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PDB: 157 件
5KYK
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Covalent GTP-competitive inhibitors of KRAS G12C: Guanosine bisphosphonate Analogs
分子名称: 5'-O-[(R)-[({2-[(chloroacetyl)amino]ethyl}sulfamoyl)methyl](hydroxy)phosphoryl]guanosine, GTPase KRas
著者Xiong, Y, Lu, J, Hunter, J, Li, L, Scott, D, Manandhar, A, Gondi, S, Westover, K.D, Gray, N.S.
登録日2016-07-21
公開日2017-04-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.702 Å)
主引用文献Covalent Guanosine Mimetic Inhibitors of G12C KRAS.
ACS Med Chem Lett, 8, 2017
4WHJ
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Myxovirus Resistance Protein 2 (MxB)
分子名称: Interferon-induced GTP-binding protein Mx2
著者Xiong, Y, Fribourgh, J.L, Nguyen, H.C.
登録日2014-09-22
公開日2014-10-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural Insight into HIV-1 Restriction by MxB.
Cell Host Microbe, 16, 2014
1DQF
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CRYSTAL STRUCTURE OF HELIX II OF THE X. LAEVIS SOMATIC 5S RRNA WITH A CYTOSINE BULGE IN TWO CONFORMATIONS
分子名称: CALCIUM ION, RNA (5'-R(*CP*AP*GP*GP*GP*UP*CP*GP*GP*C)-3'), RNA (5'-R(*GP*CP*CP*AP*CP*CP*CP*UP*G)-3')
著者Xiong, Y, Sundaralingam, M.
登録日2000-01-04
公開日2000-11-13
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Two crystal forms of helix II of Xenopus laevis 5S rRNA with a cytosine bulge.
RNA, 6, 2000
1DQH
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CRYSTAL STRUCTURE OF HELIX II OF THE X. LAEVIS SOMATIC 5S RRNA WITH A CYTOSINE BULGE IN TWO CONFORMATIONS
分子名称: RNA (5'-R(*CP*AP*GP*GP*GP*UP*CP*GP*GP*C)-3'), RNA (5'-R(*GP*CP*CP*AP*CP*CP*CP*UP*G)-3')
著者Xiong, Y, Sundaralingam, M.
登録日2000-01-04
公開日2000-11-13
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Two crystal forms of helix II of Xenopus laevis 5S rRNA with a cytosine bulge.
RNA, 6, 2000
2PFF
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Structural Insights of Yeast Fatty Acid Synthase
分子名称: Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, Tail protein
著者Xiong, Y, Lomakin, I.B, Steitz, T.A.
登録日2007-04-04
公開日2007-07-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structural Insights of Yeast Fatty Acid Synthase
Cell(Cambridge,Mass.), 129, 2007
3MQ7
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Crystal Structure of Ectodomain Mutant of BST-2/Tetherin/CD317
分子名称: Bone marrow stromal antigen 2, CALCIUM ION
著者Xiong, Y, Yang, H, Wang, J, Meng, W.
登録日2010-04-27
公開日2010-10-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Structural insight into the mechanisms of enveloped virus tethering by tetherin.
Proc.Natl.Acad.Sci.USA, 107, 2010
3MQ9
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Crystal Structure of Ectodomain Mutant of BST-2/Tetherin/CD317 Fused to MBP
分子名称: Bone marrow stromal antigen 2 fused to Maltose-binding periplasmic protein
著者Xiong, Y, Yang, H, Wang, J, Meng, W.
登録日2010-04-27
公開日2010-10-27
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural insight into the mechanisms of enveloped virus tethering by tetherin.
Proc.Natl.Acad.Sci.USA, 107, 2010
3MQB
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Crystal Structure of Ectodomain of BST-2/Tetherin/CD317 (C2)
分子名称: Bone marrow stromal antigen 2
著者Xiong, Y, Yang, H, Wang, J, Meng, W.
登録日2010-04-27
公開日2010-10-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural insight into the mechanisms of enveloped virus tethering by tetherin.
Proc.Natl.Acad.Sci.USA, 107, 2010
3MQC
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Crystal Structure of Ectodomain of BST-2/Tetherin/CD317 (P21)
分子名称: Bone marrow stromal antigen 2
著者Xiong, Y, Yang, H, Wang, J, Meng, W.
登録日2010-04-27
公開日2010-10-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural insight into the mechanisms of enveloped virus tethering by tetherin.
