1S0M
 
 | | Crystal structure of a Benzo[a]pyrene Diol Epoxide adduct in a ternary complex with a DNA polymerase | | Descriptor: | 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*T)-3', ... | | Authors: | Ling, H, Sayer, J.M, Boudsocq, F, Plosky, B.S, Woodgate, R, Yang, W. | | Deposit date: | 2003-12-31 | | Release date: | 2004-03-30 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymerase.
Proc.Natl.Acad.Sci.USA, 101, 2004
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1RYR
 | | REPLICATION OF A CIS-SYN THYMINE DIMER AT ATOMIC RESOLUTION | | Descriptor: | 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*C)-3', 5'-D(*TP*TP*TP*GP*AP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3', ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Ling, H, Boudsocq, F, Plosky, B, Woodgate, R, Yang, W. | | Deposit date: | 2003-12-22 | | Release date: | 2004-02-10 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | Replication of a Cis-Syn Thymine Dimer at Atomic Resolution
Nature, 424, 2003
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1S10
 | | Snapshots of replication through an abasic lesion: structural basis for base substitution and frameshift | | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*CP*TP*A)-3', 5'-D(*TP*CP*AP*GP*TP*AP*GP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3', ... | | Authors: | Ling, H, Boudsocq, F, Woodgate, R, Yang, W. | | Deposit date: | 2004-01-05 | | Release date: | 2004-03-30 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Snapshots of Replication through an Abasic Lesion; Structural Basis for Base Substitutions and Frameshifts.
Mol.Cell, 13, 2004
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1S0N
 | | Snapshots of replication through an abasic lesion: structural basis for base substitution and frameshift | | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*GP*GP*CP*AP*CP*TP*GP*AP*TP*CP*AP*CP*G)-3', 5'-D(*TP*AP*CP*GP*AP*CP*GP*TP*GP*AP*TP*CP*AP*GP*TP*GP*CP*C)-3', ... | | Authors: | Ling, H, Boudsocq, F, Woodgate, R, Yang, W. | | Deposit date: | 2003-12-31 | | Release date: | 2004-03-30 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Snapshots of Replication through an Abasic Lesion; Structural Basis for Base Substitutions and Frameshifts.
Mol.Cell, 13, 2004
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1S0O
 | | Snapshots of replication through an abasic lesion: structural basis for base substitution and frameshift | | Descriptor: | 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*CP*TP*C)-3', 5'-D(*TP*CP*AP*GP*TP*AP*GP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3', CALCIUM ION, ... | | Authors: | Ling, H, Boudsocq, F, Woodgate, R, Yang, W. | | Deposit date: | 2003-12-31 | | Release date: | 2004-03-30 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Snapshots of Replication through an Abasic Lesion; Structural Basis for Base Substitutions and Frameshifts.
Mol.Cell, 13, 2004
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4B3O
 | | Structures of HIV-1 RT and RNA-DNA Complex Reveal a Unique RT Conformation and Substrate Interface | | Descriptor: | (-)-6-CHLORO-4-CYCLOPROPYLETHYNYL-4-TRIFLUOROMETHYL-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONE, 5'-D(*CP*GP*TP*AP*TP*GP*CP*CP*TP*AP*TP*AP*GP*TP *TP*AP*TP*TP*GP*TP*GP*GP*CP*C)-3', 5'-R(*AP*UP*GP*AP*3DRP*GP*GP*CP*CP*AP*CP*AP*AP*UP*AP *AP*CP*UP*AP*UP*AP*GP*GP*CP*AP*UP*A)-3', ... | | Authors: | Lapkouski, M, Tian, L, Miller, J.T, Le Grice, S.F.J, Yang, W. | | Deposit date: | 2012-07-25 | | Release date: | 2013-01-16 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Complexes of HIV-1 RT, Nnrti and RNA/DNA Hybrid Reveal a Structure Compatible with RNA Degradation
Nat.Struct.Mol.Biol., 20, 2013
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4BAC
 | | prototype foamy virus strand transfer complexes on product DNA | | Descriptor: | 5'-D(*AP*GP*GP*AP*GP*CP*CP*AP*AP*GP*AP*CP*GP*GP *AP*TP*CP)-3', 5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP *TP*TP*GP*TP*AP)-3', DNA (38-MER), ... | | Authors: | Yin, Z, Lapkouski, M, Yang, W, Craigie, R. | | Deposit date: | 2012-09-12 | | Release date: | 2012-10-10 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.263 Å) | | Cite: | Assembly of Prototype Foamy Virus Strand Transfer Complexes on Product DNA Bypassing Catalysis of Integration.
