5D76
 
 | |
5E9C
 | | Crystal structure of human heparanase in complex with heparin tetrasaccharide dp4 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-beta-D-glucopyranose, CHLORIDE ION, ... | | 著者 | Wu, L, Davies, G.J. | | 登録日 | 2015-10-15 | | 公開日 | 2015-11-18 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Structural characterization of human heparanase reveals insights into substrate recognition.
Nat.Struct.Mol.Biol., 22, 2015
|
|
5E8M
 | | Crystal structure of human heparanase | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | 著者 | Wu, L, Davies, G.J. | | 登録日 | 2015-10-14 | | 公開日 | 2015-11-18 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural characterization of human heparanase reveals insights into substrate recognition.
Nat.Struct.Mol.Biol., 22, 2015
|
|
5E97
 | | Glycoside Hydrolase ligand structure 1 | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | 著者 | Wu, L, Davies, G.J. | | 登録日 | 2015-10-14 | | 公開日 | 2015-11-18 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Structural characterization of human heparanase reveals insights into substrate recognition.
Nat.Struct.Mol.Biol., 22, 2015
|
|
5GKW
 | | crystal structure of SZ529 complex with (R,R)-cyclopentanediol | | 分子名称: | (1~{R},2~{R})-cyclopentane-1,2-diol, Limonene-1,2-epoxide hydrolase | | 著者 | Wu, L, Sun, Z.T, Reetz, M.T, Zhou, J.H. | | 登録日 | 2016-07-07 | | 公開日 | 2017-07-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | crystal structure of SZ529 complex with (R,R)-cyclopentanediol
To Be Published
|
|
3PVL
 | | Structure of myosin VIIa MyTH4-FERM-SH3 in complex with the CEN1 of Sans | | 分子名称: | GLYCEROL, Myosin VIIa isoform 1, PHOSPHATE ION, ... | | 著者 | Wu, L, Pan, L.F, Wei, Z.Y, Zhang, M.J. | | 登録日 | 2010-12-07 | | 公開日 | 2011-03-02 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of MyTH4-FERM domains in myosin VIIa tail bound to cargo.
Science, 331, 2011
|
|
6KVW
 | |
6HZY
 | | Crystal structure of a bacterial fucosidase with inhibitor FucPUG | | 分子名称: | 1,2-ETHANEDIOL, Alpha-L-fucosidase, SULFATE ION, ... | | 著者 | Wu, L, Davies, G.J, Stubbs, K.A, Coyle, T, Debowski, A.W. | | 登録日 | 2018-10-24 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Synthetic and Crystallographic Insight into Exploiting sp2Hybridization in the Development of alpha-l-Fucosidase Inhibitors.
Chembiochem, 20, 2019
|
|
5ZOL
 | | Crystal structure of a three sites mutantion of FSAA complexed with HA and product | | 分子名称: | (3S,4S)-3,4-dihydroxy-4-(thiophen-2-yl)butan-2-one, 1-hydroxypropan-2-one, CHLORIDE ION, ... | | 著者 | Wu, L, Yang, X.H, Yu, H.W, Zhou, J.H. | | 登録日 | 2018-04-13 | | 公開日 | 2019-06-12 | | 最終更新日 | 2020-07-22 | | 実験手法 | X-RAY DIFFRACTION (2.172 Å) | | 主引用文献 | The engineering of decameric d-fructose-6-phosphate aldolase A by combinatorial modulation of inter- and intra-subunit interactions.
Chem.Commun.(Camb.), 56, 2020
|
|
8HIV
 | |
5YNG
 | | Crystal structure of SZ348 in complex with cyclopentene oxide | | 分子名称: | (1R,5S)-6-oxabicyclo[3.1.0]hexane, Limonene-1,2-epoxide hydrolase, NICKEL (II) ION, ... | | 著者 | Wu, L, Sun, Z.T, Reetz, M.T, Zhou, J.H. | | 登録日 | 2017-10-24 | | 公開日 | 2018-06-27 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.497 Å) | | 主引用文献 | Structural and Computational Insight into the Catalytic Mechanism of Limonene Epoxide Hydrolase Mutants in Stereoselective Transformations.
