7W5B
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![BU of 7w5b by Molmil](/molmil-images/mine/7w5b) | The cryo-EM structure of human C* complex | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | Authors: | Zhan, X, Lu, Y, Shi, Y. | Deposit date: | 2021-11-29 | Release date: | 2022-06-22 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022
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7W5A
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![BU of 7w5a by Molmil](/molmil-images/mine/7w5a) | The cryo-EM structure of human pre-C*-II complex | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | Authors: | Zhan, X, Lu, Y, Shi, Y. | Deposit date: | 2021-11-29 | Release date: | 2022-06-22 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022
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7W59
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![BU of 7w59 by Molmil](/molmil-images/mine/7w59) | The cryo-EM structure of human pre-C*-I complex | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | Authors: | Zhan, X, Lu, Y, Shi, Y. | Deposit date: | 2021-11-29 | Release date: | 2022-06-22 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022
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8JB5
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![BU of 8jb5 by Molmil](/molmil-images/mine/8jb5) | |
4O68
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![BU of 4o68 by Molmil](/molmil-images/mine/4o68) | Structure of human cyclic GMP-AMP synthase (cGAS) | Descriptor: | Cyclic GMP-AMP synthase, ZINC ION | Authors: | Zhang, X, Chen, Z, Zhang, X.W, Chen, Z.J. | Deposit date: | 2013-12-20 | Release date: | 2014-02-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.436 Å) | Cite: | The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop. Cell Rep, 6, 2014
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4O67
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![BU of 4o67 by Molmil](/molmil-images/mine/4o67) | Human cyclic GMP-AMP synthase (cGAS) in complex with GAMP | Descriptor: | Cyclic GMP-AMP synthase, ZINC ION, cGAMP | Authors: | Zhang, X, Chen, Z, Zhang, X.W, Chen, Z.J. | Deposit date: | 2013-12-20 | Release date: | 2014-02-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.444 Å) | Cite: | The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop. Cell Rep, 6, 2014
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4O69
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![BU of 4o69 by Molmil](/molmil-images/mine/4o69) | Human cyclic GMP-AMP synthase (cGAS) in complex with sulfate ion | Descriptor: | Cyclic GMP-AMP synthase, SULFATE ION, ZINC ION | Authors: | Zhang, X, Chen, Z, Zhang, X.W, Chen, Z.J. | Deposit date: | 2013-12-20 | Release date: | 2014-02-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.252 Å) | Cite: | The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop. Cell Rep, 6, 2014
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4O6A
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![BU of 4o6a by Molmil](/molmil-images/mine/4o6a) | Mouse cyclic GMP-AMP synthase (cGAS) in complex with DNA | Descriptor: | Cyclic GMP-AMP synthase, DNA1, DNA2, ... | Authors: | Zhang, X, Chen, Z, Zhang, X.W, Chen, Z.J. | Deposit date: | 2013-12-20 | Release date: | 2014-02-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.859 Å) | Cite: | The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop. Cell Rep, 6, 2014
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8T3V
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![BU of 8t3v by Molmil](/molmil-images/mine/8t3v) | Cryo-EM structure of the DHA bound FFA1-Gq complex | Descriptor: | CHOLESTEROL, DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID, Free fatty acid receptor 1, ... | Authors: | Zhang, X, Tikhonova, I, Milligan, G, Zhang, C. | Deposit date: | 2023-06-07 | Release date: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (3.39 Å) | Cite: | Structural basis for the ligand recognition and signaling of free fatty acid receptors. Sci Adv, 10, 2024
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5VJJ
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![BU of 5vjj by Molmil](/molmil-images/mine/5vjj) | Crystal structure of the flax-rust effector AvrP | Descriptor: | Avirulence protein AvrP123, ZINC ION | Authors: | Zhang, X, Ericsson, D.J, Williams, S.J, Kobe, B. | Deposit date: | 2017-04-19 | Release date: | 2017-08-30 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | Crystal structure of the Melampsora lini effector AvrP reveals insights into a possible nuclear function and recognition by the flax disease resistance protein P. Mol. Plant Pathol., 19, 2018
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4O9L
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![BU of 4o9l by Molmil](/molmil-images/mine/4o9l) | |
2Y3A
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![BU of 2y3a by Molmil](/molmil-images/mine/2y3a) | Crystal structure of p110beta in complex with icSH2 of p85beta and the drug GDC-0941 | Descriptor: | 2-(1H-indazol-4-yl)-6-{[4-(methylsulfonyl)piperazin-1-yl]methyl}-4-morpholin-4-yl-thieno[3,2-d]pyrimidine, PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT BETA, PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT BETA ISOFORM | Authors: | Zhang, X, Vadas, O, Perisic, O, Williams, R.L. | Deposit date: | 2010-12-20 | Release date: | 2011-03-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structure of Lipid Kinase P110Beta-P85Beta Elucidates an Unusual Sh2-Domain-Mediated Inhibitory Mechanism. Mol.Cell, 41, 2011
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5KQA
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![BU of 5kqa by Molmil](/molmil-images/mine/5kqa) | Crystal structure of buckwheat glutaredoxin-glutathione complex | Descriptor: | GLUTATHIONE, Glutaredoxin-glutathione complex | Authors: | Zhang, X, Wang, W, Zhao, Y, Wang, Z, Wang, H. | Deposit date: | 2016-07-06 | Release date: | 2017-07-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural insights into the binding of buckwheat glutaredoxin with GSH and regulation of its catalytic activity J. Inorg. Biochem., 173, 2017
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7Y56
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![BU of 7y56 by Molmil](/molmil-images/mine/7y56) | |
7Y57
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![BU of 7y57 by Molmil](/molmil-images/mine/7y57) | |
5K3J
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![BU of 5k3j by Molmil](/molmil-images/mine/5k3j) | Crystals structure of Acyl-CoA oxidase-2 in Caenorhabditis elegans bound with FAD, ascaroside-CoA, and ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Acyl-coenzyme A oxidase, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Zhang, X, Li, K, Jones, R.A, Bruner, S.D, Butcher, R.A. | Deposit date: | 2016-05-19 | Release date: | 2016-08-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Structural characterization of acyl-CoA oxidases reveals a direct link between pheromone biosynthesis and metabolic state in Caenorhabditis elegans. Proc.Natl.Acad.Sci.USA, 113, 2016
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7XT1
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![BU of 7xt1 by Molmil](/molmil-images/mine/7xt1) | |
1L71
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![BU of 1l71 by Molmil](/molmil-images/mine/1l71) | |
1L69
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![BU of 1l69 by Molmil](/molmil-images/mine/1l69) | |
1L74
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![BU of 1l74 by Molmil](/molmil-images/mine/1l74) | |
1L73
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![BU of 1l73 by Molmil](/molmil-images/mine/1l73) | |
1L72
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1L70
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1L75
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![BU of 1l75 by Molmil](/molmil-images/mine/1l75) | |
1HQK
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![BU of 1hqk by Molmil](/molmil-images/mine/1hqk) | CRYSTAL STRUCTURE ANALYSIS OF LUMAZINE SYNTHASE FROM AQUIFEX AEOLICUS | Descriptor: | 6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE | Authors: | Zhang, X, Meining, W, Fischer, M, Bacher, A, Ladenstein, R. | Deposit date: | 2000-12-18 | Release date: | 2001-12-18 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | X-ray structure analysis and crystallographic refinement of lumazine synthase from the hyperthermophile Aquifex aeolicus at 1.6 A resolution: determinants of thermostability revealed from structural comparisons. J.Mol.Biol., 306, 2001
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