Protein Sci., 21, 2012
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4B3Q
 | | Structures of HIV-1 RT and RNA-DNA Complex Reveal a Unique RT Conformation and Substrate Interface | | Descriptor: | 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, P51 RT, PRIMER DNA, ... | | Authors: | Lapkouski, M, Tian, L, Miller, J.T, Le Grice, S.F.J, Yang, W. | | Deposit date: | 2012-07-25 | | Release date: | 2013-01-16 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (5 Å) | | Cite: | Complexes of HIV-1 RT, Nnrti and RNA/DNA Hybrid Reveal a Structure Compatible with RNA Degradation
Nat.Struct.Mol.Biol., 20, 2013
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4B3P
 | | Structures of HIV-1 RT and RNA-DNA Complex Reveal a Unique RT Conformation and Substrate Interface | | Descriptor: | DNA, P51 RT, REVERSE TRANSCRIPTASE/RIBONUCLEASE H, ... | | Authors: | Lapkouski, M, Tian, L, Miller, J.T, Le Grice, S.F.J, Yang, W. | | Deposit date: | 2012-07-25 | | Release date: | 2013-01-16 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (4.839 Å) | | Cite: | Complexes of HIV-1 RT, Nnrti and RNA/DNA Hybrid Reveal a Structure Compatible with RNA Degradation
Nat.Struct.Mol.Biol., 20, 2013
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7SGL
 | | DNA-PK complex of DNA end processing | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA-dependent protein kinase catalytic subunit, Hairpin_1, ... | | Authors: | Liu, L, Li, J, Chen, X, Yang, W, Gellert, M. | | Deposit date: | 2021-10-06 | | Release date: | 2022-01-12 | | Last modified: | 2022-01-19 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Autophosphorylation transforms DNA-PK from protecting to processing DNA ends.
Mol.Cell, 82, 2022
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7SUD
 | | CryoEM structure of DNA-PK complex VIII | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA-dependent protein kinase catalytic subunit, MAGNESIUM ION, ... | | Authors: | Chen, X, Liu, L, Gellert, M, Yang, W. | | Deposit date: | 2021-11-16 | | Release date: | 2022-01-12 | | Last modified: | 2022-01-19 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Autophosphorylation transforms DNA-PK from protecting to processing DNA ends.
Mol.Cell, 82, 2022
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7SU3
 | | CryoEM structure of DNA-PK complex VII | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*AP*GP*CP*AP*GP*TP*AP*GP*AP*G)-3'), DNA (5'-D(*GP*CP*AP*TP*GP*CP*TP*CP*TP*AP*CP*TP*GP*CP*TP*TP*CP*GP*AP*TP*AP*TP*CP*G)-3'), ... | | Authors: | Chen, X, Liu, L, Gellert, M, Yang, W. | | Deposit date: | 2021-11-16 | | Release date: | 2022-01-12 | | Last modified: | 2022-01-19 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Autophosphorylation transforms DNA-PK from protecting to processing DNA ends.
Mol.Cell, 82, 2022
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3REZ
 | | glycoprotein GPIb variant | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, Platelet glycoprotein Ib beta chain, ... | | Authors: | McEwan, P.A, Yang, W, Carr, K.H, Mo, X, Zheng, X, Li, R, Emsley, J. | | Deposit date: | 2011-04-05 | | Release date: | 2012-02-15 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Quaternary organization of GPIb-IX complex and insights into Bernard-Soulier syndrome revealed by the structures of GPIb beta and a GPIb beta/GPIX chimera
Blood, 118, 2011
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3RJY
 | | Crystal Structure of Hyperthermophilic Endo-beta-1,4-glucanase in complex with substrate | | Descriptor: | Endoglucanase FnCel5A, PHOSPHATE ION, alpha-D-glucopyranose | | Authors: | Zheng, B, Yang, W, Zhao, X, Wang, Y, Lou, Z, Rao, Z, Feng, Y. | | Deposit date: | 2011-04-15 | | Release date: | 2012-02-08 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of hyperthermophilic Endo-beta-1,4-glucanase: Implications for catalytic mechanism and thermostability.
J.Biol.Chem., 287, 2012
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3RJX
 | | Crystal Structure of Hyperthermophilic Endo-Beta-1,4-glucanase | | Descriptor: | Endoglucanase FnCel5A | | Authors: | Zheng, B.S, Yang, W, Zhao, X.Y, Wang, Y.G, Lou, Z.Y, Rao, Z.H, Feng, Y. | | Deposit date: | 2011-04-15 | | Release date: | 2011-12-14 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of hyperthermophilic endo-beta-1,4-glucanase: implications for catalytic mechanism and thermostability.
J.Biol.Chem., 287, 2012
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3RFE
 | | Crystal structure of glycoprotein GPIb ectodomain | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, Platelet glycoprotein Ib beta chain, ... | | Authors: | McEwan, P.A, Yang, W, Carr, K.H, Mo, X, Zheng, X, Li, R, Emsley, J. | | Deposit date: | 2011-04-06 | | Release date: | 2011-12-21 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.245 Å) | | Cite: | Quaternary organization of GPIb-IX complex and insights into Bernard-Soulier syndrome revealed by the structures of GPIbbeta and a GPIbbeta/GPIX chimer
Blood, 118, 2011
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3SI8
 | | Human DNA polymerase eta - DNA ternary complex with the 5'T of a CPD in the active site (TT2) | | Descriptor: | (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol, 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, ... | | Authors: | Biertumpfel, C, Zhao, Y, Kondo, Y, Ramon-Maiques, S, Gregory, M, Lee, J.Y, Masutani, C, Lehmann, A.R, Hanaoka, F, Yang, W. | | Deposit date: | 2011-06-17 | | Release date: | 2011-08-03 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structure and mechanism of human DNA polymerase eta.
