4O79
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4o79 by Molmil](/molmil-images/mine/4o79) | Crystal Structure of Ascorbate-bound Cytochrome b561, crystal soaked in 1 M L-ascorbate for 10 minutes | 分子名称: | ASCORBIC ACID, PROTOPORPHYRIN IX CONTAINING FE, Probable transmembrane ascorbate ferrireductase 2, ... | 著者 | Lu, P, Ma, D, Yan, C, Gong, X, Du, M, Shi, Y. | 登録日 | 2013-12-24 | 公開日 | 2014-02-05 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.003 Å) | 主引用文献 | Structure and mechanism of a eukaryotic transmembrane ascorbate-dependent oxidoreductase Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
6LK8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lk8 by Molmil](/molmil-images/mine/6lk8) | Structure of Xenopus laevis Cytoplasmic Ring subunit. | 分子名称: | GATOR complex protein SEC13, MGC154553 protein, MGC83295 protein, ... | 著者 | Shi, Y, Huang, G, Yan, C, Zhang, Y. | 登録日 | 2019-12-18 | 公開日 | 2021-07-21 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (5.5 Å) | 主引用文献 | Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex by cryo-electron microscopy single particle analysis. Cell Res., 30, 2020
|
|
4M78
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4m78 by Molmil](/molmil-images/mine/4m78) | Crystal structure of Lsm2-8 complex, space group P21 | 分子名称: | U6 snRNA-associated Sm-like protein LSm2, U6 snRNA-associated Sm-like protein LSm3, U6 snRNA-associated Sm-like protein LSm4, ... | 著者 | Zhou, L, Hang, J, Zhou, Y, Wan, R, Lu, G, Yan, C, Shi, Y. | 登録日 | 2013-08-12 | 公開日 | 2013-11-13 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.794 Å) | 主引用文献 | Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA. Nature, 506, 2014
|
|
4M68
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4m68 by Molmil](/molmil-images/mine/4m68) | Crystal structure of the mouse MLKL kinase-like domain | 分子名称: | GLYCEROL, Mixed lineage kinase domain-like protein | 著者 | Xie, T, Peng, W, Yan, C, Wu, J, Shi, Y. | 登録日 | 2013-08-09 | 公開日 | 2013-10-16 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.696 Å) | 主引用文献 | Structural Insights into RIP3-Mediated Necroptotic Signaling Cell Rep, 5, 2013
|
|
4ITJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4itj by Molmil](/molmil-images/mine/4itj) | Crystal structure of RIP1 kinase in complex with necrostatin-4 | 分子名称: | IODIDE ION, N-[(1S)-1-(2-chloro-6-fluorophenyl)ethyl]-5-cyano-1-methyl-1H-pyrrole-2-carboxamide, Receptor-interacting serine/threonine-protein kinase 1 | 著者 | Xie, T, Peng, W, Liu, Y, Yan, C, Shi, Y. | 登録日 | 2013-01-18 | 公開日 | 2013-03-13 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Basis of RIP1 Inhibition by Necrostatins. Structure, 21, 2013
|
|
4ITI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4iti by Molmil](/molmil-images/mine/4iti) | Crystal structure of RIP1 kinase in complex with necrostatin-3 analog | 分子名称: | 1-{(3S,3aS)-3-[3-fluoro-4-(trifluoromethoxy)phenyl]-8-methoxy-3,3a,4,5-tetrahydro-2H-benzo[g]indazol-2-yl}-2-hydroxyethanone, Receptor-interacting serine/threonine-protein kinase 1 | 著者 | Xie, T, Peng, W, Liu, Y, Yan, C, Shi, Y. | 登録日 | 2013-01-18 | 公開日 | 2013-03-13 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | 主引用文献 | Structural Basis of RIP1 Inhibition by Necrostatins. Structure, 21, 2013
|
|
4M75
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4m75 by Molmil](/molmil-images/mine/4m75) | Crystal structure of Lsm1-7 complex | 分子名称: | CHLORIDE ION, U6 snRNA-associated Sm-like protein Lsm1, U6 snRNA-associated Sm-like protein Lsm2, ... | 著者 | Zhou, L, Hang, J, Zhou, Y, Wan, R, Lu, G, Yan, C, Shi, Y. | 登録日 | 2013-08-12 | 公開日 | 2013-10-23 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA. Nature, 506, 2014
|
|
4ITH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ith by Molmil](/molmil-images/mine/4ith) | Crystal structure of RIP1 kinase in complex with necrostatin-1 analog | 分子名称: | (5R)-5-[(7-chloro-1H-indol-3-yl)methyl]-3-methylimidazolidine-2,4-dione, IODIDE ION, Receptor-interacting serine/threonine-protein kinase 1, ... | 著者 | Xie, T, Peng, W, Liu, Y, Yan, C, Shi, Y. | 登録日 | 2013-01-18 | 公開日 | 2013-03-13 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural Basis of RIP1 Inhibition by Necrostatins. Structure, 21, 2013
