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PDB: 21 件
8JYE
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BU of 8jye by Molmil
Crystal Structure of Intracellular B30.2 Domain of BTN3A1 and BTN2A1 in Complex with HMBPP
分子名称: (2E)-4-hydroxy-3-methylbut-2-en-1-yl trihydrogen diphosphate, 1,2-ETHANEDIOL, Butyrophilin subfamily 2 member A1, ...
著者Yuan, L.J, Yang, Y.Y, Li, X, Cai, N.N, Chen, C.-C, Guo, R.-T, Zhang, Y.H.
登録日2023-07-03
公開日2023-09-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells.
Nature, 621, 2023
8JYC
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BU of 8jyc by Molmil
Crystal Structure of Intracellular B30.2 Domain of BTN3A1 and BTN2A1 in Complex with DMAPP
分子名称: 1,2-ETHANEDIOL, Butyrophilin subfamily 2 member A1, Butyrophilin subfamily 3 member A1, ...
著者Yuan, L.J, Yang, Y.Y, Li, X, Cai, N.N, Chen, C.-C, Guo, R.-T, Zhang, Y.H.
登録日2023-07-03
公開日2023-09-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells.
Nature, 621, 2023
7K5J
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BU of 7k5j by Molmil
Structure of an E1-E2-ubiquitin thioester mimetic
分子名称: ADENOSINE MONOPHOSPHATE, Ubiquitin, Ubiquitin-activating enzyme E1 1, ...
著者Yuan, L, Lv, Z, Olsen, S.K.
登録日2020-09-16
公開日2021-04-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.42 Å)
主引用文献Crystal structures of an E1-E2-ubiquitin thioester mimetic reveal molecular mechanisms of transthioesterification.
Nat Commun, 12, 2021
5TTE
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BU of 5tte by Molmil
Crystal Structure of an RBR E3 ubiquitin ligase in complex with an E2-Ub thioester intermediate mimic
分子名称: E3 ubiquitin-protein ligase ARIH1, Ubiquitin-conjugating enzyme E2 L3, ZINC ION, ...
著者Yuan, L, Lv, Z, Olsen, S.K.
登録日2016-11-03
公開日2017-08-23
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.501 Å)
主引用文献Structural insights into the mechanism and E2 specificity of the RBR E3 ubiquitin ligase HHARI.
Nat Commun, 8, 2017
8IGT
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BU of 8igt by Molmil
Crystal Structure of Intracellular B30.2 Domain of BTN2A1
分子名称: Butyrophilin subfamily 2 member A1, ZINC ION
著者Yuan, L.J, Yang, Y.Y, Li, X, Cai, N.N, Chen, C.C, Guo, R.T, Zhang, Y.H.
登録日2023-02-21
公開日2023-09-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells.
Nature, 621, 2023
8X6G
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BU of 8x6g by Molmil
Cryo-EM structure of Staphylococcus aureus sigB-dependent RNAP-promoter open complex
分子名称: DNA (70-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Yuan, L, Xu, L, Liu, Q, Feng, Y.
登録日2023-11-21
公開日2024-06-05
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis of promoter recognition by Staphylococcus aureus RNA polymerase.
Nat Commun, 15, 2024
8X6F
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BU of 8x6f by Molmil
Cryo-EM structure of Staphylococcus aureus sigA-dependent RNAP-promoter open complex
分子名称: DNA (71-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Yuan, L, Xu, L, Liu, Q, Feng, Y.
登録日2023-11-21
公開日2024-06-05
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis of promoter recognition by Staphylococcus aureus RNA polymerase.
Nat Commun, 15, 2024
3J9B
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BU of 3j9b by Molmil
Electron cryo-microscopy of an RNA polymerase
分子名称: Polymerase, Polymerase basic protein 2, RNA (5'-R(*UP*UP*UP*UP*UP*A)-3'), ...
