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PDB: 102 件

6C5M
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Structure of glycolipid aGSA[8,9] in complex with mouse CD1d
分子名称: (5R,6S,7S)-5,6-dihydroxy-N-nonyl-7-(octanoylamino)-8-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}octanamide (non-preferred name), 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zajonc, D.M, Wang, J.
登録日2018-01-16
公開日2019-01-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献A molecular switch in mouse CD1d modulates natural killer T cell activation by alpha-galactosylsphingamides.
J.Biol.Chem., 294, 2019
6C6J
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Structure of glycolipid aGSA[8,P5p] in complex with mouse CD1d
分子名称: (5R,6S,7S)-5,6-dihydroxy-7-(octanoylamino)-N-(4-pentylphenyl)-8-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)te trahydro-2H-pyran-2-yl]oxy}octanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
著者Zajonc, D.M, Wang, J.
登録日2018-01-18
公開日2019-01-30
最終更新日2020-08-19
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献A molecular switch in mouse CD1d modulates natural killer T cell activation by alpha-galactosylsphingamides.
J.Biol.Chem., 294, 2019
3UBX
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Crystal structure of the mouse CD1d-C20:2-aGalCer-L363 mAb Fab complex
分子名称: (11Z,14Z)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]icosa-11,14-dienamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yu, E.D, Zajonc, D.M.
登録日2011-10-25
公開日2011-11-16
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis for the recognition of C20:2-alpha GalCer by the invariant natural killer T cell receptor-like antibody L363.
J.Biol.Chem., 287, 2012
4U6H
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Vaccinia L1/M12B9-Fab complex
分子名称: Heavy chain of murine anti-vaccinia L1 IgG2a antibody M12B9, Light chain of murine anti-vaccinia L1 IgG2a antibody M12B9, Protein L1
著者Matho, M.H, Schlossman, A, Zajonc, D.M.
登録日2014-07-29
公開日2014-08-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Potent neutralization of vaccinia virus by divergent murine antibodies targeting a common site of vulnerability in l1 protein.
J.Virol., 88, 2014
5FA4
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BU of 5fa4 by Molmil
Structure of HLA-A2:01 with peptide Y16R
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Remesh, S.G, Zajonc, D.M.
登録日2015-12-10
公開日2016-12-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Unconventional Peptide Presentation by Major Histocompatibility Complex (MHC) Class I Allele HLA-A*02:01: BREAKING CONFINEMENT.
J. Biol. Chem., 292, 2017
5FKP
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Crystal structure of the mouse CD1d in complex with the p99 peptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIGEN-PRESENTING GLYCOPROTEIN CD1D1, BETA 2 MICROGLOBULIN, ...
著者Girardi, E, Wang, J, Zajonc, D.M.
登録日2015-10-18
公開日2016-03-30
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of an Alpha-Helical Peptide and Lipopeptide Bound to the Non-Classical Mhc Class I Molecule Cd1D
J.Biol.Chem., 291, 2016
4F7C
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Crystal structure of bovine CD1d with bound C12-di-sulfatide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, CD1D antigen, ...
著者Wang, J, Zajonc, D.M.
登録日2012-05-15
公開日2012-11-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.864 Å)
主引用文献Crystal Structures of Bovine CD1d Reveal Altered αGalCer Presentation and a Restricted A' Pocket Unable to Bind Long-Chain Glycolipids.
Plos One, 7, 2012
4F7E
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Crystal structure of bovine CD1d with bound C16:0-alpha-galactosyl ceramide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ...
著者Wang, J, Zajonc, D.M.
登録日2012-05-15
公開日2012-11-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structures of Bovine CD1d Reveal Altered αGalCer Presentation and a Restricted A' Pocket Unable to Bind Long-Chain Glycolipids.
Plos One, 7, 2012
5F9J
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Structure of HLA-A2:01 with peptide Y9L
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Remesh, S.G, Zajonc, D.M.
登録日2015-12-09
公開日2016-12-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Unconventional Peptide Presentation by Major Histocompatibility Complex (MHC) Class I Allele HLA-A*02:01: BREAKING CONFINEMENT.
J. Biol. Chem., 292, 2017
4I9X
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BU of 4i9x by Molmil
Crystal structure of human cytomegalovirus glycoprotein UL141 targeting the death receptor TRAIL-R2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Nemcovicova, I, Zajonc, D.M.
登録日2012-12-05
公開日2013-04-03
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of Human Cytomegalovirus UL141 Binding to TRAIL-R2 Reveals Novel, Non-canonical Death Receptor Interactions.
Plos Pathog., 9, 2013
5T2Q
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Unliganded Human HVEM at 1.9A in P 1 21 1
分子名称: Tumor necrosis factor receptor superfamily member 14
著者Nemcovicova, I, Zajonc, D.M.
登録日2016-08-24
公開日2018-10-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Unliganded Human HVEM at 1.9A in P 1 21 1
To Be Published
5T2R
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Unliganded Human HVEM at 2.1A in P 21 21 21
分子名称: Tumor necrosis factor receptor superfamily member 14
著者Nemcovicova, I, Zajonc, D.M.
登録日2016-08-24
公開日2018-10-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Unliganded Human HVEM at 2.1A in P 21 21 21
To Be Published
6O53
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Structure of HLA-A2:01 with peptide MM96
分子名称: Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ...
著者Ying, G, Bitra, A, Zajonc, D.M.
登録日2019-03-01
公開日2020-01-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Anin silico-in vitroPipeline Identifying an HLA-A*02:01+KRAS G12V+Spliced Epitope Candidate for a Broad Tumor-Immune Response in Cancer Patients.