|
|
4M77
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4m77 by Molmil](/molmil-images/mine/4m77) | Crystal structure of Lsm2-8 complex, space group I212121 | 分子名称: | U6 snRNA-associated Sm-like protein LSm2, U6 snRNA-associated Sm-like protein LSm3, U6 snRNA-associated Sm-like protein LSm4, ... | 著者 | Zhou, L, Hang, J, Zhou, Y, Wan, R, Lu, G, Yan, C, Shi, Y. | 登録日 | 2013-08-12 | 公開日 | 2013-11-13 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.111 Å) | 主引用文献 | Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA. Nature, 506, 2014
|
|
4M67
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4m67 by Molmil](/molmil-images/mine/4m67) | Crystal structure of the human MLKL kinase-like domain | 分子名称: | Mixed lineage kinase domain-like protein | 著者 | Xie, T, Peng, W, Yan, C, Wu, J, Shi, Y. | 登録日 | 2013-08-09 | 公開日 | 2013-10-16 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Insights into RIP3-Mediated Necroptotic Signaling Cell Rep, 5, 2013
|
|
5YZG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5yzg by Molmil](/molmil-images/mine/5yzg) | The Cryo-EM Structure of Human Catalytic Step I Spliceosome (C complex) at 4.1 angstrom resolution | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Zhan, X, Yan, C, Zhang, X, Lei, J, Shi, Y. | 登録日 | 2017-12-14 | 公開日 | 2018-08-08 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structure of a human catalytic step I spliceosome Science, 359, 2018
|
|
5XJC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xjc by Molmil](/molmil-images/mine/5xjc) | Cryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstrom | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Zhang, X, Yan, C, Hang, J, Finci, I.L, Lei, J, Shi, Y. | 登録日 | 2017-04-30 | 公開日 | 2017-07-05 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | An Atomic Structure of the Human Spliceosome Cell, 169, 2017
|
|
6LYY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lyy by Molmil](/molmil-images/mine/6lyy) | Cryo-EM structure of the human MCT1/Basigin-2 complex in the presence of anti-cancer drug candidate AZD3965 in the outward-open conformation. | 分子名称: | 3-methyl-5-[[(4~{R})-4-methyl-4-oxidanyl-1,2-oxazolidin-2-yl]carbonyl]-6-[[5-methyl-3-(trifluoromethyl)-1~{H}-pyrazol-4-yl]methyl]-1-propan-2-yl-thieno[2,3-d]pyrimidine-2,4-dione, Basigin, Monocarboxylate transporter 1 | 著者 | Wang, N, Jiang, X, Zhang, S, Zhu, A, Yuan, Y, Lei, J, Yan, C. | 登録日 | 2020-02-16 | 公開日 | 2020-12-23 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis of human monocarboxylate transporter 1 inhibition by anti-cancer drug candidates. Cell, 184, 2021
|
|
5YLZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ylz by Molmil](/molmil-images/mine/5ylz) | Cryo-EM Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae at 3.6 angstrom | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | 著者 | Wan, R, Yan, C, Bai, R, Lei, J, Shi, Y. | 登録日 | 2017-10-20 | 公開日 | 2018-07-18 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae Cell, 171, 2017
|
|
6LZ0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lz0 by Molmil](/molmil-images/mine/6lz0) | Cryo-EM structure of human MCT1 in complex with Basigin-2 in the presence of lactate | 分子名称: | (2S)-2-HYDROXYPROPANOIC ACID, Basigin, Monocarboxylate transporter 1 | 著者 | Wang, N, Jiang, X, Zhang, S, Zhu, A, Yuan, Y, Lei, J, Yan, C. | 登録日 | 2020-02-16 | 公開日 | 2020-12-23 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis of human monocarboxylate transporter 1 inhibition by anti-cancer drug candidates. Cell, 184, 2021
|
|
5Z56
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5z56 by Molmil](/molmil-images/mine/5z56) | cryo-EM structure of a human activated spliceosome (mature Bact) at 5.1 angstrom. | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... | 著者 | Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y. | 登録日 | 2018-01-17 | 公開日 | 2018-09-19 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (5.1 Å) | 主引用文献 | Structure of the human activated spliceosome in three conformational states. Cell Res., 28, 2018
|
|