著者Chang, S.H, Sun, D.P, Liang, H.H, Wang, J, Li, J, Guo, L, Wang, X.L, Guan, C.C, Boruah, B.M, Yuan, L.M, Feng, F, Yang, M.R, Wojdyla, J, Wang, J.W, Wang, M.T, Wang, H.W, Liu, Y.F.
登録日2014-12-16
公開日2015-02-18
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Cryo-EM Structure of Influenza Virus RNA Polymerase Complex at 4.3 angstrom Resolution.
Mol.Cell, 2015
8PO7
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BU of 8po7 by Molmil
Structure of Escherichia coli HrpA in complex with ADP and dinucleotide dCdC
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase HrpA, DNA (5'-D(P*CP*C)-3'), ...
著者Xin, B.G, Yuan, L.G, Zhang, L.L, Xie, S.M, Liu, N.N, Ai, X, Li, H.H, Rety, S, Xi, X.G.
登録日2023-07-03
公開日2024-05-08
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Structural insights into the N-terminal APHB domain of HrpA: mediating canonical and i-motif recognition.
Nucleic Acids Res., 52, 2024
8PO8
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BU of 8po8 by Molmil
Structure of Escherichia coli HrpA in complex with ADP and oligonucleotide poly(dC)11 forming an i-motif
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase HrpA, DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*C)-3'), ...
著者Xin, B.G, Yuan, L.G, Zhang, L.L, Xie, S.M, Liu, N.N, Ai, X, Li, H.H, Rety, S, Xi, X.G.
登録日2023-07-03
公開日2024-05-08
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Structural insights into the N-terminal APHB domain of HrpA: mediating canonical and i-motif recognition.
Nucleic Acids Res., 52, 2024
8PO6
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BU of 8po6 by Molmil
Structure of Escherichia coli HrpA apo form
分子名称: ATP-dependent RNA helicase HrpA, PHOSPHATE ION
著者Xin, B.G, Yuan, L.G, Zhang, L.L, Xie, S.M, Liu, N.N, Ai, X, Li, H.H, Rety, S, Xi, X.G.
登録日2023-07-03
公開日2024-05-08
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Structural insights into the N-terminal APHB domain of HrpA: mediating canonical and i-motif recognition.
Nucleic Acids Res., 52, 2024
5KNL
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BU of 5knl by Molmil
Crystal structure of S. pombe ubiquitin E1 (Uba1) in complex with Ubc15 and ubiquitin
分子名称: SULFATE ION, Ubiquitin, Ubiquitin-activating enzyme E1 1, ...
著者Olsen, S.K, Lv, Z, Yuan, L, Williams, K.
登録日2016-06-28
公開日2017-02-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献S. pombe Uba1-Ubc15 Structure Reveals a Novel Regulatory Mechanism of Ubiquitin E2 Activity.
Mol. Cell, 65, 2017
6CWY
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BU of 6cwy by Molmil
Crystal structure of SUMO E1 in complex with an allosteric inhibitor
分子名称: GLYCEROL, MAGNESIUM ION, SULFATE ION, ...
著者Lv, Z, Yuan, L, Atkison, J.H, Williams, K.M, Olsen, S.K.
登録日2018-04-01
公開日2019-01-16
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.462 Å)
主引用文献Molecular mechanism of a covalent allosteric inhibitor of SUMO E1 activating enzyme.
Nat Commun, 9, 2018
4RZE
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BU of 4rze by Molmil
Crystal Structure Analysis of the NUR77 Ligand Binding Domain, L437W,D594E mutant
分子名称: GLYCEROL, Nuclear receptor subfamily 4 group A member 1
著者Fengwei, L, Xuyang, T, Anzhong, L, Li, L, Yuan, L, Hangzi, C, Qiao, W, Tianwei, L.
登録日2014-12-21
公開日2015-03-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation.
