6UI7
 
 | | HBV T=4 149C3A | | 分子名称: | Core protein | | 著者 | Wu, W, Watts, N.R, Cheng, N, Huang, R, Steven, A, Wingfield, P.T. | | 登録日 | 2019-09-30 | | 公開日 | 2019-11-06 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | | 主引用文献 | Expression of quasi-equivalence and capsid dimorphism in the Hepadnaviridae.
Plos Comput.Biol., 16, 2020
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2M2U
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2M2W
 | | Ternary complex of ASFV Pol X with DNA and MgdGTP | | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(P*GP*GP*CP*GP*AP*AP*GP*CP*CP*GP*GP*GP*TP*GP*CP*GP*AP*AP*GP*CP*AP*CP*(DOC))-3', MAGNESIUM ION, ... | | 著者 | Wu, W, Su, M, Tsai, M. | | 登録日 | 2013-01-03 | | 公開日 | 2014-04-02 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | How a low-fidelity DNA polymerase chooses non-Watson-Crick from Watson-Crick incorporation.
J.Am.Chem.Soc., 136, 2014
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2M2T
 | | ASFV Pol X structure | | 分子名称: | Repair DNA polymerase X | | 著者 | Wu, W, Su, M, Tsai, M. | | 登録日 | 2013-01-03 | | 公開日 | 2014-04-02 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | How a low-fidelity DNA polymerase chooses non-Watson-Crick from Watson-Crick incorporation.
J.Am.Chem.Soc., 136, 2014
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2M2V
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6UI6
 | | HBV T=3 149C3A | | 分子名称: | Core protein | | 著者 | Wu, W, Watts, N.R, Cheng, N, Huang, R, Steven, A, Wingfield, P.T. | | 登録日 | 2019-09-30 | | 公開日 | 2019-11-06 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | | 主引用文献 | Expression of quasi-equivalence and capsid dimorphism in the Hepadnaviridae.
Plos Comput.Biol., 16, 2020
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4EKL
 | | Akt1 with GDC0068 | | 分子名称: | (2S)-2-(4-chlorophenyl)-1-{4-[(5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]piperazin-1-yl}-3-(propan-2-ylamino)propan-1-one, RAC-alpha serine/threonine-protein kinase | | 著者 | Wu, W.-I, Vigers, G.P.A, Morales, T.H, Brandhuber, B.J. | | 登録日 | 2012-04-09 | | 公開日 | 2012-05-23 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | An ATP-Site On-Off Switch That Restricts Phosphatase Accessibility of Akt.
Sci.Signal., 5, 2012
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4EKK
 | | Akt1 with AMP-PNP | | 分子名称: | Glycogen synthase kinase-3 beta, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Wu, W.-I, Vigers, G.P.A, Morales, T.H, Brandhuber, B.J. | | 登録日 | 2012-04-09 | | 公開日 | 2012-05-23 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | An ATP-Site On-Off Switch That Restricts Phosphatase Accessibility of Akt.
Sci.Signal., 5, 2012
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6LB8
 | | Crystal structure of the Ca2+-free T4L-MICU1-MICU2 complex | | 分子名称: | Calcium uptake protein 2, mitochondrial, Endolysin,Calcium uptake protein 1 | | 著者 | Wu, W, Shen, Q, Zheng, J, Jia, Z. | | 登録日 | 2019-11-13 | | 公開日 | 2020-07-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.283 Å) | | 主引用文献 | The structure of the MICU1-MICU2 complex unveils the regulation of the mitochondrial calcium uniporter.
Embo J., 39, 2020
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6LB7
 | | Crystal structure of the Ca2+-free and Ca2+-bound MICU1-MICU2 complex | | 分子名称: | CALCIUM ION, Calcium uptake protein 1, mitochondrial, ... | | 著者 | Wu, W, Shen, Q, Zheng, J, Jia, Z. | | 登録日 | 2019-11-13 | | 公開日 | 2020-07-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | | 主引用文献 | The structure of the MICU1-MICU2 complex unveils the regulation of the mitochondrial calcium uniporter.