5Z58
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5z58 by Molmil](/molmil-images/mine/5z58) | Cryo-EM structure of a human activated spliceosome (early Bact) at 4.9 angstrom. | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... | 著者 | Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y. | 登録日 | 2018-01-17 | 公開日 | 2018-09-19 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | 主引用文献 | Structure of the human activated spliceosome in three conformational states. Cell Res., 28, 2018
|
|
5Z57
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5z57 by Molmil](/molmil-images/mine/5z57) | Cryo-EM structure of the human activated spliceosome (late Bact) at 6.5 angstrom | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ALANINE, BUD13 homolog, ... | 著者 | Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y. | 登録日 | 2018-01-17 | 公開日 | 2018-09-19 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | 主引用文献 | Structure of the human activated spliceosome in three conformational states. Cell Res., 28, 2018
|
|
6J6G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6j6g by Molmil](/molmil-images/mine/6j6g) | Cryo-EM structure of the yeast B*-a2 complex at an average resolution of 3.2 angstrom | 分子名称: | ACT1 pre-mRNA, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y. | 登録日 | 2019-01-15 | 公開日 | 2019-04-24 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching. Cell, 177, 2019
|
|
6J6H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6j6h by Molmil](/molmil-images/mine/6j6h) | Cryo-EM structure of the yeast B*-a1 complex at an average resolution of 3.6 angstrom | 分子名称: | ACT1 pre-mRNA, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y. | 登録日 | 2019-01-15 | 公開日 | 2019-04-24 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching. Cell, 177, 2019
|
|
6J6Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6j6q by Molmil](/molmil-images/mine/6j6q) | Cryo-EM structure of the yeast B*-b2 complex at an average resolution of 3.7 angstrom | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | 著者 | Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y. | 登録日 | 2019-01-15 | 公開日 | 2019-04-24 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching. Cell, 177, 2019
|
|
6ID1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6id1 by Molmil](/molmil-images/mine/6id1) | Cryo-EM structure of a human intron lariat spliceosome after Prp43 loaded (ILS2 complex) at 2.9 angstrom resolution | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, CWF19-like protein 2, Cell division cycle 5-like protein, ... | 著者 | Zhang, X, Zhan, X, Yan, C, Shi, Y. | 登録日 | 2018-09-07 | 公開日 | 2019-03-13 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | 主引用文献 | Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
|
|
5Y88
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5y88 by Molmil](/molmil-images/mine/5y88) | Cryo-EM structure of the intron-lariat spliceosome ready for disassembly from S.cerevisiae at 3.5 angstrom | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Intron lariat, ... | 著者 | Wan, R, Yan, C, Bai, R, Lei, J, Shi, Y. | 登録日 | 2017-08-20 | 公開日 | 2018-08-01 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | 主引用文献 | Structure of an Intron Lariat Spliceosome from Saccharomyces cerevisiae Cell(Cambridge,Mass.), 171, 2017
|
|
6ICZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6icz by Molmil](/molmil-images/mine/6icz) | Cryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 angstrom | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | 著者 | Zhang, X, Zhan, X, Yan, C, Shi, Y. | 登録日 | 2018-09-07 | 公開日 | 2019-03-13 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
|
|
6ID0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6id0 by Molmil](/molmil-images/mine/6id0) | Cryo-EM structure of a human intron lariat spliceosome prior to Prp43 loaded (ILS1 complex) at 2.9 angstrom resolution | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, CWF19-like protein 2, Cell division cycle 5-like protein, ... | 著者 | Zhang, X, Zhan, X, Yan, C, Shi, Y. | 登録日 | 2018-09-07 | 公開日 | 2019-03-13 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
|
|