6PZI
| Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP only | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8 | 著者 | Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W. | 登録日 | 2019-07-31 | 公開日 | 2019-08-14 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM. Elife, 8, 2019
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6PZC
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6NZ0
| Cryo-EM structure of AAV-2 in complex with AAVR PKD domains 1 and 2 | 分子名称: | Capsid protein VP1, Dyslexia-associated protein KIAA0319-like protein, MAGNESIUM ION | 著者 | Meyer, N.L, Xie, Q, Davulcu, O, Yoshioka, C, Chapman, M.S. | 登録日 | 2019-02-12 | 公開日 | 2019-06-12 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Structure of the gene therapy vector, adeno-associated virus with its cell receptor, AAVR. Elife, 8, 2019
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5TWV
| Cryo-EM structure of the pancreatic ATP-sensitive K+ channel SUR1/Kir6.2 in the presence of ATP and glibenclamide | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11 | 著者 | Martin, G.M, Yoshioka, C, Chen, J.Z, Shyng, S.L. | 登録日 | 2016-11-14 | 公開日 | 2017-01-25 | 最終更新日 | 2019-12-25 | 実験手法 | ELECTRON MICROSCOPY (6.3 Å) | 主引用文献 | Cryo-EM structure of the ATP-sensitive potassium channel illuminates mechanisms of assembly and gating. Elife, 6, 2017
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6PZB
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6PZ9
| Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP and repaglinide | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11, ... | 著者 | Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W. | 登録日 | 2019-07-31 | 公開日 | 2019-08-14 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | 主引用文献 | Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM. Elife, 8, 2019
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6PZA
| Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP and glibenclamide | 分子名称: | 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | 著者 | Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W. | 登録日 | 2019-07-31 | 公開日 | 2019-08-14 | 最終更新日 | 2020-10-07 | 実験手法 | ELECTRON MICROSCOPY (3.74 Å) | 主引用文献 | Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM. Elife, 8, 2019
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1Z97
| Human Carbonic Anhydrase III: Structural and Kinetic Study of Catalysis and Proton Transfer. | 分子名称: | Carbonic anhydrase III, ZINC ION | 著者 | Duda, D.M, Tu, C, Fisher, S.Z, An, H, Yoshioka, C, Govindasamy, L, Laipis, P.J, Agbandje-McKenna, M, Silverman, D.N, McKenna, R. | 登録日 | 2005-03-31 | 公開日 | 2005-08-09 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Human Carbonic Anhydrase III: Structural and Kinetic Study of Catalysis and Proton Transfer Biochemistry, 44, 2005
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1Z93
| Human Carbonic Anhydrase III:Structural and Kinetic study of Catalysis and Proton Transfer. | 分子名称: | Carbonic anhydrase III, ZINC ION | 著者 | Duda, D.M, Tu, C, Fisher, S.Z, An, H, Yoshioka, C, Govindasamy, L, Laipis, P.J, Agbandje-McKenna, M, Silverman, D.N, McKenna, R. | 登録日 | 2005-03-31 | 公開日 | 2005-08-09 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Human Carbonic Anhydrase III: Structural and Kinetic Study of Catalysis and Proton Transfer Biochemistry, 44, 2005
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6BQN
| Cryo-EM structure of ENaC | 分子名称: | 10D4 fab, 7B1 fab, EGFP-SCNN1G chimera, ... | 著者 | Noreng, S, Bharadwaj, A, Posert, R, Yoshioka, C, Baconguis, I. | 登録日 | 2017-11-28 | 公開日 | 2018-10-10 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structure of the human epithelial sodium channel by cryo-electron microscopy. Elife, 7, 2018
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1LZV
| Site-Specific Mutant (Tyr7 replaced with His) of Human Carbonic Anhydrase II | 分子名称: | Carbonic Anhydrase II, ZINC ION | 著者 | Tu, C.K, Qian, M, An, H, Wadhwa, N.R, Duda, D.M, Yoshioka, C, Pathak, Y, McKenna, R, Laipis, P.J, Silverman, D.N. | 登録日 | 2002-06-11 | 公開日 | 2002-10-23 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Kinetic analysis of multiple proton shuttles in the active site of human carbonic anhydrase. J.Biol.Chem., 277, 2002
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6DW0
| Cryo-EM structure of the benzodiazepine-sensitive alpha1beta1gamma2S tri-heteromeric GABAA receptor in complex with GABA (Whole map) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, Gamma-aminobutyric acid receptor subunit alpha-1,Gamma-aminobutyric acid receptor subunit alpha-1, ... | 著者 | Phulera, S, Zhu, H, Yu, J, Yoshioka, C, Gouaux, E. | 登録日 | 2018-06-26 | 公開日 | 2018-08-08 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Cryo-EM structure of the benzodiazepine-sensitive alpha 1 beta 1 gamma 2S tri-heteromeric GABAAreceptor in complex with GABA. Elife, 7, 2018
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6DW1
| Cryo-EM structure of the benzodiazepine-sensitive alpha1beta1gamma2S tri-heteromeric GABAA receptor in complex with GABA (ECD map) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, Gamma-aminobutyric acid receptor subunit alpha-1,Gamma-aminobutyric acid receptor subunit alpha-1, ... | 著者 | Phulera, S, Zhu, H, Yu, J, Yoshioka, C, Gouaux, E. | 登録日 | 2018-06-26 | 公開日 | 2018-08-08 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Cryo-EM structure of the benzodiazepine-sensitive alpha 1 beta 1 gamma 2S tri-heteromeric GABAAreceptor in complex with GABA. Elife, 7, 2018
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6AVE
