8WUL
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![BU of 8wul by Molmil](/molmil-images/mine/8wul) | Crystal structure of affinity enhanced TCR in complex with HLA-A*11:01 bound to KRAS-G12V peptide (VVGAVGVGK) | 分子名称: | Beta-2-microglobulin, KRAS-G12V nonamer peptide, MHC class I antigen, ... | 著者 | Zhang, M.Y, Luo, L.J, Xu, W, Guan, F.H, Wang, X.Y, Zhu, P, Zhang, J.H, Zhou, X.Y, Wang, F, Ye, S. | 登録日 | 2023-10-20 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Identification and affinity enhancement of T-cell receptor targeting a KRAS G12V cancer neoantigen. Commun Biol, 7, 2024
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7BRM
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![BU of 7brm by Molmil](/molmil-images/mine/7brm) | Architecture of curli complex | 分子名称: | Curli production assembly/transport protein CsgG, csgf | 著者 | Zhang, M, Shi, H. | 登録日 | 2020-03-29 | 公開日 | 2020-07-15 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Cryo-EM structure of the nonameric CsgG-CsgF complex and its implications for controlling curli biogenesis in Enterobacteriaceae. Plos Biol., 18, 2020
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5TO2
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3X0F
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3X0E
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![BU of 3x0e by Molmil](/molmil-images/mine/3x0e) | |
3X0G
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7YKI
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![BU of 7yki by Molmil](/molmil-images/mine/7yki) | Crystal structure of MAGI2 PDZ0-GK domain in complex with phospho-SAPAP1 GBR3 peptide | 分子名称: | GLYCEROL, Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2, ... | 著者 | Zhang, M, Lin, L, Zhu, J. | 登録日 | 2022-07-22 | 公開日 | 2023-08-02 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Phosphorylation-dependent recognition of diverse protein targets by the cryptic GK domain of MAGI MAGUKs. Sci Adv, 9, 2023
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4G28
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![BU of 4g28 by Molmil](/molmil-images/mine/4g28) | Calcium-calmodulin complexed with the calmodulin binding domain from a small conductance potassium channel splice variant and EBIO-1 | 分子名称: | 1-ethyl-1,3-dihydro-2H-benzimidazol-2-one, CALCIUM ION, Calmodulin, ... | 著者 | Zhang, M, Pascal, J.M, Zhang, J.-F. | 登録日 | 2012-07-11 | 公開日 | 2012-09-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Identification of the functional binding pocket for compounds targeting small-conductance Ca(2+)-activated potassium channels. Nat Commun, 3, 2012
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4G27
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![BU of 4g27 by Molmil](/molmil-images/mine/4g27) | Calcium-calmodulin complexed with the calmodulin binding domain from a small conductance potassium channel splice variant and phenylurea | 分子名称: | 1-phenylurea, CALCIUM ION, Calmodulin, ... | 著者 | Zhang, M, Pascal, J.M, Zhang, J.-F. | 登録日 | 2012-07-11 | 公開日 | 2012-09-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Identification of the functional binding pocket for compounds targeting small-conductance Ca(2+)-activated potassium channels. Nat Commun, 3, 2012
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4WY4
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![BU of 4wy4 by Molmil](/molmil-images/mine/4wy4) | Crystal structure of autophagic SNARE complex | 分子名称: | Synaptosomal-associated protein 29, Syntaxin-17, Vesicle-associated membrane protein 8 | 著者 | Zhao, M, Brunger, A.T. | 登録日 | 2014-11-15 | 公開日 | 2015-02-11 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes. Nature, 520, 2015
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8OOS
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![BU of 8oos by Molmil](/molmil-images/mine/8oos) | CryoEM Structure INO80core Hexasome complex ATPase-hexasome refinement state 2 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Chromatin-remodeling ATPase Ino80, DNA Strand 2, ... | 著者 | Zhang, M, Jungblut, A, Hoffmann, T, Eustermann, S. | 登録日 | 2023-04-05 | 公開日 | 2023-07-26 | 最終更新日 | 2023-08-02 | 実験手法 | ELECTRON MICROSCOPY (3.29 Å) | 主引用文献 | Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling. Science, 381, 2023
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3FQ9
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![BU of 3fq9 by Molmil](/molmil-images/mine/3fq9) | Design of an insulin analog with enhanced receptor-binding selectivity. Rationale, structure, and therapeutic implications | 分子名称: | Insulin, ZINC ION | 著者 | Zhao, M, Wan, Z.L, Whittaker, L, Xu, B, Phillips, N, Katsoyannis, P, Whittaker, J, Weiss, M.A. | 登録日 | 2009-01-07 | 公開日 | 2009-08-04 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Design of an insulin analog with enhanced receptor binding selectivity: rationale, structure, and therapeutic implications. J.Biol.Chem., 284, 2009
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3Q25
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![BU of 3q25 by Molmil](/molmil-images/mine/3q25) | Crystal structure of human alpha-synuclein (1-19) fused to maltose binding protein (MBP) | 分子名称: | GLYCEROL, Maltose-binding periplasmic protein/alpha-synuclein chimeric protein, SULFATE ION, ... | 著者 | Zhao, M, Sawaya, M.R, Cascio, D, Eisenberg, D. | 登録日 | 2010-12-19 | 公開日 | 2011-06-01 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structures of segments of alpha-synuclein fused to maltose-binding protein suggest intermediate states during amyloid formation Protein Sci., 20, 2011
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7YFI
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![BU of 7yfi by Molmil](/molmil-images/mine/7yfi) | Structure of the Rat tri-heteromeric GluN1-GluN2A-GluN2C NMDA receptor in complex with glycine and glutamate | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ... | 著者 | Zhang, M, Zhang, J, Guo, F, Li, Y, Zhu, S. | 登録日 | 2022-07-08 | 公開日 | 2023-03-29 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits. Nat.Struct.Mol.Biol., 30, 2023
