3SB7
| Cu-mediated Trimer of T4 Lysozyme D61H/K65H/R76H/R80H by Synthetic Symmetrization | Descriptor: | COPPER (II) ION, GLYCEROL, Lysozyme | Authors: | Soriaga, A.B, Laganowsky, A, Zhao, M, Sawaya, M.R, Cascio, D, Yeates, T.O. | Deposit date: | 2011-06-03 | Release date: | 2011-09-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Sci., 20, 2011
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4LIW
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8V9O
| Imaging scaffold engineered to bind the therapeutic protein target BARD1 | Descriptor: | CALCIUM ION, Tetrahedral Nanocage Cage Component Fused to Anti-BARD1 Darpin, Tetrahedral Nanocage Cage, ... | Authors: | Agdanowski, M.P, Castells-Graells, R, Sawaya, M.R, Yeates, T.O, Arbing, M.A. | Deposit date: | 2023-12-08 | Release date: | 2024-05-15 | Last modified: | 2024-06-12 | Method: | X-RAY DIFFRACTION (3.81 Å) | Cite: | X-ray crystal structure of a designed rigidified imaging scaffold in the ligand-free conformation. Acta Crystallogr.,Sect.F, 80, 2024
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1YAC
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2Z9H
| Ethanolamine utilization protein, EutN | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, CHLORIDE ION, Ethanolamine utilization protein eutN | Authors: | Tanaka, S, Sawaya, M.R, Yeates, T.O. | Deposit date: | 2007-09-20 | Release date: | 2007-10-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | The crystal structure of ethanolamine utilization protein EutN from E. coli To be Published
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3BN4
| Carboxysome Subunit, CcmK1 | Descriptor: | Carbon dioxide-concentrating mechanism protein ccmK homolog 1, SULFATE ION | Authors: | Tanaka, S, Sawaya, M.R, Yeates, T.O. | Deposit date: | 2007-12-13 | Release date: | 2008-03-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Atomic-level models of the bacterial carboxysome shell. Science, 319, 2008
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5UI2
| CRYSTAL STRUCTURE OF ORANGE CAROTENOID PROTEIN | Descriptor: | (3'R)-3'-hydroxy-beta,beta-caroten-4-one, CHLORIDE ION, Orange carotenoid-binding protein, ... | Authors: | KERFELD, C.A, SAWAYA, M.R, VISHNU, B, KROGMANN, D, YEATES, T.O. | Deposit date: | 2017-01-12 | Release date: | 2017-01-25 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The crystal structure of a cyanobacterial water-soluble carotenoid binding protein. Structure, 11, 2003
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2B5O
| ferredoxin-NADP reductase | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Ferredoxin--NADP reductase, SULFATE ION | Authors: | Sawaya, M.R, Kerfeld, C.A, Gomez-Lojero, C, Krogmann, D, Bryant, D.A, Yeates, T.O. | Deposit date: | 2005-09-29 | Release date: | 2005-10-11 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.499 Å) | Cite: | Crystal Structure of Ferredoxin-NADP reductase from Synechococcus sp. (PCC 7002) To be Published
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2EWH
| Carboxysome protein CsoS1A from Halothiobacillus neapolitanus | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Major carboxysome shell protein 1A | Authors: | Tsai, Y, Sawaya, M.R, Kerfeld, C.A, Yeates, T.O. | Deposit date: | 2005-11-03 | Release date: | 2006-11-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural Analysis of CsoS1A and the Protein Shell of the Halothiobacillus neapolitanus Carboxysome. Plos Biol., 5, 2007
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8G47
| KRAS G12C complex with GDP and AMG 510 imaged on a cryo-EM imaging scaffold | Descriptor: | AMG 510 (bound form), GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Castells-Graells, R, Sawaya, M.R, Yeates, T.O. | Deposit date: | 2023-02-08 | Release date: | 2023-08-09 | Last modified: | 2023-09-27 | Method: | ELECTRON MICROSCOPY (3.19 Å) | Cite: | Cryo-EM structure determination of small therapeutic protein targets at 3 angstrom -resolution using a rigid imaging scaffold. Proc.Natl.Acad.Sci.USA, 120, 2023
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8G3K
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6ARD
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6ARC
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8G4E
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8G4H
