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PDB: 743 件

6LWD
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Crystal structure of human NEIL1(P2G, E3Q, R242) bound to duplex DNA containing spiroiminodihydantoin (Sp)
分子名称: DNA (5'-D(*CP*GP*TP*CP*CP*AP*(DSP)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3'), Endonuclease 8-like 1, ...
著者Liu, M.H, Zhang, J, Zhu, C.X, Zhang, X.X, Gao, Y.Q, Yi, C.Q.
登録日2020-02-07
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes.
Nat Commun, 12, 2021
6LWP
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BU of 6lwp by Molmil
Crystal structure of human NEIL1(R242, Y244R) bound to duplex DNA containing 2'-fluoro-2'-deoxy-5,6-dihydrouridine
分子名称: DNA (5'-D(*CP*GP*TP*CP*CP*AP*(FDU)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3'), Endonuclease 8-like 1, ...
著者Liu, M.H, Zhang, J, Zhu, C.X, Zhang, X.X, Gao, Y.Q, Yi, C.Q.
登録日2020-02-07
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes.
Nat Commun, 12, 2021
6LWH
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Crystal structure of human NEIL1(P2G, E3Q, K242) bound to duplex DNA containing dihydrothymine (DHT)
分子名称: DNA (5'-D(*CP*GP*TP*CP*CP*AP*(TDH)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3'), Endonuclease 8-like 1, ...
著者Liu, M.H, Zhang, J, Zhu, C.X, Zhang, X.X, Gao, Y.Q, Yi, C.Q.
登録日2020-02-07
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes.
Nat Commun, 12, 2021
6LWL
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BU of 6lwl by Molmil
Crystal structure of human NEIL1(R242) bound to duplex DNA containing 2'-fluoro-2'-deoxy-5,6-dihydrouridine
分子名称: DNA (5'-D(*CP*GP*TP*CP*CP*AP*(FDU)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3'), Endonuclease 8-like 1, ...
著者Liu, M.H, Zhang, J, Zhu, C.X, Zhang, X.X, Gao, Y.Q, Yi, C.Q.
登録日2020-02-07
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes.
Nat Commun, 12, 2021
6LWQ
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BU of 6lwq by Molmil
Crystal structure of human NEIL1(R242) bound to duplex DNA containing a C:T mismatch
分子名称: DNA (5'-D(*CP*GP*TP*CP*CP*AP*TP*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3'), Endonuclease 8-like 1
著者Liu, M.H, Zhang, J, Zhu, C.X, Zhang, X.X, Gao, Y.Q, Yi, C.Q.
登録日2020-02-07
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes.
Nat Commun, 12, 2021
6LWR
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BU of 6lwr by Molmil
Crystal structure of human NEIL1(K242) bound to duplex DNA containing a cleaved C:T mismatch
分子名称: DNA (5'-D(*CP*GP*TP*CP*CP*(PDA))-3'), DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3'), Endonuclease 8-like 1
著者Liu, M.H, Zhang, J, Zhu, C.X, Zhang, X.X, Gao, Y.Q, Yi, C.Q.
登録日2020-02-07
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes.
Nat Commun, 12, 2021
8H4Q
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BU of 8h4q by Molmil
Aspergillomarasmine A biosynthese complex with OPS
分子名称: 2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC ACID, Rhodanese domain-containing protein
著者Lu, M, Zhang, J, Wang, Z, Han, L.
登録日2022-10-11
公開日2023-10-18
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Aspergillomarasmine A biosynthese complex with OPS
To Be Published
8H4H
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BU of 8h4h by Molmil
The apo structure of Aspergillomarasmine A synthetase
分子名称: PYRIDOXAL-5'-PHOSPHATE, Rhodanese domain-containing protein
著者Lu, M, Zhang, J, Wang, Z, Han, L.
登録日2022-10-10
公開日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The apo structure of Aspergillomarasmine A synthetase at 2.3 Angstroms resolution
To Be Published
6LMS
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BU of 6lms by Molmil
Solution NMR structure cold shock domain of YB1 from Homo sapiens
分子名称: Y-box-binding protein 1
著者Li, S, Zhang, J, Yang, Y.
登録日2019-12-26
公開日2020-07-22
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis of DNA binding to human YB-1 cold shock domain regulated by phosphorylation.
Nucleic Acids Res., 48, 2020
3QFM
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BU of 3qfm by Molmil
Crystal structure of Streptococcal asymmetric Ap4A hydrolase and phosphodiesterase Spr1479/SapH
分子名称: FE (III) ION, MANGANESE (II) ION, Putative uncharacterized protein
著者Jiang, Y.L, Zhang, J.W, Yu, W.L, Cheng, W, Zhang, C.C, Zhou, C.Z, Chen, Y.
