5XZO
 
 | | Crystal structure of GH10 xylanase XYL10C from Bispora. sp MEY-1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-xylanase | | 著者 | You, S, Chen, C, Tu, T, Guo, R.T, Luo, H, Yao, B. | | 登録日 | 2017-07-13 | | 公開日 | 2018-01-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal structure of GH10 xylanase XYL10C from Bispora. sp MEY-1
To Be Published
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5XZU
 | | Crystal structure of GH10 xylanase from Bispora. sp MEY-1 with xylobiose | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-xylanase, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | | 著者 | You, S, Chen, C.C, Tu, T, Guo, R.T, Luo, H.Y, Yao, B. | | 登録日 | 2017-07-14 | | 公開日 | 2018-05-02 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Insight into the functional roles of Glu175 in the hyperthermostable xylanase XYL10C-Delta N through structural analysis and site-saturation mutagenesis.
Biotechnol Biofuels, 11, 2018
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5H7D
 | | Crystal structure of the YgjG-protein A-Zpa963-calmodulin complex | | 分子名称: | CALCIUM ION, Putrescine aminotransferase,Immunoglobulin G-binding protein A, Zpa963,Calmodulin | | 著者 | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | | 登録日 | 2016-11-17 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method.
Sci Rep, 7, 2017
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5X3F
 | | Crystal structure of the YgjG-Protein A-Zpa963-PKA catalytic domain | | 分子名称: | Putrescine aminotransferase,Immunoglobulin G-binding protein A, Zpa963,cAMP-dependent protein kinase catalytic subunit alpha | | 著者 | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | | 登録日 | 2017-02-05 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.38 Å) | | 主引用文献 | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method.
Sci Rep, 7, 2017
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5H7A
 | | Crystal structure of a repeat protein with four Protein A repeat module | | 分子名称: | Immunoglobulin G-binding protein A | | 著者 | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | | 登録日 | 2016-11-17 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method.
Sci Rep, 7, 2017
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5H75
 | | Crystal structure of the MrsD-Protein A fusion protein | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Mersacidin decarboxylase,Immunoglobulin G-binding protein A | | 著者 | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | | 登録日 | 2016-11-17 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.738 Å) | | 主引用文献 | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method.
Sci Rep, 7, 2017
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5H7B
 | | Crystal structure of a repeat protein with five Protein A repeat modules | | 分子名称: | Immunoglobulin G-binding protein A | | 著者 | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | | 登録日 | 2016-11-17 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method.
Sci Rep, 7, 2017
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5H79
 | | Crystal structure of a repeat protein with three Protein A repeat module | | 分子名称: | Immunoglobulin G-binding protein A | | 著者 | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | | 登録日 | 2016-11-17 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method.
Sci Rep, 7, 2017
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5H78
 | | Crystal structure of the PKA-DHR14 fusion protein | | 分子名称: | cAMP-dependent protein kinase type II-alpha regulatory subunit,DHR14 | | 著者 | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | | 登録日 | 2016-11-17 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.002 Å) | | 主引用文献 | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method.
Sci Rep, 7, 2017
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5H7C
 | | Crystal structure of a repeat protein with two Protein A-DHR14 repeat modules | | 分子名称: | Immunoglobulin G-binding protein A, DHR14 | | 著者 | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | | 登録日 | 2016-11-17 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method.
Sci Rep, 7, 2017
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5H76
 | | Crystal structure of the DARPin-Protein A fusion protein | | 分子名称: | DARPin,Immunoglobulin G-binding protein A | | 著者 | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | | 登録日 | 2016-11-17 | | 公開日 | 2017-06-28 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method.
Sci Rep, 7, 2017
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5XBY
 | | Crystal structure of the PKA-Protein A fusion protein (end-to-end fusion) | | 分子名称: | cAMP-dependent protein kinase type II-alpha regulatory subunit,Immunoglobulin G-binding protein A | | 著者 | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | | 登録日 | 2017-03-21 | | 公開日 | 2017-07-05 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method.
Sci Rep, 7, 2017
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5H77
 | | Crystal structure of the PKA-protein A fusion protein | | 分子名称: | cAMP-dependent protein kinase type II-alpha regulatory subunit,Immunoglobulin G-binding protein A | | 著者 | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | | 登録日 | 2016-11-17 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.197 Å) | | 主引用文献 | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method.
Sci Rep, 7, 2017
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8Y83
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8Y7R
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7A9E
 | | tRNA-guanine transglycosylase C158S/C281S/Y330C/H333A mutant in complex with ethyl methyl sulfone | | 分子名称: | 1,2-ETHANEDIOL, 1-methylsulfonylethane, GLYCEROL, ... | | 著者 | Nguyen, D, You, S, Heine, A, Klebe, G. | | 登録日 | 2020-09-01 | | 公開日 | 2021-06-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Targeting a Cryptic Pocket in a Protein-Protein Contact by Disulfide-Induced Rupture of a Homodimeric Interface.