Nature, 465, 2010
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4MZD
 | | High resolution crystal structure of the nisin leader peptidase NisP from Lactococcus lactis | | Descriptor: | Nisin leader peptide-processing serine protease NisP | | Authors: | Rao, Z.H, Xu, Y.Y, Li, X, Yang, W. | | Deposit date: | 2013-09-30 | | Release date: | 2014-06-11 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | Structure of the nisin leader peptidase NisP revealing a C-terminal autocleavage activity.
Acta Crystallogr.,Sect.D, 70, 2014
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1XDT
 | | COMPLEX OF DIPHTHERIA TOXIN AND HEPARIN-BINDING EPIDERMAL GROWTH FACTOR | | Descriptor: | DIPHTHERIA TOXIN, HEPARIN-BINDING EPIDERMAL GROWTH FACTOR | | Authors: | Louie, G.V, Yang, W, Bowman, M.E, Choe, S. | | Deposit date: | 1997-11-18 | | Release date: | 1998-02-25 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Crystal structure of the complex of diphtheria toxin with an extracellular fragment of its receptor.
Mol.Cell, 1, 1997
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1X9Z
 | | Crystal structure of the MutL C-terminal domain | | Descriptor: | CHLORIDE ION, DNA mismatch repair protein mutL, GLYCEROL, ... | | Authors: | Guarne, A, Ramon-Maiques, S, Wolff, E.M, Ghirlando, R, Hu, X, Miller, J.H, Yang, W. | | Deposit date: | 2004-08-24 | | Release date: | 2004-10-26 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure of the MutL C-terminal domain: a model of intact MutL and its roles in mismatch repair
Embo J., 23, 2004
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1XRX
 | | Crystal structure of a DNA-binding protein | | Descriptor: | CALCIUM ION, SeqA protein | | Authors: | Guarne, A, Brendler, T, Zhao, Q, Ghirlando, R, Austin, S, Yang, W. | | Deposit date: | 2004-10-16 | | Release date: | 2005-05-10 | | Last modified: | 2013-03-06 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Crystal structure of a SeqA-N filament: implications for DNA replication and chromosome organization.
Embo J., 24, 2005
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1YQM
 | | Catalytically inactive human 8-oxoguanine glycosylase crosslinked to 7-deazaguanine containing DNA | | Descriptor: | 5'-D(P*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*CP*AP*(7GU)P*GP*TP*CP*TP*AP*C)-3', CALCIUM ION, ... | | Authors: | Banerjee, A, Yang, W, Karplus, M, Verdine, G.L. | | Deposit date: | 2005-02-02 | | Release date: | 2005-04-05 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA.
Nature, 434, 2005
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3LWO
 | | Structure of H/ACA RNP bound to a substrate RNA containing 5BrU | | Descriptor: | 5'-R(*GP*AP*GP*CP*GP*(5BU)P*GP*CP*GP*GP*UP*UP*U)-3', 50S ribosomal protein L7Ae, H/ACA RNA, ... | | Authors: | Zhou, J, Liang, B, Lv, C, Yang, W, Li, H. | | Deposit date: | 2010-02-24 | | Release date: | 2010-07-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.855 Å) | | Cite: | Glycosidic bond conformation preference plays a pivotal role in catalysis of RNA pseudouridylation: a combined simulation and structural study.
J.Mol.Biol., 401, 2010
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3LWP
 | | Structure of H/ACA RNP bound to a substrate RNA containing 5BrdU | | Descriptor: | 5'-R(*GP*AP*GP*CP*GP*(BRU)P*GP*CP*GP*GP*UP*UP*U)-3, 50S ribosomal protein L7Ae, H/ACA RNA, ... | | Authors: | Zhou, J, Liang, B, Lv, C, Yang, W, Li, H. | | Deposit date: | 2010-02-24 | | Release date: | 2010-07-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Glycosidic bond conformation preference plays a pivotal role in catalysis of RNA pseudouridylation: a combined simulation and structural study.
J.Mol.Biol., 401, 2010
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1YQK
 | | Human 8-oxoguanine glycosylase crosslinked with guanine containing DNA | | Descriptor: | 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*G)-3', 5'-D(P*CP*AP*GP*GP*TP*CP*TP*AP*C)-3', CALCIUM ION, ... | | Authors: | Banerjee, A, Yang, W, Karplus, M, Verdine, G.L. | | Deposit date: | 2005-02-01 | | Release date: | 2005-04-05 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA.
Nature, 434, 2005
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