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PDB: 1650 件

5YGC
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Crystal structure of Drosophila melanogaster Papi extended Tudor domain
分子名称: GH18329p
著者Zhang, Y.H, Huang, Y.
登録日2017-09-22
公開日2018-03-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural insights into the sequence-specific recognition of Piwi byDrosophilaPapi
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7ESD
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Mature Donggang virus
分子名称: Genome polyprotein
著者Zhang, Y, Liang, D.
登録日2021-05-10
公開日2022-05-18
最終更新日2022-06-29
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Replication is the key barrier during the dual-host adaptation of mosquito-borne flaviviruses.
Proc.Natl.Acad.Sci.USA, 119, 2022
7XJR
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BU of 7xjr by Molmil
MLXase AlXyn26A
分子名称: AlXyn26A
著者Zhang, Y.Z, Chen, X.L, Zhao, F, Yu, C.M.
登録日2022-04-18
公開日2023-04-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A novel class of xylanases specifically degrade marine red algal beta 1,3/1,4-mixed-linkage xylan.
J.Biol.Chem., 299, 2023
7F3L
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Crystal structure of human YBX2 CSD in complex with m5C RNA in space group P62
分子名称: RNA (5'-R(P*CP*AP*UP*(5MC))-3'), Y-box-binding protein 2
著者Zhang, Y, Huang, Y.
登録日2021-06-16
公開日2022-06-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Crystal structure of human YBX2 CSD in complex with m5C RNA in space group P62
To Be Published
1YFW
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Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase from Ralstonia metallidurans complexed with 4-chloro-3-hydroxyanthranilic acid and O2
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-hydroxyanthranilate-3,4-dioxygenase, 4-CHLORO-3-HYDROXYANTHRANILIC ACID, ...
著者Zhang, Y, Colabroy, K.L, Begley, T.P, Ealick, S.E.
登録日2005-01-04
公開日2005-05-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Studies on 3-Hydroxyanthranilate-3,4-dioxygenase: The Catalytic Mechanism of a Complex Oxidation Involved in NAD Biosynthesis.
Biochemistry, 44, 2005
1YFX
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Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase from Ralstonia metallidurans complexed with 4-chloro-3-hydroxyanthranilic acid and NO
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-hydroxyanthranilate-3,4-dioxygenase, 4-CHLORO-3-HYDROXYANTHRANILIC ACID, ...
著者Zhang, Y, Colabroy, K.L, Begley, T.P, Ealick, S.E.
登録日2005-01-04
公開日2005-05-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Studies on 3-Hydroxyanthranilate-3,4-dioxygenase: The Catalytic Mechanism of a Complex Oxidation Involved in NAD Biosynthesis.
Biochemistry, 44, 2005
4OIP
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BU of 4oip by Molmil
Crystal structure of Thermus thermophilus transcription initiation complex soaked with GE23077, ATP, and CMPcPP
分子名称: (2Z)-2-methylbut-2-enoic acid, 5'-D(*CP*CP*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', ...
著者Zhang, Y, Ebright, R.H, Arnold, E.
登録日2014-01-20
公開日2014-05-07
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides.
Elife, 3, 2014
4Z69
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Human serum albumin complexed with palmitic acid and diclofenac
分子名称: 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID, PALMITIC ACID, PENTADECANOIC ACID, ...
著者Zhang, Y, Yang, F.
登録日2015-04-04
公開日2016-01-27
実験手法X-RAY DIFFRACTION (2.187 Å)
主引用文献Structural basis of non-steroidal anti-inflammatory drug diclofenac binding to human serum albumin.
Chem.Biol.Drug Des., 86, 2015
6J2R
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Crystal structure of Striga hermonthica HTL8 (ShHTL8)
分子名称: GLYCEROL, Hyposensitive to light 8
著者Zhang, Y.Y, Xi, Z.
登録日2019-01-02
公開日2020-01-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structure and biochemical characterization of Striga hermonthica HYPO-SENSITIVE TO LIGHT 8 (ShHTL8) in strigolactone signaling pathway.
