6KGT
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![BU of 6kgt by Molmil](/molmil-images/mine/6kgt) | Crystal structure of Penicillin binding protein 3 (PBP3) from Mycobacterium tuerculosis, complexed with faropenem | 分子名称: | (2R)-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-5-[(2R)-oxolan-2-yl]-2,3-dihydro-1,3-thiazole-4-carboxylic acid, COBALT (II) ION, Penicillin-binding protein PbpB | 著者 | Lu, Z.K, Zhang, A.L, Liu, X, Guddat, L, Yang, H.T, Rao, Z.H. | 登録日 | 2019-07-12 | 公開日 | 2020-03-11 | 実験手法 | X-RAY DIFFRACTION (2.308 Å) | 主引用文献 | Structures ofMycobacterium tuberculosisPenicillin-Binding Protein 3 in Complex with Fivebeta-Lactam Antibiotics Reveal Mechanism of Inactivation. Mol.Pharmacol., 97, 2020
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6KGU
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![BU of 6kgu by Molmil](/molmil-images/mine/6kgu) | Crystal structure of Penicillin binding protein 3 (PBP3) from Mycobacterium tuerculosis, complexed with aztreonam | 分子名称: | 2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl)-2-oxo-2-{[(2S,3S)-1-oxo-3-(sulfoamino)butan-2-yl]amino}ethylidene]amino}oxy)-2-methylpropanoic acid, COBALT (II) ION, Penicillin-binding protein PbpB | 著者 | Lu, Z.K, Zhang, A.L, Liu, X, Guddat, L, Yang, H.T, Rao, Z.H. | 登録日 | 2019-07-12 | 公開日 | 2020-03-11 | 実験手法 | X-RAY DIFFRACTION (2.106 Å) | 主引用文献 | Structures ofMycobacterium tuberculosisPenicillin-Binding Protein 3 in Complex with Fivebeta-Lactam Antibiotics Reveal Mechanism of Inactivation. Mol.Pharmacol., 97, 2020
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3O3K
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![BU of 3o3k by Molmil](/molmil-images/mine/3o3k) | Crystal structure of AF1382 from Archaeoglobus fulgidus | 分子名称: | Uncharacterized protein AF_1382 | 著者 | Zhu, J.-Y, Zhao, M, Fu, Z.-Q, Yang, H, Chang, J, Xu, H, Chen, L, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG) | 登録日 | 2010-07-24 | 公開日 | 2010-08-04 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of the Archaeoglobus fulgidus orphan ORF AF1382 determined by sulfur SAD from a moderately diffracting crystal. Acta Crystallogr.,Sect.D, 68, 2012
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6KGS
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![BU of 6kgs by Molmil](/molmil-images/mine/6kgs) | Crystal structure of Penicillin binding protein 3 (PBP3) from Mycobacterium tuerculosis, complexed with meropenem | 分子名称: | (4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid, COBALT (II) ION, Penicillin-binding protein PbpB | 著者 | Lu, Z.K, Zhang, A.L, Liu, X, Guddat, L, Yang, H.T, Rao, Z.H. | 登録日 | 2019-07-12 | 公開日 | 2020-03-11 | 実験手法 | X-RAY DIFFRACTION (2.309 Å) | 主引用文献 | Structures ofMycobacterium tuberculosisPenicillin-Binding Protein 3 in Complex with Fivebeta-Lactam Antibiotics Reveal Mechanism of Inactivation. Mol.Pharmacol., 97, 2020
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6KGW
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![BU of 6kgw by Molmil](/molmil-images/mine/6kgw) | Crystal structure of Penicillin binding protein 3 (PBP3) from Mycobacterium tuerculosis, complexed with ampicillin | 分子名称: | (2R,4S)-2-[(1R)-1-{[(2R)-2-amino-2-phenylacetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, COBALT (II) ION, Penicillin-binding protein PbpB | 著者 | Lu, Z.K, Zhang, A.L, Liu, X, Guddat, L, Yang, H.T, Rao, Z.H. | 登録日 | 2019-07-12 | 公開日 | 2020-03-11 | 実験手法 | X-RAY DIFFRACTION (2.407 Å) | 主引用文献 | Structures ofMycobacterium tuberculosisPenicillin-Binding Protein 3 in Complex with Fivebeta-Lactam Antibiotics Reveal Mechanism of Inactivation. Mol.Pharmacol., 97, 2020
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6KGV
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![BU of 6kgv by Molmil](/molmil-images/mine/6kgv) | Crystal structure of Penicillin binding protein 3 (PBP3) from Mycobacterium tuerculosis, complexed with amoxicillin | 分子名称: | 2-{1-[2-AMINO-2-(4-HYDROXY-PHENYL)-ACETYLAMINO]-2-OXO-ETHYL}-5,5-DIMETHYL-THIAZOLIDINE-4-CARBOXYLIC ACID, COBALT (II) ION, Penicillin-binding protein PbpB | 著者 | Lu, Z.K, Zhang, A.L, Liu, X, Guddat, L, Yang, H.T, Rao, Z.H. | 登録日 | 2019-07-12 | 公開日 | 2020-03-11 | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | 主引用文献 | Structures ofMycobacterium tuberculosisPenicillin-Binding Protein 3 in Complex with Fivebeta-Lactam Antibiotics Reveal Mechanism of Inactivation. Mol.Pharmacol., 97, 2020
