2JUV
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![BU of 2juv by Molmil](/molmil-images/mine/2juv) | AbaA3-DKP-insulin | 分子名称: | Insulin A chain, Insulin B chain | 著者 | Huang, K, Chan, S, Hua, Q, Chu, Y, Wang, R, Klaproth, B, Jia, W, Whittaker, J, De Meyts, P, Nakagawa, S.H, Steiner, D.F, Katsoyannis, P.G, Weiss, M.A. | 登録日 | 2007-09-05 | 公開日 | 2007-10-16 | 最終更新日 | 2021-10-20 | 実験手法 | SOLUTION NMR | 主引用文献 | The A-chain of Insulin Contacts the Insert Domain of the Insulin Receptor: PHOTO-CROSS-LINKING AND MUTAGENESIS OF A DIABETES-RELATED CREVICE. J.Biol.Chem., 282, 2007
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1SUE
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![BU of 1sue by Molmil](/molmil-images/mine/1sue) | SUBTILISIN BPN' FROM BACILLUS AMYLOLIQUEFACIENS, MUTANT | 分子名称: | DIISOPROPYL PHOSPHONATE, SODIUM ION, SUBTILISIN BPN' | 著者 | Gallagher, D.T, Bryan, P, Pan, Q, Gilliland, G.L. | 登録日 | 1998-02-17 | 公開日 | 1998-10-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Mechanism of ionic strength dependence of crystal growth rates in a subtilisin variant. J.Cryst.Growth, 193, 1998
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4DDB
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![BU of 4ddb by Molmil](/molmil-images/mine/4ddb) | EVAL processed HEWL, cisplatin DMSO paratone pH 6.5 | 分子名称: | Cisplatin, DIMETHYL SULFOXIDE, Lysozyme C | 著者 | Tanley, S.W, Schreurs, A.M, Kroon-Batenburg, L.M, Meredith, J, Prendergast, R, Walsh, D, Bryant, P, Levy, C, Helliwell, J.R. | 登録日 | 2012-01-18 | 公開日 | 2012-04-25 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural studies of the effect that dimethyl sulfoxide (DMSO) has on cisplatin and carboplatin binding to histidine in a protein. Acta Crystallogr.,Sect.D, 68, 2012
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4DD2
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![BU of 4dd2 by Molmil](/molmil-images/mine/4dd2) | EVAL processed HEWL, carboplatin aqueous glycerol | 分子名称: | GLYCEROL, Lysozyme C | 著者 | Tanley, S.W, Schreurs, A.M, Kroon-Batenburg, L.M, Meredith, J, Prendergast, R, Walsh, D, Bryant, P, Levy, C, Helliwell, J.R. | 登録日 | 2012-01-18 | 公開日 | 2012-04-25 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structural studies of the effect that dimethyl sulfoxide (DMSO) has on cisplatin and carboplatin binding to histidine in a protein. Acta Crystallogr.,Sect.D, 68, 2012
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1ZXH
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![BU of 1zxh by Molmil](/molmil-images/mine/1zxh) | G311 mutant protein | 分子名称: | Immunoglobulin G binding protein G | 著者 | He, Y, Yeh, D.C, Alexander, P, Bryan, P.N, Orban, J. | 登録日 | 2005-06-08 | 公開日 | 2005-11-08 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR structures of IgG binding domains with artificially evolved high levels of sequence identity but different folds. Biochemistry, 44, 2005
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4DD0
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![BU of 4dd0 by Molmil](/molmil-images/mine/4dd0) | EVAL processed HEWL, cisplatin aqueous glycerol | 分子名称: | GLYCEROL, Lysozyme C | 著者 | Tanley, S.W, Schreurs, A.M, Kroon-Batenburg, L.M, Meredith, J, Prendergast, R, Walsh, D, Bryant, P, Levy, C, Helliwell, J.R. | 登録日 | 2012-01-18 | 公開日 | 2012-04-25 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural studies of the effect that dimethyl sulfoxide (DMSO) has on cisplatin and carboplatin binding to histidine in a protein. Acta Crystallogr.,Sect.D, 68, 2012
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4DD3
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![BU of 4dd3 by Molmil](/molmil-images/mine/4dd3) | EVAL processed HEWL, carboplatin aqueous paratone | 分子名称: | 2-methylprop-1-ene, CHLORIDE ION, Lysozyme C | 著者 | Tanley, S.W, Schreurs, A.M, Kroon-Batenburg, L.M, Meredith, J, Prendergast, R, Walsh, D, Bryant, P, Levy, C, Helliwell, J.R. | 登録日 | 2012-01-18 | 公開日 | 2012-04-25 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural studies of the effect that dimethyl sulfoxide (DMSO) has on cisplatin and carboplatin binding to histidine in a protein. Acta Crystallogr.,Sect.D, 68, 2012