J. Am. Chem. Soc., 140, 2018
|
|
7V3E
 | |
7V2U
 | | The complex structure of SoBcmB and its product 2f | | 分子名称: | (1S,5S,6S)-5-methyl-1-[(1S,2S)-2-methyl-1,2,3-tris(oxidanyl)propyl]-2-oxa-7,9-diazabicyclo[4.2.2]decane-8,10-dione, 2-OXOGLUTARIC ACID, CHLORIDE ION, ... | | 著者 | Wu, L, Zhou, J.H. | | 登録日 | 2021-08-09 | | 公開日 | 2023-02-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.00009918 Å) | | 主引用文献 | The complex structure of SoBcmB and its product 2f
To Be Published
|
|
7V34
 | | The complex structure of soBcmB and its product 1d | | 分子名称: | (3S,4S,5S,8S)-8-[(2S)-butan-2-yl]-3-methyl-3,4-bis(oxidanyl)-1-oxa-7,10-diazaspiro[4.5]decane-6,9-dione, 2-OXOGLUTARIC ACID, CHLORIDE ION, ... | | 著者 | Wu, L, Zhou, J.H. | | 登録日 | 2021-08-10 | | 公開日 | 2023-02-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.000169 Å) | | 主引用文献 | The complex structure of SoBcmB and its side way product
To Be Published
|
|
7V36
 | |
7V3N
 | |
7V2X
 | | The complex structure of soBcmB and its substrate 1 | | 分子名称: | (3S,6S)-3-[(2S)-butan-2-yl]-6-[(2R)-2-methyl-2,3-bis(oxidanyl)propyl]piperazine-2,5-dion, 2-OXOGLUTARIC ACID, FE (II) ION, ... | | 著者 | Wu, L, Zhou, J.H. | | 登録日 | 2021-08-10 | | 公開日 | 2023-02-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.08387423 Å) | | 主引用文献 | The crystal structure of SoBcmB and its side way substrate
To Be Published
|
|
7V3O
 | |
6Q7I
 | | GH3 exo-beta-xylosidase (XlnD) | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Davies, G.J, Rowland, R.J, Wu, L, Moroz, O, Blagova, E. | | 登録日 | 2018-12-13 | | 公開日 | 2019-06-05 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | | 主引用文献 | Dynamic and Functional Profiling of Xylan-Degrading Enzymes inAspergillusSecretomes Using Activity-Based Probes.
Acs Cent.Sci., 5, 2019
|
|
6Q8N
 | | GH10 endo-xylanase in complex with xylobiose epoxide inhibitor | | 分子名称: | (1~{R},2~{S},4~{S},5~{R})-cyclohexane-1,2,3,4,5-pentol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Davies, G.J, Rowland, R.J, Wu, L, Moroz, O, Blagova, E. | | 登録日 | 2018-12-15 | | 公開日 | 2019-06-05 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Dynamic and Functional Profiling of Xylan-Degrading Enzymes inAspergillusSecretomes Using Activity-Based Probes.
Acs Cent.Sci., 5, 2019
|
|
6Q8M
 | | GH10 endo-xylanase | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-xylanase, ... | | 著者 | Davies, G.J, Rowland, R.J, Wu, L, Moroz, O, Blagova, E. | | 登録日 | 2018-12-15 | | 公開日 | 2019-06-05 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | | 主引用文献 | Dynamic and Functional Profiling of Xylan-Degrading Enzymes inAspergillusSecretomes Using Activity-Based Probes.
Acs Cent.Sci., 5, 2019
|
|
4OHE
 | | LEOPARD Syndrome-Associated SHP2/G464A mutant | | 分子名称: | Tyrosine-protein phosphatase non-receptor type 11 | | 著者 | Yu, Z.H, Zhang, R.Y, Walls, C.D, Chen, L, Zhang, S, Wu, L, Wang, L, Liu, S, Zhang, Z.Y. | | 登録日 | 2014-01-17 | | 公開日 | 2014-09-24 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.506 Å) | | 主引用文献 | Molecular basis of gain-of-function LEOPARD syndrome-associated SHP2 mutations.
Biochemistry, 53, 2014
|
|
4OHD
 | | LEOPARD Syndrome-Associated SHP2/A461T mutant | | 分子名称: | Tyrosine-protein phosphatase non-receptor type 11 | | 著者 | Yu, Z.H, Zhang, R.Y, Walls, C.D, Chen, L, Zhang, S, Wu, L, Wang, L, Liu, S, Zhang, Z.Y. | | 登録日 | 2014-01-17 | | 公開日 | 2014-09-24 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Molecular basis of gain-of-function LEOPARD syndrome-associated SHP2 mutations.
Biochemistry, 53, 2014
|
|
6LCV
 | |
8CHS
 | |
