8WQH
| cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 2) | 分子名称: | Coiled-coil domain-containing protein 89, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | 著者 | Chen, X, Zhang, K, Xu, C. | 登録日 | 2023-10-11 | 公開日 | 2024-04-03 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | 主引用文献 | Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase. Nat Commun, 15, 2024
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8WQI
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8WQD
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8WQG
| cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 1) | 分子名称: | Cullin-2, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ... | 著者 | Chen, X, Zhang, K, Xu, C. | 登録日 | 2023-10-11 | 公開日 | 2024-04-03 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (4.09 Å) | 主引用文献 | Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase. Nat Commun, 15, 2024
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6TQK
| Cryo-EM of native human uromodulin (UMOD)/Tamm-Horsfall protein (THP) filament. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Uromodulin, ... | 著者 | Stsiapanava, A, Xu, C, Carroni, M, Wu, B, Jovine, L. | 登録日 | 2019-12-16 | 公開日 | 2020-11-04 | 最終更新日 | 2021-03-03 | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | 主引用文献 | Cryo-EM structure of native human uromodulin, a zona pellucida module polymer. Embo J., 39, 2020
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6TQL
| Cryo-EM of elastase-treated human uromodulin (UMOD)/Tamm-Horsfall protein (THP) filament | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Stsiapanava, A, Xu, C, Carroni, M, Wu, B, Jovine, L. | 登録日 | 2019-12-16 | 公開日 | 2020-11-04 | 最終更新日 | 2021-03-03 | 実験手法 | ELECTRON MICROSCOPY (3.96 Å) | 主引用文献 | Cryo-EM structure of native human uromodulin, a zona pellucida module polymer. Embo J., 39, 2020
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8ILY
| Crystal structure of the RRM domain of human SETD1A | 分子名称: | SET domain containing 1A, histone lysine methyltransferase | 著者 | Bao, S, Xu, C. | 登録日 | 2023-03-05 | 公開日 | 2023-04-26 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Molecular insight into the SETD1A/B N-terminal region and its interaction with WDR82. Biochem.Biophys.Res.Commun., 658, 2023
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8ILZ
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8I3G
| Crystal structure of Eaf3-Eaf7 complex | 分子名称: | Chromatin modification-related protein EAF3, Chromatin modification-related protein EAF7 | 著者 | Chen, Z, Xu, C. | 登録日 | 2023-01-17 | 公開日 | 2023-05-31 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Molecular basis for Eaf3-mediated assembly of Rpd3S and NuA4. Cell Discov, 9, 2023
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8I3F
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8GXP
| Complex structure of RORgama with betulinic acid | 分子名称: | Betulinic acid, Nuclear receptor ROR-gamma | 著者 | Zhang, X.L, Xu, C, Bai, F. | 登録日 | 2022-09-20 | 公開日 | 2023-06-07 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Discovery, structural optimization, and anti-tumor bioactivity evaluations of betulinic acid derivatives as a new type of ROR gamma antagonists. Eur.J.Med.Chem., 257, 2023
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6LE6
| Structure of LNLPTQGRAR bound FEM1C | 分子名称: | Protein fem-1 homolog C,10-mer peptide, SULFATE ION | 著者 | Chen, X, Liao, S, Xu, C. | 登録日 | 2019-11-24 | 公開日 | 2020-10-21 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase. Nat.Chem.Biol., 17, 2021
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6LBF
| Crystal structure of FEM1B | 分子名称: | Protein fem-1 homolog B, SULFATE ION | 著者 | Chen, X, Liao, S, Xu, C. | 登録日 | 2019-11-14 | 公開日 | 2020-10-21 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (3.252 Å) | 主引用文献 | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase. Nat.Chem.Biol., 17, 2021
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6LDP
| Structure of CDK5R1-bound FEM1C | 分子名称: | Protein fem-1 homolog C,Peptide from Cyclin-dependent kinase 5 activator 1, SULFATE ION | 著者 | Chen, X, Liao, S, Xu, C. | 登録日 | 2019-11-22 | 公開日 | 2020-10-21 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase. Nat.Chem.Biol., 17, 2021
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6LEN
