5XN0

HIV-1 reverse transcriptase Q151M:DNA binary complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, C)	Pol protein	polymer	557	64033.4	2	UniProt (D3XFN7) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) Pfam (PF00075) UniProt (by SIFTS) (P12497)	Human immunodeficiency virus 1
2	B, E (B, D)	Pol protein	polymer	444	51861.5	2	UniProt (D3XFN7) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) UniProt (by SIFTS) (P12497)	Human immunodeficiency virus 1
3	C, F (E, F)	38-MER DNA aptamer	polymer	38	11724.5	2		synthetic construct
4	G (G)	beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose	branched		342.3	1	In PDB BIRD (PRD_900003)		sucrose
5	H, I, J, K, L (A, B, E, C, D)	GLYCEROL	non-polymer		92.1	5	Chemie (GOL)
6	M, N, O, P, Q... (A, B, E, C, D...)	water	water		18.0	96	Chemie (HOH)

Sequence modifications

A, C: 1 - 555 (UniProt: D3XFN7)

PDB	External Database	Details
Met -1	-	expression tag
Val 0	-	expression tag
Met 151	Gln 250	engineered mutation
Ser 162	Cys 261	engineered mutation
Ser 280	Cys 379	engineered mutation

B, D: 1 - 428 (UniProt: D3XFN7)

PDB	External Database	Details
Met -15	-	expression tag
Ala -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
Ala -7	-	expression tag
Leu -6	-	expression tag
Glu -5	-	expression tag
Val -4	-	expression tag
Leu -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Gly 0	-	expression tag
Ser 162	Cys 261	engineered mutation
Ser 280	Cys 379	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	255238.9
Branched	Number of molecules	1
	Total formula weight	342.3
Non-Polymers*	Number of molecules	5
	Total formula weight	460.5
All*	Total formula weight	256041.6

*Water molecules are not included.