6GWX
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![BU of 6gwx by Molmil](/molmil-images/mine/6gwx) | Stabilising and Understanding a Miniprotein by Rational Design. | Descriptor: | Optimised PPa-TYR | Authors: | Porter Goff, K.L, Williams, C, Baker, E.G, Nicol, D, Samphire, J.L, Zieleniewski, F.L, Crump, M.P, Woolfson, D.N. | Deposit date: | 2018-06-26 | Release date: | 2019-07-10 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Stabilizing and Understanding a Miniprotein by Rational Redesign. Biochemistry, 58, 2019
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7BIM
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![BU of 7bim by Molmil](/molmil-images/mine/7bim) | A de novo designed nonameric coiled coil, CC-Type2-(GgLaId)4 | Descriptor: | GLYCEROL, ISOPROPYL ALCOHOL, Nonameric de novo coiled coil CC-Type2-(GgLaId)4 | Authors: | Shelley, K.L, Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. | Deposit date: | 2021-01-12 | Release date: | 2021-04-21 | Last modified: | 2021-11-17 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Coiled coils 9-to-5: rational de novo design of alpha-helical barrels with tunable oligomeric states. Chem Sci, 12, 2021
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7BAS
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![BU of 7bas by Molmil](/molmil-images/mine/7bas) | A de novo pentameric coiled-coil assembly: CC-Type2-(TgLaId)4-W19BrPhe. | Descriptor: | CC-Type2-(TgLaId)4-W19BrPhe. | Authors: | Martin, F.J.O, Dawson, W.M, Shelley, K, Brady, R.L, Woolfson, D.N. | Deposit date: | 2020-12-16 | Release date: | 2021-04-28 | Last modified: | 2021-11-17 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Coiled coils 9-to-5: rational de novo design of alpha-helical barrels with tunable oligomeric states. Chem Sci, 12, 2021
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7BAU
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![BU of 7bau by Molmil](/molmil-images/mine/7bau) | A de novo pentameric coiled-coil assembly: CC-Type2-(TgIaId)4-W19BrPhe. | Descriptor: | CC-Type2-(TgLaId)4-W19BrPhe. | Authors: | Martin, F.J.O, Dawson, W.M, Shelley, K, Brady, R.L, Woolfson, D.N. | Deposit date: | 2020-12-16 | Release date: | 2021-04-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Coiled coils 9-to-5: rational de novo design of alpha-helical barrels with tunable oligomeric states. Chem Sci, 12, 2021
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7BAV
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![BU of 7bav by Molmil](/molmil-images/mine/7bav) | A de novo pentameric coiled-coil assembly: CC-Type2-(TgLaId)4-W19BrPhe. | Descriptor: | CC-Type2-(TgLaId)4-W19BrPhe | Authors: | Martin, F.J.O, Dawson, W.M, Shelley, K, Brady, R.L, Woolfson, D.N. | Deposit date: | 2020-12-16 | Release date: | 2021-04-28 | Last modified: | 2021-11-17 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Coiled coils 9-to-5: rational de novo design of alpha-helical barrels with tunable oligomeric states. Chem Sci, 12, 2021
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7BAW
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![BU of 7baw by Molmil](/molmil-images/mine/7baw) | A heptameric barrel state of a de novo coiled-coil assembly: CC-Type2-(GgIaId)4 | Descriptor: | CC-Type2-(GgIaId)4, GLYCEROL, N-PROPANOL | Authors: | Martin, F.J.O, Dawson, W.M, Brady, R.L, Woolfson, D.N. | Deposit date: | 2020-12-16 | Release date: | 2021-04-28 | Last modified: | 2021-11-17 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Coiled coils 9-to-5: rational de novo design of alpha-helical barrels with tunable oligomeric states. Chem Sci, 12, 2021
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3E8W
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![BU of 3e8w by Molmil](/molmil-images/mine/3e8w) | Crystal Structure of Epiphyas postvittana Takeout 1 | Descriptor: | Takeout-like protein 1, Ubiquinone-8 | Authors: | Hamiaux, C, Stanley, D, Greenwood, D.R, Baker, E.N, Newcomb, R.D. | Deposit date: | 2008-08-20 | Release date: | 2008-12-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of Epiphyas postvittana takeout 1 with bound ubiquinone supports a role as ligand carriers for takeout proteins in insects J.Biol.Chem., 284, 2009
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7A1T
