4OTO
 
 | | Crystal structure of the S505W mutant of TAL effector dHax3 | | Descriptor: | DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*TP*AP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*TP*AP*TP*CP*TP*CP*TP*CP*T)-3'), Hax3 | | Authors: | Deng, D, Wu, J.P, Yan, C.Y, Pan, X.J, Yan, N. | | Deposit date: | 2014-02-14 | | Release date: | 2014-05-28 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.588 Å) | | Cite: | Revisiting the TALE repeat
Protein Cell, 5, 2014
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4OSS
 | | Crystal structure of the S505Q mutant of TAL effector dHax3 | | Descriptor: | DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*CP*AP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*TP*GP*TP*CP*TP*CP*TP*CP*T)-3'), Hax3 | | Authors: | Deng, D, Wu, J.P, Yan, C.Y, Pan, X.J, Yan, N. | | Deposit date: | 2014-02-13 | | Release date: | 2014-05-28 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.397 Å) | | Cite: | Revisiting the TALE repeat
Protein Cell, 5, 2014
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4OSQ
 | | Crystal structure of the S505R mutant of TAL effector dHax3 | | Descriptor: | DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*TP*AP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*TP*GP*TP*CP*TP*CP*TP*CP*T)-3'), Hax3, ... | | Authors: | Deng, D, Wu, J.P, Yan, C.Y, Pan, X.J, Yan, N. | | Deposit date: | 2014-02-13 | | Release date: | 2014-05-28 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.256 Å) | | Cite: | Revisiting the TALE repeat
Protein Cell, 5, 2014
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4OSR
 | | Crystal structure of the S505K mutant of TAL effector dHax3 | | Descriptor: | DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*TP*AP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*TP*GP*TP*CP*TP*CP*TP*CP*T)-3'), Hax3 | | Authors: | Deng, D, Wu, J.P, Yan, C.Y, Pan, X.J, Yan, N. | | Deposit date: | 2014-02-13 | | Release date: | 2014-05-28 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.944 Å) | | Cite: | Revisiting the TALE repeat
Protein Cell, 5, 2014
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4OSH
 | | Crystal structure of the TAL effector dHax3 with NI RVD at 2.2 angstrom resolution | | Descriptor: | DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*TP*AP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*TP*AP*TP*CP*TP*CP*TP*CP*T)-3'), Hax3 | | Authors: | Deng, D, Wu, J.P, Yan, C.Y, Pan, X.J, Yan, N. | | Deposit date: | 2014-02-13 | | Release date: | 2014-05-28 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.201 Å) | | Cite: | Revisiting the TALE repeat
Protein Cell, 5, 2014
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4OSW
 | | Crystal structure of the S505E mutant of TAL effector dHax3 | | Descriptor: | DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*TP*AP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*TP*AP*TP*CP*TP*CP*TP*CP*T)-3'), Hax3, ... | | Authors: | Deng, D, Wu, J.P, Yan, C.Y, Pan, X.J, Yan, N. | | Deposit date: | 2014-02-13 | | Release date: | 2014-05-28 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.302 Å) | | Cite: | Revisiting the TALE repeat
Protein Cell, 5, 2014
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4HYG
 | | Structure of a presenilin family intramembrane aspartate protease in C222 space group | | Descriptor: | Putative uncharacterized protein | | Authors: | Li, X, Dang, S, Yan, C, Wang, J, Shi, Y. | | Deposit date: | 2012-11-13 | | Release date: | 2012-12-19 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (3.32 Å) | | Cite: | Structure of a presenilin family intramembrane aspartate protease
Nature, 493, 2013
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4M57
 | | Crystal structure of the pentatricopeptide repeat protein PPR10 from maize | | Descriptor: | Chloroplast pentatricopeptide repeat protein 10 | | Authors: | Yin, P, Li, Q, Yan, C, Liu, Y, Yan, N. | | Deposit date: | 2013-08-08 | | Release date: | 2013-10-30 | | Last modified: | 2013-12-18 | | Method: | X-RAY DIFFRACTION (2.86 Å) | | Cite: | Structural basis for the modular recognition of single-stranded RNA by PPR proteins.
