7BQ7
 
 | | Crystal structure of 2019-nCoV nsp16-nsp10 complex | | Descriptor: | 2'-O-methyltransferase, Non-structural protein 10, S-ADENOSYLMETHIONINE, ... | | Authors: | Yan, L.M, Huang, Y.C, Lou, Z.Y, Rao, Z.H. | | Deposit date: | 2020-03-24 | | Release date: | 2020-06-17 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.37 Å) | | Cite: | Crystal structure of 2019-nCoV nsp16-nsp10 complex
To Be Published
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3T34
 | | Arabidopsis thaliana dynamin-related protein 1A (AtDRP1A) in prefission state | | Descriptor: | Dynamin-related protein 1A, LINKER, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Yan, L.M, Ma, Y.Y, Sun, Y.N, Lou, Z.Y. | | Deposit date: | 2011-07-24 | | Release date: | 2012-06-06 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.405 Å) | | Cite: | Structural basis for mechanochemical role of Arabidopsis thaliana dynamin-related protein in membrane fission
J Mol Cell Biol, 3, 2011
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3T35
 | | Arabidopsis thaliana dynamin-related protein 1A in postfission state | | Descriptor: | Dynamin-related protein 1A, LINKER, GUANOSINE-5'-DIPHOSPHATE | | Authors: | Yan, L.M, Ma, Y.Y, Sun, Y.N, Lou, Z.Y. | | Deposit date: | 2011-07-24 | | Release date: | 2012-06-06 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.592 Å) | | Cite: | Structural basis for mechanochemical role of Arabidopsis thaliana dynamin-related protein in membrane fission
J Mol Cell Biol, 3, 2011
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6M5I
 | | Crystal structure of 2019-nCoV nsp7-nsp8c complex | | Descriptor: | Non-structural protein 7, Non-structural protein 8 | | Authors: | Yan, L.M, Ge, J, Zhao, Y, Lou, Z.Y, Rao, Z.H. | | Deposit date: | 2020-03-10 | | Release date: | 2020-06-17 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.496 Å) | | Cite: | Crystal structure of 2019-nCoV nsp7-nsp8c complex
To Be Published
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7EOZ
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8GWO
 | | A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analogue inhibitors | | Descriptor: | Helicase, Non-structural protein 7, Non-structural protein 8, ... | | Authors: | Yan, L.M, Huang, Y.C, Ge, J, Liu, Z.Y, Gao, Y, Rao, Z.H, Lou, Z.Y. | | Deposit date: | 2022-09-17 | | Release date: | 2022-11-30 | | Last modified: | 2024-01-24 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors.
Cell, 185, 2022
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8GWE
 | | SARS-CoV-2 E-RTC complex with RNA-nsp9 and GMPPNP | | Descriptor: | Helicase nsp13, MAGNESIUM ION, Non-structural protein 8, ... | | Authors: | Yan, L.M, Rao, Z.H, Lou, Z.Y. | | Deposit date: | 2022-09-16 | | Release date: | 2023-01-11 | | Last modified: | 2023-10-25 | | Method: | ELECTRON MICROSCOPY (2.66 Å) | | Cite: | A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors.
Cell, 185, 2022
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8GWB
 | | SARS-CoV-2 E-RTC complex with RNA-nsp9 | | Descriptor: | Helicase, MANGANESE (II) ION, Non-structural protein 7, ... | | Authors: | Yan, L.M, Rao, Z.H, Lou, Z.Y. | | Deposit date: | 2022-09-16 | | Release date: | 2022-12-07 | | Last modified: | 2023-10-25 | | Method: | ELECTRON MICROSCOPY (2.75 Å) | | Cite: | A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors.
Cell, 185, 2022
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8GWG
 | | A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analogue inhibitors | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Helicase, Non-structural protein 7, ... | | Authors: | Yan, L.M, Huang, Y.C, Ge, J, Liu, Z.Y, Gao, Y, Rao, Z.H, Lou, Z.Y. | | Deposit date: | 2022-09-17 | | Release date: | 2022-12-14 | | Method: | ELECTRON MICROSCOPY (3.37 Å) | | Cite: | A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors.