Proc.Natl.Acad.Sci.USA, 107, 2010
3G8Q
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A cytidine deaminase edits C-to-U in transfer RNAs in archaea
分子名称: Predicted RNA-binding protein, contains THUMP domain, SODIUM ION, ...
著者Xiong, Y, Stanley, B.J.
登録日2009-02-12
公開日2009-05-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A cytidine deaminase edits C to U in transfer RNAs in Archaea
Science, 324, 2009
1J9H
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Crystal Structure of an RNA Duplex with Uridine Bulges
分子名称: 5'-R(*GP*UP*GP*UP*CP*GP*(CBR)P*AP*C)-3', CALCIUM ION
著者Xiong, Y, Deng, J, Sudarsanakumar, C, Sundaralingam, M.
登録日2001-05-25
公開日2001-10-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structure of an RNA duplex r(gugucgcac)(2) with uridine bulges.
J.Mol.Biol., 313, 2001
1JZV
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Crystal structure of a bulged RNA from the SL2 stem-loop of the HIV-1 psi-RNA
分子名称: 5'-R(*CP*AP*GP*UP*AP*CP*GP*(5IC)P*C)-3', 5'-R(*GP*GP*CP*GP*AP*CP*(5BU)P*G)-3', MAGNESIUM ION
著者Xiong, Y, Sudarsanakumar, C, Deng, J, Pan, B, Sundaralingam, M.
登録日2001-09-17
公開日2003-11-11
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of a Bulged RNA from the SL2 Stem-loop of the HIV-1 psi-RNA
To be Published
1TFW
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How CCA is added to the 3' end of immature tRNA without the use of an oligonucleotide template
分子名称: 5'-R(*CP*GP*CP*GP*GP*AP*UP*CP*CP*GP*CP*AP*C)-3', 5'-R(*GP*CP*GP*GP*AP*CP*CP*CP*GP*CP*AP*C)-3', 5'-R(*GP*CP*GP*GP*AP*UP*CP*CP*GP*CP*AP*C)-3', ...
著者Xiong, Y, Steitz, T.A.
登録日2004-05-27
公開日2004-08-10
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Mechanism of transfer RNA maturation by CCA-adding enzyme without using an oligonucleotide template.
Nature, 430, 2004
1R8A
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BU of 1r8a by Molmil
Crystal Structures of an Archaeal Class I CCA-Adding Enzyme and Its Nucleotide Complexes
分子名称: MANGANESE (II) ION, SODIUM ION, tRNA nucleotidyltransferase
著者Xiong, Y, Li, F, Wang, J, Weiner, A.M, Steitz, T.A.
登録日2003-10-23
公開日2003-12-16
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of an archaeal class I CCA-adding enzyme and its nucleotide complexes
Mol.Cell, 12, 2003
1R8B
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Crystal Structures of an Archaeal Class I CCA-Adding Enzyme and Its Nucleotide
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ...
著者Xiong, Y, Li, F, Wang, J, Weiner, A.M, Steitz, T.A.
登録日2003-10-23
公開日2003-12-16
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of an archaeal class I CCA-adding enzyme and its nucleotide complexes
Mol.Cell, 12, 2003
1SZ1
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BU of 1sz1 by Molmil
Mechanism of CCA-adding enzymes specificity revealed by crystal structures of ternary complexes
分子名称: T-RNA (76-MER), tRNA nucleotidyltransferase
著者Xiong, Y, Steitz, T.A.
登録日2004-04-02
公開日2004-08-10
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (6.21 Å)
主引用文献Mechanism of transfer RNA maturation by CCA-adding enzyme without using an oligonucleotide template.
Nature, 430, 2004
1R89
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Crystal Structures of an Archaeal Class I CCA-Adding Enzyme and Its Nucleotide Complexes
分子名称: CHLORIDE ION, CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Xiong, Y, Li, F, Wang, J, Weiner, A.M, Steitz, T.A.
登録日2003-10-23
公開日2003-12-16
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structures of an archaeal class I CCA-adding enzyme and its nucleotide complexes
Mol.Cell, 12, 2003
1R8C
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BU of 1r8c by Molmil
Crystal Structures of an Archaeal Class I CCA-Adding Enzyme and Its Nucleotide
分子名称: MANGANESE (II) ION, SODIUM ION, URIDINE 5'-TRIPHOSPHATE, ...