Acs Chem.Biol., 16, 2021
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7ADN
 | | apo tRNA-guanine transglycosylase C158S/C281S/Y330C/H333A mutant | | 分子名称: | FORMIC ACID, GLYCEROL, Queuine tRNA-ribosyltransferase, ... | | 著者 | Nguyen, D, You, S, Heine, A, Klebe, G. | | 登録日 | 2020-09-15 | | 公開日 | 2021-06-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Targeting a Cryptic Pocket in a Protein-Protein Contact by Disulfide-Induced Rupture of a Homodimeric Interface.
Acs Chem.Biol., 16, 2021
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5B6K
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1EB2
 | | Trypsin inhibitor complex (BPO) | | 分子名称: | 3-[(Z)-AMINO(IMINO)METHYL]-N-[2-(4-BENZOYL-1-PIPERIDINYL)-2-OXO-1-PHENYLETHYL]BENZAMIDE, CALCIUM ION, SULFATE ION, ... | | 著者 | Wilkinson, K.W, Young, S.C, Liebeschuetz, J.W, Brady, R.L. | | 登録日 | 2001-07-18 | | 公開日 | 2002-02-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Pro_Select: Combining Structure-Based Drug Design and Array-Based Chemistry for Rapid Lead Discovery. 2. The Development of a Series of Highly Potent and Selective Factor Xa Inhibitors
J.Med.Chem., 45, 2002
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4B6L
 | | Discovery of Oral Polo-Like Kinase (PLK) Inhibitors with Enhanced Selectivity Profile using Residue Targeted Drug Design | | 分子名称: | 4-[[(4R)-5-cyclopentyl-4-ethyl-3a,4-dihydro-3H-[1,2,4]triazolo[4,3-f]pteridin-7-yl]amino]-N-cyclopropyl-3-methoxy-benzamide, SERINE/THREONINE-PROTEIN KINASE PLK3, SULFATE ION | | 著者 | Brown, K, Charrier, J.D, Durrant, S, Griffiths, M, Hudson, C, Kay, D, Knegtel, R, ODonnell, M, Pierard, F, Twin, H, Weber, P, Young, S. | | 登録日 | 2012-08-14 | | 公開日 | 2013-08-21 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Discovery of Oral Polo-Like Kinase (Plk) Inhibitors with Enhanced Selectivity Profile Using Residue Targeted Drug Design
To be Published
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5GS1
 | | Crystal structure of homo-specific diabody | | 分子名称: | diabody, heavy chain, light chain | | 著者 | Kim, J.H, Song, D.H, Youn, S.J, Kim, J.W, Cho, G, Lee, H, Lee, J.O. | | 登録日 | 2016-08-13 | | 公開日 | 2016-10-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of mono- and bi-specific diabodies and reduction of their structural flexibility by introduction of disulfide bridges at the Fv interface.
Sci Rep, 6, 2016
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5GS0
 | | Crystal structure of the complex of TLR3 and bi-specific diabody | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor 3, alpha-D-mannopyranose, ... | | 著者 | Kim, J.H, Song, D.H, Youn, S.J, Kim, J.W, Cho, G, Lee, H, Lee, J.O. | | 登録日 | 2016-08-13 | | 公開日 | 2016-10-12 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.275 Å) | | 主引用文献 | Crystal structure of mono- and bi-specific diabodies and reduction of their structural flexibility by introduction of disulfide bridges at the Fv interface.
Sci Rep, 6, 2016
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5GS2
 | | Crystal structure of diabody complex with repebody and MBP | | 分子名称: | Maltose-binding periplasmic protein, anti-MBP, anti-repebody, ... | | 著者 | Kim, J.H, Song, D.H, Youn, S.J, Kim, J.W, Cho, G, Lee, H, Lee, J.O. | | 登録日 | 2016-08-13 | | 公開日 | 2016-10-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.592 Å) | | 主引用文献 | Crystal structure of mono- and bi-specific diabodies and reduction of their structural flexibility by introduction of disulfide bridges at the Fv interface.
Sci Rep, 6, 2016
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6WN4
 | | Structural basis for the binding of monoclonal antibody 5D2 to the tryptophan-rich lipid-binding loop in lipoprotein lipase | | 分子名称: | 5D2 FAB HEAVY CHAIN, 5D2 FAB LIGHT CHAIN, Lipoprotein lipase peptide | | 著者 | Luz, J.G, Birrane, G, Young, S.G, Meiyappan, M, Ploug, M. | | 登録日 | 2020-04-22 | | 公開日 | 2020-07-29 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The structural basis for monoclonal antibody 5D2 binding to the tryptophan-rich loop of lipoprotein lipase.
J.Lipid Res., 61, 2020
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5GRY
 | | Crystal structure of disulfide-bonded diabody | | 分子名称: | diabody | | 著者 | Kim, J.H, Song, D.H, Youn, S.J, Kim, J.W, Cho, G, Lee, H, Lee, J.O. | | 登録日 | 2016-08-12 | | 公開日 | 2016-10-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.639 Å) | | 主引用文献 | Crystal structure of mono- and bi-specific diabodies and reduction of their structural flexibility by introduction of disulfide bridges at the Fv interface.
Sci Rep, 6, 2016
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