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1ZXG
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![BU of 1zxg by Molmil](/molmil-images/mine/1zxg) | Solution structure of A219 | 分子名称: | Immunoglobulin G binding protein A | 著者 | He, Y, Yeh, D.C, Alexander, P, Bryan, P.N, Orban, J. | 登録日 | 2005-06-08 | 公開日 | 2005-11-08 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR structures of IgG binding domains with artificially evolved high levels of sequence identity but different folds. Biochemistry, 44, 2005
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1AJZ
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![BU of 1ajz by Molmil](/molmil-images/mine/1ajz) | STRUCTURE OF DIHYDROPTEROATE PYROPHOSPHORYLASE | 分子名称: | DIHYDROPTEROATE SYNTHASE, SULFATE ION | 著者 | Achari, A, Somers, D.O, Champness, J.N, Bryant, P.K, Rosemond, J, Stammers, D.K. | 登録日 | 1997-05-13 | 公開日 | 1998-05-13 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of the anti-bacterial sulfonamide drug target dihydropteroate synthase. Nat.Struct.Biol., 4, 1997
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1AJ2
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![BU of 1aj2 by Molmil](/molmil-images/mine/1aj2) | CRYSTAL STRUCTURE OF A BINARY COMPLEX OF E. COLI DIHYDROPTEROATE SYNTHASE | 分子名称: | DIHYDROPTEROATE SYNTHASE, SULFATE ION, [7,8-DIHYDRO-PTERIN-6-YL METHANYL]-PHOSPHONOPHOSPHATE | 著者 | Achari, A, Somers, D.O, Champness, J.N, Bryant, P.K, Rosemond, J, Stammers, D.K. | 登録日 | 1997-05-14 | 公開日 | 1998-05-20 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of the anti-bacterial sulfonamide drug target dihydropteroate synthase. Nat.Struct.Biol., 4, 1997
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1T1P
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![BU of 1t1p by Molmil](/molmil-images/mine/1t1p) | NMR STRUCTURE OF HUMAN INSULIN MUTANT HIS-B10-ASP, VAL-B12-THR, PRO-B28-LYS, LYS-B29-PRO, 15 STRUCTURES | 分子名称: | Insulin, insulin | 著者 | Huang, K, Xu, B, Hu, S.Q, Chu, Y.C, Hua, Q.X, Whittaker, J, Nakagawa, S.H, De Meyts, P, Katsoyannis, P.G, Weiss, M.A. | 登録日 | 2004-04-16 | 公開日 | 2004-08-10 | 最終更新日 | 2021-10-27 | 実験手法 | SOLUTION NMR | 主引用文献 | How Insulin Binds: the B-Chain alpha-Helix Contacts the L1 beta-Helix of the Insulin Receptor. J.Mol.Biol., 341, 2004
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2K9R
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![BU of 2k9r by Molmil](/molmil-images/mine/2k9r) | Enhancing the activity of insulin by stereospecific unfolding | 分子名称: | Insulin | 著者 | Hua, Q.X, Xu, B, Huang, K, Hu, S.Q, Nakarawa, S, Jia, W.H, Philips, N.F.P, Wittaker, L, Wittaker, J, Katsoyannis, P.G, Weiss, M.A. | 登録日 | 2008-10-23 | 公開日 | 2008-11-11 | 最終更新日 | 2021-10-20 | 実験手法 | SOLUTION NMR | 主引用文献 | Enhancing the Activity of a Protein by Stereospecific Unfolding: CONFORMATIONAL LIFE CYCLE OF INSULIN AND ITS EVOLUTIONARY ORIGINS. J.Biol.Chem., 284, 2009
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2K91
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![BU of 2k91 by Molmil](/molmil-images/mine/2k91) | Enhancing the activity of insulin by stereospecific unfolding | 分子名称: | Insulin | 著者 | Hua, Q.X, Xu, B, Huang, K, Hu, S.Q, Nakarawa, S, Jia, W.H, Philips, N.F.P, Wittaker, L, Wittaker, J, Katsoyannis, P.G, Weiss, M.A. | 登録日 | 2008-09-29 | 公開日 | 2008-11-18 | 最終更新日 | 2021-10-20 | 実験手法 | SOLUTION NMR | 主引用文献 | Enhancing the Activity of a Protein by Stereospecific Unfolding: CONFORMATIONAL LIFE CYCLE OF INSULIN AND ITS EVOLUTIONARY ORIGINS. J.Biol.Chem., 284, 2009
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2MH8
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![BU of 2mh8 by Molmil](/molmil-images/mine/2mh8) | GA-79-MBP cs-rosetta structures | 分子名称: | GA-79-MBP, maltose binding protein | 著者 | He, Y, Chen, Y, Porter, L, Bryan, P, Orban, J. | 登録日 | 2013-11-19 | 公開日 | 2015-04-08 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Subdomain interactions foster the design of two protein pairs with 80% sequence identity but different folds. Biophys.J., 108, 2015
