8WQH
| cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 2) | Descriptor: | Coiled-coil domain-containing protein 89, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | Authors: | Chen, X, Zhang, K, Xu, C. | Deposit date: | 2023-10-11 | Release date: | 2024-04-03 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.44 Å) | Cite: | Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase. Nat Commun, 15, 2024
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8ILZ
| Crystal structure of the RRM domain of human SETD1B | Descriptor: | Histone-lysine N-methyltransferase SETD1B | Authors: | Bao, S, Xu, C. | Deposit date: | 2023-03-05 | Release date: | 2023-04-26 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Molecular insight into the SETD1A/B N-terminal region and its interaction with WDR82. Biochem.Biophys.Res.Commun., 658, 2023
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8ILY
| Crystal structure of the RRM domain of human SETD1A | Descriptor: | SET domain containing 1A, histone lysine methyltransferase | Authors: | Bao, S, Xu, C. | Deposit date: | 2023-03-05 | Release date: | 2023-04-26 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Molecular insight into the SETD1A/B N-terminal region and its interaction with WDR82. Biochem.Biophys.Res.Commun., 658, 2023
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8JAR
| Structure of CRL2APPBP2 bound with RxxGPAA degron (dimer) | Descriptor: | Amyloid protein-binding protein 2, Cullin-2, Elongin-B, ... | Authors: | Zhao, S, Zhang, K, Xu, C. | Deposit date: | 2023-05-07 | Release date: | 2023-10-18 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase. Proc.Natl.Acad.Sci.USA, 120, 2023
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8JAL
| Structure of CRL2APPBP2 bound with RxxGP degron (dimer) | Descriptor: | Amyloid protein-binding protein 2, Cullin-2, Elongin-B, ... | Authors: | Zhao, S, Zhang, K, Xu, C. | Deposit date: | 2023-05-06 | Release date: | 2023-10-18 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase. Proc.Natl.Acad.Sci.USA, 120, 2023
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8JAS
| Structure of CRL2APPBP2 bound with RxxGPAA degron (tetramer) | Descriptor: | Amyloid protein-binding protein 2, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | Authors: | Zhao, S, Zhang, K, Xu, C. | Deposit date: | 2023-05-07 | Release date: | 2023-10-18 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase. Proc.Natl.Acad.Sci.USA, 120, 2023
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8JAQ
| Structure of CRL2APPBP2 bound with RxxGP degron (tetramer) | Descriptor: | Amyloid protein-binding protein 2, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | Authors: | Zhao, S, Zhang, K, Xu, C. | Deposit date: | 2023-05-06 | Release date: | 2023-10-18 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase. Proc.Natl.Acad.Sci.USA, 120, 2023
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8JAU
| Structure of CRL2APPBP2 bound with the C-degron of MRPL28 (dimer) | Descriptor: | Amyloid protein-binding protein 2, Cullin-2, Elongin-B, ... | Authors: | Zhao, S, Zhang, K, Xu, C. | Deposit date: | 2023-05-07 | Release date: | 2023-10-18 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (3.22 Å) | Cite: | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase. Proc.Natl.Acad.Sci.USA, 120, 2023
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8JAV
| Structure of CRL2APPBP2 bound with the C-degron of MRPL28 (tetramer) | Descriptor: | Amyloid protein-binding protein 2, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | Authors: | Zhao, S, Zhang, K, Xu, C. | Deposit date: | 2023-05-07 | Release date: | 2023-10-18 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (3.44 Å) | Cite: | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase. Proc.Natl.Acad.Sci.USA, 120, 2023
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8J8I
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8I3G
| Crystal structure of Eaf3-Eaf7 complex | Descriptor: | Chromatin modification-related protein EAF3, Chromatin modification-related protein EAF7 | Authors: | Chen, Z, Xu, C. | Deposit date: | 2023-01-17 | Release date: | 2023-05-31 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular basis for Eaf3-mediated assembly of Rpd3S and NuA4. Cell Discov, 9, 2023
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8I3F
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6K8J
| Structure of NLRC4 CARD filament | Descriptor: | NLR family CARD domain-containing protein 4 | Authors: | Gong, Q, Xu, C, Zhang, J, Boo, Z.Z, Wu, B. | Deposit date: | 2019-06-12 | Release date: | 2020-09-16 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis for distinct inflammasome complex assembly by human NLRP1 and CARD8. Nat Commun, 12, 2021
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6LBG