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2Q6F
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![BU of 2q6f by Molmil](/molmil-images/mine/2q6f) | Crystal structure of infectious bronchitis virus (IBV) main protease in complex with a Michael acceptor inhibitor N3 | 分子名称: | Infectious bronchitis virus (IBV) main protease, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE | 著者 | Xue, X.Y, Yang, H.T, Xue, F, Bartlam, M, Rao, Z.H. | 登録日 | 2007-06-05 | 公開日 | 2008-02-12 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structures of two coronavirus main proteases: implications for substrate binding and antiviral drug design. J.Virol., 82, 2008
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2Q62
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![BU of 2q62 by Molmil](/molmil-images/mine/2q62) | Crystal Structure of ArsH from Sinorhizobium meliloti | 分子名称: | SULFATE ION, arsH | 著者 | Ye, J, Yang, H, Bhattacharjee, H, Rosen, B.P. | 登録日 | 2007-06-04 | 公開日 | 2007-12-11 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of the flavoprotein ArsH from Sinorhizobium meliloti FEBS Lett., 581, 2007
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2Q6D
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![BU of 2q6d by Molmil](/molmil-images/mine/2q6d) | Crystal structure of infectious bronchitis virus (IBV) main protease | 分子名称: | Infectious bronchitis virus (IBV) main protease | 著者 | Xue, X.Y, Yang, H.T, Xue, F, Bartlam, M, Rao, Z.H. | 登録日 | 2007-06-04 | 公開日 | 2008-02-12 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structures of two coronavirus main proteases: implications for substrate binding and antiviral drug design. J.Virol., 82, 2008
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8YEW
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![BU of 8yew by Molmil](/molmil-images/mine/8yew) | TRIP4 ASCH domain in unliganded form | 分子名称: | Activating signal cointegrator 1 | 著者 | Ding, J, Yang, H, Hu, C. | 登録日 | 2024-02-23 | 公開日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Biochemical and structural characterization of the DNA-binding properties of human TRIP4 ASCH domain reveals insights into its functional role. Structure, 2024
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8YFI
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![BU of 8yfi by Molmil](/molmil-images/mine/8yfi) | |
8YFJ
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7E3L
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![BU of 7e3l by Molmil](/molmil-images/mine/7e3l) | Ultrapotent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 58G6 heavy chain, 58G6 light chain, ... | 著者 | Guo, H, Li, T, Liu, F, Gao, Y, Ji, X, Yang, H. | 登録日 | 2021-02-09 | 公開日 | 2021-09-15 | 最終更新日 | 2022-03-02 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Potent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants. Nat Commun, 12, 2021
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7E3K
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![BU of 7e3k by Molmil](/molmil-images/mine/7e3k) | Ultrapotent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants | 分子名称: | 13G9 heavy chain, 13G9 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Guo, H, Li, T, Liu, F, Gao, Y, Ji, X, Yang, H. | 登録日 | 2021-02-09 | 公開日 | 2021-09-15 | 最終更新日 | 2022-03-02 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Potent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants. Nat Commun, 12, 2021
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7E5X
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7WS1
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![BU of 7ws1 by Molmil](/molmil-images/mine/7ws1) | Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 510A5 heavy chain, ... | 著者 | Guo, H, Gao, Y, Ji, X, Yang, H. | 登録日 | 2022-01-28 | 公開日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structures of Omicron spike complexes and implications for neutralizing antibody development. Cell Rep, 39, 2022
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7ESX
