.E.
登録日2023-03-19
公開日2023-06-07
最終更新日2023-11-08
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural genomics of the human dopamine receptor system.
Cell Res., 33, 2023
6VVN
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F6 fused 4-OT wild type asymmetric trimer
分子名称: 4-oxalocrotonate tautomerase, GLYCEROL
著者Medellin, B.P, Whitman, C.P, Zhang, Y.J.
登録日2020-02-18
公開日2020-04-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Structural Basis for the Asymmetry of a 4-Oxalocrotonate Tautomerase Trimer.
Biochemistry, 59, 2020
8IRR
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Dopamine Receptor D1R-Gs-Rotigotine complex
分子名称: CHOLESTEROL, D(1A) dopamine receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Xu, P, Huang, S, Zhuang, Y, Mao, C, Zhang, Y, Wang, Y, Li, H, Jiang, Y, Zhang, Y, Xu, H.E.
登録日2023-03-19
公開日2023-06-21
最終更新日2023-11-08
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural genomics of the human dopamine receptor system.
Cell Res., 33, 2023
8IRU
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Dopamine Receptor D4R-Gi-Rotigotine complex
分子名称: CHOLESTEROL, D(4) dopamine receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Xu, P, Huang, S, Zhuang, Y, Mao, C, Zhang, Y, Wang, Y, Li, H, Jiang, Y, Zhang, Y, Xu, H.E.
登録日2023-03-19
公開日2023-06-21
最終更新日2023-11-08
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural genomics of the human dopamine receptor system.
Cell Res., 33, 2023
8W9Z
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The cryo-EM structure of the Nicotiana tabacum PEP-PAP
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta'', ...
著者Wu, X.X, Zhang, Y.
登録日2023-09-06
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cryo-EM structures of the plant plastid-encoded RNA polymerase.
Cell, 187, 2024
4QFL
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Crystal structure of dipeptide binding protein from pseudoalteromonas sp. SM9913 in complex with Ala-Phe
分子名称: ABC transporter periplasmic peptide-binding protein, ALANINE, GLYCEROL, ...
著者Li, C.Y, Zhang, Y.Z.
登録日2014-05-21
公開日2015-01-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.749 Å)
主引用文献Structural insights into the multispecific recognition of dipeptides of deep-sea gram-negative bacterium Pseudoalteromonas sp. strain SM9913
J. Bacteriol., 197, 2015
5C2Y
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Crystal structure of the Saccharomyces cerevisiae Rtr1 (regulator of transcription)
分子名称: GLYCEROL, RNA polymerase II subunit B1 CTD phosphatase RTR1, SULFATE ION, ...
著者Yogesha, S.D, Irani, S, Zhang, Y.J.
登録日2015-06-16
公開日2016-05-04
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of Saccharomyces cerevisiae Rtr1 reveals an active site for an atypical phosphatase.
Sci.Signal., 9, 2016
4QFO
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Crystal structure of dipeptide binding protein from pseudoalteromonas sp. SM9913 in complex with Met-Leu
分子名称: ABC transporter periplasmic peptide-binding protein, GLYCEROL, LEUCINE, ...
著者Li, C.Y, Zhang, Y.Z.
登録日2014-05-21
公開日2015-01-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.304 Å)
主引用文献Structural insights into the multispecific recognition of dipeptides of deep-sea gram-negative bacterium Pseudoalteromonas sp. strain SM9913
J. Bacteriol., 197, 2015
6PWX
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Cryo-EM structure of RbBP5 bound to the nucleosome
分子名称: DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Park, S.H, Ayoub, A, Lee, Y.T, Xu, J, Zhang, W, Zhang, B, Zhang, Y, Cianfrocco, M.A, Su, M, Dou, Y, Cho, U.
登録日2019-07-23
公開日2019-12-18
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryo-EM structure of the human MLL1 core complex bound to the nucleosome.
Nat Commun, 10, 2019
8I91
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ACE2-SIT1 complex bound with proline
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
著者Li, Y.N, Zhang, Y.Y, Shen, Y.P, Yan, R.H.
登録日2023-02-06
公開日2023-09-27
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural insight into the substrate recognition and transport mechanism of amino acid transporter complex ACE2-B 0 AT1 and ACE2-SIT1.
Cell Discov, 9, 2023
8I93
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ACE2-B0AT1 complex bound with methionine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
著者Li, Y.N, Zhang, Y.Y, Shen, Y.P, Yan, R.H.
