8KHR
 
 | | Cryo-EM structure of EBV gH/gL-gp42 in complex with fab 2C1 | | 分子名称: | 2C1 heavy chain, 2C1 light chain, Envelope glycoprotein H, ... | | 著者 | Fang, X.Y, Zhao, G.X, Zeng, M.S, Liu, Z. | | 登録日 | 2023-08-22 | | 公開日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | | 主引用文献 | Potent human monoclonal antibodies targeting Epstein-Barr virus gp42 reveal vulnerable sites for virus infection.
Cell Rep Med, 5, 2024
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8KFA
 | | Cryo-EM structure of HSV-1 gB with D48 Fab complex | | 分子名称: | D48 heavy chain, D48 light chain, Envelope glycoprotein B | | 著者 | Yang, J, Sun, C, Fang, X, Zeng, M, Liu, Z. | | 登録日 | 2023-08-15 | | 公開日 | 2024-01-03 | | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | | 主引用文献 | The structure of HSV-1 gB bound to a potent neutralizing antibody reveals a conservative antigenic domain across herpesviruses
hlife, 2023
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5IZU
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5IWZ
 | | Synaptonemal complex protein | | 分子名称: | Synaptonemal complex protein 2 | | 著者 | Feng, J, Fu, S, Cao, X, Wu, H, Lu, J, Zeng, M, Liu, L, Yang, X, Shen, Y. | | 登録日 | 2016-03-23 | | 公開日 | 2017-03-29 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.098 Å) | | 主引用文献 | Structure of synaptonemal complexes protein at 2.6 angstroms resolution
To Be Published
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7D5Z
 | | Crystal structure of EBV gH/gL bound with neutralizing antibody 1D8 | | 分子名称: | Envelope glycoprotein H, Envelope glycoprotein L, heavy chain of 1D8, ... | | 著者 | Zhu, Q, Shan, S, Yu, J, Wang, X, Zhang, L, Zeng, M. | | 登録日 | 2020-09-28 | | 公開日 | 2021-10-20 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | | 主引用文献 | A Neutralizing Antibody Targeting a New Site of Vulnerability on Epstein-Barr Virus gH/gL Protects against Dual-Tropic Infection
To Be Published
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5T35
 | | The PROTAC MZ1 in complex with the second bromodomain of Brd4 and pVHL:ElonginC:ElonginB | | 分子名称: | (2~{S},4~{R})-1-[(2~{S})-2-[2-[2-[2-[2-[2-[(9~{S})-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12-pentaen-9-yl]ethanoylamino]ethoxy]ethoxy]ethoxy]ethanoylamino]-3,3-dimethyl-butanoyl]-~{N}-[[4-(4-methyl-2,3-dihydro-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Bromodomain-containing protein 4, Transcription elongation factor B polypeptide 1, ... | | 著者 | Gadd, M.S, Zengerle, M, Ciulli, A. | | 登録日 | 2016-08-24 | | 公開日 | 2017-03-08 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis of PROTAC cooperative recognition for selective protein degradation.
Nat. Chem. Biol., 13, 2017
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8AQF
 | | CRYSTAL STRUCTURE OF HUMAN MONOGLYCERIDE LIPASE WITH COMPOUND LEI-515 | | 分子名称: | 1-[(~{R})-[2-chloranyl-4-[(2~{S},3~{S})-4-(3-chlorophenyl)-2,3-dimethyl-piperazin-1-yl]carbonyl-phenyl]sulfinyl]-3,3-bis(fluoranyl)pentan-2-one, Monoglyceride lipase | | 著者 | Jiang, M, Huizenga, M, Wirt, J, Paloczi, J, Amedi, A, van der Berg, R, Benz, J, Collin, L, Deng, H, Driever, W, Florea, B, Grether, U, Janssen, A, Heitman, L, Lam, T.W, Mohr, F, Pavlovic, A, Ruf, I, Rutjes, H, Stevens, F, van der Vliet, D, van der Wel, T, Wittwer, M, Boeckel, C, Pacher, P, Hohmann, A, van der Stelt, M. | | 登録日 | 2022-08-12 | | 公開日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Discovery of a peripheral restricted, reversible monoacylglycerol lipase inhibitor that reduces liver injury and chemotherapy-induced neuropathy
To Be Published
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