著者Xiong, Y, Li, F, Wang, J, Weiner, A.M, Steitz, T.A.
登録日2003-10-23
公開日2003-12-16
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures of an archaeal class I CCA-adding enzyme and its nucleotide complexes
Mol.Cell, 12, 2003
1TFY
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How CCA is added to the 3' end of immature tRNA without the use of an oligonucleotide template
分子名称: 5'-R(*CP*GP*CP*GP*GP*AP*UP*C)-3', 5'-R(*CP*GP*GP*AP*UP*CP*CP*GP*CP*AP*C)-3', 5'-R(*GP*CP*GP*GP*AP*UP*AP*UP*CP*CP*GP*CP*AP*C)-3', ...
著者Xiong, Y, Steitz, T.A.
登録日2004-05-27
公開日2004-08-10
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Mechanism of transfer RNA maturation by CCA-adding enzyme without using an oligonucleotide template.
Nature, 430, 2004
421D
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5'-D(*TP*TP*CP*TP*TP*(BRO)CP*TP*TP*C)-3', 5'-R(*GP*AP*AP*GP*AP*AP*GP*AP*A)-3'
分子名称: DNA (5'-D(*TP*TP*CP*TP*TP*(CBR)P*TP*TP*C)-3'), RNA (5'-R(*GP*AP*AP*GP*AP*AP*GP*AP*A)-3')
著者Xiong, Y, Sundaralingam, M.
登録日1998-08-16
公開日1999-01-05
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure and conformation of a DNA-RNA hybrid duplex with a polypurine RNA strand: d(TTCTTBr5CTTC)-r(GAAGAAGAA).
Structure, 6, 1998
479D
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CRYSTAL STRUCTURE A DNA:RNA HYBRID DUPLEX, A DYNAMIC MODEL FOR RNASE H RECOGNITION
分子名称: DNA (5'-D(*CP*TP*CP*TP*TP*CP*TP*TP*C)-3'), RNA (5'-R(*GP*AP*AP*GP*AP*AP*GP*AP*G)-3')
著者Xiong, Y, Sundaralingam, M.
登録日1999-07-08
公開日2000-05-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of a DNA.RNA hybrid duplex with a polypurine RNA r(gaagaagag) and a complementary polypyrimidine DNA d(CTCTTCTTC).
Nucleic Acids Res., 28, 2000
8DZI
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Structure of SARS-CoV-2 Omicron BA.1.1.529 Spike trimer with one RBD down in complex with the Fab fragment of human neutralizing antibody MB.02
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Hu, Y, Xiong, Y.
登録日2022-08-07
公開日2022-08-31
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Function and Cryo-EM structures of broadly potent bispecific antibodies against multiple SARS-CoV-2 Omicron sublineages.
Signal Transduct Target Ther, 8, 2023
8DZH
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Structure of SARS-CoV-2 Omicron BA.1.1.529 Spike trimer with two RBDs down in complex with the Fab fragment of human neutralizing antibody MB.02
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Hu, Y, Xiong, Y.
登録日2022-08-07
公開日2022-08-31
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Function and Cryo-EM structures of broadly potent bispecific antibodies against multiple SARS-CoV-2 Omicron sublineages.
Signal Transduct Target Ther, 8, 2023
3DCG
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BU of 3dcg by Molmil
Crystal Structure of the HIV Vif BC-box in Complex with Human ElonginB and ElonginC
分子名称: Transcription elongation factor B polypeptide 1, Transcription elongation factor B polypeptide 2, Virion infectivity factor
著者Stanley, B.J, Ehrlich, E.S, Short, L, Yu, Y, Xiao, Z, Yu, X.-F, Xiong, Y.
登録日2008-06-03
公開日2008-07-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural insight into the human immunodeficiency virus Vif SOCS box and its role in human E3 ubiquitin ligase assembly
J.Virol., 82, 2008
7LUG
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Crystal structure of the pnRFP B30Y mutant
分子名称: PHOSPHATE ION, Red Fluorescent pnRFP B30Y mutant
著者Huang, M, Ng, H.L, Pang, Y, Zhang, S, Fan, Y, Yeh, H, Xiong, Y, Li, X, Ai, H.
登録日2021-02-22
公開日2022-03-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Development, Characterization, and Structural Analysis of a Genetically Encoded Red Fluorescent Peroxynitrite Biosensor
To Be Published

226707

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