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PDB: 20 results
4YNZ
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BU of 4ynz by Molmil
Structure of the N-terminal domain of SAD
Descriptor: Serine/threonine-protein kinase BRSK2
Authors:Wu, J.X, Wang, J, Chen, L, Wang, Z.X, Wu, J.W.
Deposit date:2015-03-11
Release date:2015-12-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insight into the mechanism of synergistic autoinhibition of SAD kinases
Nat Commun, 6, 2015
4YOM
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BU of 4yom by Molmil
Structure of SAD kinase
Descriptor: 1,2-ETHANEDIOL, Serine/threonine-protein kinase BRSK2
Authors:Wu, J.X, Wang, J, Chen, L, Wang, Z.X, Wu, J.W.
Deposit date:2015-03-12
Release date:2015-12-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structural insight into the mechanism of synergistic autoinhibition of SAD kinases
Nat Commun, 6, 2015
8XB4
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BU of 8xb4 by Molmil
Structure of apo state of the human Norepinephrine Transporter
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GFP-MBP-solute carrier family 6 member 2
Authors:Wu, J.X, Ji, W.M.
Deposit date:2023-12-05
Release date:2024-06-26
Last modified:2024-09-25
Method:ELECTRON MICROSCOPY (2.92 Å)
Cite:Substrate binding and inhibition mechanism of norepinephrine transporter.
Nature, 633, 2024
8XB2
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BU of 8xb2 by Molmil
Structure of radafaxine-bound state of the human Norepinephrine Transporter
Descriptor: (2~{S},3~{S})-2-(3-chlorophenyl)-3,5,5-trimethyl-morpholin-2-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, GFP-MBP-solute carrier family 6 member 2,Maltose/maltodextrin-binding periplasmic protein,Sodium-dependent noradrenaline transporter,Maltose/maltodextrin-binding periplasmic protein,Sodium-dependent noradrenaline transporter
Authors:Wu, J.X, Ji, W.M.
Deposit date:2023-12-05
Release date:2024-07-10
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Substrate binding and inhibition mechanism of norepinephrine transporter.
Nature, 633, 2024
5IRI
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BU of 5iri by Molmil
Structure of the mouse SAD-B AIS-KA1 fragment
Descriptor: Serine/threonine-protein kinase BRSK1
Authors:Ma, H, Wu, J.X, Wang, J, Wu, J.W.
Deposit date:2016-03-13
Release date:2016-06-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure and inhibition analysis of the mouse SAD-B C-terminal fragment
Biosci.Biotechnol.Biochem., 2016
8XB3
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BU of 8xb3 by Molmil
Structural mechanism of substrate binding and inhibition of the human Norepinephrine Transporter
Descriptor: 1-[(3-iodanylphenyl)methyl]guanidine, 2-acetamido-2-deoxy-beta-D-glucopyranose, GFP-MBP-solute carrier family 6 member 2
Authors:Ji, W.M, Wu, J.X.
Deposit date:2023-12-05
Release date:2024-06-26
Last modified:2024-09-25
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Substrate binding and inhibition mechanism of norepinephrine transporter.
Nature, 633, 2024
5YKF
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BU of 5ykf by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (3D class1 at 4.33A)
Descriptor: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ...
Authors:Chen, L, Wu, J.X.
Deposit date:2017-10-14
Release date:2018-04-18
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (4.33 Å)
Cite:Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YKG
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BU of 5ykg by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (Class2 at 4.57A)
Descriptor: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ...
Authors:Chen, L, Wu, J.X.
Deposit date:2017-10-14
Release date:2018-04-18
Last modified:2018-06-13
Method:ELECTRON MICROSCOPY (4.57 Å)
Cite:Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
6JPF
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BU of 6jpf by Molmil
Structure of atOSCA1.1 channel at 3.52A
Descriptor: Protein OSCA1
Authors:Chen, L, Zhang, M, Kang, Y, Wu, J.X.
Deposit date:2019-03-26
Release date:2019-04-10
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.52 Å)
Cite:Structure of the mechanosensitive OSCA channels.
Nat. Struct. Mol. Biol., 25, 2018
5YKE
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BU of 5yke by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (focused refinement on TM at 4.11A)
Descriptor: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11
Authors:Chen, L, Wu, J.X.
Deposit date:2017-10-14
Release date:2018-04-18
Last modified:2018-06-13
Method:ELECTRON MICROSCOPY (4.11 Å)
Cite:Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YW9
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BU of 5yw9 by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (class1 5.0A)
Descriptor: ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
Authors:Chen, L, Wu, J.X.
Deposit date:2017-11-29
Release date:2018-05-02
Last modified:2018-06-13
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YWB
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BU of 5ywb by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with Mg-ADP (CTD class2 at 5.2A)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ...
Authors:Chen, L, Wu, J.X.
Deposit date:2017-11-29
Release date:2018-05-30
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (5.2 Å)
Cite:Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YWC
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BU of 5ywc by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with Mg-ADP (CTD class1 at 4.3A)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ...
Authors:Chen, L, Wu, J.X.
Deposit date:2017-11-29
Release date:2018-05-02
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YW8
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BU of 5yw8 by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (all particles at 4.4A)
Descriptor: ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
Authors:Chen, L, Wu, J.X.
Deposit date:2017-11-29
Release date:2018-05-02
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5Z1F
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BU of 5z1f by Molmil
Structure of atOSCA3.1 channel
Descriptor: CSC1-like protein ERD4
Authors:Chen, L, Zhang, M, Kang, Y, Wu, J.X.
Deposit date:2017-12-26
Release date:2018-09-12
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Structure of the mechanosensitive OSCA channels.
Nat. Struct. Mol. Biol., 25, 2018
5YWD
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BU of 5ywd by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with Mg-ADP (focused refinement of SUR1 ABC transporter module at 4.22A)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family C member 8 isoform X2, MAGNESIUM ION
Authors:Chen, L, Wu, J.X.
Deposit date:2017-11-29
Release date:2018-05-02
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YW7
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BU of 5yw7 by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (focused refinement on SUR1 ABC transporter module at 4.4A)
Descriptor: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
Authors:Chen, L, Wu, J.X.
Deposit date:2017-11-29
Release date:2018-05-02
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YWA
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BU of 5ywa by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (CTD class 2 at 6.1A)
Descriptor: ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
Authors:Chen, L, Wu, J.X.
Deposit date:2017-11-29
Release date:2018-05-02
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
7D3E
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BU of 7d3e by Molmil
Cryo-EM structure of human DUOX1-DUOXA1 in low-calcium state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Dual oxidase 1, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Chen, L, Wu, J.X.
Deposit date:2020-09-19
Release date:2020-12-09
Last modified:2021-06-23
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structures of human dual oxidase 1 complex in low-calcium and high-calcium states.
Nat Commun, 12, 2021
7D3F
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BU of 7d3f by Molmil
Cryo-EM structure of human DUOX1-DUOXA1 in high-calcium state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Dual oxidase 1, ...
Authors:Chen, L, Wu, J.X.
Deposit date:2020-09-19
Release date:2020-12-09
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structures of human dual oxidase 1 complex in low-calcium and high-calcium states.
Nat Commun, 12, 2021

226707

數據於2024-10-30公開中

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