Embo J., 39, 2020
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3Q9L
 | | The structure of the dimeric E.coli MinD-ATP complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Septum site-determining protein minD | | 著者 | Wu, W, Park, K.-T, Lutkenhaus, J, Holyoak, T. | | 登録日 | 2011-01-08 | | 公開日 | 2011-01-26 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.343 Å) | | 主引用文献 | Determination of the structure of the MinD-ATP complex reveals the orientation of MinD on the membrane and the relative location of the binding sites for MinE and MinC.
Mol.Microbiol., 79, 2011
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6INB
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6INC
 | | Crystal structure of an acetolactate decarboxylase from Klebsiella pneumoniae | | 分子名称: | 1,2-ETHANEDIOL, Alpha-acetolactate decarboxylase, CHLORIDE ION, ... | | 著者 | Wu, W, Zhang, Q, Bartlam, M. | | 登録日 | 2018-10-24 | | 公開日 | 2019-01-16 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.604 Å) | | 主引用文献 | Structural characterization of an acetolactate decarboxylase from Klebsiella pneumoniae
Biochem. Biophys. Res. Commun., 509, 2019
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6JC4
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7FJ8
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7FJ9
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7FJ7
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7FJA
 | | KpAckA (PduW) with AMPPNP, ethylene glycol complex structure | | 分子名称: | 1,2-ETHANEDIOL, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Probable propionate kinase | | 著者 | Wu, W, Zhang, Q, Bartlam, M. | | 登録日 | 2021-08-03 | | 公開日 | 2022-08-10 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | KpAckA (PduW) with AMPPNP, ethylene glycol complex structure
To Be Published
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3ZL9
 | | Crystal structure of the nucleocapsid protein from Schmallenberg virus | | 分子名称: | NUCLEOCAPSID PROTEIN | | 著者 | Ariza, A, Tanner, S.J, Walter, C.T, Dent, K.C, Shepherd, D.A, Wu, W, Matthews, S.V, Hiscox, J.A, Green, T.J, Luo, M, Elliot, R.M, Ashcroft, A.E, Stonehouse, N.J, Ranson, N.A, Barr, J.N, Edwards, T.A. | | 登録日 | 2013-01-29 | | 公開日 | 2013-05-01 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Nucleocapsid Protein Structures from Orthobunyaviruses Reveal Insight Into Ribonucleoprotein Architecture and RNA Polymerization.
Nucleic Acids Res., 41, 2013
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3ZLA
 | | Crystal structure of the nucleocapsid protein from Bunyamwera virus bound to RNA | | 分子名称: | NUCLEOPROTEIN, RNA | | 著者 | Ariza, A, Tanner, S.J, Walter, C.T, Dent, K.C, Shepherd, D.A, Wu, W, Matthews, S.V, Hiscox, J.A, Green, T.J, Luo, M, Elliot, R.M, Ashcroft, A.E, Stonehouse, N.J, Ranson, N.A, Barr, J.N, Edwards, T.A. | | 登録日 | 2013-01-29 | | 公開日 | 2013-05-01 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Nucleocapsid Protein Structures from Orthobunyaviruses Reveal Insight Into Ribonucleoprotein Architecture and RNA Polymerization.
