6CT6
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![BU of 6ct6 by Molmil](/molmil-images/mine/6ct6) | Crystal structure of lactate dehydrogenase from Eimeria maxima with NADH and oxamate | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Lactate dehydrogenase, OXAMIC ACID, ... | Authors: | Wirth, J.D, Xu, C, Theobald, D.L. | Deposit date: | 2018-03-22 | Release date: | 2019-03-27 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.705 Å) | Cite: | The Mechanistic, Structural, and Evolutionary Origin of Lactate Dehydrogenase Substrate Specificity in Apicomplexa To Be Published
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8AQF
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![BU of 8aqf by Molmil](/molmil-images/mine/8aqf) | CRYSTAL STRUCTURE OF HUMAN MONOGLYCERIDE LIPASE WITH COMPOUND LEI-515 | Descriptor: | 1-[(~{R})-[2-chloranyl-4-[(2~{S},3~{S})-4-(3-chlorophenyl)-2,3-dimethyl-piperazin-1-yl]carbonyl-phenyl]sulfinyl]-3,3-bis(fluoranyl)pentan-2-one, Monoglyceride lipase | Authors: | Jiang, M, Huizenga, M, Wirt, J, Paloczi, J, Amedi, A, van der Berg, R, Benz, J, Collin, L, Deng, H, Driever, W, Florea, B, Grether, U, Janssen, A, Heitman, L, Lam, T.W, Mohr, F, Pavlovic, A, Ruf, I, Rutjes, H, Stevens, F, van der Vliet, D, van der Wel, T, Wittwer, M, Boeckel, C, Pacher, P, Hohmann, A, van der Stelt, M. | Deposit date: | 2022-08-12 | Release date: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Discovery of a peripheral restricted, reversible monoacylglycerol lipase inhibitor that reduces liver injury and chemotherapy-induced neuropathy To Be Published
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7NBN
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![BU of 7nbn by Molmil](/molmil-images/mine/7nbn) | Allostery through DNA drives phenotype switching | Descriptor: | AddAB promoter | Authors: | Rosenblum, G, Elad, N, Rozenberg, H, Wiggers, F, Jungwirth, J, Hofmann, H. | Deposit date: | 2021-01-27 | Release date: | 2021-04-07 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (7 Å) | Cite: | Allostery through DNA drives phenotype switching. Nat Commun, 12, 2021
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8TFN
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![BU of 8tfn by Molmil](/molmil-images/mine/8tfn) | Structure of anti-TCRvbeta6-5 antibody in complex with the cognate TCR | Descriptor: | Anti-TCRVb6-5 Fab heavy chain, Anti-TCRVb6-5 Fab light chain, TRAV12-3, ... | Authors: | Katragadda, M, Servatalab, R, Wirth, J. | Deposit date: | 2023-07-11 | Release date: | 2023-11-08 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Innate TCR beta-chain engagement drives human T cells toward distinct memory-like effector phenotypes with immunotherapeutic potentials. Sci Adv, 9, 2023
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7SJ6
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![BU of 7sj6 by Molmil](/molmil-images/mine/7sj6) | T4 Lysozyme L99A/M102H with 1,2-Azaborine bound | Descriptor: | 1,2-dihydro-1,2-azaborinine, 2-HYDROXYETHYL DISULFIDE, ACETATE ION, ... | Authors: | Yao, L, Wirth, J. | Deposit date: | 2021-10-16 | Release date: | 2022-10-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | T4 Lysozyme L99A/M102H with 1,2-Azaborine bound to be published
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6Z0S
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![BU of 6z0s by Molmil](/molmil-images/mine/6z0s) | Allostery through DNA drives phenotype switching | Descriptor: | comG promoter DNA - strand A, comG promoter DNA - strand B | Authors: | Rosenblum, G, Elad, N, Rozenberg, H, Wiggers, F, Jungwirth, J, Hofmann, H. | Deposit date: | 2020-05-11 | Release date: | 2021-04-07 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (5.7 Å) | Cite: | Allostery through DNA drives phenotype switching. Nat Commun, 12, 2021
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6VDH
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![BU of 6vdh by Molmil](/molmil-images/mine/6vdh) | |
6VDI
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![BU of 6vdi by Molmil](/molmil-images/mine/6vdi) | |
6VDJ
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![BU of 6vdj by Molmil](/molmil-images/mine/6vdj) | Crystal structure of ancestral apicomplexan lactate dehydrogenase with sulfate and NADH4. | Descriptor: | 1,4,5,6-TETRAHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, SULFATE ION, lactate dehydrogenase | Authors: | Theobald, D.L, Wirth, J.D, Classen, S, Perlmutter, N. | Deposit date: | 2019-12-27 | Release date: | 2020-01-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mechanism of Bifunctionality in an Ancestral Apicomplexan Malate/Lactate Dehydrogenase To Be Published
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5OMF
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![BU of 5omf by Molmil](/molmil-images/mine/5omf) | Closed, ternary structure of KOD DNA polymerase | Descriptor: | 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*CP*AP*C)-3'), ... | Authors: | Kropp, H.M, Betz, K, Wirth, J, Diederichs, K, Marx, A. | Deposit date: | 2017-07-31 | Release date: | 2017-12-20 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.092 Å) | Cite: | Crystal structures of ternary complexes of archaeal B-family DNA polymerases. PLoS ONE, 12, 2017
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