8F7Y
 
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8EW0
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8F4L
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1NYP
 | | 4th LIM domain of PINCH protein | | 分子名称: | PINCH protein, ZINC ION | | 著者 | Velyvis, A, Vaynberg, J, Vinogradova, O, Zhang, Y, Wu, C, Qin, J. | | 登録日 | 2003-02-13 | | 公開日 | 2003-07-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural and functional insights into PINCH LIM4 domain-mediated integrin signaling
Nat.Struct.Biol., 10, 2003
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4GHQ
 | | Crystal structure of EV71 3C proteinase | | 分子名称: | 3C proteinase | | 著者 | Chen, C, Wu, C, Cai, Q, Li, N, Peng, X, Cai, Y, Yin, K, Chen, X, Wang, X, Zhang, R, Liu, L, Chen, S, Li, J, Lin, T. | | 登録日 | 2012-08-08 | | 公開日 | 2013-06-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structures of Enterovirus 71 3C proteinase (strain E2004104-TW-CDC) and its complex with rupintrivir
Acta Crystallogr.,Sect.D, 69, 2013
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1X9X
 | | Solution Structure of Dimeric SAM Domain from MAPKKK Ste11 | | 分子名称: | Serine/threonine-protein kinase STE11 | | 著者 | Bhattacharjya, S, Xu, P, Gingras, R, Shaykhutdinov, R, Wu, C, Whiteway, M, Ni, F. | | 登録日 | 2004-08-24 | | 公開日 | 2005-08-30 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the dimeric SAM domain of MAPKKK Ste11 and its interactions with the adaptor protein Ste50 from the budding yeast: implications for Ste11 activation and signal transmission through the Ste50-Ste11 complex.
J.Mol.Biol., 344, 2004
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7CE2
 | | The Crystal structure of TeNT Hc complexed with neutralizing antibody | | 分子名称: | Tetanus toxin, neutralizing antibody heavy chain, neutralizing antibody light chain | | 著者 | Wang, X, Wang, Y, Wu, C, Yu, J, Liao, H. | | 登録日 | 2020-06-21 | | 公開日 | 2021-04-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Structural basis of tetanus toxin neutralization by native human monoclonal antibodies.
Cell Rep, 35, 2021
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5CHL
 | | Structural basis of H2A.Z recognition by YL1 histone chaperone component of SRCAP/SWR1 chromatin remodeling complex | | 分子名称: | Histone H2A.Z, Vacuolar protein sorting-associated protein 72 homolog | | 著者 | Shan, S, Liang, X, Pan, L, Wu, C, Zhou, Z. | | 登録日 | 2015-07-10 | | 公開日 | 2016-03-09 | | 最終更新日 | 2017-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.892 Å) | | 主引用文献 | Structural basis of H2A.Z recognition by SRCAP chromatin-remodeling subunit YL1
Nat.Struct.Mol.Biol., 23, 2016
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3HTP
 | | the hemagglutinin structure of an avian H1N1 influenza A virus in complex with LSTa | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | | 著者 | Wang, G, Li, A, Zhang, Q, Wu, C, Zhang, R, Cai, Q, Song, W, Yuen, K.-Y. | | 登録日 | 2009-06-12 | | 公開日 | 2009-08-11 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.96 Å) | | 主引用文献 | The hemagglutinin structure of an avian H1N1 influenza A virus
Virology, 392, 2009
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3HTQ
 | | the hemagglutinin structure of an avian H1N1 influenza A virus in complex with LSTc | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | | 著者 | Wang, G, Li, A, Zhang, Q, Wu, C, Zhang, R, Cai, Q, Song, W, Yuen, K.-Y. | | 登録日 | 2009-06-12 | | 公開日 | 2009-08-11 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.955 Å) | | 主引用文献 | The hemagglutinin structure of an avian H1N1 influenza A virus
Virology, 392, 2009
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3HTT
 | | The hemagglutinin structure of an avian H1N1 influenza A virus in complex with 2,3-sialyllactose | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | | 著者 | Wang, G, Li, A, Zhang, Q, Wu, C, Zhang, R, Cai, Q, Song, W, Yuen, K.-Y. | | 登録日 | 2009-06-12 | | 公開日 | 2009-08-11 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | The hemagglutinin structure of an avian H1N1 influenza A virus