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![BU of 7a1t by Molmil](/molmil-images/mine/7a1t) | A collapsed hexameric state of a de novo coiled-coil assembly: CC-Type2-(GgLaId)4-W19BrPhe. | Descriptor: | ACETATE ION, CADMIUM ION, CC-Type2-(GgLaId)4-W19BrPhe, ... | Authors: | Rhys, G.G, Brady, R.L, Woolfson, D.N. | Deposit date: | 2020-08-14 | Release date: | 2021-05-19 | Last modified: | 2021-11-17 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Coiled coils 9-to-5: rational de novo design of alpha-helical barrels with tunable oligomeric states. Chem Sci, 12, 2021
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1B8W
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![BU of 1b8w by Molmil](/molmil-images/mine/1b8w) | DEFENSIN-LIKE PEPTIDE 1 | Descriptor: | PROTEIN (DEFENSIN-LIKE PEPTIDE 1) | Authors: | Torres, A.M, Wang, X, Fletcher, J.I, Alewood, D, Alewood, P.F, Smith, R, Simpson, R.J, Nicholson, G.M, Sutherland, S.K, Gallagher, C.H, King, G.F, Kuchel, P.W. | Deposit date: | 1999-02-02 | Release date: | 1999-09-15 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of a defensin-like peptide from platypus venom. Biochem.J., 341, 1999
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9BKK
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![BU of 9bkk by Molmil](/molmil-images/mine/9bkk) | Cholecystokinin 1 receptor (CCK1R) sterol 7M mutant, Gq chimera (mGsqi) complex | Descriptor: | Cholecystokinin receptor type A, Cholecystokinin-8, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Harikumar, K.G, Zhao, P, Cary, B.P, Xu, X, Desai, A.J, Mobbs, J.I, Toufaily, C, Furness, S.G.B, Christopoulos, A, Belousoff, M.J, Wootten, D, Sexton, P.M, Miller, L.J. | Deposit date: | 2024-04-29 | Release date: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.51 Å) | Cite: | Cholesterol-dependent dynamic changes in the conformation of the type 1 cholecystokinin receptor affect ligand binding and G protein coupling To Be Published
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5EZA
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![BU of 5eza by Molmil](/molmil-images/mine/5eza) | |
5EZE
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![BU of 5eze by Molmil](/molmil-images/mine/5eze) | |
5EZ9
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![BU of 5ez9 by Molmil](/molmil-images/mine/5ez9) | |
4EDL
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![BU of 4edl by Molmil](/molmil-images/mine/4edl) | Crystal structure of beta-parvin CH2 domain | Descriptor: | 1,2-ETHANEDIOL, Beta-parvin | Authors: | Stiegler, A.L, Draheim, K.M, Li, X, Chayen, N.E, Calderwood, D.A, Boggon, T.J. | Deposit date: | 2012-03-27 | Release date: | 2012-08-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for paxillin binding and focal adhesion targeting of beta-parvin. J.Biol.Chem., 287, 2012
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4H7R
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![BU of 4h7r by Molmil](/molmil-images/mine/4h7r) | Crystal structure of a parallel 4-helix coiled coil CC-Hex-II | Descriptor: | 1,4-DIETHYLENE DIOXIDE, CC-Hex-II, GLYCEROL | Authors: | Chi, B, Zaccai, N.R, Brady, R.L, Woolfson, D.N. | Deposit date: | 2012-09-20 | Release date: | 2014-02-05 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | TBA To be Published
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7BAT
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![BU of 7bat by Molmil](/molmil-images/mine/7bat) | A hexameric barrel state of a de novo coiled-coil assembly: CC-Type2-(GgIaId)4 | Descriptor: | CC-Type2-(GgIaId)4, N-PROPANOL | Authors: | Martin, F.J.O, Dawson, W.M, Shelley, K, Brady, R.L, Woolfson, D.N. | Deposit date: | 2020-12-16 | Release date: | 2021-04-28 | Last modified: | 2021-11-17 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Coiled coils 9-to-5: rational de novo design of alpha-helical barrels with tunable oligomeric states. Chem Sci, 12, 2021
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5UZ7
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![BU of 5uz7 by Molmil](/molmil-images/mine/5uz7) | Volta phase plate cryo-electron microscopy structure of a calcitonin receptor-heterotrimeric Gs protein complex | Descriptor: | Calcitonin receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Liang, Y.L, Khoshouei, M, Radjainia, M, Zhang, Y, Glukhova, A, Tarrasch, J, Thal, D.M, Furness, S.G.B, Christopoulos, G, Coudrat, T, Danev, R, Baumeister, W, Miller, L.J, Christopoulos, A, Kobilka, B.K, Wootten, D, Skiniotis, G, Sexton, P.M. | Deposit date: | 2017-02-24 | Release date: | 2017-05-03 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Phase-plate cryo-EM structure of a class B GPCR-G-protein complex. Nature, 546, 2017
