8T3O
 
 | | Cryo-EM structure of the TUG-891 bound FFA4-Gq complex | | 分子名称: | (2R)-1-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, 3-{4-[(4-fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]phenyl}propanoic acid, Free fatty acid receptor 4, ... | | 著者 | Zhang, X, Tikhonova, I, Milligan, G, Zhang, C. | | 登録日 | 2023-06-07 | | 公開日 | 2024-01-17 | | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | | 主引用文献 | Structural basis for the ligand recognition and signaling of free fatty acid receptors.
Sci Adv, 10, 2024
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8T3Q
 | | Cryo-EM structure of the DHA bound FFA4-Gq complex | | 分子名称: | DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID, Free fatty acid receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Zhang, X, Tikhonova, I, Milligan, G, Zhang, C. | | 登録日 | 2023-06-07 | | 公開日 | 2024-01-24 | | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | | 主引用文献 | Structural basis for the ligand recognition and signaling of free fatty acid receptors.
Sci Adv, 10, 2024
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4Q2M
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4Q2L
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4GJE
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6LSV
 | | Crystal structure of JOX2 in complex with 2OG, Fe, and JA | | 分子名称: | 2-OXOGLUTARIC ACID, FE (III) ION, Probable 2-oxoglutarate-dependent dioxygenase At5g05600, ... | | 著者 | Zhang, X, Wang, D, Liu, J. | | 登録日 | 2020-01-20 | | 公開日 | 2021-02-10 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.651 Å) | | 主引用文献 | Structure-guided analysis of Arabidopsis JASMONATE-INDUCED OXYGENASE (JOX) 2 reveals key residues for recognition of jasmonic acid substrate by plant JOXs.
Mol Plant, 14, 2021
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6JK8
 | | Cryo-EM structure of the full-length human IGF-1R in complex with insulin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin, ... | | 著者 | Zhang, X, Yu, D, Wang, T. | | 登録日 | 2019-02-27 | | 公開日 | 2020-03-04 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | | 主引用文献 | Visualization of Ligand-Bound Ectodomain Assembly in the Full-Length Human IGF-1 Receptor by Cryo-EM Single-Particle Analysis.
Structure, 28, 2020
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4GJF
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4GJG
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8JSD
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4N6E
 | | Crystal structure of Amycolatopsis orientalis BexX/CysO complex | | 分子名称: | Putative thiosugar synthase, SULFATE ION, ThiS/MoaD family protein | | 著者 | Zhang, X, Zhang, Y, Kinsland, C, Sasaki, E, Sun, H.G, Lu, M.J, Liu, T, Ou, A, Li, J, Chen, Y, Liu, H, Ealick, S.E. | | 登録日 | 2013-10-11 | | 公開日 | 2014-05-14 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Co-opting sulphur-carrier proteins from primary metabolic pathways for 2-thiosugar biosynthesis.
Nature, 509, 2014
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5ZCX
 | | Structure of T20/N39 | | 分子名称: | Envelope glycoprotein, Envelope glycoprotein gp160 | | 著者 | Zhang, X.J, Ding, X.H. | | 登録日 | 2018-02-21 | | 公開日 | 2018-10-10 | | 最終更新日 | 2018-12-19 | | 実験手法 | X-RAY DIFFRACTION (2.299 Å) | | 主引用文献 | Structural and functional characterization of HIV-1 cell fusion inhibitor T20.
AIDS, 33, 2019
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5Y14
 | | Crystal structure of LP-40/N44 | | 分子名称: | LP-40, N44 | | 著者 | Zhang, X, Wang, X, He, Y. | | 登録日 | 2017-07-19 | | 公開日 | 2017-11-08 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.762 Å) | | 主引用文献 | Enfuvirtide (T20)-Based Lipopeptide Is a Potent HIV-1 Cell Fusion Inhibitor: Implications for Viral Entry and Inhibition
J. Virol., 91, 2017
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6IMM
 | | Cryo-EM structure of an alphavirus, Sindbis virus | | 分子名称: | Assembly protein E3, Octadecane, Spike glycoprotein E1, ... | | 著者 | Zhang, X, Ma, J, Chen, L. | | 登録日 | 2018-10-23 | | 公開日 | 2019-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Implication for alphavirus host-cell entry and assembly indicated by a 3.5 angstrom resolution cryo-EM structure.