Cell, 185, 2022
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8GWN
 | | A mechanism for SARS-CoV-2 RNA capping and its inhibitor of AT-527 | | Descriptor: | Helicase, Non-structural protein 7, Non-structural protein 8, ... | | Authors: | Yan, L.M, Huang, Y.C, Ge, J, Liu, Z.Y, Gao, Y, Rao, Z.H, Lou, Z.Y. | | Deposit date: | 2022-09-17 | | Release date: | 2022-12-14 | | Last modified: | 2023-10-25 | | Method: | ELECTRON MICROSCOPY (3.38 Å) | | Cite: | A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors.
Cell, 185, 2022
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8GWI
 | | A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analogue inhibitors | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Helicase, Non-structural protein 7, ... | | Authors: | Yan, L.M, Huang, Y.C, Ge, J, Liu, Z.Y, Gao, Y, Rao, Z.H, Lou, Z.Y. | | Deposit date: | 2022-09-17 | | Release date: | 2022-12-14 | | Method: | ELECTRON MICROSCOPY (3.18 Å) | | Cite: | A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors.
Cell, 185, 2022
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8GWM
 | | SARS-CoV-2 E-RTC bound with MMP-nsp9 and GMPPNP | | Descriptor: | 2'-deoxy-2'-fluoro-2'-methyluridine 5'-(trihydrogen diphosphate), Helicase, Non-structural protein 7, ... | | Authors: | Yan, L.M, Rao, Z.H, Lou, Z.Y. | | Deposit date: | 2022-09-17 | | Release date: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (2.64 Å) | | Cite: | A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors.
Cell, 185, 2022
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8GWK
 | | SARS-CoV-2 RNA E-RTC complex with RMP-nsp9 and GMPPNP | | Descriptor: | Helicase, MAGNESIUM ION, Non-structural protein 7, ... | | Authors: | Yan, L.M, Huang, Y.C, Ge, J, Liu, Z.Y, Gao, Y, Rao, Z.H, Lou, Z.Y. | | Deposit date: | 2022-09-17 | | Release date: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (2.72 Å) | | Cite: | A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors.
Cell, 185, 2022
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7EGQ
 | | Co-transcriptional capping machineries in SARS-CoV-2 RTC: Coupling of N7-methyltransferase and 3'-5' exoribonuclease with polymerase reveals mechanisms for capping and proofreading | | Descriptor: | Helicase, MAGNESIUM ION, Non-structural protein 10, ... | | Authors: | Yan, L.M, Yang, Y.X, Li, M.Y, Zhang, Y, Zheng, L.T, Ge, J, Huang, Y.C, Liu, Z.Y, Wang, T, Gao, S, Zhang, R, Huang, Y.Y, Guddat, L.W, Gao, Y, Rao, Z.H, Lou, Z.Y. | | Deposit date: | 2021-03-25 | | Release date: | 2021-07-21 | | Method: | ELECTRON MICROSCOPY (3.35 Å) | | Cite: | Coupling of N7-methyltransferase and 3'-5' exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading.