登録日2023-02-06
公開日2023-09-27
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insight into the substrate recognition and transport mechanism of amino acid transporter complex ACE2-B 0 AT1 and ACE2-SIT1.
Cell Discov, 9, 2023
8I92
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ACE2-B0AT1 complex bound with glutamine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
著者Li, Y.N, Zhang, Y.Y, Shen, Y.P, Yan, R.H.
登録日2023-02-06
公開日2023-09-27
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural insight into the substrate recognition and transport mechanism of amino acid transporter complex ACE2-B 0 AT1 and ACE2-SIT1.
Cell Discov, 9, 2023
4QFN
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Crystal structure of dipeptide binding protein from pseudoalteromonas sp. SM9913 in complex with Gly-Glu
分子名称: ABC transporter periplasmic peptide-binding protein, GLUTAMIC ACID, GLYCINE
著者Li, C.Y, Zhang, Y.Z.
登録日2014-05-21
公開日2015-01-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.297 Å)
主引用文献Structural insights into the multispecific recognition of dipeptides of deep-sea gram-negative bacterium Pseudoalteromonas sp. strain SM9913
J. Bacteriol., 197, 2015
6PWV
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Cryo-EM structure of MLL1 core complex bound to the nucleosome
分子名称: DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Park, S.H, Ayoub, A, Lee, Y.T, Xu, J, Zhang, W, Zhang, B, Zhang, Y, Cianfrocco, M.A, Su, M, Dou, Y, Cho, U.
登録日2019-07-23
公開日2019-12-18
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (6.2 Å)
主引用文献Cryo-EM structure of the human MLL1 core complex bound to the nucleosome.
Nat Commun, 10, 2019
4QFP
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Crystal structure of dipeptide binding protein from pseudoalteromonas sp. SM9913 in complex with Val-Thr
分子名称: ABC transporter periplasmic peptide-binding protein, GLYCEROL, PHOSPHATE ION, ...
著者Li, C.Y, Zhang, Y.Z.
登録日2014-05-21
公開日2015-01-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.903 Å)
主引用文献Structural insights into the multispecific recognition of dipeptides of deep-sea gram-negative bacterium Pseudoalteromonas sp. strain SM9913
J. Bacteriol., 197, 2015
7TCL
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Crystal structure of P.IsnB complexed with tyrosine isonitrile
分子名称: (2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoic acid, MANGANESE (II) ION, SULFATE ION, ...
著者Kim, W, Zhang, Y.
登録日2021-12-26
公開日2022-08-31
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Elucidation of divergent desaturation pathways in the formation of vinyl isonitrile and isocyanoacrylate.
Nat Commun, 13, 2022
8WM0
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Crystal structure of TNIK-thiopeptide wTP3 complex
分子名称: ADENOSINE, THIOPEPTIDE wTP3, TRAF2 and NCK-interacting protein kinase
著者Hamada, K, Kobayashi, S, Vinogradov, A.A, Zhang, Y, Goto, Y, Suga, H, Ogata, K, Sengoku, T.
登録日2023-10-01
公開日2024-03-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A Compact Reprogrammed Genetic Code for De Novo Discovery of Proteolytically Stable Thiopeptides.
J.Am.Chem.Soc., 2024
8IK2
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RhlA exhibits dual thioesterase and acyltransferase activities during rhamnolipid biosynthesis
分子名称: (3~{S})-3-oxidanyldecanoic acid, 3-(3-hydroxydecanoyloxy)decanoate synthase
著者Tang, T, Fu, L.H, Xie, W.H, Luo, Y.Z, Zhang, Y.T, Si, T.
登録日2023-02-28
公開日2023-11-01
実験手法X-RAY DIFFRACTION (2.151 Å)
主引用文献RhlA Exhibits Dual Thioesterase and Acyltransferase Activities during Rhamnolipid Biosynthesis
Acs Catalysis, 13, 2023
6J76
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Structure of 3,6-anhydro-L-galactose Dehydrogenase in Complex with NAP
分子名称: Aldehyde dehydrogenase A, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Li, P.Y, Wang, Y, Chen, X.L, Zhang, Y.Z.
登録日2019-01-17
公開日2020-01-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.368 Å)
主引用文献3,6-Anhydro-L-Galactose Dehydrogenase VvAHGD is a Member of a New Aldehyde Dehydrogenase Family and Catalyzes by a Novel Mechanism with Conformational Switch of Two Catalytic Residues Cysteine 282 and Glutamate 248.
J.Mol.Biol., 432, 2020

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件を2024-06-19に公開中

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