3B1O
| Structure of Burkholderia thailandensis nucleoside kinase (BthNK) in ligand-free form | Descriptor: | Ribokinase, putative | Authors: | Yasutake, Y, Ota, H, Hino, E, Sakasegawa, S, Tamura, T. | Deposit date: | 2011-07-05 | Release date: | 2011-11-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structures of Burkholderia thailandensis nucleoside kinase: implications for the catalytic mechanism and nucleoside selectivity Acta Crystallogr.,Sect.D, 67, 2011
|
|
5C9I
| |
7YM0
| Lysoplasmalogen-specific phospholipase D (LyPls-PLD) with Ca2+ | Descriptor: | CALCIUM ION, Lysoplasmalogenase | Authors: | Yasutake, Y, Sakasegawa, S, Sugimori, D, Murayama, K. | Deposit date: | 2022-07-27 | Release date: | 2023-01-04 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | Structural basis for the substrate specificity switching of lysoplasmalogen-specific phospholipase D from Thermocrispum sp. RD004668. Biosci.Biotechnol.Biochem., 87, 2022
|
|
8X22
| HIV-1 reverse transcriptase mutant Q151M/Y115F/F116Y/L74V:DNA:dGTP ternary complex | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA/RNA (38-MER), GLYCEROL, ... | Authors: | Yasutake, Y, Hattori, S.I, Mitsuya, H. | Deposit date: | 2023-11-09 | Release date: | 2024-07-17 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Deviated binding of anti-HBV nucleoside analog E-CFCP-TP to the reverse transcriptase active site attenuates the effect of drug-resistant mutations. Sci Rep, 14, 2024
|
|
8X21
| HIV-1 reverse transcriptase mutant Q151M/Y115F/F116Y/L74V:DNA:ETV-TP ternary complex | Descriptor: | DNA/RNA (38-MER), GLYCEROL, HIV-1 RT p51 subunit, ... | Authors: | Yasutake, Y, Hattori, S.I, Mitsuya, H. | Deposit date: | 2023-11-09 | Release date: | 2024-07-17 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Deviated binding of anti-HBV nucleoside analog E-CFCP-TP to the reverse transcriptase active site attenuates the effect of drug-resistant mutations. Sci Rep, 14, 2024
|
|
8X1Z
| HIV-1 reverse transcriptase mutant Q151M/Y115F/F116Y:DNA:E-CFCP-TP ternary complex | Descriptor: | DNA/RNA (38-MER), E-CFCP-triphosphate, GLYCEROL, ... | Authors: | Yasutake, Y, Hattori, S.I, Mitsuya, H. | Deposit date: | 2023-11-09 | Release date: | 2024-07-17 | Method: | X-RAY DIFFRACTION (2.62 Å) | Cite: | Deviated binding of anti-HBV nucleoside analog E-CFCP-TP to the reverse transcriptase active site attenuates the effect of drug-resistant mutations. Sci Rep, 14, 2024
|
|
8X20
| HIV-1 reverse transcriptase mutant Q151M/Y115F/F116Y/L74V:DNA:E-CFCP-TP ternary complex | Descriptor: | DNA/RNA (38-MER), E-CFCP-triphosphate, GLYCEROL, ... | Authors: | Yasutake, Y, Hattori, S.I, Mitsuya, H. | Deposit date: | 2023-11-09 | Release date: | 2024-07-17 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Deviated binding of anti-HBV nucleoside analog E-CFCP-TP to the reverse transcriptase active site attenuates the effect of drug-resistant mutations. Sci Rep, 14, 2024
|
|
5GNM
| Cytochrome P450 Vdh (CYP107BR1) L348M mutant | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, Vitamin D(3) 25-hydroxylase | Authors: | Yasutake, Y, Tamura, T. | Deposit date: | 2016-07-22 | Release date: | 2017-05-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural insights into the mechanism of the drastic changes in enzymatic activity of the cytochrome P450 vitamin D3 hydroxylase (CYP107BR1) caused by a mutation distant from the active site Acta Crystallogr F Struct Biol Commun, 73, 2017
|
|
5GNL
