8CD0
Human heparan sulfate N-deacetylase-N-sulfotransferase 1 in complex with calcium, 3'-phosphoadenosine-5'-phosphosulfate, and nanobody nAb7 (composite map and model)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000139 | cellular_component | Golgi membrane |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005794 | cellular_component | Golgi apparatus |
| A | 0006954 | biological_process | inflammatory response |
| A | 0008146 | molecular_function | sulfotransferase activity |
| A | 0015012 | biological_process | heparan sulfate proteoglycan biosynthetic process |
| A | 0015016 | molecular_function | heparan sulfate N-sulfotransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0019213 | molecular_function | deacetylase activity |
| A | 0030210 | biological_process | heparin proteoglycan biosynthetic process |
| A | 0032588 | cellular_component | trans-Golgi network membrane |
| A | 0050119 | molecular_function | N-acetylglucosamine deacetylase activity |
| A | 0102140 | molecular_function | heparan sulfate N-deacetylase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"For sulfotransferase activity","evidences":[{"source":"PubMed","id":"9744796","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10196134","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1NST","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
