5KLK
 
 | | Crystal structure of 2-aminomuconate 6-semialdehyde dehydrogenase N169D in complex with NAD+ and 2-hydroxymuconate-6-semialdehyde | | Descriptor: | (2E,4E)-2-hydroxy-6-oxohexa-2,4-dienoic acid, 2-aminomuconate 6-semialdehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | Authors: | Yang, Y, Davis, I, Ha, U, Wang, Y, Shin, I, Liu, A. | | Deposit date: | 2016-06-24 | | Release date: | 2016-11-09 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.006 Å) | | Cite: | A Pitcher-and-Catcher Mechanism Drives Endogenous Substrate Isomerization by a Dehydrogenase in Kynurenine Metabolism.
J.Biol.Chem., 291, 2016
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5KLN
 | | Crystal structure of 2-aminomuconate 6-semialdehyde dehydrogenase N169A in complex with NAD+ | | Descriptor: | 2-aminomuconate 6-semialdehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SODIUM ION | | Authors: | Yang, Y, Davis, I, Ha, U, Wang, Y, Shin, I, Liu, A. | | Deposit date: | 2016-06-24 | | Release date: | 2016-11-09 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.992 Å) | | Cite: | A Pitcher-and-Catcher Mechanism Drives Endogenous Substrate Isomerization by a Dehydrogenase in Kynurenine Metabolism.
J.Biol.Chem., 291, 2016
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6U6F
 | | The crystal structure of anti-apoptotic Mcl-1 protein in complex with 2, 5-substituted benzoic acid inhibitor 21 | | Descriptor: | 2-[({4-[(4-tert-butylphenyl)methyl]piperazin-1-yl}sulfonyl)amino]-5-[(2-phenylethyl)sulfanyl]benzoic acid, Induced myeloid leukemia cell differentiation protein Mcl-1 | | Authors: | Yang, Y, Stuckey, J.A, Nikolovska-Coleska, Z. | | Deposit date: | 2019-08-29 | | Release date: | 2020-03-04 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Discovery and Characterization of 2,5-Substituted Benzoic Acid Dual Inhibitors of the Anti-apoptotic Mcl-1 and Bfl-1 Proteins.
J.Med.Chem., 63, 2020
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6U46
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6OC2
 | | CSP1-cyc(Orn6D10) | | Descriptor: | Competence-stimulating peptide type 1 | | Authors: | Yang, Y. | | Deposit date: | 2019-03-21 | | Release date: | 2020-01-08 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Designing cyclic competence-stimulating peptide (CSP) analogs with pan-group quorum-sensing inhibition activity inStreptococcus pneumoniae.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6OBW
 | | CSP1-cyc(K6D10) | | Descriptor: | Competence-stimulating peptide type 1 | | Authors: | Yang, Y. | | Deposit date: | 2019-03-21 | | Release date: | 2020-01-08 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Designing cyclic competence-stimulating peptide (CSP) analogs with pan-group quorum-sensing inhibition activity inStreptococcus pneumoniae.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6OC4
 | | CSP1-cyc(Dab6E10) | | Descriptor: | Competence-stimulating peptide type 1 | | Authors: | Yang, Y. | | Deposit date: | 2019-03-21 | | Release date: | 2020-01-08 | | Last modified: | 2020-02-05 | | Method: | SOLUTION NMR | | Cite: | Designing cyclic competence-stimulating peptide (CSP) analogs with pan-group quorum-sensing inhibition activity inStreptococcus pneumoniae.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6V1N
 | | CSP1-E1A-cyc(Dap6E10) | | Descriptor: | Competence-stimulating peptide type 1 | | Authors: | Yang, Y. | | Deposit date: | 2019-11-20 | | Release date: | 2020-01-08 | | Last modified: | 2020-02-05 | | Method: | SOLUTION NMR | | Cite: | Designing cyclic competence-stimulating peptide (CSP) analogs with pan-group quorum-sensing inhibition activity inStreptococcus pneumoniae.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6WVG
 | | human CD53 | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, Green fluorescent protein, ... | | Authors: | Yang, Y, Liu, S, Li, W. | | Deposit date: | 2020-05-06 | | Release date: | 2020-09-16 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Open conformation of tetraspanins shapes interaction partner networks on cell membranes.
