7JUA
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7JTJ
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8GV3
| The cryo-EM structure of GSNOR with NYY001 | 分子名称: | (4P)-4-{2-[4-(1H-imidazol-1-yl)phenyl]-5-[3-oxo-3-(2-oxo-1,3-thiazolidin-3-yl)propyl]-1H-pyrrol-1-yl}-3-methylbenzamide, Alcohol dehydrogenase class-3, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Xia, Y, Zhang, Q, Yao, D, Zhao, S, Xie, L, Ji, Y, Cao, Y. | 登録日 | 2022-09-14 | 公開日 | 2023-09-20 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | The cryo-EM structure of GSNOR with NYY001 To Be Published
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1LKN
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7F3N
| Structure of PopP2 in apo form | 分子名称: | Type III effector protein popp2 | 著者 | Xia, Y, Zhang, Z.M. | 登録日 | 2021-06-16 | 公開日 | 2021-11-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.351856 Å) | 主引用文献 | Secondary-structure switch regulates the substrate binding of a YopJ family acetyltransferase. Nat Commun, 12, 2021
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7F32
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7YFK
| The structure of human pregnane X receptor in complex with an SRC-1 coactivator peptide and a limonoid compound, nomilin | 分子名称: | Nomilin, Nuclear receptor subfamily 1 group I member 2,Nuclear receptor coactivator 1 | 著者 | Xia, Y, Yao, D, Huang, C, Cao, Y. | 登録日 | 2022-07-08 | 公開日 | 2023-06-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions. Nat Commun, 14, 2023
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3CSQ
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3CT0
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7JVB
| Crystal structure of the SARS-CoV-2 spike receptor-binding domain (RBD) with nanobody Nb20 | 分子名称: | CACODYLATE ION, Nanobody Nb20, Spike protein S1 | 著者 | Xiang, Y, Xiao, Z, Liu, H, Sang, Z, Schneidman-Duhovny, D, Zhang, C, Shi, Y. | 登録日 | 2020-08-20 | 公開日 | 2020-12-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.287 Å) | 主引用文献 | Versatile and multivalent nanobodies efficiently neutralize SARS-CoV-2. Science, 370, 2020
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1P9G
| Crystal structure of a novel antifungal protein distinct with five disulfide bridges from Ecommia ulmoides Oliver at atomic resolution | 分子名称: | ACETATE ION, EAFP 2 | 著者 | Xiang, Y, Huang, R.H, Liu, X.Z, Wang, D.C. | 登録日 | 2003-05-12 | 公開日 | 2004-06-01 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (0.84 Å) | 主引用文献 | Crystal structure of a novel antifungal protein distinct with five disulfide bridges from Eucommia ulmoides Oliver at an atomic resolution. J.Struct.Biol., 148, 2004
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6A5B
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8TGO
| Crystal structure of the BG505 triple tandem trimer gp140 HIV-1 Env in complex with PGT124 and 35O22 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 scFv, ... | 著者 | Xian, Y, Yuan, M, Wilson, I.A. | 登録日 | 2023-07-12 | 公開日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (5.75 Å) | 主引用文献 | Triple tandem trimer immunogens for HIV-1 and influenza nucleic acid-based vaccines. Npj Vaccines, 9, 2024
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8IP0
| Cryo-EM structure of type I-B Cascade bound to a PAM-containing dsDNA target at 3.6 angstrom resolution | 分子名称: | CRISPR associated protein Cas11b, DNA (41-MER), DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), ... | 著者 | Xiao, Y, Lu, M, Yu, C, Zhang, Y. | 登録日 | 2023-03-13 | 公開日 | 2024-03-20 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structure and genome editing of type I-B CRISPR-Cas. Nat Commun, 15, 2024
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8IKX
| An Arabidopsis polygalacturonase PGLR | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Pectin lyase-like superfamily protein, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Xiao, Y, Chai, J. | 登録日 | 2023-03-01 | 公開日 | 2024-02-07 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | A plant mechanism of hijacking pathogen virulence factors to trigger innate immunity. Science, 383, 2024
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8IKW
