5XN0

HIV-1 reverse transcriptase Q151M:DNA binary complex

Summary for 5XN0

• Entry DOI: 10.2210/pdb5xn0/pdb
• Related: 4ZHR
• Related PRD ID: PRD_900003
• Descriptor: Pol protein, 38-MER DNA aptamer, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: hiv-1, hbv, reverse transcriptase, drug resistance, drug sensitivity, transferase-dna complex, transferase/dna
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 6
• Total formula weight: 256041.64

Authors

Yasutake, Y.,Tamura, N.,Hayashi, H.,Maeda, K. (deposition date: 2017-05-17, release date: 2018-02-07, Last modification date: 2023-11-22)

• Primary citation: Yasutake, Y.,Hattori, S.I.,Hayashi, H.,Matsuda, K.,Tamura, N.,Kohgo, S.,Maeda, K.,Mitsuya, H.; HIV-1 with HBV-associated Q151M substitution in RT becomes highly susceptible to entecavir: structural insights into HBV-RT inhibition by entecavir.; Sci Rep, 8:1624-1624, 2018; PubMed: 29374261; DOI: 10.1038/s41598-018-19602-9

Experimental method

X-RAY DIFFRACTION (2.596 Å)