Virology, 392, 2009
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3HTO
 | | the hemagglutinin structure of an avian H1N1 influenza A virus | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | | 著者 | Wang, G, Li, A, Zhang, Q, Wu, C, Zhang, R, Cai, Q, Song, W, Yuen, K.-Y. | | 登録日 | 2009-06-12 | | 公開日 | 2009-08-11 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | The hemagglutinin structure of an avian H1N1 influenza A virus
Virology, 392, 2009
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1MNN
 | | Structure of the sporulation specific transcription factor Ndt80 bound to DNA | | 分子名称: | 5'-D(*AP*GP*TP*TP*TP*TP*TP*GP*TP*GP*TP*CP*GP*C)-3', 5'-D(*TP*GP*CP*GP*AP*CP*AP*CP*AP*AP*AP*AP*AP*C)-3', NDT80 protein | | 著者 | Lamoureux, J.S, Stuart, D, Tsang, R, Wu, C, Glover, J.N. | | 登録日 | 2002-09-05 | | 公開日 | 2002-11-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structure of the sporulation-specific transcription factor Ndt80 bound to DNA
Embo J., 21, 2002
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1MN4
 | | Structure of Ndt80 (Residues 59-340) DNA-binding domain core | | 分子名称: | NDT80 PROTEIN | | 著者 | Lamoureux, J.S, Stuart, D, Tsang, R, Wu, C, Glover, J.N.M. | | 登録日 | 2002-09-04 | | 公開日 | 2002-11-06 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of the sporulation-specific transcription factor Ndt80 bound to DNA
Embo J., 21, 2002
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1U5S
 | | NMR structure of the complex between Nck-2 SH3 domain and PINCH-1 LIM4 domain | | 分子名称: | Cytoplasmic protein NCK2, PINCH protein, ZINC ION | | 著者 | Vaynberg, J, Fukuda, T, Vinogradova, O, Velyvis, A, Ng, L, Wu, C, Qin, J. | | 登録日 | 2004-07-28 | | 公開日 | 2005-04-05 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of an ultraweak protein-protein complex and its crucial role in regulation of cell morphology and motility.
Mol.Cell, 17, 2005
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8HI2
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8HHS
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8SZI
 | | Cryo-EM structure of PAM-free human calcium-sensing receptor CaSR-Gi complex in lipid nanodiscs | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | He, F, Wu, C, Gao, Y, Skiniotis, G. | | 登録日 | 2023-05-29 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Allosteric modulation and G-protein selectivity of the Ca 2+ -sensing receptor.
Nature, 626, 2024
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8SZF
 | | Cryo-EM structure of cinacalcet-bound active-state human calcium-sensing receptor CaSR in lipid nanodiscs | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | He, F, Wu, C, Gao, Y, Skiniotis, G. | | 登録日 | 2023-05-29 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Allosteric modulation and G-protein selectivity of the Ca 2+ -sensing receptor.
Nature, 626, 2024
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8SZG
 | | Cryo-EM structure of cinacalcet-bound human calcium-sensing receptor CaSR-Gq complex in lipid nanodiscs | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | He, F, Wu, C, Gao, Y, Skiniotis, G. | | 登録日 | 2023-05-29 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Allosteric modulation and G-protein selectivity of the Ca 2+ -sensing receptor.
Nature, 626, 2024
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8SZH
 | | Cryo-EM structure of cinacalcet-bound human calcium-sensing receptor CaSR-Gi complex in lipid nanodiscs | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | He, F, Wu, C, Gao, Y, Skiniotis, G. | | 登録日 | 2023-05-29 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Allosteric modulation and G-protein selectivity of the Ca 2+ -sensing receptor.