Cell, 184, 2021
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3ULZ
 | | Crystal structure of apo BAK1 | | Descriptor: | BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 | | Authors: | Lou, Z.Y, Yan, L.M, Ma, Y.Y. | | Deposit date: | 2011-11-11 | | Release date: | 2012-11-21 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural basis for BAK1 activation
To be Published
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5BZ0
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5GO3
 | | Crystal structure of a di-nucleotide cyclase Vibrio mutant | | Descriptor: | Cyclic GMP-AMP synthase | | Authors: | Ming, Z.H, Wang, W, Xie, Y.C, Chen, Y.C, Yan, L.M, Lou, Z.Y. | | Deposit date: | 2016-07-26 | | Release date: | 2016-11-02 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of a di-nucleotide cyclase Vibrio mutant
To Be Published
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3MTV
 | | The Crystal Structure of the PRRSV Nonstructural Protein Nsp1 | | Descriptor: | Papain-like cysteine protease | | Authors: | Xue, F, Sun, Y.N, Yan, L.M, Zhao, C, Lou, Z.Y, Rao, Z.H. | | Deposit date: | 2010-04-30 | | Release date: | 2010-05-19 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The crystal structure of porcine reproductive and respiratory syndrome virus nonstructural protein Nsp1beta reveals a novel metal-dependent nuclease
J.Virol., 84, 2010
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5HZG
 | | The crystal structure of the strigolactone-induced AtD14-D3-ASK1 complex | | Descriptor: | (2Z)-2-methylbut-2-ene-1,4-diol, F-box/LRR-repeat MAX2 homolog, SKP1-like protein 1A, ... | | Authors: | Yao, R.F, Ming, Z.H, Yan, L.M, Rao, Z.H, Lou, Z.Y, Xie, D.X. | | Deposit date: | 2016-02-02 | | Release date: | 2016-08-03 | | Last modified: | 2016-08-31 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | DWARF14 is a non-canonical hormone receptor for strigolactone
Nature, 536, 2016
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5HYW
 | | The crystal structure of the D3-ASK1 complex | | Descriptor: | F-box/LRR-repeat MAX2 homolog, SKP1-like protein 1A | | Authors: | Yao, R.F, Ming, Z.H, Yan, L.M, Rao, Z.H, Lou, Z.Y, Xie, D.X. | | Deposit date: | 2016-02-02 | | Release date: | 2016-08-03 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.01 Å) | | Cite: | DWARF14 is a non-canonical hormone receptor for strigolactone
Nature, 536, 2016
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4R3D
 | | Crystal structure of MERS Coronavirus papain like protease | | Descriptor: | Non-structural protein 3, ZINC ION | | Authors: | Kong, L.Y, Wang, Q, Ming, Z.H, Shaw, N, Sun, Y.N, Yan, L.M, Lou, Z.Y, Rao, Z.H. | | Deposit date: | 2014-08-15 | | Release date: | 2015-08-19 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.818 Å) | | Cite: | The Crystal Structures of Middle East Respiratory Syndrome Coronavirus Papain-like Protease and Its Complex with an Inhibitor
To be Published
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3UIM
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6LP3
 | | Structural basis and functional analysis epo1-bem3p complex for bud growth | | Descriptor: | GTPase-activating protein BEM3, Uncharacterized protein YMR124W | | Authors: | Wang, J, Li, L, Ming, Z.H, Wu, L.J, Yan, L.M. | | Deposit date: | 2020-01-08 | | Release date: | 2021-04-28 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (3.547 Å) | | Cite: | Structural basis and functional analysis epo1-bem3p complex for bud growth
To Be Published
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7FAC
 | | Crystal Structure of C-terminus of the non-structural protein 2 from SARS coronavirus | | Descriptor: | Non-structural protein 2, ZINC ION | | Authors: | Li, Y.Y, Ren, Z.L, Bao, Z.H, Ming, Z.H, Yan, L.M, Lou, Z.Y, Rao, Z.H. | | Deposit date: | 2021-07-06 | | Release date: | 2022-08-10 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.71 Å) | | Cite: | The Life of SARS-CoV-2 Inside Cells: Replication-Transcription Complex Assembly and Function.
Annu.Rev.Biochem., 91, 2022
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7FA1
 | | Crystal Structure of N-terminus of the non-structural protein 2 from SARS coronavirus | | Descriptor: | Non-structural protein 2, ZINC ION | | Authors: | Li, Y.Y, Ren, Z.L, Bao, Z.H, Ming, Z.H, Yan, L.M, Lou, Z.Y, Rao, Z.H. | | Deposit date: | 2021-07-05 | | Release date: | 2022-08-10 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | The Life of SARS-CoV-2 Inside Cells: Replication-Transcription Complex Assembly and Function.
Annu.Rev.Biochem., 91, 2022
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