8CD0

Human heparan sulfate N-deacetylase-N-sulfotransferase 1 in complex with calcium, 3'-phosphoadenosine-5'-phosphosulfate, and nanobody nAb7 (composite map and model)

Summary for 8CD0

• Entry DOI: 10.2210/pdb8cd0/pdb
• Related: 1NST 8CD0
• EMDB information: 16564 16565
• Descriptor: Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1, Nanobody nAb7, ADENOSINE-3'-5'-DIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: deacetylase, sulfotransferase, heparan sulfate, carbohydrate, glycosaminoglycan, nanobody
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 119121.21

Authors

Mycroft-West, C.J.,Wu, L. (deposition date: 2023-01-29, release date: 2024-02-07, Last modification date: 2024-02-28)

• Primary citation: Mycroft-West, C.J.,Abdelkarim, S.,Duyvesteyn, H.M.E.,Gandhi, N.S.,Skidmore, M.A.,Owens, R.J.,Wu, L.; Structural and mechanistic characterization of bifunctional heparan sulfate N-deacetylase-N-sulfotransferase 1.; Nat Commun, 15:1326-1326, 2024; PubMed: 38351061; DOI: 10.1038/s41467-024-45419-4

Experimental method

ELECTRON MICROSCOPY (2.42 Å)