Embo J., 39, 2020
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6LGK
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6LGJ
 | | Crystal structure of an oxido-reductase | | Descriptor: | Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | Authors: | Yang, Y, Lei, J, Yin, L. | | Deposit date: | 2019-12-05 | | Release date: | 2020-12-09 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of an oxido-reductase
To be published
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6LGM
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1N5H
 | | Solution structure of the cathelin-like domain of protegrins (the R87-P88 and D118-P119 amide bonds are in the cis conformation) | | Descriptor: | protegrins | | Authors: | Yang, Y, Sanchez, J.F, Strub, M.P, Brutscher, B, Aumelas, A. | | Deposit date: | 2002-11-06 | | Release date: | 2003-06-03 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | NMR Structure of the Cathelin-like domain of the protegrin-3 Precursor
Biochemistry, 42, 2003
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1N5P
 | | Solution structure of the cathelin-like domain of protegrins (all amide bonds involving proline residues are in trans conformation) | | Descriptor: | protegrins | | Authors: | Yang, Y, Sanchez, J.F, Strub, M.P, Brutscher, B, Aumelas, A. | | Deposit date: | 2002-11-07 | | Release date: | 2003-06-03 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | NMR Structure of the Cathelin-like domain of the protegrin-3 Precursor
Biochemistry, 42, 2003
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1P53
 | | The Crystal Structure of ICAM-1 D3-D5 fragment | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Intercellular adhesion molecule-1 | | Authors: | Yang, Y, Jun, C.D, Liu, J.H, Zhang, R, Jochimiak, A, Springer, T.A, Wang, J.H. | | Deposit date: | 2003-04-24 | | Release date: | 2004-05-04 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3.06 Å) | | Cite: | Structural basis for dimerization of ICAM-1 on the cell surface.
Mol.Cell, 14, 2004
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2JOB
 | | Solution structure of an antilipopolysaccharide factor from shrimp and its possible Lipid A binding site | | Descriptor: | antilipopolysaccharide factor | | Authors: | Yang, Y, Boze, H, Chemardin, P, Padilla, A, Moulin, G, Tassanakajon, A, Pugniere, M, Roquet, F, Gueguen, Y, Bachere, E, Aumelas, A. | | Deposit date: | 2007-03-02 | | Release date: | 2008-03-11 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | NMR structure of rALF-Pm3, an anti-lipopolysaccharide factor from shrimp: Model of the possible lipid A-binding site
Biopolymers, 91, 2009
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1B4Q
 | | Solution structure of human thioltransferase complex with glutathione | | Descriptor: | GLUTATHIONE, PROTEIN (HUMAN THIOLTRANSFERASE) | | Authors: | Yang, Y, Jao, S.C, Nanduri, S, Starke, D.W, Mieyal, J.J, Qin, J. | | Deposit date: | 1998-12-25 | | Release date: | 1999-12-23 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Reactivity of the human thioltransferase (glutaredoxin) C7S, C25S, C78S, C82S mutant and NMR solution structure of its glutathionyl mixed disulfide intermediate reflect catalytic specificity.
Biochemistry, 37, 1998
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1L1C
 | | Structure of the LicT Bacterial Antiterminator Protein in Complex with its RNA Target | | Descriptor: | Transcription antiterminator licT, licT mRNA antiterminator hairpin | | Authors: | Yang, Y, Declerck, N, Manival, X, Aymerich, S, Kochoyan, M. | | Deposit date: | 2002-02-15 | | Release date: | 2002-03-27 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the LicT-RNA antitermination complex: CAT clamping RAT.
