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PDB: 888 results

6WO3
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Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 6a bound to broadly neutralizing antibody U1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
Authors:Tzarum, N, Wilson, I.A, Law, M.
Deposit date:2020-04-24
Release date:2020-08-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.382 Å)
Cite:An alternate conformation of HCV E2 neutralizing face as an additional vaccine target.
Sci Adv, 6, 2020
6WOQ
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Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 1a bound to neutralizing antibody HC1AM and non neutralizing antibody E1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
Authors:Tzarum, N, Wilson, I.A, Law, M.
Deposit date:2020-04-25
Release date:2020-08-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.667 Å)
Cite:An alternate conformation of HCV E2 neutralizing face as an additional vaccine target.
Sci Adv, 6, 2020
6XKQ
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Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CV07-250
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CV07-250 Heavy Chain, CV07-250 Light Chain, ...
Authors:Yuan, M, Liu, H, Zhu, X, Wu, N.C, Wilson, I.A.
Deposit date:2020-06-26
Release date:2020-10-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model.
Cell, 183, 2020
8GB6
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BU of 8gb6 by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody 21B6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 21B6 Heavy chain, 21B6 Light chain, ...
Authors:Yuan, M, Wilson, I.A.
Deposit date:2023-02-24
Release date:2023-05-24
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Broadly neutralizing antibodies against sarbecoviruses generated by immunization of macaques with an AS03-adjuvanted COVID-19 vaccine.
Sci Transl Med, 15, 2023
8GB7
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Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody 20A7
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 20A7 Heavy chain, 20A7 Light chain, ...
Authors:Yuan, M, Wilson, I.A.
Deposit date:2023-02-24
Release date:2023-05-24
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Broadly neutralizing antibodies against sarbecoviruses generated by immunization of macaques with an AS03-adjuvanted COVID-19 vaccine.
Sci Transl Med, 15, 2023
8GB8
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Crystal structure of SARS-CoV-2 BA.2 receptor binding domain in complex with neutralizing antibody 20A7
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 20A7 Heavy chain, ...
Authors:Yuan, M, Wilson, I.A.
Deposit date:2023-02-24
Release date:2023-05-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Broadly neutralizing antibodies against sarbecoviruses generated by immunization of macaques with an AS03-adjuvanted COVID-19 vaccine.
Sci Transl Med, 15, 2023
8GB5
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Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody 25F9
Descriptor: 25F9 Heavy chain, 25F9 Light chain, BICINE, ...
Authors:Yuan, M, Zhu, X, Wilson, I.A.
Deposit date:2023-02-24
Release date:2023-05-24
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Broadly neutralizing antibodies against sarbecoviruses generated by immunization of macaques with an AS03-adjuvanted COVID-19 vaccine.
Sci Transl Med, 15, 2023
8GBX
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Crystal structure of PC39-50I, an anti-HIV broadly neutralizing antibody
Descriptor: PC39-50I Fab heavy chain, PC39-50I Fab light chain
Authors:Murrell, S, Omorodion, O, Wilson, I.A.
Deposit date:2023-02-28
Release date:2023-06-07
Last modified:2023-07-12
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies.
Plos Pathog., 19, 2023
8GBY
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Crystal structure of PC39-50E, an anti-HIV broadly neutralizing antibody
Descriptor: GLYCEROL, PC39-50E Fab heavy chain, PC39-50E Fab light chain
Authors:Murrell, S, Omorodion, O, Wilson, I.A.
Deposit date:2023-02-28
Release date:2023-06-07
Last modified:2023-07-12
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies.
Plos Pathog., 19, 2023
8GBW
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Crystal structure of PC39-23D, an anti-HIV broadly neutralizing antibody
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, PC39-23D Fab heavy chain, ...
Authors:Murrell, S, Omorodion, O, Wilson, I.A.
Deposit date:2023-02-28
Release date:2023-06-07
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies.
Plos Pathog., 19, 2023
8GC0
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Crystal structure of PC39-50L, an anti-HIV broadly neutralizing antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PC39-50L Fab heavy chain, PC39-50L Fab light chain
Authors:Murrell, S, Omorodion, O, Wilson, I.A.
Deposit date:2023-02-28
Release date:2023-06-07
Last modified:2023-07-12
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies.
Plos Pathog., 19, 2023
8GBV
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Crystal structure of PC39-17A, an anti-HIV broadly neutralizing antibody
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, PC39-17A Fab heavy chain, ...
Authors:Murrell, S, Omorodion, O, Wilson, I.A.
Deposit date:2023-02-28
Release date:2023-06-07
Last modified:2023-07-12
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies.
Plos Pathog., 19, 2023
8GC1
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Crystal structure of the unmutated common ancestor (UCA) of the PC39-1 anti-HIV broadly neutralizing antibody lineage
Descriptor: PC39-1 UCA Fab heavy chain, PC39-1 UCA Fab light chain
Authors:Murrell, S, Omorodion, O, Wilson, I.A.
Deposit date:2023-02-28
Release date:2023-06-07
Last modified:2023-07-12
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies.
Plos Pathog., 19, 2023
8GBZ
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BU of 8gbz by Molmil
Crystal structure of PC39-55C, an anti-HIV broadly neutralizing antibody
Descriptor: DI(HYDROXYETHYL)ETHER, PC39-55C Fab heavy chain, PC39-55C Fab light chain
Authors:Murrell, S, Omorodion, O, Wilson, I.A.
