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PDB: 238 results

6GXP
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BU of 6gxp by Molmil
Cryo-EM structure of a rotated E. coli 70S ribosome in complex with RF3-GDPCP(RF3-only)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Graf, M, Huter, P, Maracci, C, Peterek, M, Rodnina, M.V, Wilson, D.N.
Deposit date:2018-06-27
Release date:2018-08-15
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1.
Nat Commun, 9, 2018
6GXO
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BU of 6gxo by Molmil
Cryo-EM structure of a rotated E. coli 70S ribosome in complex with RF3-GDPCP, RF1(GAQ) and P/E-tRNA (State IV)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Graf, M, Huter, P, Maracci, C, Peterek, M, Rodnina, M.V, Wilson, D.N.
Deposit date:2018-06-27
Release date:2018-08-15
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1.
Nat Commun, 9, 2018
5L3P
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BU of 5l3p by Molmil
Cryo-EM structure of stringent response factor RelA bound to ErmCL-stalled ribosome complex
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Arenz, S, Wilson, D.N.
Deposit date:2016-05-24
Release date:2016-07-20
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:The stringent factor RelA adopts an open conformation on the ribosome to stimulate ppGpp synthesis.
Nucleic Acids Res., 44, 2016
6YST
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BU of 6yst by Molmil
Structure of the P+9 ArfB-ribosome complex with P/E hybrid tRNA in the post-hydrolysis state
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Chan, K.-H, Petrychenko, V, Mueller, C, Maracci, C, Holtkamp, W, Wilson, D.N, Fischer, N, Rodnina, M.V.
Deposit date:2020-04-23
Release date:2020-08-19
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Mechanism of ribosome rescue by alternative ribosome-rescue factor B.
Nat Commun, 11, 2020
6YSS
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BU of 6yss by Molmil
Structure of the P+9 ArfB-ribosome complex in the post-hydrolysis state
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Chan, K.-H, Petrychenko, V, Mueller, C, Maracci, C, Holtkamp, W, Wilson, D.N, Fischer, N, Rodnina, M.V.
Deposit date:2020-04-23
Release date:2020-08-19
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Mechanism of ribosome rescue by alternative ribosome-rescue factor B.
Nat Commun, 11, 2020
6GWT
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BU of 6gwt by Molmil
Cryo-EM structure of an E. coli 70S ribosome in complex with RF3-GDPCP, RF1(GAQ) and Pint-tRNA (State I)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Graf, M, Huter, P, Maracci, C, Peterek, M, Rodnina, M.V, Wilson, D.N.
Deposit date:2018-06-25
Release date:2018-08-15
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1.
Nat Commun, 9, 2018
6GXN
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BU of 6gxn by Molmil
Cryo-EM structure of an E. coli 70S ribosome in complex with RF3-GDPCP, RF1(GAQ) and Pint-tRNA (State III)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Graf, M, Huter, P, Maracci, C, Peterek, M, Rodnina, M.V, Wilson, D.N.
Deposit date:2018-06-27
Release date:2018-08-15
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1.
Nat Commun, 9, 2018
6GXM
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BU of 6gxm by Molmil
Cryo-EM structure of an E. coli 70S ribosome in complex with RF3-GDPCP, RF1(GAQ) and Pint-tRNA (State II)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Graf, M, Huter, P, Maracci, C, Peterek, M, Rodnina, M.V, Wilson, D.N.
Deposit date:2018-06-27
Release date:2018-08-22
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1.
Nat Commun, 9, 2018
6YSU
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BU of 6ysu by Molmil
Structure of the P+0 ArfB-ribosome complex in the post-hydrolysis state
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Chan, K.-H, Petrychenko, V, Mueller, C, Maracci, C, Holtkamp, W, Wilson, D.N, Fischer, N, Rodnina, M.V.
Deposit date:2020-04-23
Release date:2020-08-19
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Mechanism of ribosome rescue by alternative ribosome-rescue factor B.
Nat Commun, 11, 2020
3DEG
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BU of 3deg by Molmil
Complex of elongating Escherichia coli 70S ribosome and EF4(LepA)-GMPPNP
Descriptor: 30S RNA helix 14, 30S RNA helix 8, 30S ribosomal protein S12, ...