Nat Commun, 9, 2018
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5YC0
 | | Crystal structure of LP-46/N44 | | 分子名称: | Envelope glycoprotein, LP-46 | | 著者 | Zhang, X, Wang, X, He, Y. | | 登録日 | 2017-09-05 | | 公開日 | 2018-02-14 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Exceptional potency and structural basis of a T1249-derived lipopeptide fusion inhibitor against HIV-1, HIV-2, and simian immunodeficiency virus
J. Biol. Chem., 293, 2018
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4JDA
 | | Complex structure of abscisic acid receptor PYL3 with (-)-ABA | | 分子名称: | (2Z,4E)-5-[(1R)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, Abscisic acid receptor PYL3 | | 著者 | Zhang, X, Wang, G, Chen, Z. | | 登録日 | 2013-02-24 | | 公開日 | 2013-07-24 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Structural Insights into the Abscisic Acid Stereospecificity by the ABA Receptors PYR/PYL/RCAR
Plos One, 8, 2013
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1CFA
 | | SOLUTION STRUCTURE OF A SEMI-SYNTHETIC C5A RECEPTOR ANTAGONIST AT PH 5.2, 303K, NMR, 20 STRUCTURES | | 分子名称: | COMPLEMENT 5A SEMI-SYNTHETIC ANTAGONIST, SYNTHETIC N-TERMINAL TAIL | | 著者 | Zhang, X, Boyar, W, Galakatos, N, Gonnella, N.C. | | 登録日 | 1996-09-21 | | 公開日 | 1997-09-17 | | 最終更新日 | 2024-06-05 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of a unique C5a semi-synthetic antagonist: implications in receptor binding.
Protein Sci., 6, 1997
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3J4U
 | | A new topology of the HK97-like fold revealed in Bordetella bacteriophage: non-covalent chainmail secured by jellyrolls | | 分子名称: | cementing protein, major capsid protein | | 著者 | Zhang, X, Guo, H, Jin, L, Czornyj, E, Hodes, A, Hui, W.H, Nieh, A.W, Miller, J.F, Zhou, Z.H. | | 登録日 | 2013-10-09 | | 公開日 | 2013-12-25 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | A new topology of the HK97-like fold revealed in Bordetella bacteriophage by cryoEM at 3.5 A resolution.
Elife, 2, 2013
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8YE5
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4OA7
 | | Crystal structure of Tankyrase1 in complex with IWR1 | | 分子名称: | 4-[(3aR,4R,7S,7aS)-1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl]-N-(quinolin-8-yl)benzamide, Tankyrase-1, ZINC ION | | 著者 | Zhang, X, He, H. | | 登録日 | 2014-01-03 | | 公開日 | 2015-01-07 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | | 主引用文献 | Disruption of Wnt/ beta-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells.
Mol.Cell.Biol., 35, 2015
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2B5X
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5T2A
 | | CryoEM structure of the Leishmania donovani 80S ribosome at 2.9 Angstrom resolution | | 分子名称: | 18S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Zhang, X, Lai, M, Zhou, Z.H. | | 登録日 | 2016-08-23 | | 公開日 | 2017-01-25 | | 最終更新日 | 2018-07-18 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes.
Nat Commun, 7, 2016
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4N6F
 | | Crystal structure of Amycolatopsis orientalis BexX complexed with G6P | | 分子名称: | CALCIUM ION, FRUCTOSE -6-PHOSPHATE, Putative thiosugar synthase | | 著者 | Zhang, X, Zhang, Y, Kinsland, C, Sasaki, E, Sun, H.G, Lu, M.J, Liu, T, Ou, A, Li, J, Chen, Y, Liu, H, Ealick, S.E. | | 登録日 | 2013-10-11 | | 公開日 | 2014-05-14 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Co-opting sulphur-carrier proteins from primary metabolic pathways for 2-thiosugar biosynthesis.
Nature, 509, 2014
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2GS6
 | | Crystal Structure of the active EGFR kinase domain in complex with an ATP analog-peptide conjugate | | 分子名称: | CHLORIDE ION, Epidermal growth factor receptor, Peptide, ... | | 著者 | Zhang, X, Gureasko, J, Shen, K, Cole, P.A, Kuriyan, J. | | 登録日 | 2006-04-25 | | 公開日 | 2006-06-20 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor
Cell(Cambridge,Mass.), 125, 2006
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2B5Y
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