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6BAA
| Cryo-EM structure of the pancreatic beta-cell KATP channel bound to ATP and glibenclamide | 分子名称: | 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | 著者 | Martin, G.M, Yoshioka, C, Shyng, S.L. | 登録日 | 2017-10-12 | 公開日 | 2017-11-01 | 最終更新日 | 2019-12-25 | 実験手法 | ELECTRON MICROSCOPY (3.63 Å) | 主引用文献 | Anti-diabetic drug binding site in a mammalian KATPchannel revealed by Cryo-EM. Elife, 6, 2017
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6BFU
| Glycan shield and fusion activation of a deltacoronavirus spike glycoprotein fine-tuned for enteric infections | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein, ... | 著者 | Xiong, X, Tortorici, M.A, Snijder, S, Yoshioka, C, Walls, A.C, Li, W, Seattle Structural Genomics Center for Infectious Disease (SSGCID), McGuire, A.T, Rey, F.A, Bosch, B.J, Veesler, D. | 登録日 | 2017-10-27 | 公開日 | 2017-11-22 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Glycan Shield and Fusion Activation of a Deltacoronavirus Spike Glycoprotein Fine-Tuned for Enteric Infections. J. Virol., 92, 2018
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1RFQ
| Actin Crystal Dynamics: Structural Implications for F-actin Nucleation, Polymerization and Branching Mediated by the Anti-parallel Dimer | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Reutzel, R, Yoshioka, C, Govindasamy, L, Yarmola, E.G, Agbandje-McKenna, M, Bubb, M.R, McKenna, R. | 登録日 | 2003-11-10 | 公開日 | 2003-12-16 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Actin crystal dynamics: structural implications for F-actin nucleation, polymerization, and branching mediated by the anti-parallel dimer. J.Struct.Biol., 146, 2004
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7JMD
| Sheep Connexin-46 at 2.5 angstroms resolution, Lipid Class 1 | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction alpha-3 protein | 著者 | Flores, J.A, Haddad, B.G, Dolan, K.A, Myers, J.B, Yoshioka, C.C, Copperman, J, Zuckerman, D.M, Reichow, S.L. | 登録日 | 2020-07-31 | 公開日 | 2020-09-09 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 angstrom. Nat Commun, 11, 2020
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7JN0
| Sheep Connexin-46 at 2.5 angstroms resolution, Lipid Class 2 | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction alpha-3 protein | 著者 | Flores, J.A, Haddad, B.G, Dolan, K.A, Myers, J.A, Yoshioka, C.C, Copperman, J, Zuckerman, D.M, Reichow, S.L. | 登録日 | 2020-08-03 | 公開日 | 2020-09-09 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 angstrom. Nat Commun, 11, 2020
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7JM9
| Sheep Connexin-50 at 2.5 angstroms reoslution, Lipid Class 2 | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction alpha-8 protein | 著者 | Flores, J.A, Haddad, B.G, Dolan, K.A, Myers, J.A, Yoshioka, C.C, Copperman, J, Zuckerman, D.M, Reichow, S.L. | 登録日 | 2020-07-31 | 公開日 | 2020-09-09 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 angstrom. Nat Commun, 11, 2020
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7JLW
| Sheep Connexin-50 at 2.5 angstroms resolution, Lipid Class 1 | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction alpha-8 protein | 著者 | Flores, J.A, Haddad, B.G, Dolan, K.A, Myers, J.B, Yoshioka, C.C, Copperman, J, Zuckerman, D.M, Reichow, S.L. | 登録日 | 2020-07-30 | 公開日 | 2020-09-09 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 angstrom. Nat Commun, 11, 2020
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7JJP
| Sheep Connexin-50 at 1.9 angstroms resolution by CryoEM | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction alpha-8 protein | 著者 | Flores, J.A, Haddad, B.G, Dolan, K.D, Myers, J.B, Yoshioka, C.C, Copperman, J, Zuckerman, D.M, Reichow, S.L. | 登録日 | 2020-07-27 | 公開日 | 2020-09-09 | 実験手法 | ELECTRON MICROSCOPY (1.94 Å) | 主引用文献 | Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 angstrom. Nat Commun, 11, 2020
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7JN1
| Sheep Connexin-46 at 2.5 angstroms resolution, Lipid Class 3 | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction alpha-3 protein | 著者 | Flores, J.A, Haddad, B.G, Dolan, K.D, Myers, J.B, Yoshioka, C.C, Copperman, J, Zuckerman, D.M, Reichow, S.L. | 登録日 | 2020-08-03 | 公開日 | 2020-09-09 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 angstrom. Nat Commun, 11, 2020
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5KK2
| Architecture of fully occupied GluA2 AMPA receptor - TARP complex elucidated by single particle cryo-electron microscopy | 分子名称: | Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit | 著者 | Zhao, Y, Chen, S, Yoshioka, C, Baconguis, I, Gouaux, E. | 登録日 | 2016-06-20 | 公開日 | 2016-07-06 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (7.3 Å) | 主引用文献 | Architecture of fully occupied GluA2 AMPA receptor-TARP complex elucidated by cryo-EM. Nature, 536, 2016
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1RDW
| Actin Crystal Dynamics: Structural Implications for F-actin Nucleation, Polymerization and Branching Mediated by the Anti-parallel Dimer | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Reutzel, R, Yoshioka, C, Govindasamy, L, Yarmola, E.G, Agbandje-Mckenna, M, Bubb, M.R, Mckenna, R. | 登録日 | 2003-11-06 | 公開日 | 2003-12-16 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Actin crystal dynamics: structural implications for F-actin nucleation, polymerization, and branching mediated by the anti-parallel dimer. J.Struct.Biol., 146, 2004
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