7VOK
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7VMX
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4IMA
| The structure of C436M-hLPYK in complex with Citrate/Mn/ATP/Fru-1,6-BP | 分子名称: | 1,2-ETHANEDIOL, 1,6-di-O-phosphono-beta-D-fructofuranose, ADENOSINE, ... | 著者 | Zhang, B, Holyoak, T, Fenton, A.W, Tang, Q.L, Prasannan, C.B, Deng, J.P. | 登録日 | 2013-01-02 | 公開日 | 2013-01-23 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.954 Å) | 主引用文献 | Energetic Coupling between an Oxidizable Cysteine and the Phosphorylatable N-Terminus of Human Liver Pyruvate Kinase. Biochemistry, 52, 2013
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7SUX
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7SV0
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7SUZ
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8I16
| Crystal structure of the selenomethionine (SeMet)-derived Cas12g (D513A) mutant | 分子名称: | Cas12g, ZINC ION | 著者 | Zhang, B, Chen, J, Ye, Y.M, OuYang, S.Y. | 登録日 | 2023-01-12 | 公開日 | 2023-08-30 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Structural transitions upon guide RNA binding and their importance in Cas12g-mediated RNA cleavage. Plos Genet., 19, 2023
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6IV8
| the selenomethionine(SeMet)-derived Cas13d binary complex | 分子名称: | MAGNESIUM ION, RNA (51-MER), RNA (53-MER), ... | 著者 | Zhang, B, Ye, Y.M, Ye, W.W, OuYang, S.Y. | 登録日 | 2018-12-02 | 公開日 | 2019-06-19 | 最終更新日 | 2019-06-26 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Two HEPN domains dictate CRISPR RNA maturation and target cleavage in Cas13d. Nat Commun, 10, 2019
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6S7V
| Lipoteichoic acids flippase LtaA | 分子名称: | MFS transporter | 著者 | Zhang, B, Perez, C. | 登録日 | 2019-07-06 | 公開日 | 2020-04-22 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (3.301 Å) | 主引用文献 | Structure of a proton-dependent lipid transporter involved in lipoteichoic acids biosynthesis. Nat.Struct.Mol.Biol., 27, 2020
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6IV9
| the Cas13d binary complex | 分子名称: | Cas13d, MAGNESIUM ION, crRNA (50-MER) | 著者 | Zhang, B, Ye, Y.M, Ye, W.W, OuYang, S.Y. | 登録日 | 2018-12-02 | 公開日 | 2019-06-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Two HEPN domains dictate CRISPR RNA maturation and target cleavage in Cas13d. Nat Commun, 10, 2019
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4XO7
| Crystal structure of human 3-alpha hydroxysteroid dehydrogenase type 3 in complex with NADP+, 5alpha-androstan-3,17-dione and (3beta, 5alpha)-3-hydroxyandrostan-17-one | 分子名称: | 4-ANDROSTENE-3-17-DIONE, Aldo-keto reductase family 1 member C2, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Zhang, B, Hu, X.-J, Lin, S.-X. | 登録日 | 2015-01-16 | 公開日 | 2016-02-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Human 3 alpha-hydroxysteroid dehydrogenase type 3: structural clues of 5 alpha-DHT reverse binding and enzyme down-regulation decreasing MCF7 cell growth. Biochem.J., 473, 2016
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4XO6
| Crystal structure of human 3-alpha hydroxysteroid dehydrogenase type 3 in complex with NADP+, 5alpha-androstan-3,17-dione and (3beta, 5alpha)-3-hydroxyandrostan-17-one | 分子名称: | (3Beta,5alpha)-3-Hydroxyandrostan-17-one, 1,2-ETHANEDIOL, 5ALPHA-ANDROSTAN-3,17-DIONE, ... | 著者 | Zhang, B, Hu, X.-J, Lin, S.-X. | 登録日 | 2015-01-16 | 公開日 | 2016-02-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Human 3 alpha-hydroxysteroid dehydrogenase type 3: structural clues of 5 alpha-DHT reverse binding and enzyme down-regulation decreasing MCF7 cell growth. Biochem.J., 473, 2016
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8DJU
| Cytosolic ascorbate peroxidase from Sorghum bicolor - bicyclic dehydroascorbic acid complex | 分子名称: | (3aS,6S,6aR)-3,3,3a,6-tetrahydroxytetrahydrofuro[3,2-b]furan-2(3H)-one (non-preferred name), L-ascorbate peroxidase, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Zhang, B, Kang, C. | 登録日 | 2022-07-01 | 公開日 | 2023-01-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | A sorghum ascorbate peroxidase with four binding sites has activity against ascorbate and phenylpropanoids. Plant Physiol., 192, 2023
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8KIH
| PhmA, a type I diterpene synthase without NST/DTE motif | 分子名称: | (2Z,6E,10E)-2-fluoro-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl trihydrogen diphosphate, MAGNESIUM ION, diterpene synthase, ... | 著者 | Zhang, B, Ge, H.M, Zhu, A, Zhang, Y. | 登録日 | 2023-08-23 | 公開日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Biosynthesis of Platelet Activating Factor Antagonist Phomactins Revealing a New Class of Type I Diterpene Synthase To Be Published
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8KI5
| PhmA, a type I diterpene synthase without NST/DTE motif | 分子名称: | (2Z,6Z)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol, PhmA | 著者 | Zhang, B, Ge, H.M, Zhu, A, Zhang, Y. | 登録日 | 2023-08-22 | 公開日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Biosynthesis of Platelet Activating Factor Antagonist Phomactins Revealing a New Class of Type I Diterpene Synthase To Be Published
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8JAB
