7YNL
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![BU of 7ynl by Molmil](/molmil-images/mine/7ynl) | EB-bound alpha-synuclein fibrils | Descriptor: | 4-azanyl-6-[[4-[4-[(~{E})-(8-azanyl-1-oxidanyl-5,7-disulfo-naphthalen-2-yl)diazenyl]-3-methyl-phenyl]-2-methyl-phenyl]diazenyl]-5-oxidanyl-naphthalene-1,3-disulfonic acid, Alpha-synuclein | Authors: | Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D. | Deposit date: | 2022-07-31 | Release date: | 2023-08-02 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | EB-bound alpha-synuclein fibrils To Be Published
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7F1R
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![BU of 7f1r by Molmil](/molmil-images/mine/7f1r) | Cryo-EM structure of the chemokine receptor CCR5 in complex with RANTES and Gi | Descriptor: | C-C motif chemokine 5,C-C chemokine receptor type 5, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Zhang, H, Chen, K, Tan, Q, Han, S, Zhu, Y, Zhao, Q, Wu, B. | Deposit date: | 2021-06-09 | Release date: | 2021-07-14 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis for chemokine recognition and receptor activation of chemokine receptor CCR5. Nat Commun, 12, 2021
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7F1T
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![BU of 7f1t by Molmil](/molmil-images/mine/7f1t) | Crystal structure of the human chemokine receptor CCR5 in complex with MIP-1a | Descriptor: | C-C motif chemokine 3,C-C chemokine receptor type 5,Rubredoxin,C-C chemokine receptor type 5, ZINC ION | Authors: | Zhang, H, Chen, K, Tan, Q, Han, S, Zhu, Y, Zhao, Q, Wu, B. | Deposit date: | 2021-06-09 | Release date: | 2021-07-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for chemokine recognition and receptor activation of chemokine receptor CCR5. Nat Commun, 12, 2021
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7F1S
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![BU of 7f1s by Molmil](/molmil-images/mine/7f1s) | Cryo-EM structure of the apo chemokine receptor CCR5 in complex with Gi | Descriptor: | C-C chemokine receptor type 5, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Zhang, H, Chen, K, Tan, Q, Han, S, Zhu, Y, Zhao, Q, Wu, B. | Deposit date: | 2021-06-09 | Release date: | 2021-07-14 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural basis for chemokine recognition and receptor activation of chemokine receptor CCR5. Nat Commun, 12, 2021
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7F1Q
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![BU of 7f1q by Molmil](/molmil-images/mine/7f1q) | Cryo-EM structure of the chemokine receptor CCR5 in complex with MIP-1a and Gi | Descriptor: | C-C motif chemokine 3,C-C chemokine receptor type 5, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Zhang, H, Chen, K, Tan, Q, Han, S, Zhu, Y, Zhao, Q, Wu, B. | Deposit date: | 2021-06-09 | Release date: | 2021-07-14 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis for chemokine recognition and receptor activation of chemokine receptor CCR5. Nat Commun, 12, 2021
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7EZH
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![BU of 7ezh by Molmil](/molmil-images/mine/7ezh) | Cryo-EM structure of an activated Cholecystokinin A receptor (CCKAR)-Gi complex | Descriptor: | Cholecystokinin receptor type A, Cholecystokinin-8, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Liu, Q.F, Yang, D.H, Zhuang, Y.W, Croll, T.I, Cai, X.Q, Duan, J, Dai, A.T, Yin, W.C, Ye, C.Y, Zhou, F.L, Wu, B.L, Zhao, Q, Xu, H.E, Wang, M.W, Jiang, Y. | Deposit date: | 2021-06-01 | Release date: | 2021-08-25 | Last modified: | 2022-06-29 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor Nat.Chem.Biol., 17, 2021
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7EZK