| KRAS G13C complex with GDP imaged on a cryo-EM imaging scaffold | Descriptor: | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Castells-Graells, R, Sawaya, M.R, Yeates, T.O. | Deposit date: | 2023-02-09 | Release date: | 2023-08-09 | Last modified: | 2023-09-27 | Method: | ELECTRON MICROSCOPY (2.87 Å) | Cite: | Cryo-EM structure determination of small therapeutic protein targets at 3 angstrom -resolution using a rigid imaging scaffold. Proc.Natl.Acad.Sci.USA, 120, 2023
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8G42
| KRAS G12C complex with GDP imaged on a cryo-EM imaging scaffold | Descriptor: | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Castells-Graells, R, Sawaya, M.R, Yeates, T.O. | Deposit date: | 2023-02-08 | Release date: | 2023-08-09 | Last modified: | 2023-09-27 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | Cryo-EM structure determination of small therapeutic protein targets at 3 angstrom -resolution using a rigid imaging scaffold. Proc.Natl.Acad.Sci.USA, 120, 2023
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8G4F
| KRAS G12V complex with GDP imaged on a cryo-EM imaging scaffold | Descriptor: | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Castells-Graells, R, Sawaya, M.R, Yeates, T.O. | Deposit date: | 2023-02-09 | Release date: | 2023-08-09 | Last modified: | 2023-09-27 | Method: | ELECTRON MICROSCOPY (2.91 Å) | Cite: | Cryo-EM structure determination of small therapeutic protein targets at 3 angstrom -resolution using a rigid imaging scaffold. Proc.Natl.Acad.Sci.USA, 120, 2023
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6NHT
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6NHV
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6C9I
| Single-Particle reconstruction of DARP14 - A designed protein scaffold displaying ~17kDa DARPin proteins - Scaffold | Descriptor: | DARP14 - Subunit A with DARPin, DARP14 - Subunit B | Authors: | Gonen, S, Liu, Y, Yeates, T.O, Gonen, T. | Deposit date: | 2018-01-26 | Release date: | 2018-03-21 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.09 Å) | Cite: | Near-atomic cryo-EM imaging of a small protein displayed on a designed scaffolding system. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6C9K
| Single-Particle reconstruction of DARP14 - A designed protein scaffold displaying ~17kDa DARPin proteins | Descriptor: | DARP14 - Subunit A with DARPin, DARP14 - Subunit B | Authors: | Gonen, S, Liu, Y, Yeates, T.O, Gonen, T. | Deposit date: | 2018-01-26 | Release date: | 2018-03-21 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.49 Å) | Cite: | Near-atomic cryo-EM imaging of a small protein displayed on a designed scaffolding system. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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2A1B
| Carboxysome shell protein ccmK2 | Descriptor: | Carbon dioxide concentrating mechanism protein ccmK homolog 2 | Authors: | Kerfeld, C.A, Sawaya, M.R, Tanaka, S, Nguyen, C.V, Phillips, M, Beeby, M, Yeates, T.O. | Deposit date: | 2005-06-20 | Release date: | 2005-08-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Protein structures forming the shell of primitive bacterial organelles Science, 309, 2005
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2A10
| carboxysome shell protein ccmK4 | Descriptor: | Carbon dioxide concentrating mechanism protein ccmK homolog 4 | Authors: | Kerfeld, C.A, Sawaya, M.R, Tanaka, S, Nguyen, C.V, Phillips, M, Beeby, M, Yeates, T.O. | Deposit date: | 2005-06-17 | Release date: | 2005-08-09 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.803 Å) | Cite: | Protein structures forming the shell of primitive bacterial organelles Science, 309, 2005
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2A5X
| Crystal Structure of a Cross-linked Actin Dimer | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Actin, alpha skeletal muscle, ... | Authors: | Kudryashov, D.S, Sawaya, M.R, Adisetiyo, H, Norcross, T, Hegyi, G, Reisler, E, Yeates, T.O. | Deposit date: | 2005-07-01 | Release date: | 2005-08-23 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | The crystal structure of a cross-linked actin dimer suggests a detailed molecular interface in F-actin Proc.Natl.Acad.Sci.Usa, 102, 2005
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2A18
| carboxysome shell protein ccmK4, crystal form 2 | Descriptor: | AMMONIUM ION, Carbon dioxide concentrating mechanism protein ccmK homolog 4 | Authors: | Kerfeld, C.A, Sawaya, M.R, Tanaka, S, Nguyen, C.V, Phillips, M, Beeby, M, Yeates, T.O. | Deposit date: | 2005-06-18 | Release date: | 2005-08-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Protein structures forming the shell of primitive bacterial organelles Science, 309, 2005
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