8SZL
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![BU of 8szl by Molmil](/molmil-images/mine/8szl) | Human liver-type glutaminase (Apo form) | Descriptor: | Glutaminase liver isoform, mitochondrial | Authors: | Feng, S, Aplin, C, Nguyen, T.-T.T, Milano, S.K, Cerione, R.A. | Deposit date: | 2023-05-30 | Release date: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.12 Å) | Cite: | Filament formation drives catalysis by glutaminase enzymes important in cancer progression. Nat Commun, 15, 2024
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8F2R
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![BU of 8f2r by Molmil](/molmil-images/mine/8f2r) | Human CCC complex | Descriptor: | COMM domain-containing protein 1, COMM domain-containing protein 10, COMM domain-containing protein 2, ... | Authors: | Healy, M.D, McNally, K.E, Butkovic, R, Chilton, M, Kato, K, Sacharz, J, McConville, C, Moody, E.R.R, Shaw, S, Planelles-Herrero, V.J, Kadapalakere, S.Y, Ross, J, Borucu, U, Palmer, C.S, Chen, K, Croll, T.I, Hall, R.J, Caruana, N.J, Ghai, R, Nguyen, T.H.D, Heesom, K.J, Saitoh, S, Berger, I, Berger-Schaffitzel, C, Williams, T.A, Stroud, D.A, Derivery, E, Collins, B.M, Cullen, P.J. | Deposit date: | 2022-11-08 | Release date: | 2023-05-24 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.12 Å) | Cite: | Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome. Cell, 186, 2023
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7Y0G
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![BU of 7y0g by Molmil](/molmil-images/mine/7y0g) | Crystal structure of anti-mPEG h15-2b Fab | Descriptor: | 15-2b heavy chain, 15-2b light chain, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL | Authors: | Chang, C.Y, Nguyen, T.M.T, Lin, E.C, Su, Y.C. | Deposit date: | 2022-06-05 | Release date: | 2022-08-10 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Structural determination of an antibody that specifically recognizes polyethylene glycol with a terminal methoxy group. Commun Chem, 5, 2022
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2WWP
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![BU of 2wwp by Molmil](/molmil-images/mine/2wwp) | Crystal structure of the human lipocalin-type prostaglandin D synthase | Descriptor: | CHLORIDE ION, PROSTAGLANDIN-H2 D-ISOMERASE, THIOCYANATE ION | Authors: | Roos, A.K, Tresaugues, L, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Karlberg, T, Kotyenova, T, Kotzch, A, Kraulis, P, Markova, N, Moche, M, Nielsen, T.K, Nyman, T, Persson, C, Schuler, H, Schutz, P, Siponen, M.I, Svensson, L, Thorsell, A.G, Van Den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Wisniewska, M, Nordlund, P, Structural Genomics Consortium (SGC) | Deposit date: | 2009-10-26 | Release date: | 2010-01-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and Dynamic Insights Into Substrate Binding and Catalysis of Human Lipocalin Prostaglandin D Synthase. J.Lipid Res., 54, 2013
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8JCE
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![BU of 8jce by Molmil](/molmil-images/mine/8jce) | Cryo-EM Structure of Chikungunya Virus Nonstructural Protein 1 with m7GpppAmU | Descriptor: | MAGNESIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ... | Authors: | Zhang, K, Law, M.C.Y, Nguyen, T.M, Tan, Y.B, Wirawan, M, Law, Y.S, Luo, D.H. | Deposit date: | 2023-05-11 | Release date: | 2023-11-15 | Last modified: | 2023-12-06 | Method: | ELECTRON MICROSCOPY (2.41 Å) | Cite: | Chikungunya virus nonstructural protein 1 is a versatile RNA capping and decapping enzyme. J.Biol.Chem., 299, 2023
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7YIZ
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![BU of 7yiz by Molmil](/molmil-images/mine/7yiz) | Crystal structure of anti-mPEG h15-2b Fab W104Y mutant | Descriptor: | 15-2b W104Y heavy chain, 15-2b light chain, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL | Authors: | Chang, C.Y, Nguyen, T.M.T, Li, Y.C, Su, Y.C. | Deposit date: | 2022-07-18 | Release date: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Crystal structure of anti-mPEG h15-2b Fab W104Y mutant To Be Published
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8PK0
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![BU of 8pk0 by Molmil](/molmil-images/mine/8pk0) | human mitoribosomal large subunit assembly intermediate 1 with GTPBP10-GTPBP7 | Descriptor: | 16S rRNA + pre-H68-71 segment, 39S ribosomal protein L10, mitochondrial, ... | Authors: | Kummer, E, Nguyen, T.G, Ritter, C. | Deposit date: | 2023-06-23 | Release date: | 2023-12-13 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.03 Å) | Cite: | Structural insights into the role of GTPBP10 in the RNA maturation of the mitoribosome. Nat Commun, 14, 2023
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8QSJ