| A complex structure of PGIP-PG | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Endo-polygalacturonase, ... | 著者 | Xiao, Y, Chai, J. | 登録日 | 2023-03-01 | 公開日 | 2024-02-07 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | A plant mechanism of hijacking pathogen virulence factors to trigger innate immunity. Science, 383, 2024
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1T7B
| Crystal structure of mutant Lys8Gln of scorpion alpha-like neurotoxin BmK M1 from Buthus martensii Karsch | 分子名称: | Alpha-like neurotoxin BmK-I | 著者 | Xiang, Y, Guan, R.J, He, X.L, Wang, C.G, Wang, M, Zhang, Y, Sundberg, E.J, Wang, D.C. | 登録日 | 2004-05-09 | 公開日 | 2004-09-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural Mechanism Governing Cis and Trans Isomeric States and an Intramolecular Switch for Cis/Trans Isomerization of a Non-proline Peptide Bond Observed in Crystal Structures of Scorpion Toxins J.Mol.Biol., 341, 2004
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5KKB
| Structure of mouse Golgi alpha-1,2-mannosidase IA and Man9GlcNAc2-PA complex | 分子名称: | 1,4-BUTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, ... | 著者 | Xiang, Y, Moremen, K.W. | 登録日 | 2016-06-21 | 公開日 | 2016-12-07 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.774 Å) | 主引用文献 | Substrate recognition and catalysis by GH47 alpha-mannosidases involved in Asn-linked glycan maturation in the mammalian secretory pathway. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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1T7A
| Crystal structure of mutant Lys8Asp of scorpion alpha-like neurotoxin BmK M1 from Buthus martensii Karsch | 分子名称: | Alpha-like neurotoxin BmK-I | 著者 | Xiang, Y, Guan, R.J, He, X.L, Wang, C.G, Wang, M, Zhang, Y, Sundberg, E.J, Wang, D.C. | 登録日 | 2004-05-08 | 公開日 | 2004-09-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural Mechanism Governing Cis and Trans Isomeric States and an Intramolecular Switch for Cis/Trans Isomerization of a Non-proline Peptide Bond Observed in Crystal Structures of Scorpion Toxins J.Mol.Biol., 341, 2004
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1T7E
| Crystal structure of mutant Pro9Ser of scorpion alpha-like neurotoxin BmK M1 from Buthus martensii Karsch | 分子名称: | Alpha-like neurotoxin BmK-I, PHOSPHATE ION | 著者 | Xiang, Y, Guan, R.J, He, X.L, Wang, C.G, Wang, M, Zhang, Y, Sundberg, E.J, Wang, D.C. | 登録日 | 2004-05-09 | 公開日 | 2004-09-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structural Mechanism Governing Cis and Trans Isomeric States and an Intramolecular Switch for Cis/Trans Isomerization of a Non-proline Peptide Bond Observed in Crystal Structures of Scorpion Toxins J.Mol.Biol., 341, 2004
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2MXU
| 42-Residue Beta Amyloid Fibril | 分子名称: | Amyloid beta A4 protein | 著者 | Xiao, Y, Ma, B, McElheny, D, Parthasarathy, S, Long, F, Hoshi, M, Nussinov, R, Ishii, Y. | 登録日 | 2015-01-14 | 公開日 | 2015-05-06 | 最終更新日 | 2024-05-01 | 実験手法 | SOLID-STATE NMR | 主引用文献 | A beta (1-42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease. Nat.Struct.Mol.Biol., 22, 2015
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8H7Q
| Cryo-EM structure of Synechocystis sp. PCC6714 Cascade at 3.8 angstrom resolution | 分子名称: | CRISPR RNA, CRISPR associated protein Cas11b, CRISPR associated protein Cas5, ... | 著者 | Xiao, Y, Lu, M, Yu, C, Zhang, Y. | 登録日 | 2022-10-20 | 公開日 | 2023-10-25 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Cryo-EM structure of Synechocystis sp. PCC6714 Cascade at 3.8 angstrom resolution To Be Published
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8H67
| type I-B Cascade bound to a PAM-containing dsDNA target at 3.8 angstrom resolution. | 分子名称: | CRISPR RNA, CRISPR associated protein Cas11b, CRISPR associated protein Cas5, ... | 著者 | Xiao, Y, Lu, M, Yu, C, Zhang, Y. | 登録日 | 2022-10-15 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure and genome editing of type I-B CRISPR-Cas. Nat Commun, 15, 2024
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8D6J
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8D71
| Human Ago2 bound to miR122(21nt) | 分子名称: | MAGNESIUM ION, Protein argonaute-2, miR-122-21nt | 著者 | Xiao, Y, MacRae, I. | 登録日 | 2022-06-07 | 公開日 | 2023-05-03 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A tiny loop in the Argonaute PIWI domain tunes small RNA seed strength. Embo Rep., 24, 2023
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