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PDB: 10 件
4M4Z
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SH3 and SH2 domains of human Src-like adaptor protein 2 (SLAP2)
分子名称: Src-like-adapter 2
著者Wybenga-Groot, L.E, McGlade, C.J.
登録日2013-08-07
公開日2013-11-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of Src-like adaptor protein 2 reveals close association of SH3 and SH2 domains through beta-sheet formation.
Cell Signal, 25, 2013
1B87
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BU of 1b87 by Molmil
CRYSTAL STRUCTURE OF AN AMINOGLYCOSIDE 6'-N-ACETYLTRANSFERASE
分子名称: ACETYL COENZYME *A, PROTEIN (AMINOGLYCOSIDE N6'-ACETYLTRANSFERASE TYPE 1)
著者Wybenga-Groot, L.E, Berghuis, A.M.
登録日1999-02-09
公開日1999-06-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of an aminoglycoside 6'-N-acetyltransferase: defining the GCN5-related N-acetyltransferase superfamily fold.
Structure Fold.Des., 7, 1999
6XAR
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Structure of CBL tyrosine kinase binding domain (TKBD) with C-terminal tail of Src-like kinase protein 2 (SLAP2)
分子名称: CALCIUM ION, E3 ubiquitin-protein ligase CBL, Src-like-adapter 2
著者Wybenga-Groot, L.E, McGlade, C.J.
登録日2020-06-04
公開日2021-03-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献SLAP2 Adaptor Binding Disrupts c-CBL Autoinhibition to Activate Ubiquitin Ligase Function.
J.Mol.Biol., 433, 2021
4TZI
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Structure of unliganded Lyn SH2 domain
分子名称: Tyrosine-protein kinase Lyn
著者Wybenga-Groot, L.E.
登録日2014-07-10
公開日2015-01-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Tyrosine Phosphorylation of the Lyn Src Homology 2 (SH2) Domain Modulates Its Binding Affinity and Specificity.
Mol.Cell Proteomics, 14, 2015
4PDP
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Crystal structure of Rad53 kinase domain and SCD2
分子名称: Serine/threonine-protein kinase RAD53
著者Wybenga-Groot, L.E, Ho, C.S, Ceccarelli, D.F, Sicheri, F.
登録日2014-04-19
公開日2014-05-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.591 Å)
主引用文献Structural basis of Rad53 kinase activation by dimerization and activation segment exchange.
Cell Signal., 26, 2014
1JPA
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Crystal Structure of unphosphorylated EphB2 receptor tyrosine kinase and juxtamembrane region
分子名称: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, neural kinase, Nuk=Eph/Elk/Eck family receptor-like tyrosine kinase
著者Wybenga-Groot, L.E, Pawson, T, Sicheri, F.
登録日2001-08-01
公開日2001-10-03
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region.
Cell(Cambridge,Mass.), 106, 2001
2HEL
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BU of 2hel by Molmil
Crystal structure of a mutant EphA4 kinase domain (Y742A)
分子名称: Eph receptor A4
著者Wybenga-Groot, L.E, Sicheri, F, Pawson, T.
登録日2006-06-21
公開日2007-02-13
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献A change in conformational dynamics underlies the activation of Eph receptor tyrosine kinases.
EMBO J., 25, 2006
2HEN
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Crystal Structure of the EphB2 Receptor Kinase domain in complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Ephrin type-B receptor 2, MAGNESIUM ION
著者Wybenga-Groot, L.E, Sicheri, F, Pawson, T.
登録日2006-06-21
公開日2007-02-13
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A change in conformational dynamics underlies the activation of Eph receptor tyrosine kinases
EMBO J., 25, 2006
1N71
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Crystal structure of aminoglycoside 6'-acetyltransferase type Ii in complex with coenzyme A
分子名称: COENZYME A, SULFATE ION, aac(6')-Ii
著者Burk, D.L, Ghuman, N, Wybenga-Groot, L.E, Berghuis, A.M.
登録日2002-11-12
公開日2003-03-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献X-ray structure of the AAC(6')-Ii antibiotic resistance enzyme at 1.8 A resolution; examination of oligomeric arrangements in GNAT superfamily members
Protein Sci., 12, 2003
4PDS
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Crystal structure of Rad53 kinase domain and SCD2 in complex with AMPPNP
分子名称: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase RAD53
著者Ho, C.S, Wybenga-Groot, L.E, Ceccarelli, D.F, Sicheri, F.
登録日2014-04-21
公開日2014-05-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis of Rad53 kinase activation by dimerization and activation segment exchange.
Cell Signal., 26, 2014

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