Biochem.Biophys.Res.Commun., 523, 2020
3PWM
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HIV-1 Protease Mutant L76V with Darunavir
分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, ACETATE ION, CHLORIDE ION, ...
著者Zhang, Y, Weber, I.T.
登録日2010-12-08
公開日2011-04-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献The L76V Drug Resistance Mutation Decreases the Dimer Stability and Rate of Autoprocessing of HIV-1 Protease by Reducing Internal Hydrophobic Contacts.
Biochemistry, 50, 2011
4OIQ
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Crystal structure of Thermus thermophilus transcription initiation complex soaked with GE23077 and rifampicin
分子名称: (2Z)-2-methylbut-2-enoic acid, 5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', ...
著者Zhang, Y, Ebright, R.H, Arnold, E.
登録日2014-01-20
公開日2014-05-07
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.624 Å)
主引用文献GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides.
Elife, 3, 2014
3PY3
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BU of 3py3 by Molmil
Crystal structure of phosphorylated p38alpha MAP kinase
分子名称: Mitogen-activated protein kinase 14
著者Zhang, Y.Y, Wu, J.W, Wang, Z.X.
登録日2010-12-11
公開日2011-03-16
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Mitogen-activated Protein Kinase (MAPK) Phosphatase 3-mediated Cross-talk between MAPKs ERK2 and p38{alpha}.
J.Biol.Chem., 286, 2011
4OIO
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BU of 4oio by Molmil
Crystal structure of Thermus thermophilus pre-insertion substrate complex for de novo transcription initiation
分子名称: 5'-D(*CP*CP*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, ...
著者Zhang, Y, Ebright, R.H, Arnold, E.
登録日2014-01-20
公開日2014-05-07
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides.
Elife, 3, 2014
1YFU
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BU of 1yfu by Molmil
Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase from Ralstonia metallidurans
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-hydroxyanthranilate-3,4-dioxygenase, CHLORIDE ION, ...
著者Zhang, Y, Colabroy, K.L, Begley, T.P, Ealick, S.E.
登録日2005-01-04
公開日2005-05-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Studies on 3-Hydroxyanthranilate-3,4-dioxygenase: The Catalytic Mechanism of a Complex Oxidation Involved in NAD Biosynthesis.
Biochemistry, 44, 2005
2A8Y
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Crystal structure of 5'-deoxy-5'methylthioadenosine phosphorylase complexed with 5'-deoxy-5'methylthioadenosine and sulfate
分子名称: 5'-DEOXY-5'-METHYLTHIOADENOSINE, 5'-methylthioadenosine phosphorylase (mtaP), SULFATE ION
著者Zhang, Y, Porcelli, M, Cacciapuoti, G, Ealick, S.E.
登録日2005-07-10
公開日2006-03-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献The crystal structure of 5'-deoxy-5'-methylthioadenosine phosphorylase II from Sulfolobus solfataricus, a thermophilic enzyme stabilized by intramolecular disulfide bonds.
J.Mol.Biol., 357, 2006
7DK8
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BU of 7dk8 by Molmil
Crystal structure of OsGH3-8 with AMP
分子名称: ADENOSINE MONOPHOSPHATE, Probable indole-3-acetic acid-amido synthetase GH3.8
著者Zhang, Y.K, Xu, G.L, Ming, Z.H.
登録日2020-11-23
公開日2020-12-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Crystal structure of the acyl acid amido synthetase GH3-8 from Oryza sativa.
Biochem.Biophys.Res.Commun., 534, 2021
3PWR
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BU of 3pwr by Molmil
HIV-1 Protease Mutant L76V complexed with Saquinavir
分子名称: (2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, CHLORIDE ION, GLYCEROL, ...
著者Zhang, Y, Weber, I.T.
登録日2010-12-08
公開日2011-04-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献The L76V Drug Resistance Mutation Decreases the Dimer Stability and Rate of Autoprocessing of HIV-1 Protease by Reducing Internal Hydrophobic Contacts.