Authors:Connell, S.R, Topf, M, Qin, Y, Wilson, D.N, Mielke, T, Fucini, P, Nierhaus, K.H, Spahn, C.M.T.
Deposit date:2008-06-10
Release date:2008-08-19
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (10.9 Å)
Cite:A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation
Nat.Struct.Mol.Biol., 15, 2008
4INW
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BU of 4inw by Molmil
Structure of Pheromone-binding protein 1 in complex with (11Z,13Z)-hexadecadienal
Descriptor: (11Z,13Z)-hexadeca-11,13-dienal, Pheromone-binding protein 1
Authors:di Luccio, E, Wilson, D.K.
Deposit date:2013-01-07
Release date:2013-03-06
Method:X-RAY DIFFRACTION (1.14 Å)
Cite:Crystallographic Observation of pH-Induced Conformational Changes in the Amyelois transitella Pheromone-Binding Protein AtraPBP1.
Plos One, 8, 2013
5UJG
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BU of 5ujg by Molmil
ovGRN12-35_3s
Descriptor: Granulin
Authors:Bansal, P, Smout, M, Wilson, D, Caceres, C.C, Dastpeyman, M, Sotillo, J, Seifert, J, Brindley, P, Loukas, A, Daly, N.
Deposit date:2017-01-17
Release date:2018-01-24
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Development of a Potent Wound Healing Agent Based on the Liver Fluke Granulin Structural Fold.
J. Med. Chem., 60, 2017
4UE4
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BU of 4ue4 by Molmil
Structural basis for targeting and elongation arrest of Bacillus signal recognition particle
Descriptor: 6S RNA, FTSQ SIGNAL SEQUENCE, SIGNAL RECOGNITION PARTICLE PROTEIN
Authors:Beckert, B, Kedrov, A, Sohmen, D, Kempf, G, Wild, K, Sinning, I, Stahlberg, H, Wilson, D.N, Beckmann, R.
Deposit date:2014-12-15
Release date:2015-09-09
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Translational Arrest by a Prokaryotic Signal Recognition Particle is Mediated by RNA Interactions.
Nat.Struct.Mol.Biol., 22, 2015
7KWK
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BU of 7kwk by Molmil
DNA-DB1879 complex: The DNA sequence 5'-CGCGAATTCGCG-3' presents a binding site for the heterocyclic small molecule (DB1879).
Descriptor: 2-[5-(4-carbamimidoylphenyl)thiophen-2-yl]-1H-indole-6-carboximidamide, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION
Authors:Ogbonna, E, Fang, Z, Wilson, D.W.
Deposit date:2020-12-01
Release date:2021-12-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Drug design and DNA structural research inspired by the Neidle laboratory: DNA minor groove binding and transcription factor inhibition by thiophene diamidines.
Bioorg.Med.Chem., 68, 2022
6H58
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BU of 6h58 by Molmil
Structure of a hibernating 100S ribosome reveals an inactive conformation of the ribosomal protein S1 - Full 100S Hibernating E. coli Ribosome
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S1, ...
Authors:Beckert, B, Turk, M, Czech, A, Berninghausen, O, Beckmann, R, Ignatova, Z, Plitzko, J, Wilson, D.N.
Deposit date:2018-07-24
Release date:2018-09-05
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (7.9 Å)
Cite:Structure of a hibernating 100S ribosome reveals an inactive conformation of the ribosomal protein S1.
Nat Microbiol, 3, 2018
5UJH
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BU of 5ujh by Molmil
ov-GRN12-34
Descriptor: Granulin
Authors:Bansal, P, Smout, M, Wilson, D, Caceres, C.C, Dastpeyman, M, Sotillo, J, Seifert, J, Brindley, P, Loukas, A, Daly, N.
Deposit date:2017-01-18
Release date:2018-01-24
Last modified:2024-10-23
Method:SOLUTION NMR
Cite:Development of a Potent Wound Healing Agent Based on the Liver Fluke Granulin Structural Fold.
J. Med. Chem., 60, 2017
4V6W
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BU of 4v6w by Molmil
Structure of the D. melanogaster 80S ribosome
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 2S ribosomal RNA, ...