| Structure of OR51B2 bound FEM1C | Descriptor: | Protein fem-1 homolog C,Peptide from Olfactory receptor 51B2, SULFATE ION | Authors: | Chen, X, Liao, S, Xu, C. | Deposit date: | 2019-11-14 | Release date: | 2020-10-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase. Nat.Chem.Biol., 17, 2021
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6LE6
| Structure of LNLPTQGRAR bound FEM1C | Descriptor: | Protein fem-1 homolog C,10-mer peptide, SULFATE ION | Authors: | Chen, X, Liao, S, Xu, C. | Deposit date: | 2019-11-24 | Release date: | 2020-10-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase. Nat.Chem.Biol., 17, 2021
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6LBF
| Crystal structure of FEM1B | Descriptor: | Protein fem-1 homolog B, SULFATE ION | Authors: | Chen, X, Liao, S, Xu, C. | Deposit date: | 2019-11-14 | Release date: | 2020-10-21 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (3.252 Å) | Cite: | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase. Nat.Chem.Biol., 17, 2021
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6LDP
| Structure of CDK5R1-bound FEM1C | Descriptor: | Protein fem-1 homolog C,Peptide from Cyclin-dependent kinase 5 activator 1, SULFATE ION | Authors: | Chen, X, Liao, S, Xu, C. | Deposit date: | 2019-11-22 | Release date: | 2020-10-21 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase. Nat.Chem.Biol., 17, 2021
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6LEN
| Structure of NS11 bound FEM1C | Descriptor: | Protein fem-1 homolog C,NS11 peptide | Authors: | Chen, x, Liao, S, Xu, C. | Deposit date: | 2019-11-25 | Release date: | 2020-10-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.383 Å) | Cite: | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase. Nat.Chem.Biol., 17, 2021
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6LBN
| Structure of SIL1-bound FEM1C | Descriptor: | Protein fem-1 homolog C,Peptide from Nucleotide exchange factor SIL1 | Authors: | Chen, X, Liao, S, Xu, C. | Deposit date: | 2019-11-14 | Release date: | 2020-10-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.899 Å) | Cite: | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase. Nat.Chem.Biol., 17, 2021
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6LEY
| Structure of Sil1G bound FEM1C | Descriptor: | Protein fem-1 homolog C,Peptide from Nucleotide exchange factor SIL1 | Authors: | Chen, X, Liao, S, Xu, C. | Deposit date: | 2019-11-27 | Release date: | 2020-10-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase. Nat.Chem.Biol., 17, 2021
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6LF0
| Structure of FEM1C | Descriptor: | Protein fem-1 homolog C, SULFATE ION | Authors: | Chen, X, Liao, S, Xu, C. | Deposit date: | 2019-11-27 | Release date: | 2020-10-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase. Nat.Chem.Biol., 17, 2021
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6MCP
| L. pneumophila effector kinase LegK7 (AMP-PNP bound) in complex with human MOB1A | Descriptor: | DI(HYDROXYETHYL)ETHER, HEXAETHYLENE GLYCOL, LegK7, ... | Authors: | Beyrakhova, K.A, Xu, C, Boniecki, M.T, Cygler, M. | Deposit date: | 2018-09-01 | Release date: | 2019-09-04 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | TheLegionellakinase LegK7 exploits the Hippo pathway scaffold protein MOB1A for allostery and substrate phosphorylation. Proc.Natl.Acad.Sci.USA, 117, 2020
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7D1L
| complex structure of two RRM domains | Descriptor: | Embryonic developmental protein tofu-6, Uncharacterized protein | Authors: | Wang, X, Liao, S, Xu, C. | Deposit date: | 2020-09-14 | Release date: | 2021-08-25 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Molecular basis for PICS-mediated piRNA biogenesis and cell division. Nat Commun, 12, 2021
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7D2Y
| complex of two RRM domains | Descriptor: | Embryonic developmental protein tofu-6, RRM2, SULFATE ION | Authors: | Wang, X, Liao, S, Xu, C. | Deposit date: | 2020-09-17 | Release date: | 2021-08-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Molecular basis for PICS-mediated piRNA biogenesis and cell division. Nat Commun, 12, 2021
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6MCQ
| L. pneumophila effector kinase LegK7 in complex with human MOB1A | Descriptor: | DI(HYDROXYETHYL)ETHER, HEXAETHYLENE GLYCOL, LegK7, ... | Authors: | Beyrakhova, K.A, Xu, C, Boniecki, M.T, Cygler, M. | Deposit date: | 2018-09-01 | Release date: | 2019-09-04 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | TheLegionellakinase LegK7 exploits the Hippo pathway scaffold protein MOB1A for allostery and substrate phosphorylation. Proc.Natl.Acad.Sci.USA, 117, 2020
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