| Cytochrome P450 Vdh (CYP107BR1) F106V mutant | Descriptor: | 2-(2-METHOXYETHOXY)ETHANOL, PROTOPORPHYRIN IX CONTAINING FE, Vitamin D(3) 25-hydroxylase | Authors: | Yasutake, Y, Tamura, T. | Deposit date: | 2016-07-22 | Release date: | 2017-05-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural insights into the mechanism of the drastic changes in enzymatic activity of the cytochrome P450 vitamin D3 hydroxylase (CYP107BR1) caused by a mutation distant from the active site Acta Crystallogr F Struct Biol Commun, 73, 2017
|
|
1J1W
| Crystal Structure Of The Monomeric Isocitrate Dehydrogenase In Complex With NADP+ | Descriptor: | Isocitrate Dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Yasutake, Y, Watanabe, S, Yao, M, Takada, Y, Fukunaga, N, Tanaka, I. | Deposit date: | 2002-12-19 | Release date: | 2003-09-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal Structure of the Monomeric Isocitrate Dehydrogenase in the Presence of NADP+ J.Biol.Chem., 278, 2003
|
|
1ITW
| Crystal structure of the monomeric isocitrate dehydrogenase in complex with isocitrate and Mn | Descriptor: | ISOCITRIC ACID, Isocitrate dehydrogenase, MANGANESE (II) ION | Authors: | Yasutake, Y, Watanabe, S, Yao, M, Takada, Y, Fukunaga, N, Tanaka, I. | Deposit date: | 2002-02-12 | Release date: | 2002-12-11 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure of the Monomeric Isocitrate Dehydrogenase: Evidence of a Protein Monomerization by a Domain Duplication Structure, 10, 2002
|
|
7DBN
| HIV-1 reverse transcriptase mutant Q151M/Y115F/F116Y/M184V/F160M:DNA:dCTP ternary complex | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA/RNA (38-MER), GLYCEROL, ... | Authors: | Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K. | Deposit date: | 2020-10-21 | Release date: | 2021-08-04 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.67 Å) | Cite: | Biochemical and Structural Properties of Entecavir-Resistant Hepatitis B Virus Polymerase with L180M/M204V Mutations. J.Virol., 95, 2021
|
|
7DBM
| HIV-1 reverse transcriptase mutant Q151M/Y115F/F116Y/M184V:DNA:dGTP ternary complex | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA/RNA (38-MER), GLYCEROL, ... | Authors: | Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K. | Deposit date: | 2020-10-21 | Release date: | 2021-08-04 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Biochemical and Structural Properties of Entecavir-Resistant Hepatitis B Virus Polymerase with L180M/M204V Mutations. J.Virol., 95, 2021
|
|
5XN1
| HIV-1 reverse transcriptase Q151M:DNA:entecavir-triphosphate ternary complex | Descriptor: | 38-MER DNA aptamer, GLYCEROL, MAGNESIUM ION, ... | Authors: | Yasutake, Y, Tamura, N, Hayashi, H, Maeda, K. | Deposit date: | 2017-05-17 | Release date: | 2018-02-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.446 Å) | Cite: | HIV-1 with HBV-associated Q151M substitution in RT becomes highly susceptible to entecavir: structural insights into HBV-RT inhibition by entecavir. Sci Rep, 8, 2018
|
|
5XN0
| HIV-1 reverse transcriptase Q151M:DNA binary complex | Descriptor: | 38-MER DNA aptamer, GLYCEROL, Pol protein, ... | Authors: | Yasutake, Y, Tamura, N, Hayashi, H, Maeda, K. | Deposit date: | 2017-05-17 | Release date: | 2018-02-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.596 Å) | Cite: | HIV-1 with HBV-associated Q151M substitution in RT becomes highly susceptible to entecavir: structural insights into HBV-RT inhibition by entecavir. Sci Rep, 8, 2018
|
|
5XN2