Biochemistry, 50, 2011
4HBG
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BU of 4hbg by Molmil
Crystal structure of Saccharomyces cerevisiae 3 oxoacyl-[acyl carrier protein]-reductase complexed with NADPH (form2)
分子名称: 3-oxoacyl-[acyl-carrier-protein] reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Zhang, Y.J, Gao, Y.X, Teng, M.K.
登録日2012-09-27
公開日2013-10-30
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Crystal structure of yeast mitochondria 3-Oxoacyl-ACP Reductase OAR1
To be Published
4NPT
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Crystal Structure of HIV-1 Protease Multiple Mutant P51 Complexed with Darunavir
分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, GLYCEROL, Protease
著者Zhang, Y, Weber, I.T.
登録日2013-11-22
公開日2014-10-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Structures of darunavir-resistant HIV-1 protease mutant reveal atypical binding of darunavir to wide open flaps.
Acs Chem.Biol., 9, 2014
2A7Q
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Crystal structure of human dCK complexed with clofarabine and ADP
分子名称: 2-CHLORO-9-(2-DEOXY-2-FLUORO-B -D-ARABINOFURANOSYL)-9H-PURIN-6-AMINE, ADENOSINE-5'-DIPHOSPHATE, Deoxycytidine kinase, ...
著者Zhang, Y, Secrist III, J.A, Ealick, S.E.
登録日2005-07-05
公開日2006-01-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献The structure of human deoxycytidine kinase in complex with clofarabine reveals key interactions for prodrug activation.
Acta Crystallogr.,Sect.D, 62, 2006
4L1I
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BU of 4l1i by Molmil
Crystal structure of EGFP-based Calcium Sensor CatchER complexed with Ca
分子名称: CALCIUM ION, EGFP-based Calcium Sensor CatchER
著者Zhang, Y, Weber, I.T.
登録日2013-06-03
公開日2013-12-11
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structural basis for a hand-like site in the calcium sensor CatchER with fast kinetics.
Acta Crystallogr.,Sect.D, 69, 2013
1YFY
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BU of 1yfy by Molmil
Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase from Ralstonia metallidurans complexed with 3-hydroxyanthranilic acid
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-HYDROXYANTHRANILIC ACID, 3-hydroxyanthranilate-3,4-dioxygenase, ...
著者Zhang, Y, Colabroy, K.L, Begley, T.P, Ealick, S.E.
登録日2005-01-04
公開日2005-05-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural Studies on 3-Hydroxyanthranilate-3,4-dioxygenase: The Catalytic Mechanism of a Complex Oxidation Involved in NAD Biosynthesis.
Biochemistry, 44, 2005
4L12
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Crystal structure of EGFP-based Calcium Sensor CatchER complexed with Gd
分子名称: EGFP-based Calcium Sensor CatchER, GADOLINIUM ATOM
著者Zhang, Y, Weber, I.T.
登録日2013-06-01
公開日2013-12-11
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Structural basis for a hand-like site in the calcium sensor CatchER with fast kinetics.
Acta Crystallogr.,Sect.D, 69, 2013
1VZT
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BU of 1vzt by Molmil
ROLES OF INDIVIDUAL RESIDUES OF ALPHA-1,3 GALACTOSYLTRANSFERASES IN SUBSTRATE BINDING AND CATALYSIS
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MANGANESE (II) ION, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, ...
著者Zhang, Y, Swaminathan, G.J, Deshpande, A, Natesh, R, Xie, X, Acharya, K.R, Brew, K.
登録日2004-05-26
公開日2005-05-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Roles of Individual Enzyme-Substrate Interactions by Alpha-1,3-Galactosyltransferase in Catalysis and Specificity.
Biochemistry, 42, 2003
2R85
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Crystal structure of PurP from Pyrococcus furiosus complexed with AMP
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ...
著者Zhang, Y, White, R.H, Ealick, S.E.
登録日2007-09-10
公開日2007-12-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure and function of 5-formaminoimidazole-4-carboxamide ribonucleotide synthetase from Methanocaldococcus jannaschii.
Biochemistry, 47, 2008

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