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![BU of 8qsj by Molmil](/molmil-images/mine/8qsj) | Human mitoribosomal large subunit assembly intermediate 2 with GTPBP7 | Descriptor: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | Authors: | Ritter, C, Nguyen, T.G, Kummer, E. | Deposit date: | 2023-10-10 | Release date: | 2023-12-13 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural insights into the role of GTPBP10 in the RNA maturation of the mitoribosome. Nat Commun, 14, 2023
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7COK
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![BU of 7cok by Molmil](/molmil-images/mine/7cok) | Crystal structure of ligand-free form of 5-ketofructose reductase of Gluconobacter sp. strain CHM43 | Descriptor: | 5-ketofructose reductase | Authors: | Noda, S, Hodoya, Y, Nguyen, T.M, Kataoka, N, Adachi, O, Matsutani, M, Matsushita, K, Yakushi, T, Goto, M. | Deposit date: | 2020-08-04 | Release date: | 2021-08-04 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The 5-Ketofructose Reductase of Gluconobacter sp. Strain CHM43 Is a Novel Class in the Shikimate Dehydrogenase Family. J.Bacteriol., 203, 2021
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7COL
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![BU of 7col by Molmil](/molmil-images/mine/7col) | Crystal structure of 5-ketofructose reductase complexed with NADPH | Descriptor: | 5-ketofructose reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Hodoya, Y, Noda, S, Nguyen, T.M, Kataoka, N, Adachi, O, Matsutani, M, Matsushita, K, Yakushi, T, Goto, M. | Deposit date: | 2020-08-04 | Release date: | 2021-08-04 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The 5-Ketofructose Reductase of Gluconobacter sp. Strain CHM43 Is a Novel Class in the Shikimate Dehydrogenase Family. J.Bacteriol., 203, 2021
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6LD8
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![BU of 6ld8 by Molmil](/molmil-images/mine/6ld8) | |
6LGO
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![BU of 6lgo by Molmil](/molmil-images/mine/6lgo) | |
6LD7
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![BU of 6ld7 by Molmil](/molmil-images/mine/6ld7) | |
6LD9
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![BU of 6ld9 by Molmil](/molmil-images/mine/6ld9) | |
3H95
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![BU of 3h95 by Molmil](/molmil-images/mine/3h95) | Crystal structure of the NUDIX domain of NUDT6 | Descriptor: | CITRATE ANION, GLYCEROL, Nucleoside diphosphate-linked moiety X motif 6 | Authors: | Tresaugues, L, Moche, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Karlberg, T, Kotyenova, T, Kotzch, A, Nielsen, T.K, Nyman, T, Persson, C, Sagemark, J, Schueler, H, Schutz, P, Siponen, M.I, Svensson, L, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Welin, M, Wisniewska, M, Nordlund, P, Structural Genomics Consortium (SGC) | Deposit date: | 2009-04-30 | Release date: | 2009-07-07 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of the NUDIX domain of NUDT6 To be Published
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7X01
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![BU of 7x01 by Molmil](/molmil-images/mine/7x01) | Cryo-EM Structure of Chikungunya Virus Nonstructural Protein 1 with inhibitor FHA | Descriptor: | (1R,2S,3S,4R,5R)-3-(6-aminopurin-9-yl)-4-fluoranyl-5-(2-hydroxyethyl)cyclopentane-1,2-diol, ZINC ION, mRNA-capping enzyme nsP1 | Authors: | Zhang, K, Law, M.C.Y, Nguyen, T.M, Tan, Y.B, Wirawan, M, Law, Y.S, Luo, D.H. | Deposit date: | 2022-02-20 | Release date: | 2022-08-10 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.62 Å) | Cite: | Molecular basis of specific viral RNA recognition and 5'-end capping by the Chikungunya virus nsP1. Cell Rep, 40, 2022
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2WWE
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![BU of 2wwe by Molmil](/molmil-images/mine/2wwe) | Crystal structure of the phox homology domain of human phosphoinositide-3-kinase-C2-gamma | Descriptor: | PHOSPHOINOSITIDE-3-KINASE, CLASS 2, GAMMA POLYPEPTIDE | Authors: | Roos, A.K, Tresaugues, L, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Karlberg, T, Kotyenova, T, Kotzch, A, Kraulis, P, Markova, N, Moche, M, Nielsen, T.K, Nyman, T, Persson, C, Schuler, H, Schutz, P, Siponen, M.I, Svensson, L, Thorsell, A.G, Van Der Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Wisniewska, M, Nordlund, P, Structural Genomics Consortium (SGC) | Deposit date: | 2009-10-22 | Release date: | 2009-11-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Crystal Structure of the Phox Homology Domain of Human Phosphoinositide-3-Kinase-C2-Gamma To be Published
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3HK9
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![BU of 3hk9 by Molmil](/molmil-images/mine/3hk9) | Crystal structure of uronate isomerase from Bacillus halodurans complexed with zinc and D-Glucuronate | Descriptor: | CARBONATE ION, CHLORIDE ION, D-glucuronic acid, ... | Authors: | Fedorov, A.A, Fedorov, E.V, Nguyen, T.T, Raushel, F.M, Almo, S.C. | Deposit date: | 2009-05-22 | Release date: | 2009-08-25 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The mechanism of the reaction catalyzed by uronate isomerase illustrates how an isomerase may have evolved from a hydrolase within the amidohydrolase superfamily. Biochemistry, 48, 2009