Nature, 504, 2013
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4HYD
 | | Structure of a presenilin family intramembrane aspartate protease in C2221 space group | | Descriptor: | Putative uncharacterized protein | | Authors: | Li, X, Dang, S, Yan, C, Wang, J, Shi, Y. | | Deposit date: | 2012-11-13 | | Release date: | 2012-12-19 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Structure of a presenilin family intramembrane aspartate protease
Nature, 493, 2013
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4HYC
 | | Structure of a presenilin family intramembrane aspartate protease in P2 space group | | Descriptor: | Putative uncharacterized protein | | Authors: | Li, X, Dang, S, Yan, C, Wang, J, Shi, Y. | | Deposit date: | 2012-11-13 | | Release date: | 2012-12-19 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (3.95 Å) | | Cite: | Structure of a presenilin family intramembrane aspartate protease
Nature, 493, 2013
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7ETW
 | | Cryo-EM structure of Scap/Insig complex in the present of digitonin. | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Digitonin, Insulin-induced gene 2 protein, ... | | Authors: | Yan, R, Cao, P, Song, W, Li, Y, Wang, T, Qian, H, Yan, C, Yan, N. | | Deposit date: | 2021-05-14 | | Release date: | 2021-06-23 | | Last modified: | 2022-03-02 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structural basis for sterol sensing by Scap and Insig
Cell Rep, 35, 2021
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4ITJ
 | | Crystal structure of RIP1 kinase in complex with necrostatin-4 | | Descriptor: | IODIDE ION, N-[(1S)-1-(2-chloro-6-fluorophenyl)ethyl]-5-cyano-1-methyl-1H-pyrrole-2-carboxamide, Receptor-interacting serine/threonine-protein kinase 1 | | Authors: | Xie, T, Peng, W, Liu, Y, Yan, C, Shi, Y. | | Deposit date: | 2013-01-18 | | Release date: | 2013-03-13 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural Basis of RIP1 Inhibition by Necrostatins.
Structure, 21, 2013
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4ITH
 | | Crystal structure of RIP1 kinase in complex with necrostatin-1 analog | | Descriptor: | (5R)-5-[(7-chloro-1H-indol-3-yl)methyl]-3-methylimidazolidine-2,4-dione, IODIDE ION, Receptor-interacting serine/threonine-protein kinase 1, ... | | Authors: | Xie, T, Peng, W, Liu, Y, Yan, C, Shi, Y. | | Deposit date: | 2013-01-18 | | Release date: | 2013-03-13 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structural Basis of RIP1 Inhibition by Necrostatins.
Structure, 21, 2013
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6URS
 | | Sleeping Beauty transposase PAI subdomain mutant - H19Y | | Descriptor: | Sleeping Beauty transposase PAI subdomain | | Authors: | Nesmelova, I.V, Leighton, G.O, Yan, C, Lustig, J, Corona, R.I, Guo, J.T, Ivics, Z. | | Deposit date: | 2019-10-24 | | Release date: | 2020-10-28 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | H19Y mutation in the primary DNA-recognition subdomain of the Sleeping Beauty transposase improves structural stability, transposon DNA-binding and transposition
To Be Published
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8GYO
 | | Inner channel lipids regulated gating mechanism of human pannexins. | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Digitonin, ... | | Authors: | Cong, Y, Jin, X, Kong, F, Yan, C. | | Deposit date: | 2022-09-23 | | Release date: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Inner channel lipids regulated gating mechanism of human pannexins.
To Be Published
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8GYQ
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4ITI
 | | Crystal structure of RIP1 kinase in complex with necrostatin-3 analog | | Descriptor: | 1-{(3S,3aS)-3-[3-fluoro-4-(trifluoromethoxy)phenyl]-8-methoxy-3,3a,4,5-tetrahydro-2H-benzo[g]indazol-2-yl}-2-hydroxyethanone, Receptor-interacting serine/threonine-protein kinase 1 | | Authors: | Xie, T, Peng, W, Liu, Y, Yan, C, Shi, Y. | | Deposit date: | 2013-01-18 | | Release date: | 2013-03-13 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.86 Å) | | Cite: | Structural Basis of RIP1 Inhibition by Necrostatins.