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2LU1
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![BU of 2lu1 by Molmil](/molmil-images/mine/2lu1) | pfsub2 solution NMR structure | 分子名称: | Subtilase | 著者 | He, Y, Chen, Y, Ruan, B, O'Brochta, D, Bryan, P, Orban, J. | 登録日 | 2012-06-06 | 公開日 | 2012-10-03 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR structure of a sheddase inhibitor prodomain from the malarial parasite Plasmodium falciparum. Proteins, 80, 2012
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4QPC
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![BU of 4qpc by Molmil](/molmil-images/mine/4qpc) | Crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase (Y200A) from zebrafish | 分子名称: | 10-formyltetrahydrofolate dehydrogenase | 著者 | Lin, C.C, Chen, C.J, Fu, T.F, Chuankhayan, P, Kao, T.T, Chang, W.N. | 登録日 | 2014-06-23 | 公開日 | 2015-04-15 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.902 Å) | 主引用文献 | Structures of the hydrolase domain of zebrafish 10-formyltetrahydrofolate dehydrogenase and its complexes reveal a complete set of key residues for hydrolysis and product inhibition. Acta Crystallogr.,Sect.D, 71, 2015
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1XW7
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![BU of 1xw7 by Molmil](/molmil-images/mine/1xw7) | Diabetes-Associated Mutations in Human Insulin: Crystal Structure and Photo-Cross-Linking Studies of A-Chain Variant Insulin Wakayama | 分子名称: | CHLORIDE ION, Insulin, PHENOL, ... | 著者 | Wan, Z.L, Huang, K, Xu, B, Chu, Y.C, Hu, S.Q, Katsoyannis, P.G, Weiss, M.A. | 登録日 | 2004-10-29 | 公開日 | 2005-04-12 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Diabetes-associated mutations in human insulin: crystal structure and photo-cross-linking studies of a-chain variant insulin wakayama Biochemistry, 44, 2005
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1VKT
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![BU of 1vkt by Molmil](/molmil-images/mine/1vkt) | HUMAN INSULIN TWO DISULFIDE MODEL, NMR, 10 STRUCTURES | 分子名称: | INSULIN | 著者 | Hua, Q.X, Hu, S.Q, Frank, B.H, Jia, W.H, Chu, Y.C, Wang, S.H, Burke, G.T, Katsoyannis, P.G, Weiss, M.A. | 登録日 | 1996-10-14 | 公開日 | 1997-04-01 | 最終更新日 | 2021-11-03 | 実験手法 | SOLUTION NMR | 主引用文献 | Mapping the functional surface of insulin by design: structure and function of a novel A-chain analogue. J.Mol.Biol., 264, 1996
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2JMN
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![BU of 2jmn by Molmil](/molmil-images/mine/2jmn) | NMR structure of human insulin mutant His-B10-Asp, Pro-B28-Lys, Lys-B29-Pro, 20 structures | 分子名称: | Insulin A chain, Insulin B chain | 著者 | Hua, Q.X, Hu, S.Q, Frank, B.H, Jia, W.H, Chu, Y.C, Wang, S.H, Burke, G.T, Katsoyannis, P.G, Weiss, M.A. | 登録日 | 2006-11-21 | 公開日 | 2006-12-05 | 最終更新日 | 2023-12-20 | 実験手法 | SOLUTION NMR | 主引用文献 | Mapping the functional surface of insulin by design: structure and function of a novel A-chain analogue. J.Mol.Biol., 264, 1996
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2KJU
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![BU of 2kju by Molmil](/molmil-images/mine/2kju) | NMR structure of human insulin mutant glu-b21-d-glu, his-b10 asp pro-b28-lys, lys-b29-pro, 20 structures | 分子名称: | Insulin | 著者 | Hua, Q.X, Huang, K, Hu, S.Q, Katsoyanni, P, Weiss, M.A. | 登録日 | 2009-06-10 | 公開日 | 2010-06-16 | 最終更新日 | 2021-10-13 | 実験手法 | SOLUTION NMR | 主引用文献 | Acceleration of Protein Fibrillation by Chiral Destabilization of Beta-Turn To be Published
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2FS1
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![BU of 2fs1 by Molmil](/molmil-images/mine/2fs1) | solution structure of PSD-1 | 分子名称: | PSD-1 | 著者 | He, Y, Rozak, D.A, Sari, N, Chen, Y, Bryan, P, Orban, J. | 登録日 | 2006-01-20 | 公開日 | 2006-12-05 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure, dynamics, and stability variation in bacterial albumin binding modules: implications for species specificity. Biochemistry, 45, 2006
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