8FY0
 
 | | E3:PROTAC:target ternary complex structure (VCB/753b/BCL-xL) | | Descriptor: | Bcl-2-like protein 1, CACODYLIC ACID, Elongin-B, ... | | Authors: | Olsen, S.K, Nayak, D, Lv, D, Yuan, Y, Zhang, P, Hu, W, Lv, Z, Sung, P, Hromas, R, Zheng, G, Zhou, D. | | Deposit date: | 2023-01-25 | | Release date: | 2024-04-10 | | Method: | X-RAY DIFFRACTION (2.94 Å) | | Cite: | Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL.
Nat Commun, 15, 2024
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8C5V
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6XF8
 | | DLP 5 fold | | Descriptor: | Inner capsid protein lambda-1, Inner capsid protein sigma-2, Outer capsid protein mu-1, ... | | Authors: | Sutton, G, Sun, D.P, Fu, X.F, Kotecha, A, Hecksel, G.W, Clare, D.K, Zhang, P, Stuart, D, Boyce, M. | | Deposit date: | 2020-06-15 | | Release date: | 2020-09-23 | | Method: | ELECTRON MICROSCOPY (6.5 Å) | | Cite: | Assembly intermediates of orthoreovirus captured in the cell.
Nat Commun, 11, 2020
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3H4M
 | | AAA ATPase domain of the proteasome- activating nucleotidase | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Proteasome-activating nucleotidase | | Authors: | Jeffrey, P, Zhang, F, Hu, M, Tian, G, Zhang, P, Finley, D, Shi, Y. | | Deposit date: | 2009-04-20 | | Release date: | 2009-06-09 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (3.106 Å) | | Cite: | Structural Insights into the Regulatory Particle of the Proteasome from Methanocaldococcus jannaschii.
Mol.Cell, 34, 2009
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8FAC
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8FE2
 | | Structure of J-PKAc chimera complexed with Aplithianine A | | Descriptor: | 6-[(6M)-6-(1-methyl-1H-imidazol-5-yl)-2,3-dihydro-4H-1,4-thiazin-4-yl]-9H-purine, DnaJ homolog subfamily B member 1, cAMP-dependent protein kinase catalytic subunit alpha, ... | | Authors: | Du, L, Wilson, B.A.P, Li, N, Dalilian, M, Wang, D, Martinez Fiesco, J.A, Smith, E.A, Wamiru, A, Goncharova, E.I, Zhang, P, O'Keefe, B.R. | | Deposit date: | 2022-12-05 | | Release date: | 2023-10-18 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.34 Å) | | Cite: | Discovery and Synthesis of a Naturally Derived Protein Kinase Inhibitor that Selectively Inhibits Distinct Classes of Serine/Threonine Kinases.
J.Nat.Prod., 86, 2023
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8FEC
 | | Structure of J-PKAc chimera complexed with Aplithianine derivative | | Descriptor: | 6-[(6P)-6-(4-bromo-1-methyl-1H-imidazol-5-yl)-2,3-dihydro-4H-1,4-thiazin-4-yl]-7H-purine, DnaJ homolog subfamily B member 1,cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha | | Authors: | Du, L, Wilson, B.A.P, Li, N, Martinez Fiesco, J.A, Dalilian, M, Wang, D, Smith, E.A, Wamiru, A, Goncharova, E.I, Zhang, P, O'Keefe, B.R. | | Deposit date: | 2022-12-06 | | Release date: | 2023-10-18 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Discovery and Synthesis of a Naturally Derived Protein Kinase Inhibitor that Selectively Inhibits Distinct Classes of Serine/Threonine Kinases.
J.Nat.Prod., 86, 2023
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6Q0X
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5IMX
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6LZ7
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6LZ3
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4RFS
 | | Structure of a pantothenate energy coupling factor transporter | | Descriptor: | Energy-coupling factor transporter ATP-binding protein EcfA1, Energy-coupling factor transporter ATP-binding protein EcfA2, Energy-coupling factor transporter transmembrane protein EcfT, ... | | Authors: | Zhang, M, Bao, Z, Zhao, Q, Guo, H, Xu, K, Zhang, P. | | Deposit date: | 2014-09-27 | | Release date: | 2014-12-24 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.232 Å) | | Cite: | Structure of a pantothenate transporter and implications for ECF module sharing and energy coupling of group II ECF transporters.
Proc.Natl.Acad.Sci.USA, 111, 2014
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6SKM
 | | Structure of the native full-length HIV-1 capsid protein A92E in helical assembly (-13,12) | | Descriptor: | Gag protein | | Authors: | Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P. | | Deposit date: | 2019-08-16 | | Release date: | 2020-08-26 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (4.9 Å) | | Cite: | Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.
Nat.Struct.Mol.Biol., 27, 2020
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6SLQ
 | | Structure of the native full-length HIV-1 capsid protein A92E in helical assembly (-12,11) | | Descriptor: | Gag protein | | Authors: | Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P. | | Deposit date: | 2019-08-20 | | Release date: | 2020-09-09 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.