| Crystal structure of Mycobacterium tuberculosis LpqY in complex with trehalose analogue YB-06 | 分子名称: | (2~{S},3~{S},4~{R},5~{S},6~{R})-2-(fluoranylmethyl)-6-[(2~{R},3~{R},4~{S},5~{S},6~{S})-6-(fluoranylmethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-oxane-3,4,5-triol, SULFATE ION, Trehalose-binding lipoprotein LpqY | 著者 | Zhang, B, Liang, J, Rao, Z. | 登録日 | 2023-05-05 | 公開日 | 2023-09-27 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Molecular recognition of trehalose and trehalose analogues by Mycobacterium tuberculosis LpqY-SugABC. Proc.Natl.Acad.Sci.USA, 120, 2023
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8JAC
| Crystal structure of Mycobacterium tuberculosis LpqY in complex with trehalose analogue YB-16 | 分子名称: | N-[[(2R,3S,4S,5R,6S)-3,4,5,6-tetrakis(oxidanyl)oxan-2-yl]methyl]ethanamide, SULFATE ION, Trehalose-binding lipoprotein LpqY, ... | 著者 | Zhang, B, Liang, J, Rao, Z. | 登録日 | 2023-05-05 | 公開日 | 2023-09-27 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Molecular recognition of trehalose and trehalose analogues by Mycobacterium tuberculosis LpqY-SugABC. Proc.Natl.Acad.Sci.USA, 120, 2023
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8JA7
| Cryo-EM structure of Mycobacterium tuberculosis LpqY-SugABC in complex with trehalose | 分子名称: | Trehalose import ATP-binding protein SugC, Trehalose transport system permease protein SugA, Trehalose transport system permease protein SugB, ... | 著者 | Zhang, B, Liang, J, Rao, Z. | 登録日 | 2023-05-05 | 公開日 | 2023-09-27 | 最終更新日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | 主引用文献 | Molecular recognition of trehalose and trehalose analogues by Mycobacterium tuberculosis LpqY-SugABC. Proc.Natl.Acad.Sci.USA, 120, 2023
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8JA9
| Crystal structure of Mycobacterium tuberculosis LpqY in complex with trehalose analogue YB-03 | 分子名称: | SULFATE ION, Trehalose-binding lipoprotein LpqY, alpha-D-glucopyranose-(1-1)-(2~{S},3~{R},4~{S},5~{S},6~{S})-6-[(2-azanylhydrazinyl)methyl]oxane-2,3,4,5-tetrol | 著者 | Zhang, B, Liang, J, Rao, Z. | 登録日 | 2023-05-05 | 公開日 | 2023-10-04 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Molecular recognition of trehalose and trehalose analogues by Mycobacterium tuberculosis LpqY-SugABC. Proc.Natl.Acad.Sci.USA, 120, 2023
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8JAA
| Crystal structure of Mycobacterium tuberculosis LpqY in complex with trehalose analogue YB-04 | 分子名称: | (2~{S},3~{R},4~{S},5~{S},6~{S})-6-[(2-azanylhydrazinyl)methyl]oxane-2,3,4,5-tetrol, SULFATE ION, Trehalose-binding lipoprotein LpqY | 著者 | Zhang, B, Liang, J, Rao, Z. | 登録日 | 2023-05-05 | 公開日 | 2023-10-04 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Molecular recognition of trehalose and trehalose analogues by Mycobacterium tuberculosis LpqY-SugABC. Proc.Natl.Acad.Sci.USA, 120, 2023
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6AJH
| Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with AU1235 | 分子名称: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, 1-(2-adamantyl)-3-[2,3,4-tris(fluoranyl)phenyl]urea, Drug exporters of the RND superfamily-like protein,Endolysin, ... | 著者 | Zhang, B, Li, J, Yang, X.L, Wu, L.J, Yang, H.T, Rao, Z.H. | 登録日 | 2018-08-27 | 公開日 | 2018-12-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.818 Å) | 主引用文献 | Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target. Cell, 176, 2019
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6AJI
| Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with Rimonabant | 分子名称: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide, Drug exporters of the RND superfamily-like protein,Endolysin, ... | 著者 | Zhang, B, Li, J, Yang, X.L, Wu, L.J, Yang, H.T, Rao, Z.H. | 登録日 | 2018-08-27 | 公開日 | 2018-12-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target. Cell, 176, 2019
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6AJF
| Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis | 分子名称: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, Drug exporters of the RND superfamily-like protein,Endolysin, alpha-D-glucopyranosyl 6-O-dodecyl-alpha-D-glucopyranoside | 著者 | Zhang, B, Li, J, Yang, X.L, Wu, L.J, Yang, H.T, Rao, Z.H. | 登録日 | 2018-08-27 | 公開日 | 2018-12-26 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.698 Å) | 主引用文献 | Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target. Cell, 176, 2019
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6AJG
| Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with SQ109 | 分子名称: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, DODECYL-BETA-D-MALTOSIDE, Drug exporters of the RND superfamily-like protein,Endolysin, ... | 著者 | Zhang, B, Li, J, Yang, X.L, Wu, L.J, Yang, H.T, Rao, Z.H. | 登録日 | 2018-08-27 | 公開日 | 2018-12-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.604 Å) | 主引用文献 | Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target. Cell, 176, 2019
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6AJJ
| Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with ICA38 | 分子名称: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, 4,6-difluoro-N-(spiro[5.5]undecan-3-yl)-1H-indole-2-carboxamide, Drug exporters of the RND superfamily-like protein,Endolysin, ... | 著者 | Zhang, B, Li, J, Yang, X.L, Wu, L.J, Yang, H.T, Rao, Z.H. | 登録日 | 2018-08-27 | 公開日 | 2018-12-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.794 Å) | 主引用文献 | Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target. Cell, 176, 2019
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