Nucleic Acids Res., 41, 2013
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8KCM
 | | MmCPDII-DNA complex containing low-dosage, light induced repaired DNA. | | 分子名称: | Deoxyribodipyrimidine photo-lyase, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | | 著者 | Maestre-Reyna, M, Wang, P.-H, Nango, E, Hosokawa, Y, Saft, M, Furrer, A, Yang, C.-H, Ngura Putu, E.P.G, Wu, W.-J, Emmerich, H.-J, Engilberge, S, Caramello, N, Wranik, M, Glover, H.L, Franz-Badur, S, Wu, H.-Y, Lee, C.-C, Huang, W.-C, Huang, K.-F, Chang, Y.-K, Liao, J.-H, Weng, J.-H, Gad, W, Chang, C.-W, Pang, A.H, Gashi, D, Beale, E, Ozerov, D, Milne, C, Cirelli, C, Bacellar, C, Sugahara, M, Owada, S, Joti, Y, Yamashita, A, Tanaka, R, Tanaka, T, Luo, F.J, Tono, K, Kiontke, S, Spadaccini, R, Royant, A, Yamamoto, J, Iwata, S, Standfuss, J, Essen, L.-O, Bessho, Y, Tsai, M.-D. | | 登録日 | 2023-08-08 | | 公開日 | 2023-11-22 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Visualizing the DNA repair process by a photolyase at atomic resolution.
Science, 382, 2023
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9C1R
 | | Crystal structure of mutant cMET D1228N kinase domain in complex with inhibitor compound 13 | | 分子名称: | GLYCEROL, Hepatocyte growth factor receptor, N-(2,5-difluoro-4-{[(1s,3S)-3-(1-methyl-1H-pyrazol-3-yl)cyclobutyl][(8R)-pyrazolo[1,5-a]pyrazin-4-yl]amino}phenyl)-2-(5-fluoropyridin-2-yl)-3-oxo-2,3-dihydropyridazine-4-carboxamide | | 著者 | Simpson, H, Wu, W.-I, Mou, T.-C. | | 登録日 | 2024-05-29 | | 公開日 | 2024-08-21 | | 最終更新日 | 2024-09-04 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Discovery of Pyrazolopyrazines as Selective, Potent, and Mutant-Active MET Inhibitors with Intracranial Efficacy.
J.Med.Chem., 67, 2024
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9BLG
 | | Crystal structure of non-receptor protein tyrosine phosphatase SHP2 in complex with PF-07284892 | | 分子名称: | (1S)-1'-{6-[(2-amino-3-chloropyridin-4-yl)sulfanyl]-1,2,4-triazin-3-yl}-1,3-dihydrospiro[indene-2,4'-piperidin]-1-amine, Tyrosine-protein phosphatase non-receptor type 11 | | 著者 | Bester, S.M, Wu, W.-I, Mou, T.-C. | | 登録日 | 2024-04-30 | | 公開日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | SHP2 Inhibition Sensitizes Diverse Oncogene-Addicted Solid Tumors to Re-treatment with Targeted Therapy.
Cancer Discov, 13, 2023
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5N98
 | | Crystal Structure of Drosophila DHX36 helicase in complex with TAGGGTTTT | | 分子名称: | CG9323, isoform A, DNA (5'-D(P*TP*AP*GP*GP*GP*TP*TP*TP*T)-3'), ... | | 著者 | Chen, W.-F, Rety, S, Guo, H.-L, Wu, W.-Q, Liu, N.-N, Liu, Q.-W, Dai, Y.-X, Xi, X.-G. | | 登録日 | 2017-02-24 | | 公開日 | 2018-03-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.756 Å) | | 主引用文献 | Molecular Mechanistic Insights into Drosophila DHX36-Mediated G-Quadruplex Unfolding: A Structure-Based Model.
Structure, 26, 2018
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5N94
 | | Crystal Structure of Drosophila DHX36 helicase in complex with polyU | | 分子名称: | CG9323, isoform A, RNA (5'-R(P*UP*UP*UP*UP*UP*UP*UP*U)-3') | | 著者 | Chen, W.-F, Rety, S, Hai-Lei Guo, H.-L, Wu, W.-Q, Liu, N.-N, Liu, Q.-W, Dai, Y.-X, Xi, X.-G. | | 登録日 | 2017-02-24 | | 公開日 | 2018-03-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.428 Å) | | 主引用文献 | Molecular Mechanistic Insights into Drosophila DHX36-Mediated G-Quadruplex Unfolding: A Structure-Based Model.
Structure, 26, 2018
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