登録日2011-01-22
公開日2011-08-24
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and enzymatic characterization of a Streptococcal ATP/diadenosine polyphosphate and phosphodiester hydrolase Spr1479/SapH
To be Published
7Y72
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BU of 7y72 by Molmil
SARS-CoV-2 spike glycoprotein trimer complexed with Fab fragment of anti-RBD antibody E7 (focused refinement on Fab-RBD interface)
分子名称: Fab E7 heavy chain, Fab E7 light chain, Spike glycoprotein
著者Chia, W.N, Tan, C.W, Tan, A.W.K, Young, B, Starr, T.N, Lopez, E, Fibriansah, G, Barr, J, Cheng, S, Yeoh, A.Y.Y, Yap, W.C, Lim, B.L, Ng, T.S, Sia, W.R, Zhu, F, Chen, S, Zhang, J, Greaney, A.J, Chen, M, Au, G.G, Paradkar, P, Peiris, M, Chung, A.W, Bloom, J.D, Lye, D, Lok, S.M, Wang, L.F.
登録日2022-06-21
公開日2023-08-02
最終更新日2023-08-09
実験手法ELECTRON MICROSCOPY (4.03 Å)
主引用文献Potent pan huACE2-dependent sarbecovirus neutralizing monoclonal antibodies isolated from a BNT162b2-vaccinated SARS survivor.
Sci Adv, 9, 2023
6C5R
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BU of 6c5r by Molmil
Crystal structure of the soluble domain of the mitochondrial calcium uniporter
分子名称: calcium uniporter
著者Fan, C, Fan, M, Fastman, N, Zhang, J, Feng, L.
登録日2018-01-16
公開日2018-07-11
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.09608316 Å)
主引用文献X-ray and cryo-EM structures of the mitochondrial calcium uniporter.
Nature, 559, 2018
7YUL
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BU of 7yul by Molmil
Crystal structure of human BEND6 BEN domain in complex with DNA
分子名称: BEN domain-containing protein 6, DNA (5'-D(*CP*TP*CP*TP*CP*GP*CP*GP*AP*GP*AP*G)-3'), GLYCOLIC ACID
著者Liu, K, Xiao, Y.Q, Zhang, J, Min, J.R.
登録日2022-08-17
公開日2023-04-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Structural insights into DNA recognition by the BEN domain of the transcription factor BANP.
J.Biol.Chem., 299, 2023
7YUN
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BU of 7yun by Molmil
Crystal structure of human BEND6 BEN domain in complex with methylated DNA
分子名称: BEN domain-containing protein 6, DNA (5'-D(*CP*TP*CP*TP*CP*GP*(5CM)P*GP*AP*GP*AP*G)-3')
著者Liu, K, Xiao, Y.Q, Zhang, J, Min, J.R.
登録日2022-08-17
公開日2023-05-03
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Structural insights into DNA recognition by the BEN domain of the transcription factor BANP.
J.Biol.Chem., 299, 2023
7DRA
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BU of 7dra by Molmil
Crystal structure of MERS-CoV 3CL protease (C148A) in spacegroup P212121,pH 9.0
分子名称: 3C-like proteinase
著者Zhang, Y.T, Zhou, X.L, Li, J, Zhang, J.
登録日2020-12-27
公開日2021-12-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.784097 Å)
主引用文献Crystal structure of MERS-CoV 3CL protease (C148A) in spacegroup P212121,pH 9.0
To Be Published
6C5W
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BU of 6c5w by Molmil
Crystal structure of the mitochondrial calcium uniporter
分子名称: CALCIUM ION, calcium uniporter, nanobody
著者Fan, C, Fan, M, Fastman, N, Zhang, J, Feng, L.
登録日2018-01-17
公開日2018-07-11
最終更新日2019-04-24
実験手法X-RAY DIFFRACTION (3.10010242 Å)
主引用文献X-ray and cryo-EM structures of the mitochondrial calcium uniporter.
Nature, 559, 2018
4LYB
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BU of 4lyb by Molmil
CdS within a lysoyzme single crystal
分子名称: CADMIUM ION, Lysozyme C
著者Wei, H, House, S, Wu, J, Zhang, J, Wang, Z, He, Y, Gao, Y.-G, Robinson, H, Li, W, Zuo, J.-M, Robertson, I.M, Lu, Y.