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3HK7
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![BU of 3hk7 by Molmil](/molmil-images/mine/3hk7) | Crystal structure of uronate isomerase from Bacillus halodurans complexed with zinc and D-Arabinarate, monoclinic crystal form | Descriptor: | CARBONATE ION, CHLORIDE ION, D-arabinaric acid, ... | Authors: | Fedorov, A.A, Fedorov, E.V, Nguyen, T.T, Raushel, F.M, Almo, S.C. | Deposit date: | 2009-05-22 | Release date: | 2009-08-25 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The mechanism of the reaction catalyzed by uronate isomerase illustrates how an isomerase may have evolved from a hydrolase within the amidohydrolase superfamily. Biochemistry, 48, 2009
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3IUC
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![BU of 3iuc by Molmil](/molmil-images/mine/3iuc) | Crystal structure of the human 70kDa heat shock protein 5 (BiP/GRP78) ATPase domain in complex with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Heat shock 70kDa protein 5 (Glucose-regulated protein, ... | Authors: | Wisniewska, M, Karlberg, T, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Kotyenova, T, Kotzch, A, Kraulis, P, Markova, N, Moche, M, Nielsen, T.K, Nordlund, P, Nyman, T, Persson, C, Roos, A, Schutz, P, Siponen, M.I, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Schuler, H, Structural Genomics Consortium (SGC) | Deposit date: | 2009-08-31 | Release date: | 2009-09-22 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures of the ATPase domains of four human Hsp70 isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78 Plos One, 5, 2010
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7QXS
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![BU of 7qxs by Molmil](/molmil-images/mine/7qxs) | Cryo-EM structure of human telomerase-DNA-TPP1-POT1 complex (with POT1 side chains) | Descriptor: | Adrenocortical dysplasia homolog (Mouse), isoform CRA_a, Histone H2A, ... | Authors: | Sekne, Z, Ghanim, G.E, van Roon, A.M.M, Nguyen, T.H.D. | Deposit date: | 2022-01-27 | Release date: | 2022-03-02 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (3.91 Å) | Cite: | Structural basis of human telomerase recruitment by TPP1-POT1. Science, 375, 2022
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7QXA
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![BU of 7qxa by Molmil](/molmil-images/mine/7qxa) | Cryo-EM map of human telomerase-DNA-TPP1 complex (sharpened) | Descriptor: | Adrenocortical dysplasia homolog (Mouse), isoform CRA_a, Histone H2A, ... | Authors: | Sekne, Z, Ghanim, G.E, van Roon, A.M.M, Nguyen, T.H.D. | Deposit date: | 2022-01-26 | Release date: | 2022-03-02 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis of human telomerase recruitment by TPP1-POT1. Science, 375, 2022
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7QXB
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![BU of 7qxb by Molmil](/molmil-images/mine/7qxb) | Cryo-EM map of human telomerase-DNA-TPP1-POT1 complex (sharpened map) | Descriptor: | Adrenocortical dysplasia homolog (Mouse), isoform CRA_a, Histone H2A, ... | Authors: | Sekne, Z, Ghanim, G.E, van Roon, A.M.M, Nguyen, T.H.D. | Deposit date: | 2022-01-26 | Release date: | 2022-03-02 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (3.91 Å) | Cite: | Structural basis of human telomerase recruitment by TPP1-POT1. Science, 375, 2022
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4PTW
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![BU of 4ptw by Molmil](/molmil-images/mine/4ptw) | Halothermothrix orenii beta-glucosidase A, 2-deoxy-2-fluoro-glucose complex | Descriptor: | 2-deoxy-2-fluoro-alpha-D-glucopyranose, Glycoside hydrolase family 1, TETRAETHYLENE GLYCOL | Authors: | Hassan, N, Nguyen, T.H, Kori, L.D, Patel, B.K.C, Haltrich, D, Divne, C, Tan, T.C. | Deposit date: | 2014-03-11 | Release date: | 2014-09-24 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Biochemical and structural characterization of a thermostable beta-glucosidase from Halothermothrix orenii for galacto-oligosaccharide synthesis. Appl.Microbiol.Biotechnol., 99, 2015
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1C4R
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![BU of 1c4r by Molmil](/molmil-images/mine/1c4r) | THE STRUCTURE OF THE LIGAND-BINDING DOMAIN OF NEUREXIN 1BETA: REGULATION OF LNS DOMAIN FUNCTION BY ALTERNATIVE SPLICING | Descriptor: | NEUREXIN-I BETA | Authors: | Rudenko, G, Nguyen, T, Chelliah, Y, Sudhof, T.C, Deisenhofer, J. | Deposit date: | 1999-09-28 | Release date: | 2000-10-04 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The structure of the ligand-binding domain of neurexin Ibeta: regulation of LNS domain function by alternative splicing. Cell(Cambridge,Mass.), 99, 1999
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