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7YKF
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![BU of 7ykf by Molmil](/molmil-images/mine/7ykf) | Crystal structure of MAGI2 PDZ0-GK/pEphexin4 complex | 分子名称: | Ephexin4, Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 | 著者 | Zhang, M, Lin, L, Zhu, J. | 登録日 | 2022-07-22 | 公開日 | 2023-08-02 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Phosphorylation-dependent recognition of diverse protein targets by the cryptic GK domain of MAGI MAGUKs. Sci Adv, 9, 2023
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7YKG
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![BU of 7ykg by Molmil](/molmil-images/mine/7ykg) | Crystal structure of MAGI2 PDZ0-GK/pSGEF complex | 分子名称: | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2, SGEF | 著者 | Zhang, M, Lin, L, Zhu, J. | 登録日 | 2022-07-22 | 公開日 | 2023-08-02 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Phosphorylation-dependent recognition of diverse protein targets by the cryptic GK domain of MAGI MAGUKs. Sci Adv, 9, 2023
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4GEH
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4QNH
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![BU of 4qnh by Molmil](/molmil-images/mine/4qnh) | Calcium-calmodulin (T79D) complexed with the calmodulin binding domain from a small conductance potassium channel SK2-a | 分子名称: | CALCIUM ION, Calmodulin, SULFATE ION, ... | 著者 | Zhang, M, Pascal, J.M, Logothetis, D.E, Zhang, J.F. | 登録日 | 2014-06-17 | 公開日 | 2014-08-06 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Selective phosphorylation modulates the PIP2 sensitivity of the CaM-SK channel complex. Nat.Chem.Biol., 10, 2014
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4E0M
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![BU of 4e0m by Molmil](/molmil-images/mine/4e0m) | SVQIVYK segment from human Tau (305-311) displayed on 54-membered macrocycle scaffold (form I) | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Cyclic pseudo-peptide SVQIVYK(ORN)EF(HAO)(4BF)K(ORN), PHOSPHATE ION | 著者 | Zhao, M, Liu, C, Michael, S.R, Eisenberg, D. | 登録日 | 2012-03-04 | 公開日 | 2013-02-13 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Out-of-register beta-sheets suggest a pathway
to toxic amyloid aggregates Proc.Natl.Acad.Sci.USA, 109, 2012
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8WTE
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![BU of 8wte by Molmil](/molmil-images/mine/8wte) | Crystal structure of TCR in complex with HLA-A*11:01 bound to KRAS-G12V peptide (VVGAVGVGK) | 分子名称: | Beta-2-microglobulin, KRAS-G12V nonamer peptide, MHC class I antigen (Fragment), ... | 著者 | Zhang, M.Y, Luo, L.J, Xu, W, Guan, F.H, Wang, X.Y, Zhu, P, Zhang, J.H, Zhou, X.Y, Wang, F, Ye, S. | 登録日 | 2023-10-18 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Identification and affinity enhancement of T-cell receptor targeting a KRAS G12V cancer neoantigen. Commun Biol, 7, 2024
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4E0K
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![BU of 4e0k by Molmil](/molmil-images/mine/4e0k) | Crystal Structure of the amyloid-fibril forming peptide KDWSFY derived from human Beta 2 Microglobulin (58-63) | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Amyloidogenic peptide segment KDWSFY, SODIUM ION | 著者 | Zhao, M, Liu, C, Sawaya, M.R, Eisenberg, D. | 登録日 | 2012-03-04 | 公開日 | 2012-12-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (0.97 Å) | 主引用文献 | Out-of-register beta-sheets suggest a pathway to toxic amyloid aggregates. Proc.Natl.Acad.Sci.USA, 109, 2012
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4E0O
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![BU of 4e0o by Molmil](/molmil-images/mine/4e0o) | SVQIVYK segment from human Tau (305-311) displayed on 54-membered macrocycle scaffold (form III) | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Cyclic pseudo-peptide SVQIVYK(ORN)EF(HAO)(4BF)K(ORN), PHOSPHATE ION | 著者 | Zhao, M, Liu, C, Sawaya, M.R, Eisenberg, D. | 登録日 | 2012-03-04 | 公開日 | 2012-12-19 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Out-of-register beta-sheets suggest a pathway to toxic amyloid aggregates. Proc.Natl.Acad.Sci.USA, 109, 2012
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8GRS
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![BU of 8grs by Molmil](/molmil-images/mine/8grs) | human TMEM63A | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CSC1-like protein 1 | 著者 | Zhang, M.F. | 登録日 | 2022-09-02 | 公開日 | 2023-06-14 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | A mechanical-coupling mechanism in OSCA/TMEM63 channel mechanosensitivity. Nat Commun, 14, 2023
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8GRN
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![BU of 8grn by Molmil](/molmil-images/mine/8grn) | AtOSCA1.1 extended state | 分子名称: | Protein OSCA1, [1-MYRISTOYL-GLYCEROL-3-YL]PHOSPHONYLCHOLINE | 著者 | Zhang, M.F. | 登録日 | 2022-09-02 | 公開日 | 2023-06-14 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | A mechanical-coupling mechanism in OSCA/TMEM63 channel mechanosensitivity. Nat Commun, 14, 2023
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8GSO
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![BU of 8gso by Molmil](/molmil-images/mine/8gso) | AtOSCA3.1 channel extended state | 分子名称: | CSC1-like protein ERD4 | 著者 | Zhang, M.F. | 登録日 | 2022-09-06 | 公開日 | 2023-06-14 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | A mechanical-coupling mechanism in OSCA/TMEM63 channel mechanosensitivity. Nat Commun, 14, 2023
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