登録日2013-07-30
公開日2015-02-25
実験手法X-RAY DIFFRACTION (1.21 Å)
主引用文献Enhanced and tunable fluorescent quantum dots within a single crystal of protein
TO BE PUBLISHED
5YTG
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BU of 5ytg by Molmil
Structure of large fragment of DNA Polymerase I from Thermus aquaticus Host-Guest complex with the unnatural base I-fC pair with dA
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*AP*AP*CP*GP*GP*CP*GP*CP*CP*GP*(94O)P*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), ...
著者Zeng, H, Mondal, M, Song, R.Y, Zhang, J, Xia, B, Gao, Y.Q, Yi, C.Q.
登録日2017-11-17
公開日2018-11-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Unnatural Cytosine Bases Recognized as Thymines by DNA Polymerases by the Formation of the Watson-Crick Geometry.
Angew. Chem. Int. Ed. Engl., 58, 2019
5YTH
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BU of 5yth by Molmil
Structure of large fragment of DNA Polymerase I from Thermus aquaticus Host-Guest complex with the unnatural base M-fC pair with dG
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*AP*AP*CP*GP*GP*CP*GP*CP*CP*GP*(92F)P*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*GP*CP*GP*GP*CP*GP*CP*(DOC))-3'), ...
著者Zeng, H, Mondal, M, Song, R.Y, Zhang, J, Xia, B, Gao, Y.Q, Yi, C.Q.
登録日2017-11-17
公開日2018-11-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Unnatural Cytosine Bases Recognized as Thymines by DNA Polymerases by the Formation of the Watson-Crick Geometry.
Angew. Chem. Int. Ed. Engl., 58, 2019
5Z3N
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BU of 5z3n by Molmil
Structure of large fragment of DNA Polymerase I from Thermus aquaticus Host-Guest complex with the unnatural base 5fC pair with dA
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*AP*AP*CP*GP*GP*CP*GP*CP*CP*GP*(5FC)P*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), ...
著者Zeng, H, Mondal, M, Song, R.Y, Zhang, J, Xia, B, Gao, Y.Q, Yi, C.Q.
登録日2018-01-08
公開日2018-11-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Unnatural Cytosine Bases Recognized as Thymines by DNA Polymerases by the Formation of the Watson-Crick Geometry.
Angew. Chem. Int. Ed. Engl., 58, 2019
7XAX
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BU of 7xax by Molmil
Crystal structure of SARS coronavirus main protease in complex with Baicalei
分子名称: 3C-like proteinase nsp5, 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one
著者Zhou, X.L, Li, J, Zhang, J.
登録日2022-03-19
公開日2023-03-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structure of SARS coronavirus main protease in complex with Baicalei
To Be Published
7XB3
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BU of 7xb3 by Molmil
Crystal structure of SARS-Cov-2 main protease D48N mutant
分子名称: Replicase polyprotein 1a
著者Hu, X.H, Li, J, Zhang, J.
登録日2022-03-20
公開日2023-03-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Crystal structure of SARS-Cov-2 main protease D48N mutant
To Be Published
4DNU
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BU of 4dnu by Molmil
Crystal structure of the W285A mutant of UVB-resistance protein UVR8
分子名称: AT5g63860/MGI19_6
著者Wu, D, Hu, Q, Yan, Z, Chen, W, Yan, C, Zhang, J, Wang, J, Shi, Y.
登録日2012-02-09
公開日2012-03-07
最終更新日2013-07-17
実験手法X-RAY DIFFRACTION (1.764 Å)
主引用文献Structural basis of ultraviolet-B perception by UVR8.
Nature, 484, 2012
7Y78
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Crystal structure of Cry78Aa
分子名称: 1,2-ETHANEDIOL, AMMONIUM ION, Toxin
著者Cao, B.B, Nie, Y.F, Wang, N.C, Guan, Z.Y, Zhang, D.L, Zhang, J.
登録日2022-06-21
公開日2022-08-31
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The crystal structure of Cry78Aa from Bacillus thuringiensis provides insights into its insecticidal activity.
Commun Biol, 5, 2022
4NTJ
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BU of 4ntj by Molmil
Structure of the human P2Y12 receptor in complex with an antithrombotic drug
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHOLESTEROL, P2Y purinoceptor 12,Soluble cytochrome b562,P2Y purinoceptor 12, ...
著者Zhang, K, Zhang, J, Gao, Z.-G, Zhang, D, Zhu, L, Han, G.W, Moss, S.M, Paoletta, S, Kiselev, E, Lu, W, Fenalti, G, Zhang, W, Muller, C.E, Yang, H, Jiang, H, Cherezov, V, Katritch, V, Jacobson, K.A, Stevens, R.C, Wu, B, Zhao, Q, GPCR Network (GPCR)
登録日2013-12-02
公開日2014-03-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Structure of the human P2Y12 receptor in complex with an antithrombotic drug
Nature, 509, 2014

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