Front Immunol, 10, 2019
6OOR
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BU of 6oor by Molmil
Structure of 1B1 bound to mouse CD1d
分子名称: Antibody 1B1 Heavy chain, Antibody 1B1 Light chain, Antigen-presenting glycoprotein CD1d1, ...
著者Ying, G, Zajonc, D.M.
登録日2019-04-23
公開日2019-07-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural basis of NKT cell inhibition using the T-cell receptor-blocking anti-CD1d antibody 1B1.
J.Biol.Chem., 294, 2019
6O4Y
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Structure of HLA-A2:01 with peptide MM91
分子名称: Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ...
著者Ying, G, Bitra, A, Zajonc, D.M.
登録日2019-03-01
公開日2020-01-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Anin silico-in vitroPipeline Identifying an HLA-A*02:01+KRAS G12V+Spliced Epitope Candidate for a Broad Tumor-Immune Response in Cancer Patients.
Front Immunol, 10, 2019
2FIK
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BU of 2fik by Molmil
Structure of a microbial glycosphingolipid bound to mouse CD1d
分子名称: (2S,3R)-3-HYDROXY-2-(TETRADECANOYLAMINO)OCTADECYL ALPHA-D-GALACTOPYRANOSIDURONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Wu, D, Zajonc, D.M.
登録日2005-12-29
公開日2006-03-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Design of natural killer T cell activators: structure and function of a microbial glycosphingolipid bound to mouse CD1d.
Proc.Natl.Acad.Sci.Usa, 103, 2006
3JVG
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BU of 3jvg by Molmil
Crystal Structure of chicken CD1-1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, CHLORIDE ION, ...
著者Dvir, H, Wang, J, Zajonc, D.M.
登録日2009-09-16
公開日2010-02-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for lipid-antigen recognition in avian immunity.
J.Immunol., 184, 2010
4IRS
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BU of 4irs by Molmil
Structure of the mouse CD1d-PyrC-alpha-GalCer-iNKT TCR complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Nemcovic, M, Zajonc, D.M.
登録日2013-01-15
公開日2013-09-04
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Enhanced TCR footprint by a novel glycolipid increases NKT-dependent tumor protection.
J.Immunol., 191, 2013
4JM0
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Structure of Human Cytomegalovirus Immune Modulator UL141
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Protein UL141
著者Nemcovicova, I, Zajonc, D.M.
登録日2013-03-13
公開日2014-02-26
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献The structure of cytomegalovirus immune modulator UL141 highlights structural Ig-fold versatility for receptor binding.
Acta Crystallogr.,Sect.D, 70, 2014
4LU5
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Structure of murine IgG2a A20G2-Fab in complex with vaccinia antigen A33R at the resolution of 2.9 Angstroms
分子名称: A33R, Murine IgG2a A20G2 Heavy chain Fab domain, Murine IgG2a A20G2 Light chain Fab domain
著者Matho, M.H, Schlossman, A.M, Zajonc, D.M.
登録日2013-07-24
公開日2014-07-30
最終更新日2015-09-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural and Functional Characterization of Anti-A33 Antibodies Reveal a Potent Cross-Species Orthopoxviruses Neutralizer.
Plos Pathog., 11, 2015
4M1G
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Structure of murine IgG2a A27D7-Fab in complex with vaccinia antigen A33R at the resolution of 1.6 Angstroms
分子名称: A33R, Murine IgG2a A27D7 Heavy chain Fab domain, Murine IgG2a A27D7 Light chain Fab domain, ...
著者Matho, M.H, Schlossman, A.M, Zajonc, D.M.
登録日2013-08-02
公開日2014-08-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural and Functional Characterization of Anti-A33 Antibodies Reveal a Potent Cross-Species Orthopoxviruses Neutralizer.
Plos Pathog., 11, 2015
4LQF
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BU of 4lqf by Molmil
Structure of murine IgG2b A2C7-Fab in complex with vaccinia antigen A33R at the resolution of 2.3 Angstroms
分子名称: A33R, Murine IgG2b A2C7 Heavy chain Fab domain, Murine IgG2b A2C7 Light chain Fab domain, ...
著者Matho, M.H, Schlossman, A.M, Zajonc, D.M.
登録日2013-07-17
公開日2014-08-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Functional Characterization of Anti-A33 Antibodies Reveal a Potent Cross-Species Orthopoxviruses Neutralizer.
Plos Pathog., 11, 2015
4IRJ
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Structure of the mouse CD1d-4ClPhC-alpha-GalCer-iNKT TCR complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
著者Nemcovic, M, Zajonc, D.M.
登録日2013-01-14
公開日2013-08-28
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Enhanced TCR footprint by a novel glycolipid increases NKT-dependent tumor protection.
J.Immunol., 191, 2013
4E9O
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BU of 4e9o by Molmil
Vaccinia D8L ectodomain structure
分子名称: IMV membrane protein, IODIDE ION
著者Matho, M.H, Zajonc, D.M.
登録日2012-03-21
公開日2012-06-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Structural and Biochemical Characterization of the Vaccinia Virus Envelope Protein D8 and Its Recognition by the Antibody LA5.
J.Virol., 86, 2012
4ETQ
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BU of 4etq by Molmil
Vaccinia virus D8L IMV envelope protein in complex with Fab of murine IgG2a LA5
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ...
著者Matho, M.H, Zajonc, D.M.
登録日2012-04-24
公開日2012-06-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and Biochemical Characterization of the Vaccinia Virus Envelope Protein D8 and Its Recognition by the Antibody LA5.
J.Virol., 86, 2012

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