Nat.Chem.Biol., 11, 2015
6CWZ
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BU of 6cwz by Molmil
Crystal structure of apo SUMO E1
分子名称: SUMO-activating enzyme subunit 1, SUMO-activating enzyme subunit 2, ZINC ION
著者Lv, Z, Yuan, L, Atkison, J.H, Williams, K.M, Olsen, S.K.
登録日2018-04-01
公開日2019-01-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Molecular mechanism of a covalent allosteric inhibitor of SUMO E1 activating enzyme.
Nat Commun, 9, 2018
6DC6
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BU of 6dc6 by Molmil
Crystal structure of human ubiquitin activating enzyme E1 (Uba1) in complex with ubiquitin
分子名称: MAGNESIUM ION, PYROPHOSPHATE 2-, Ubiquitin, ...
著者Lv, Z, Yuan, L, Williams, K.M, Atkison, J.H, Olsen, S.K.
登録日2018-05-04
公開日2018-10-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.14 Å)
主引用文献Crystal structure of a human ubiquitin E1-ubiquitin complex reveals conserved functional elements essential for activity.
J. Biol. Chem., 293, 2018
5UM6
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BU of 5um6 by Molmil
Crystal Structure of S. pombe Uba1 in a closed conformation
分子名称: 2-(decylamino)ethane-1-thiol, N-(2-{[(4-chlorophenyl)methyl]disulfanyl}ethyl)decan-1-amine, SULFATE ION, ...
著者Lv, Z, Yuan, L, Aldana-Masangkay, G, Atkison, J.H, Chen, Y, Olsen, S.K.
登録日2017-01-26
公開日2017-06-14
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.794 Å)
主引用文献Domain alternation and active site remodeling are conserved structural features of ubiquitin E1.
J. Biol. Chem., 292, 2017
4J0U
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BU of 4j0u by Molmil
Crystal structure of IFIT5/ISG58
分子名称: Interferon-induced protein with tetratricopeptide repeats 5
著者Liu, Y, Liang, H, Feng, F, Yuan, L, Wang, Y.E, Crowley, C, Lv, Z, Li, J, Zeng, S, Cheng, G.
登録日2013-01-31
公開日2013-02-13
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.969 Å)
主引用文献Crystal Structure of IFIT5
To be Published
5YZV
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BU of 5yzv by Molmil
Biophysical and structural characterization of the thermostable WD40 domain of a prokaryotic protein, Thermomonospora curvata PkwA
分子名称: Probable serine/threonine-protein kinase PkwA
著者Li, D.Y, Shen, C, Du, Y, Qiao, F.F, Kong, T, Yuan, L.R, Zhang, D.L, Wu, X.H, Wu, Y.D.
登録日2017-12-15
公開日2018-10-03
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Biophysical and structural characterization of the thermostable WD40 domain of a prokaryotic protein, Thermomonospora curvata PkwA
Sci Rep, 8, 2018
8ISS
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BU of 8iss by Molmil
Cryo-EM structure of wild-type human tRNA Splicing Endonuclease Complex bound to pre-tRNA-ARG at 3.19 A resolution
分子名称: MAGNESIUM ION, RNA (88-MER), tRNA-splicing endonuclease subunit Sen15, ...
著者Sun, Y, Zhang, Y, Yuan, L, Han, Y.
登録日2023-03-21
公開日2023-10-18
実験手法ELECTRON MICROSCOPY (3.19 Å)
主引用文献Recognition and cleavage mechanism of intron-containing pre-tRNA by human TSEN endonuclease complex.
Nat Commun, 14, 2023
5XHQ
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BU of 5xhq by Molmil
Apolipoprotein N-acyl Transferase
分子名称: Apolipoprotein N-acyltransferase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Yingzhi, X, Yong, X, Guangyuan, L, Fei, S.
登録日2017-04-23
公開日2017-07-26
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.587 Å)
主引用文献Crystal structure of E. coli apolipoprotein N-acyl transferase
Nat Commun, 8, 2017

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