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PDB: 1659 件

8IHM
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Eaf3 CHD domain bound to the nucleosome
分子名称: Chromatin modification-related protein EAF3, DNA (164-MER), DNA (165-MER), ...
著者Zhang, Y, Gang, C.
登録日2023-02-23
公開日2024-03-20
実験手法ELECTRON MICROSCOPY (3.58 Å)
主引用文献Structural basis for nucleosome binding and catalysis by the yeast Rpd3S/HDAC holoenzyme.
Cell Res., 33, 2023
8IHN
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BU of 8ihn by Molmil
Cryo-EM structure of the Rpd3S core complex
分子名称: CALCIUM ION, Chromatin modification-related protein EAF3, Histone H3, ...
著者Zhang, Y, Gang, C.
登録日2023-02-23
公開日2024-03-20
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Structural basis for nucleosome binding and catalysis by the yeast Rpd3S/HDAC holoenzyme.
Cell Res., 33, 2023
8IHT
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Rpd3S bound to the nucleosome
分子名称: CALCIUM ION, Chromatin modification-related protein EAF3, DNA (164-MER), ...
著者Zhang, Y, Gang, C.
登録日2023-02-23
公開日2024-03-20
実験手法ELECTRON MICROSCOPY (3.72 Å)
主引用文献Structural basis for nucleosome binding and catalysis by the yeast Rpd3S/HDAC holoenzyme.
Cell Res., 33, 2023
6JJI
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BU of 6jji by Molmil
Crystal structure of a two-quartet RNA parallel G-quadruplex complexed with the porphyrin TMPyP4 (1:1)
分子名称: (1Z,4Z,9Z,15Z)-5,10,15,20-tetrakis(1-methylpyridin-1-ium-4-yl)-21,23-dihydroporphyrin, POTASSIUM ION, RNA (5'-R(*GP*GP*CP*UP*CP*GP*GP*CP*GP*GP*CP*GP*GP*A)-3')
著者Zhang, Y.S, Parkinson, G.N, Wei, D.G.
登録日2019-02-25
公開日2020-02-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Native de novo structural determinations of non-canonical nucleic acid motifs by X-ray crystallography at long wavelengths.
Nucleic Acids Res., 48, 2020
6JJH
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BU of 6jjh by Molmil
Crystal structure of a two-quartet RNA parallel G-quadruplex complexed with the porphyrin TMPyP4
分子名称: (1Z,4Z,9Z,15Z)-5,10,15,20-tetrakis(1-methylpyridin-1-ium-4-yl)-21,23-dihydroporphyrin, POTASSIUM ION, RNA (5'-R(*GP*GP*CP*UP*CP*GP*GP*CP*GP*GP*CP*GP*GP*A)-3')
著者Zhang, Y.S, EI Omari, K, Duman, R, Wagner, A, Parkinson, G.N, Wei, D.G.
登録日2019-02-25
公開日2020-02-26
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Native de novo structural determinations of non-canonical nucleic acid motifs by X-ray crystallography at long wavelengths.
Nucleic Acids Res., 48, 2020
1FKC
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BU of 1fkc by Molmil
HUMAN PRION PROTEIN (MUTANT E200K) FRAGMENT 90-231
分子名称: PRION PROTEIN
著者Zhang, Y, Swietnicki, W, Zagorski, M.G, Surewicz, W.K, Soennichsen, F.D.
登録日2000-08-09
公開日2000-09-21
最終更新日2018-03-14
実験手法SOLUTION NMR
主引用文献Solution structure of the E200K variant of human prion protein. Implications for the mechanism of pathogenesis in familial prion diseases.
J.Biol.Chem., 275, 2000
1FO7
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BU of 1fo7 by Molmil
HUMAN PRION PROTEIN MUTANT E200K FRAGMENT 90-231
分子名称: PRION PROTEIN
著者Zhang, Y, Swietnicki, W, Zagorski, M.G, Surewicz, W.K, Soennichsen, F.D.
登録日2000-08-25
公開日2000-09-21
最終更新日2018-03-14
実験手法SOLUTION NMR
主引用文献Solution structure of the E200K variant of human prion protein. Implications for the mechanism of pathogenesis in familial prion diseases.
J.Biol.Chem., 275, 2000
4FK3
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BU of 4fk3 by Molmil
B-Raf Kinase V600E Oncogenic Mutant in Complex with PLX3203
分子名称: N-{2,4-difluoro-3-[(5-pyridin-3-yl-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]phenyl}ethanesulfonamide, Serine/threonine-protein kinase B-raf
著者Zhang, Y, Wang, W, Zhang, K.Y.J.