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![BU of 7ezk by Molmil](/molmil-images/mine/7ezk) | Cryo-EM structure of an activated Cholecystokinin A receptor (CCKAR)-Gs complex | Descriptor: | Chimera of Guanine nucleotide-binding protein G(i) subunit alpha-1 and Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Cholecystokinin receptor type A, Cholecystokinin-8, ... | Authors: | Liu, Q.F, Yang, D.H, Zhuang, Y.W, Croll, T.I, Cai, X.Q, Duan, J, Dai, A.T, Yin, W.C, Ye, C.Y, Zhou, F.L, Wu, B.L, Zhao, Q, Xu, H.E, Wang, M.W, Jiang, Y. | Deposit date: | 2021-06-01 | Release date: | 2021-08-25 | Last modified: | 2022-06-29 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor Nat.Chem.Biol., 17, 2021
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7XXI
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![BU of 7xxi by Molmil](/molmil-images/mine/7xxi) | Cryo-EM structure of the purinergic receptor P2Y12R in complex with 2MeSADP and Gi | Descriptor: | 2-(methylsulfanyl)adenosine 5'-(trihydrogen diphosphate), Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Tan, Q, Li, B, Han, S, Zhao, Q, Wu, B. | Deposit date: | 2022-05-30 | Release date: | 2023-06-07 | Last modified: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural insights into signal transduction of the purinergic receptors P2Y1R and P2Y12R. Protein Cell, 14, 2023
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7XXH
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![BU of 7xxh by Molmil](/molmil-images/mine/7xxh) | Cryo-EM structure of the purinergic receptor P2Y1R in complex with 2MeSADP and G11 | Descriptor: | 2-(methylsulfanyl)adenosine 5'-(trihydrogen diphosphate), Guanine nucleotide-binding protein G(11) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Tan, Q, Li, B, Han, S, Zhao, Q, Wu, B. | Deposit date: | 2022-05-30 | Release date: | 2023-06-07 | Last modified: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural insights into signal transduction of the purinergic receptors P2Y1R and P2Y12R. Protein Cell, 14, 2023
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7WMM
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![BU of 7wmm by Molmil](/molmil-images/mine/7wmm) | alpha-synuclein fibril-F0502B complex | Descriptor: | 2-bromanyl-4-[(~{E})-2-[6-[2-(2-fluoranylethoxy)ethyl-methyl-amino]-5-methyl-1,3-benzothiazol-2-yl]ethenyl]phenol, Alpha-synuclein | Authors: | Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D. | Deposit date: | 2022-01-15 | Release date: | 2023-01-18 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | alpha-synuclein fibril-F0502B complex To Be Published
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7YNQ
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![BU of 7ynq by Molmil](/molmil-images/mine/7ynq) | |
7YNT
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![BU of 7ynt by Molmil](/molmil-images/mine/7ynt) | |
7YNM
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![BU of 7ynm by Molmil](/molmil-images/mine/7ynm) | ThT-bound alpha-synuclein fibrils conformation 1 | Descriptor: | 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium, Alpha-synuclein | Authors: | Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D. | Deposit date: | 2022-07-31 | Release date: | 2023-08-02 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | ThT-bound alpha-synuclein fibrils conformation 1 To Be Published
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7YNR
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![BU of 7ynr by Molmil](/molmil-images/mine/7ynr) | |
7YNP
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![BU of 7ynp by Molmil](/molmil-images/mine/7ynp) | BF227-bound alpha-synuclein fibrils | Descriptor: | 5-[(~{E})-2-(6-methoxy-1,3-benzoxazol-2-yl)ethenyl]-~{N},~{N}-dimethyl-1,3-thiazol-2-amine, Alpha-synuclein | Authors: | Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D. | Deposit date: | 2022-07-31 | Release date: | 2023-08-02 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | BF227-bound alpha-synuclein fibrils To Be Published
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7YNN
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![BU of 7ynn by Molmil](/molmil-images/mine/7ynn) | ThT-bound alpha-synuclein fibrils conformation 2 | Descriptor: | 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium, Alpha-synuclein | Authors: | Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D. | Deposit date: | 2022-07-31 | Release date: | 2023-08-02 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | ThT-bound alpha-synuclein fibrils conformation 2 To Be Published