Nat.Struct.Mol.Biol., 27, 2020
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6SLU
 | | Structure of the native full-length HIV-1 capsid protein A92E in helical assembly (-13,11) | | Descriptor: | Gag protein | | Authors: | Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P. | | Deposit date: | 2019-08-20 | | Release date: | 2020-09-09 | | Last modified: | 2022-03-30 | | Method: | ELECTRON MICROSCOPY (4.7 Å) | | Cite: | Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.
Nat.Struct.Mol.Biol., 27, 2020
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6SMU
 | | Structure of the native full-length HIV-1 capsid protein in helical assembly (-13,12) | | Descriptor: | Gag protein | | Authors: | Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P. | | Deposit date: | 2019-08-22 | | Release date: | 2020-09-09 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (5 Å) | | Cite: | Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.
Nat.Struct.Mol.Biol., 27, 2020
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6SKK
 | | Structure of the native full-length HIV-1 capsid protein in helical assembly (-13,8) | | Descriptor: | capsid protein | | Authors: | Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P. | | Deposit date: | 2019-08-15 | | Release date: | 2020-08-26 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.
Nat.Struct.Mol.Biol., 27, 2020
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7BZB
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7BZC
 | | Crystal structure of plant sesterterpene synthase AtTPS18 complexed with farnesyl thiolodiphosphate (FSPP) | | Descriptor: | MAGNESIUM ION, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE, Terpenoid synthase 18 | | Authors: | Li, J.X, Wang, G.D, Zhang, P. | | Deposit date: | 2020-04-27 | | Release date: | 2020-09-23 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.303 Å) | | Cite: | Molecular Basis for Sesterterpene Diversity Produced by Plant Terpene Synthases.
Plant Commun., 1, 2020
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6SKN
 | | Structure of the native full-length HIV-1 capsid protein in helical assembly (-13,8) | | Descriptor: | Gag protein | | Authors: | Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P. | | Deposit date: | 2019-08-16 | | Release date: | 2020-08-26 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.
Nat.Struct.Mol.Biol., 27, 2020
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3H43
 | | N-terminal domain of the proteasome-activating nucleotidase of Methanocaldococcus jannaschii | | Descriptor: | Proteasome-activating nucleotidase | | Authors: | Jeffrey, P.D, Zhang, F, Hu, M, Tian, G, Zhang, P, Finley, D, Shi, Y. | | Deposit date: | 2009-04-17 | | Release date: | 2009-06-09 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural Insights into the Regulatory Particle of the Proteasome from Methanocaldococcus jannaschii.
Mol.Cell, 34, 2009
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4Z7F
 | | Crystal structure of FolT bound with folic acid | | Descriptor: | FOLIC ACID, Folate ECF transporter | | Authors: | Zhao, Q, Wang, C.C, Wang, C.Y, Zhang, P. | | Deposit date: | 2015-04-07 | | Release date: | 2015-07-29 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (3.194 Å) | | Cite: | Structures of FolT in substrate-bound and substrate-released conformations reveal a gating mechanism for ECF transporters
Nat Commun, 6, 2015
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8B12
 | | cryo-EM structure of carboxysomal mini-shell: icosahedral assembly from CsoS4A/1A and CsoS2 co-expression (T = 9) | | Descriptor: | Carboxysome assembly protein CsoS2B, Carboxysome shell vertex protein CsoS4A, Major carboxysome shell protein CsoS1A | | Authors: | Ni, T, Jiang, Q, Liu, L.N, Zhang, P. | | Deposit date: | 2022-09-09 | | Release date: | 2023-08-23 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (1.86 Å) | | Cite: | Intrinsically disordered CsoS2 acts as a general molecular thread for alpha-carboxysome shell assembly.
Nat Commun, 14, 2023
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8B11
 | | cryo-EM structure of carboxysomal mini-shell: icosahedral assembly from CsoS4A/1A and CsoS2 co-expression (T = 4) | | Descriptor: | Carboxysome shell vertex protein CsoS4A, Major carboxysome shell protein CsoS1A | | Authors: | Ni, T, Jiang, Q, Liu, L.N, Zhang, P. | | Deposit date: | 2022-09-08 | | Release date: | 2023-08-23 | | Last modified: | 2023-09-20 | | Method: | ELECTRON MICROSCOPY (2.52 Å) | | Cite: | Intrinsically disordered CsoS2 acts as a general molecular thread for alpha-carboxysome shell assembly.
Nat Commun, 14, 2023
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8B0Y
 | | cryo-EM structure of carboxysomal mini-shell: icosahedral assembly from CsoS4A/1A co-expression (T = 3) | | Descriptor: | Carboxysome shell vertex protein CsoS4A, Major carboxysome shell protein CsoS1A | | Authors: | Ni, T, Jiang, Q, Liu, L.N, Zhang, P. | | Deposit date: | 2022-09-08 | | Release date: | 2023-08-23 | | Last modified: | 2023-09-20 | | Method: | ELECTRON MICROSCOPY (2.79 Å) | | Cite: | Intrinsically disordered CsoS2 acts as a general molecular thread for alpha-carboxysome shell assembly.
Nat Commun, 14, 2023
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