Deposit date:2023-02-28
Release date:2023-06-07
Last modified:2023-07-12
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies.
Plos Pathog., 19, 2023
3TV3
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BU of 3tv3 by Molmil
Crystal structure of broad and potent HIV-1 neutralizing antibody PGT128 in complex with Man9
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AMYLAMINE, GLYCEROL, ...
Authors:Pejchal, R, Wilson, I.A.
Deposit date:2011-09-19
Release date:2011-10-19
Last modified:2021-04-28
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield.
Science, 334, 2011
3U1S
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BU of 3u1s by Molmil
Crystal structure of human Fab PGT145, a broadly reactive and potent HIV-1 neutralizing antibody
Descriptor: Fab PGT145 Heavy chain, Fab PGT145 Light chain, GLYCEROL, ...
Authors:Julien, J.-P, Diwanji, D, Burton, D.R, Wilson, I.A.
Deposit date:2011-09-30
Release date:2011-12-07
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
3UBQ
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BU of 3ubq by Molmil
Influenza hemagglutinin from the 2009 pandemic in complex with ligand 3SLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose, ...
Authors:Xu, R, Wilson, I.A.
Deposit date:2011-10-24
Release date:2011-11-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Characterization of the Hemagglutinin Receptor Specificity from the 2009 H1N1 Influenza Pandemic.
J.Virol., 86, 2012
3UBN
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BU of 3ubn by Molmil
Influenza hemagglutinin from the 2009 pandemic in complex with ligand 6SLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ...
Authors:Xu, R, Wilson, I.A.
Deposit date:2011-10-24
Release date:2011-11-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5079 Å)
Cite:Structural Characterization of the Hemagglutinin Receptor Specificity from the 2009 H1N1 Influenza Pandemic.
J.Virol., 86, 2012
3TWI
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BU of 3twi by Molmil
Variable Lymphocyte Receptor Recognition of the Immunodominant Glycoprotein of Bacillus anthracis Spores
Descriptor: BclA protein, GLYCEROL, Variable lymphocyte receptor B
Authors:Kirchdoerfer, R.N, Herrin, B.R, Han, B.W, Turnbough Jr, C.L, Cooper, M.D, Wilson, I.A.
Deposit date:2011-09-21
Release date:2012-03-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Variable Lymphocyte Receptor Recognition of the Immunodominant Glycoprotein of Bacillus anthracis Spores.
Structure, 20, 2012
3TYJ
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BU of 3tyj by Molmil
Bacillus collagen-like protein of anthracis P159S mutant
Descriptor: BclA protein
Authors:Kirchdoerfer, R.N, Herrin, B.R, Han, B.W, Turnbough Jr, C.L, Cooper, M.D, Wilson, I.A.
Deposit date:2011-09-26
Release date:2012-03-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Variable Lymphocyte Receptor Recognition of the Immunodominant Glycoprotein of Bacillus anthracis Spores.
Structure, 20, 2012
3T0W
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BU of 3t0w by Molmil
Fluorogen activating protein M8VL in complex with dimethylindole red
Descriptor: 1-(3-sulfopropyl)-4-[(1E,3E)-3-(1,3,3-trimethyl-1,3-dihydro-2H-indol-2-ylidene)prop-1-en-1-yl]quinolinium, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, CHLORIDE ION, ...
Authors:Stanfield, R, Senutovitch, N, Bhattacharyya, S, Rule, G, Wilson, I.A, Armitage, B, Waggoner, A.S, Berget, P.
Deposit date:2011-07-20
Release date:2012-03-21
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.501 Å)
Cite:A variable light domain fluorogen activating protein homodimerizes to activate dimethylindole red.
Biochemistry, 51, 2012
3SDY
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BU of 3sdy by Molmil
Crystal Structure of Broadly Neutralizing Antibody CR8020 Bound to the Influenza A H3 Hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody CR8020, Heavy Chain, ...
Authors:Ekiert, D.C, Wilson, I.A.
Deposit date:2011-06-09
Release date:2011-07-20
Last modified:2021-04-07
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:A highly conserved neutralizing epitope on group 2 influenza A viruses.
Science, 333, 2011
3T0V
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BU of 3t0v by Molmil
Unliganded fluorogen activating protein M8VL
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, ...
Authors:Stanfield, R, Senutovitch, N, Bhattacharyya, S, Rule, G, Wilson, I.A, Armitage, B, Waggoner, A.S, Berget, P.
Deposit date:2011-07-20
Release date:2012-03-21
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.451 Å)
Cite:A variable light domain fluorogen activating protein homodimerizes to activate dimethylindole red.
Biochemistry, 51, 2012
3UN9
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Crystal structure of an immune receptor
Descriptor: NLR family member X1, PLATINUM (II) ION
Authors:Hong, M, Yoon, S.I, Wilson, I.A.
Deposit date:2011-11-15
Release date:2012-03-28
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure and Functional Characterization of the RNA-Binding Element of the NLRX1 Innate Immune Modulator.
Immunity, 36, 2012
3TCT
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Structure of wild-type TTR in complex with tafamidis
Descriptor: 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid, Transthyretin
Authors:Connelly, S, Kelly, J.W, Wilson, I.A.
Deposit date:2011-08-09
Release date:2012-05-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade.
Proc.Natl.Acad.Sci.USA, 109, 2012

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