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![BU of 7esx by Molmil](/molmil-images/mine/7esx) | Crystal structure of Wolbachia cytoplasmic incompatibility factor CidA from wPip | 分子名称: | Bacteria factor 1 | 著者 | Xiao, Y.J, Wang, W, Chen, X, Ji, X.Y, Yang, H.T. | 登録日 | 2021-05-12 | 公開日 | 2021-11-10 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural and mechanistic insights into the complexes formed by Wolbachia cytoplasmic incompatibility factors. Proc.Natl.Acad.Sci.USA, 118, 2021
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7ESY
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![BU of 7esy by Molmil](/molmil-images/mine/7esy) | Crystal structure of the complex formed by Wolbachia cytoplasmic incompatibility factors CidA and CidBND1-ND2 from wPip | 分子名称: | Bacteria factor 1, CALCIUM ION, ULP_PROTEASE domain-containing protein | 著者 | Xiao, Y.J, Wang, W, Chen, X, Ji, X.Y, Yang, H.T. | 登録日 | 2021-05-12 | 公開日 | 2021-11-10 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.297 Å) | 主引用文献 | Structural and mechanistic insights into the complexes formed by Wolbachia cytoplasmic incompatibility factors. Proc.Natl.Acad.Sci.USA, 118, 2021
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5H2C
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![BU of 5h2c by Molmil](/molmil-images/mine/5h2c) | Crystal structure of Saccharomyces cerevisiae Osh1 ANK - Nvj1 | 分子名称: | Nucleus-vacuole junction protein 1, Oxysterol-binding protein homolog 1 | 著者 | Im, Y.J, Manik, M.K, Yang, H.S, Tong, J.S. | 登録日 | 2016-10-14 | 公開日 | 2017-05-10 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.508 Å) | 主引用文献 | Structure of Yeast OSBP-Related Protein Osh1 Reveals Key Determinants for Lipid Transport and Protein Targeting at the Nucleus-Vacuole Junction Structure, 25, 2017
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5H2D
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![BU of 5h2d by Molmil](/molmil-images/mine/5h2d) | Crystal structure of Osh1 ORD domain in complex with ergosterol | 分子名称: | ERGOSTEROL, KLLA0C04147p, SULFATE ION | 著者 | Im, Y.J, Manik, M.K, Yang, H.S, Tong, J.S. | 登録日 | 2016-10-14 | 公開日 | 2017-05-10 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure of Yeast OSBP-Related Protein Osh1 Reveals Key Determinants for Lipid Transport and Protein Targeting at the Nucleus-Vacuole Junction Structure, 25, 2017
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5WBU
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![BU of 5wbu by Molmil](/molmil-images/mine/5wbu) | |
7WS8
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![BU of 7ws8 by Molmil](/molmil-images/mine/7ws8) | Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | 著者 | Guo, H, Gao, Y, Ji, X, Yang, H. | 登録日 | 2022-01-28 | 公開日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structures of Omicron spike complexes and implications for neutralizing antibody development. Cell Rep, 39, 2022
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7WS0
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![BU of 7ws0 by Molmil](/molmil-images/mine/7ws0) | Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 510A5 heavy chain, ... | 著者 | Guo, H, Gao, Y, Ji, X, Yang, H. | 登録日 | 2022-01-28 | 公開日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structures of Omicron spike complexes and implications for neutralizing antibody development. Cell Rep, 39, 2022
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7WS6
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![BU of 7ws6 by Molmil](/molmil-images/mine/7ws6) | Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development | 分子名称: | 510A5 heavy chain, 510A5 light chain, Spike protein S1 | 著者 | Guo, H, Gao, Y, Ji, X, Yang, H. | 登録日 | 2022-01-28 | 公開日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structures of Omicron spike complexes and implications for neutralizing antibody development. Cell Rep, 39, 2022
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7WSA
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![BU of 7wsa by Molmil](/molmil-images/mine/7wsa) | Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike protein S1 | 著者 | Guo, H, Gao, Y, Ji, X, Yang, H. | 登録日 | 2022-01-28 | 公開日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structures of Omicron spike complexes and implications for neutralizing antibody development. Cell Rep, 39, 2022
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