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1MK7
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![BU of 1mk7 by Molmil](/molmil-images/mine/1mk7) | CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA | Descriptor: | Integrin Beta3, TALIN | Authors: | Garcia-Alvarez, B, De Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C. | Deposit date: | 2002-08-28 | Release date: | 2003-01-28 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Determinants of Integrin Recognition by Talin Mol.Cell, 11, 2003
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4KVV
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![BU of 4kvv by Molmil](/molmil-images/mine/4kvv) | Crystal structure of an alkylated Cys mutant of CC-Hex | Descriptor: | 6-HELIX COILED COIL CC-HEX-L24C PEPTIDE with an alkylated Cys mutation | Authors: | Burton, A.J, Agnew, C, Brady, R.L, Woolfson, D.N. | Deposit date: | 2013-05-23 | Release date: | 2013-08-21 | Last modified: | 2013-09-11 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Accessibility, Reactivity, and Selectivity of Side Chains within a Channel of de Novo Peptide Assembly. J.Am.Chem.Soc., 135, 2013
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1MK9
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![BU of 1mk9 by Molmil](/molmil-images/mine/1mk9) | CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA | Descriptor: | Integrin Beta3, TALIN | Authors: | Garcia-Alvarez, B, De Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C. | Deposit date: | 2002-08-28 | Release date: | 2003-01-28 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Determinants of Integrin Recognition by Talin Mol.Cell, 11, 2003
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4HI9
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![BU of 4hi9 by Molmil](/molmil-images/mine/4hi9) | 1.2 structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain collected at wavelength 0.91974 | Descriptor: | IODIDE ION, Integrin-linked protein kinase, LIM and senescent cell antigen-like-containing domain protein 1, ... | Authors: | Stiegler, A.L, Jakoncic, J, Stojanoff, V, Chiswell, B.P, Calderwood, D.A, Boggon, T.J. | Deposit date: | 2012-10-11 | Release date: | 2013-12-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.203 Å) | Cite: | 1.2 structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain collected at wavelength 0.91974 To be Published
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5LO4
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![BU of 5lo4 by Molmil](/molmil-images/mine/5lo4) | Engineering protein stability with atomic precision in a monomeric miniprotein | Descriptor: | PPa-CH3 | Authors: | Baker, E.G, Williams, C, Hudson, K.L, Bartlett, G.G, Heal, J.W, Sessions, R.B, Crump, M.P, Woolfson, D.N. | Deposit date: | 2016-08-08 | Release date: | 2017-05-17 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Engineering protein stability with atomic precision in a monomeric miniprotein. Nat. Chem. Biol., 13, 2017
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5LO2
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![BU of 5lo2 by Molmil](/molmil-images/mine/5lo2) | Engineering protein stability with atomic precision in a monomeric miniprotein | Descriptor: | PPaTyr | Authors: | Baker, E.G, Hudson, K.L, Williams, C, Bartlett, G.G, Heal, J.W, Sessions, R.B, Crump, M.P, Woolfson, D.N. | Deposit date: | 2016-08-08 | Release date: | 2017-05-17 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Engineering protein stability with atomic precision in a monomeric miniprotein. Nat. Chem. Biol., 13, 2017
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5LO3
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![BU of 5lo3 by Molmil](/molmil-images/mine/5lo3) | Engineering protein stability with atomic precision in a monomeric miniprotein | Descriptor: | PPaOMe | Authors: | Baker, E.G, Hudson, K.L, Williams, C, Bartlett, G.G, Heal, J.W, Sessions, R.B, Crump, M.P, Woolfson, D.N. | Deposit date: | 2016-08-08 | Release date: | 2017-05-17 | Last modified: | 2023-11-15 | Method: | SOLUTION NMR | Cite: | Engineering protein stability with atomic precision in a monomeric miniprotein. Nat. Chem. Biol., 13, 2017
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5EZC
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![BU of 5ezc by Molmil](/molmil-images/mine/5ezc) | |