登録日2012-06-12
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity.
Proc.Natl.Acad.Sci.USA, 105, 2008
5T0X
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BU of 5t0x by Molmil
Solution NMR-derived structure of calmodulin bound with ER alpha peptides
分子名称: CALCIUM ION, Calmodulin, Estrogen receptor peptide
著者Zhang, Y, Ames, J.B.
登録日2016-08-16
公開日2017-02-15
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution NMR-derived structure of calmodulin bound with ER alpha peptides
To Be Published
6LTS
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BU of 6lts by Molmil
Crystal structure of Thermus thermophilus transcription initiation complex comprising a truncated sigma finger
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Zhang, Y, Ebright, R.H.
登録日2020-01-23
公開日2020-03-11
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription.
Proc.Natl.Acad.Sci.USA, 117, 2020
4H6P
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BU of 4h6p by Molmil
Crystal structure of a putative chromate reductase from Gluconacetobacter hansenii, Gh-ChrR, containing a R101A substitution.
分子名称: Chromate reductase, FLAVIN MONONUCLEOTIDE
著者Zhang, Y, Robinson, H, Buchko, G.W.
登録日2012-09-19
公開日2012-10-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.556 Å)
主引用文献Mechanistic insights of chromate and uranyl reduction by the NADPH-dependent FMN reductase, ChrR, from Gluconacetobacter hansenii
To be Published
3V7T
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BU of 3v7t by Molmil
Crystal Structure of Human Beta-Tryptase Complexed with a Synthetic Inhibitor with a Tropanylamide Scaffold
分子名称: CARBONATE ION, TPSB2 protein, {(3-exo)-3-[5-(aminomethyl)-2-fluorophenyl]-8-azabicyclo[3.2.1]oct-8-yl}(4-bromo-3-methyl-5-propoxythiophen-2-yl)methanone
著者Zhang, Y, Colonna, C, Michot, N.
登録日2011-12-22
公開日2012-03-14
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献A beta-tryptase inhibitor with a tropanylamide scaffold to improve in vitro stability and to lower hERG channel binding affinity
Bioorg.Med.Chem.Lett., 22, 2012
3OGG
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BU of 3ogg by Molmil
Crystal structure of the receptor binding domain of botulinum neurotoxin D
分子名称: Botulinum neurotoxin type D
著者Zhang, Y, Gao, X, Qin, L, Buchko, G.W, Robinson, H, Varnum, S.M.
登録日2010-08-16
公開日2010-09-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.651 Å)
主引用文献Structural analysis of the receptor binding domain of botulinum neurotoxin serotype D.
Biochem.Biophys.Res.Commun., 401, 2010
7EU7
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BU of 7eu7 by Molmil
Structure of the human GluN1-GluN2A NMDA receptor in complex with S-ketamine, glycine and glutamate
分子名称: (2~{S})-2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ...
著者Zhang, Y, Zhang, T, Zhu, S.
登録日2021-05-16
公開日2021-08-04
最終更新日2022-10-26
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis of ketamine action on human NMDA receptors.
Nature, 596, 2021
4ES7
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BU of 4es7 by Molmil
crystal structure of protein HC from Homo sapiens at 2 angstrom
分子名称: DI(HYDROXYETHYL)ETHER, Protein AMBP
著者Zhang, Y.L, Gao, Z.Q, Wang, D.Q, Dong, Y.H.
登録日2012-04-22
公開日2013-04-24
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献crystal structure of protein HC from Home sapiens at 2 angstrom
To be Published
4G7Z
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BU of 4g7z by Molmil
Crystal structure of Thermus thermophilus transcription initiation complex containing 5-BrU at template-strand position +1
分子名称: 5'-D(*CP*CP*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*(BRU)P*CP*GP*AP*GP*GP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', DNA-directed RNA polymerase subunit alpha, ...
著者Zhang, Y, Ebright, R.H.
登録日2012-07-20
公開日2012-10-31
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.815 Å)
主引用文献Structural basis of transcription initiation.
Science, 338, 2012
4HS4
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BU of 4hs4 by Molmil
Crystal structure of a putative chromate reductase from Gluconacetobacter hansenii, Gh-ChrR, containing a Y129N substitution.
分子名称: Chromate reductase, FLAVIN MONONUCLEOTIDE
著者Zhang, Y, Robinson, H, Buchko, G.W.