| Structure of NS11 bound FEM1C | 分子名称: | Protein fem-1 homolog C,NS11 peptide | 著者 | Chen, x, Liao, S, Xu, C. | 登録日 | 2019-11-25 | 公開日 | 2020-10-21 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.383 Å) | 主引用文献 | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase. Nat.Chem.Biol., 17, 2021
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6LF0
| Structure of FEM1C | 分子名称: | Protein fem-1 homolog C, SULFATE ION | 著者 | Chen, X, Liao, S, Xu, C. | 登録日 | 2019-11-27 | 公開日 | 2020-10-21 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase. Nat.Chem.Biol., 17, 2021
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6LBN
| Structure of SIL1-bound FEM1C | 分子名称: | Protein fem-1 homolog C,Peptide from Nucleotide exchange factor SIL1 | 著者 | Chen, X, Liao, S, Xu, C. | 登録日 | 2019-11-14 | 公開日 | 2020-10-21 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.899 Å) | 主引用文献 | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase. Nat.Chem.Biol., 17, 2021
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6LEY
| Structure of Sil1G bound FEM1C | 分子名称: | Protein fem-1 homolog C,Peptide from Nucleotide exchange factor SIL1 | 著者 | Chen, X, Liao, S, Xu, C. | 登録日 | 2019-11-27 | 公開日 | 2020-10-21 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase. Nat.Chem.Biol., 17, 2021
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4YVD
| Crytsal structure of human Pleiotropic Regulator 1 (PRL1) | 分子名称: | CHLORIDE ION, Pleiotropic regulator 1, SODIUM ION, ... | 著者 | Dong, A, Zeng, H, Xu, C, Tempel, W, Li, Y, He, H, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Min, J, Wu, H, Structural Genomics Consortium (SGC) | 登録日 | 2015-03-19 | 公開日 | 2015-04-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crytsal structure of human Pleiotropic Regulator 1 (PRL1). to be published
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5KDG
| Crystal Structure of Salmonella Typhimurium Effector GtgE | 分子名称: | GLYCEROL, Gifsy-2 prophage protein, SULFATE ION | 著者 | Kozlov, G, Xu, C, Wong, K, Gehring, K, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | 登録日 | 2016-06-08 | 公開日 | 2016-11-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Crystal Structure of the Salmonella Typhimurium Effector GtgE. PLoS ONE, 11, 2016
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4UOS
| Thermodynamic hyperstability in parametrically designed helical bundles | 分子名称: | DESIGNED HELICAL BUNDLE | 著者 | Oberdorfer, G, Huang, P, Pei, X.Y, Xu, C, Gonen, T, Nannenga, B, DiMaio, D, Rogers, J, Luisi, B.F, Baker, D. | 登録日 | 2014-06-09 | 公開日 | 2014-11-05 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | High Thermodynamic Stability of Parametrically Designed Helical Bundles Science, 346, 2014
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4UOT
| Thermodynamic hyperstability in parametrically designed helical bundles | 分子名称: | DESIGNED HELICAL BUNDLE 5H2L | 著者 | Oberdorfer, G, Huang, P, Pei, X.Y, Xu, C, Gonen, T, Nannenga, B, DiMaio, D, Rogers, J, Luisi, B.F, Baker, D. | 登録日 | 2014-06-09 | 公開日 | 2014-11-05 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | High Thermodynamic Stability of Parametrically Designed Helical Bundles Science, 346, 2014
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6T64
| A model of the EIAV CA-SP hexamer (C6) from Gag-deltaMA spheres assembled at pH6 | 分子名称: | Gag polyprotein | 著者 | Dick, R.A, Xu, C, Morado, D.R, Kravchuk, V, Ricana, C.L, Lyddon, T.D, Broad, A.M, Feathers, J.R, Johnson, M.C, Vogt, V.M, Perilla, J.R, Briggs, J.A.G, Schur, F.K.M. | 登録日 | 2019-10-17 | 公開日 | 2020-01-15 | 最終更新日 | 2022-03-30 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly. Plos Pathog., 16, 2020
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3V2X
| Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human ANKRA2 | 分子名称: | Ankyrin repeat family A protein 2, Low-density lipoprotein receptor-related protein 2 | 著者 | Lam, R, Xu, C, Bian, C.B, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2011-12-12 | 公開日 | 2012-04-04 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock. Sci.Signal., 5, 2012
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6WL8
| Cryo-EM of Form 2 peptide filament | 分子名称: | Form 2 peptide | 著者 | Wang, F, Gnewou, O.M, Xu, C, Su, Z, Egelman, E.H, Conticello, V.P. | 登録日 | 2020-04-18 | 公開日 | 2020-12-02 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials. Nat Commun, 12, 2021
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