Nature, 626, 2024
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7RSP
 | | Structure of the VPS34 kinase domain with compound 14 | | 分子名称: | (7R,8R)-2-[(3R)-3-methylmorpholin-4-yl]-7-(propan-2-yl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one, GLYCEROL, Phosphatidylinositol 3-kinase catalytic subunit type 3 | | 著者 | Hu, D.X, Patel, S, Chen, H, Wang, S, Staben, S, Dimitrova, Y.N, Wallweber, H.A, Lee, J.Y, Chan, G.K.Y, Sneeringer, C.J, Prangley, M.S, Moffat, J.G, Wu, C, Schutt, L.K, Salphati, L, Pang, J, McNamara, E, Huang, H, Chen, Y, Wang, Y, Zhao, W, Lim, J, Murthy, A, Siu, M. | | 登録日 | 2021-08-11 | | 公開日 | 2021-11-24 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Structure-Based Design of Potent, Selective, and Orally Bioavailable VPS34 Kinase Inhibitors.
J.Med.Chem., 65, 2022
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7RSV
 | | Structure of the VPS34 kinase domain with compound 5 | | 分子名称: | (5aS,8aR,9S)-2-[(3R)-3-methylmorpholin-4-yl]-5,5a,6,7,8,8a-hexahydro-4H-cyclopenta[e]pyrazolo[1,5-a]pyrazin-4-one, GLYCEROL, Phosphatidylinositol 3-kinase catalytic subunit type 3, ... | | 著者 | Hu, D.X, Patel, S, Chen, H, Wang, S, Staben, S, Dimitrova, Y.N, Wallweber, H.A, Lee, J.Y, Chan, G.K.Y, Sneeringer, C.J, Prangley, M.S, Moffat, J.G, Wu, C, Schutt, L.K, Salphati, L, Pang, J, McNamara, E, Huang, H, Chen, Y, Wang, Y, Zhao, W, Lim, J, Murthy, A, Siu, M. | | 登録日 | 2021-08-11 | | 公開日 | 2021-11-24 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Structure-Based Design of Potent, Selective, and Orally Bioavailable VPS34 Kinase Inhibitors.
J.Med.Chem., 65, 2022
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7RSJ
 | | Structure of the VPS34 kinase domain with compound 14 | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, N-{4-[(7R,8R)-4-oxo-7-(propan-2-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-yl]pyridin-2-yl}cyclopropanecarboxamide, ... | | 著者 | Hu, D.X, Patel, S, Chen, H, Wang, S, Staben, S, Dimitrova, Y.N, Wallweber, H.A, Lee, J.Y, Chan, G.K.Y, Sneeringer, C.J, Prangley, M.S, Moffat, J.G, Wu, C, Schutt, L.K, Salphati, L, Pang, J, McNamara, E, Huang, H, Chen, Y, Wang, Y, Zhao, W, Lim, J, Murthy, A, Siu, M. | | 登録日 | 2021-08-11 | | 公開日 | 2021-11-24 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.881 Å) | | 主引用文献 | Structure-Based Design of Potent, Selective, and Orally Bioavailable VPS34 Kinase Inhibitors.
J.Med.Chem., 65, 2022
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5Z0V
 | | Structural insight into the Zika virus capsid encapsulating the viral genome | | 分子名称: | Extracellular solute-binding protein family 1,viral genome protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | 著者 | Li, T, Zhao, Q, Yang, X, Chen, C, Yang, K, Wu, C, Zhang, T, Duan, Y, Xue, X, Mi, K, Ji, X, Wang, Z, Yang, H. | | 登録日 | 2017-12-21 | | 公開日 | 2018-04-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.913 Å) | | 主引用文献 | Structural insight into the Zika virus capsid encapsulating the viral genome.
Cell Res., 28, 2018
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