登録日2012-10-29
公開日2012-12-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Mechanistic insights of chromate and uranyl reduction by the NADPH-dependent FMN reductase, ChrR, from Gluconacetobacter hansenii
To be Published
3RY0
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BU of 3ry0 by Molmil
Crystal structure of TomN, a 4-Oxalocrotonate Tautomerase homologue in Tomaymycin biosynthetic pathway
分子名称: Putative tautomerase
著者Zhang, Y, Yan, W.P, Li, W.Z, Whitman, C.P.
登録日2011-05-10
公開日2011-08-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Kinetic, Crystallographic, and Mechanistic Characterization of TomN: Elucidation of a Function for a 4-Oxalocrotonate Tautomerase Homologue in the Tomaymycin Biosynthetic Pathway.
Biochemistry, 50, 2011
2LD5
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BU of 2ld5 by Molmil
Solution NMR-derived complex structure of Hoxa13 DNA binding domain bound to DNA
分子名称: DNA (5'-D(*CP*AP*AP*AP*TP*AP*AP*AP*AP*TP*C)-3'), DNA (5'-D(P*GP*AP*TP*TP*TP*TP*AP*TP*TP*TP*G)-3'), Homeobox protein Hox-A13
著者Zhang, Y.
登録日2011-05-14
公開日2011-08-10
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural basis for sequence specific DNA binding and protein dimerization of HOXA13.
Plos One, 6, 2011
2LLO
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BU of 2llo by Molmil
Solution NMR-derived structure of calmodulin N-lobe bound with ER alpha peptide
分子名称: CALCIUM ION, Calmodulin, Estrogen receptor
著者Zhang, Y.
登録日2011-11-15
公開日2012-02-01
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural basis for Ca2+-induced activation and dimerization of estrogen receptor alpha by calmodulin.
J.Biol.Chem., 287, 2012
2L80
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BU of 2l80 by Molmil
Solution Structure of the Zinc Finger Domain of USP13
分子名称: Ubiquitin carboxyl-terminal hydrolase 13, ZINC ION
著者Zhang, Y, Zhou, C, Zhou, Z, Song, A, Hu, H.
登録日2010-12-28
公開日2011-12-14
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Biochemical Characterization of the Ubiquitin Receptors in USP13 Reveals Different Catalytic Activation of Deubiquitination from Its Analogue USP5
To be Published
6JJF
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BU of 6jjf by Molmil
Crystal structure of a two-quartet DNA mixed-parallel/antiparallel G-quadruplex
分子名称: COBALT HEXAMMINE(III), DNA (5'-D(*GP*GP*CP*TP*CP*GP*GP*CP*GP*GP*CP*GP*GP*A)-3'), POTASSIUM ION, ...
著者Zhang, Y.S, EI Omari, K, Duman, R, Wagner, A, Parkinson, G.N, Wei, D.G.
登録日2019-02-25
公開日2020-02-26
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Native de novo structural determinations of non-canonical nucleic acid motifs by X-ray crystallography at long wavelengths.
Nucleic Acids Res., 48, 2020
2LLQ
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BU of 2llq by Molmil
Solution nmr-derived structure of calmodulin c-lobe bound with er alpha peptide
分子名称: CALCIUM ION, Calmodulin, Estrogen receptor
著者Zhang, Y.
登録日2011-11-15
公開日2012-02-01
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural basis for Ca2+-induced activation and dimerization of estrogen receptor alpha by calmodulin.
J.Biol.Chem., 287, 2012
2LRJ
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BU of 2lrj by Molmil
NMR solution structure of staphyloxanthin biosynthesis protein
分子名称: Staphyloxanthin biosynthesis protein, putative
著者Zhang, Y, Winsor, J, Anderson, W, Radhakrishnan, I, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2012-04-03
公開日2012-04-18
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of a putative S. aureus enzyme involved in the biosynthesis of staphyloxanthin
To be Published
2LBC
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BU of 2lbc by Molmil
solution structure of tandem UBA of USP13
分子名称: Ubiquitin carboxyl-terminal hydrolase 13
著者Zhang, Y, Zhou, C, Zhou, Z, Song, A, Hu, H.
登録日2011-03-29
公開日2012-03-07
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Domain Analysis Reveals That a Deubiquitinating Enzyme USP13 Performs Non-Activating Catalysis for Lys63-Linked Polyubiquitin.
Plos One, 6, 2011

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件を2024-07-24に公開中

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