EMBO J., 21, 2002
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3I5H
 | | The crystal structure of rigor like squid myosin S1 in the absence of nucleotide | | Descriptor: | CALCIUM ION, Myosin catalytic light chain LC-1, mantle muscle, ... | | Authors: | Yang, Y, Gourinath, S, Kovacs, M, Nyitray, L, Reutzel, R, Himmel, D.M, O'Neall-Hennessey, E, Reshetnikova, L, Szent-Gyorgyi, A.G, Brown, J.H, Cohen, C. | | Deposit date: | 2009-07-05 | | Release date: | 2009-07-28 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor.
Structure, 15, 2007
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3I5F
 | | Crystal structure of squid MG.ADP myosin S1 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Myosin catalytic light chain LC-1, ... | | Authors: | Yang, Y, Gourinath, S, Kovacs, M, Nyitray, L, Reutzel, R, Himmel, D.M, O'Neall-Hennessey, E, Reshetnikova, L, Szent-Gyorgyi, A.G, Brown, J.H, Cohen, C. | | Deposit date: | 2009-07-05 | | Release date: | 2009-08-04 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor.
Structure, 15, 2007
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3I5G
 | | Crystal structure of rigor-like squid myosin S1 | | Descriptor: | CALCIUM ION, MALONATE ION, Myosin catalytic light chain LC-1, ... | | Authors: | Yang, Y, Gourinath, S, Kovacs, M, Nyitray, L, Reutzel, R, Himmel, D.M, O'Neall-Hennessey, E, Reshetnikova, L, Szent-Gyorgyi, A.G, Brown, J.H, Cohen, C. | | Deposit date: | 2009-07-05 | | Release date: | 2009-07-28 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor.
Structure, 15, 2007
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3I5I
 | | The crystal structure of squid myosin S1 in the presence of SO4 2- | | Descriptor: | CALCIUM ION, Myosin catalytic light chain LC-1, mantle muscle, ... | | Authors: | Yang, Y, Gourinath, S, Kovacs, M, Nyitray, L, Reutzel, R, Himmel, D.M, O'Neall-Hennessey, E, Reshetnikova, L, Szent-Gyorgyi, A.G, Brown, J.H, Cohen, C. | | Deposit date: | 2009-07-05 | | Release date: | 2009-07-28 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor.
Structure, 15, 2007
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8QN7
 | | Amyloid-beta 40 type 1 filament from the leptomeninges of individual with Alzheimer's disease and cerebral amyloid angiopathy | | Descriptor: | Amyloid-beta A4 protein | | Authors: | Yang, Y, Murzin, A.S, Peak-Chew, S.Y, Franco, C, Newell, K.L, Ghetti, B, Goedert, M, Scheres, S.H.W. | | Deposit date: | 2023-09-25 | | Release date: | 2023-12-13 | | Last modified: | 2024-01-31 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Cryo-EM structures of A beta 40 filaments from the leptomeninges of individuals with Alzheimer's disease and cerebral amyloid angiopathy.
Acta Neuropathol Commun, 11, 2023
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8QN6
 | | Amyloid-beta 40 type 2 filament from the leptomeninges of individual with Alzheimer's disease and cerebral amyloid angiopathy | | Descriptor: | Amyloid-beta A4 protein | | Authors: | Yang, Y, Murzin, A.S, Peak-Chew, S.Y, Franco, C, Newell, K.L, Ghetti, B, Goedert, M, Scheres, S.H.W. | | Deposit date: | 2023-09-25 | | Release date: | 2023-12-13 | | Last modified: | 2024-01-31 | | Method: | ELECTRON MICROSCOPY (2.4 Å) | | Cite: | Cryo-EM structures of A beta 40 filaments from the leptomeninges of individuals with Alzheimer's disease and cerebral amyloid angiopathy.
Acta Neuropathol Commun, 11, 2023
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8TLX
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