Structure, 21, 2013
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3UDB
 | | Crystal structure of SnRK2.6 | | Descriptor: | CHLORIDE ION, Serine/threonine-protein kinase SRK2E | | Authors: | Xie, T, Ren, R, Pang, Y, Yan, C. | | Deposit date: | 2011-10-27 | | Release date: | 2011-11-16 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.567 Å) | | Cite: | Molecular mechanism for the inhibition of a critical component in the Arabidopsis thaliana abscisic acid signal transduction pathways, SnRK2.6, by the protein phosphatase ABI1
to be published
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4LGI
 | | N-terminal truncated NleC structure | | Descriptor: | Uncharacterized protein | | Authors: | Li, W.Q, Liu, Y.X, Sheng, X.L, Yan, C.Y, Wang, J.W. | | Deposit date: | 2013-06-28 | | Release date: | 2014-01-15 | | Last modified: | 2015-02-25 | | Method: | X-RAY DIFFRACTION (2.301 Å) | | Cite: | Structure and mechanism of a type III secretion protease, NleC
Acta Crystallogr.,Sect.D, 70, 2014
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8HFE
 | | Cryo-EM structure of human norepinephrine transporter NET in an inward-open state at resolution of 2.5 angstrom | | Descriptor: | CHLORIDE ION, Sodium-dependent noradrenaline transporter | | Authors: | Tan, J, Xiao, Y, Kong, F, Lei, J, Yuan, Y, Yan, C. | | Deposit date: | 2022-11-10 | | Release date: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Molecular basis for the reuptake and inhibition of human norepinephrine transporter
To Be Published
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8HFF
 | | Cryo-EM structure of human norepinephrine transporter NET in the presence of norepinephrine in an inward-open state at resolution of 2.9 angstrom. | | Descriptor: | L-NOREPINEPHRINE, Sodium-dependent noradrenaline transporter | | Authors: | Tan, J, Xiao, Y, Kong, F, Lei, J, Yuan, Y, Yan, C. | | Deposit date: | 2022-11-10 | | Release date: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (2.86 Å) | | Cite: | Molecular basis for the reuptake and inhibition of human norepinephrine transporter
To Be Published
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8HFL
 | | Cryo-EM structure of human norepinephrine transporter NET in the presence of the antidepressant bupropion in an inward-open state at resolution of 3.0 angstrom. | | Descriptor: | Bupropion, CHLORIDE ION, Sodium-dependent noradrenaline transporter | | Authors: | Tan, J, Xiao, Y, Kong, F, Lei, J, Yuan, Y, Yan, C. | | Deposit date: | 2022-11-11 | | Release date: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Molecular basis for the reuptake and inhibition of human norepinephrine transporter
To Be Published
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5GMK
 | | Cryo-EM structure of the Catalytic Step I spliceosome (C complex) at 3.4 angstrom resolution | | Descriptor: | 5'-Exon, 5'-Splicing Site, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Wan, R, Yan, C, Bai, R, Huang, G, Shi, Y. | | Deposit date: | 2016-07-14 | | Release date: | 2016-08-17 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structure of a yeast catalytic step I spliceosome at 3.4 angstrom resolution
Science, 353, 2016
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8HFI
 | | Cryo-EM structure of human norepinephrine transporter NET in the presence of the antidepressant desipramine in an inward-open state at resolution of 2.5 angstrom. | | Descriptor: | 3-(10,11-DIHYDRO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N-METHYLPROPAN-1-AMINE, CHLORIDE ION, Sodium-dependent noradrenaline transporter | | Authors: | Tan, J, Xiao, Y, Kong, F, Lei, J, Yuan, Y, Yan, C. | | Deposit date: | 2022-11-10 | | Release date: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Molecular basis for the reuptake and inhibition of human norepinephrine transporter
To Be Published
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8HFG
 | | Cryo-EM structure of human norepinephrine transporter NET in the presence of dopamine in an inward-open state at resolution of 3.0 angstrom. | | Descriptor: | CHLORIDE ION, L-DOPAMINE, Sodium-dependent noradrenaline transporter | | Authors: | Tan, J, Xiao, Y, Kong, F, Lei, J, Yuan, Y, Yan, C. | | Deposit date: | 2022-11-10 | | Release date: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Molecular basis for the reuptake and inhibition of human norepinephrine transporter
To Be Published
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