| HIV-1 reverse transcriptase Q151M:DNA:dGTP ternary complex | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 38-MER DNA aptamer, GLYCEROL, ... | Authors: | Yasutake, Y, Tamura, N, Hayashi, H, Maeda, K. | Deposit date: | 2017-05-17 | Release date: | 2018-02-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.381 Å) | Cite: | HIV-1 with HBV-associated Q151M substitution in RT becomes highly susceptible to entecavir: structural insights into HBV-RT inhibition by entecavir. Sci Rep, 8, 2018
|
|
7COF
| |
7COG
| |
4PB3
| D-threo-3-hydroxyaspartate dehydratase H351A mutant | Descriptor: | D-threo-3-hydroxyaspartate dehydratase, MAGNESIUM ION, PYRIDOXAL-5'-PHOSPHATE | Authors: | Yasutake, Y, Matsumoto, Y, Wada, M. | Deposit date: | 2014-04-11 | Release date: | 2015-03-11 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural insights into the substrate stereospecificity of D-threo-3-hydroxyaspartate dehydratase from Delftia sp. HT23: a useful enzyme for the synthesis of optically pure L-threo- and D-erythro-3-hydroxyaspartate. Appl.Microbiol.Biotechnol., 99, 2015
|
|
4PB5
| D-threo-3-hydroxyaspartate dehydratase H351A mutant complexed with L-erythro-3-hydroxyaspartate | Descriptor: | (3R)-3-hydroxy-L-aspartic acid, D-threo-3-hydroxyaspartate dehydratase, GLYCEROL, ... | Authors: | Yasutake, Y, Matsumoto, Y, Wada, M. | Deposit date: | 2014-04-11 | Release date: | 2015-03-11 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural insights into the substrate stereospecificity of D-threo-3-hydroxyaspartate dehydratase from Delftia sp. HT23: a useful enzyme for the synthesis of optically pure L-threo- and D-erythro-3-hydroxyaspartate. Appl.Microbiol.Biotechnol., 99, 2015
|
|
2DTX
| Structure of Thermoplasma acidophilum aldohexose dehydrogenase (AldT) in complex with D-mannose | Descriptor: | Glucose 1-dehydrogenase related protein, SULFATE ION, beta-D-mannopyranose | Authors: | Yasutake, Y, Nishiya, Y, Tamura, N, Tamura, T. | Deposit date: | 2006-07-18 | Release date: | 2007-03-27 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural Insights into Unique Substrate Selectivity of Thermoplasma acidophilumd-Aldohexose Dehydrogenase J.Mol.Biol., 367, 2007
|
|
4YF9
| |
4PB4
| D-threo-3-hydroxyaspartate dehydratase H351A mutant complexed with 2-amino maleic acid | Descriptor: | 2-amino maleic acid, D-threo-3-hydroxyaspartate dehydratase, MAGNESIUM ION, ... | Authors: | Yasutake, Y, Matsumoto, Y, Wada, M. | Deposit date: | 2014-04-11 | Release date: | 2015-03-11 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural insights into the substrate stereospecificity of D-threo-3-hydroxyaspartate dehydratase from Delftia sp. HT23: a useful enzyme for the synthesis of optically pure L-threo- and D-erythro-3-hydroxyaspartate. Appl.Microbiol.Biotechnol., 99, 2015
|
|
2DTD
| Structure of Thermoplasma acidophilum aldohexose dehydrogenase (AldT) in ligand-free form | Descriptor: | Glucose 1-dehydrogenase related protein, SULFATE ION | Authors: | Yasutake, Y, Nishiya, Y, Tamura, N, Tamura, T. | Deposit date: | 2006-07-12 | Release date: | 2007-03-27 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Insights into Unique Substrate Selectivity of Thermoplasma acidophilumd-Aldohexose Dehydrogenase J.Mol.Biol., 367, 2007
|
|
2DTE
| Structure of Thermoplasma acidophilum aldohexose dehydrogenase (AldT) in complex with NADH | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Glucose 1-dehydrogenase related protein | Authors: | Yasutake, Y, Nishiya, Y, Tamura, N, Tamura, T. | Deposit date: | 2006-07-12 | Release date: | 2007-03-27 | Last modified: | 2024-10-23 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural Insights into Unique Substrate Selectivity of Thermoplasma acidophilumd-Aldohexose Dehydrogenase J.Mol.Biol., 367, 2007
|
|