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7YNO
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![BU of 7yno by Molmil](/molmil-images/mine/7yno) | |
7YNG
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![BU of 7yng by Molmil](/molmil-images/mine/7yng) | |
7YNS
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![BU of 7yns by Molmil](/molmil-images/mine/7yns) | |
7YNF
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![BU of 7ynf by Molmil](/molmil-images/mine/7ynf) | CCA-bound alpha-synuclein fibrils | Descriptor: | Alpha-synuclein, copper;trisodium;18-(2-carboxylatoethyl)-20-(carboxylatomethyl)-12-ethenyl-7-ethyl-3,8,13,17-tetramethyl-17,18-dihydroporphyrin-21,23-diide-2-carboxylate | Authors: | Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D. | Deposit date: | 2022-07-30 | Release date: | 2023-12-06 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | CCA-bound alpha-synuclein fibrils To Be Published
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7WVY
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![BU of 7wvy by Molmil](/molmil-images/mine/7wvy) | Cryo-EM structure of the human formyl peptide receptor 2 in complex with Abeta42 and Gi2 | Descriptor: | Amyloid-beta A4 protein, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Zhu, Y, Lin, X, Zong, X, Han, S, Zhao, Q, Wu, B. | Deposit date: | 2022-02-11 | Release date: | 2022-04-13 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis of FPR2 in recognition of A beta 42 and neuroprotection by humanin. Nat Commun, 13, 2022
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7WVW
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![BU of 7wvw by Molmil](/molmil-images/mine/7wvw) | Cryo-EM structure of the human formyl peptide receptor 2 in complex with fMYFINILTL and Gi2 | Descriptor: | FME-TYR-PHE-ILE-ASN-ILE-LEU-THE-LEU, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Zhu, Y, Lin, X, Zong, X, Han, S, Zhao, Q, Wu, B. | Deposit date: | 2022-02-11 | Release date: | 2022-04-13 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis of FPR2 in recognition of A beta 42 and neuroprotection by humanin. Nat Commun, 13, 2022
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7WVU
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![BU of 7wvu by Molmil](/molmil-images/mine/7wvu) | Cryo-EM structure of the human formyl peptide receptor 1 in complex with fMLF and Gi1 | Descriptor: | FME-LEU-PHE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Zhu, Y, Lin, X, Zong, X, Han, S, Zhao, Q, Wu, B. | Deposit date: | 2022-02-11 | Release date: | 2022-04-13 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis of FPR2 in recognition of A beta 42 and neuroprotection by humanin. Nat Commun, 13, 2022
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7WVV
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![BU of 7wvv by Molmil](/molmil-images/mine/7wvv) | Cryo-EM structure of the human formyl peptide receptor 2 in complex with fMLFII and Gi2 | Descriptor: | FME-LEU-PHE-ILE-ILE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Zhu, Y, Lin, X, Zong, X, Han, S, Zhao, Q, Wu, B. | Deposit date: | 2022-02-11 | Release date: | 2022-04-13 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis of FPR2 in recognition of A beta 42 and neuroprotection by humanin. Nat Commun, 13, 2022
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7WVX
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![BU of 7wvx by Molmil](/molmil-images/mine/7wvx) | Cryo-EM structure of the human formyl peptide receptor 2 in complex with fhumanin and Gi2 | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-2, ... | Authors: | Zhu, Y, Lin, X, Zong, X, Han, S, Zhao, Q, Wu, B. | Deposit date: | 2022-02-11 | Release date: | 2022-04-13 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural basis of FPR2 in recognition of A beta 42 and neuroprotection by humanin. Nat Commun, 13, 2022
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