Authors:Anger, A.M, Armache, J.-P, Berninghausen, O, Habeck, M, Subklewe, M, Wilson, D.N, Beckmann, R.
Deposit date:2013-02-27
Release date:2014-07-09
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Structures of the human and Drosophila 80S ribosome.
Nature, 497, 2013
5MLC
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BU of 5mlc by Molmil
Cryo-EM structure of the spinach chloroplast ribosome reveals the location of plastid-specific ribosomal proteins and extensions
Descriptor: 23S ribosomal RNA, chloroplastic, 4.8S ribosomal RNA, ...
Authors:Graf, M, Arenz, S, Huter, P, Doenhoefer, A, Novacek, J, Wilson, D.N.
Deposit date:2016-12-06
Release date:2016-12-28
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of the spinach chloroplast ribosome reveals the location of plastid-specific ribosomal proteins and extensions.
Nucleic Acids Res., 45, 2017
3J25
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BU of 3j25 by Molmil
Structural basis for TetM-mediated tetracycline resistance
Descriptor: PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Tetracycline resistance protein tetM
Authors:Doenhoefer, A, Franckenberg, S, Wickles, S, Berninghausen, O, Beckmann, R, Wilson, D.N.
Deposit date:2012-08-22
Release date:2012-10-17
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (7.2 Å)
Cite:Structural basis for TetM-mediated tetracycline resistance.
Proc.Natl.Acad.Sci.USA, 109, 2012
4UE5
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BU of 4ue5 by Molmil
Structural basis for targeting and elongation arrest of Bacillus signal recognition particle
Descriptor: 7S RNA, SIGNAL RECOGNITION PARTICLE 54 KDA PROTEIN, SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN, ...
Authors:Beckert, B, Kedrov, A, Sohmen, D, Kempf, G, Wild, K, Sinning, I, Stahlberg, H, Wilson, D.N, Beckmann, R.
Deposit date:2014-12-15
Release date:2015-09-09
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Translational Arrest by a Prokaryotic Signal Recognition Particle is Mediated by RNA Interactions.
Nat.Struct.Mol.Biol., 22, 2015
6FKR
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BU of 6fkr by Molmil
Crystal structure of the dolphin proline-rich antimicrobial peptide Tur1A bound to the Thermus thermophilus 70S ribosome
Descriptor: 16 ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Mardirossian, M, Perebaskine, N, Benincasa, M, Gambato, S, Hofmann, S, Huter, P, Muller, C, Hilpert, K, Innis, C.A, Tossi, A, Wilson, D.N.
Deposit date:2018-01-24
Release date:2018-03-28
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The Dolphin Proline-Rich Antimicrobial Peptide Tur1A Inhibits Protein Synthesis by Targeting the Bacterial Ribosome.
Cell Chem Biol, 25, 2018
7NSQ
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BU of 7nsq by Molmil
Structure of ErmDL-Telithromycin-stalled 70S E. coli ribosomal complex with A and P-tRNA
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Beckert, B, Wilson, D.N.
Deposit date:2021-03-08
Release date:2021-07-14
Last modified:2021-08-11
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics.
Nat Commun, 12, 2021
5O2R
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BU of 5o2r by Molmil
Cryo-EM structure of the proline-rich antimicrobial peptide Api137 bound to the terminating ribosome
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Graf, M, Berninghausen, O, Beckmann, R, Wilson, D.N.
Deposit date:2017-05-22
Release date:2017-07-26
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome.
Nat. Struct. Mol. Biol., 24, 2017
4ZER
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BU of 4zer by Molmil
Crystal structure of the Onc112 antimicrobial peptide bound to the Thermus thermophilus 70S ribosome
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 16s ribosomal RNA, 23s ribosomal RNA, ...
Authors:Seefeldt, A.C, Nguyen, F, Antunes, S, Perebaskine, N, Graf, M, Arenz, S, Inampudi, K.K, Douat, C, Guichard, G, Wilson, D.N, Innis, C.A.
Deposit date:2015-04-20
Release date:2015-05-20
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The proline-rich antimicrobial peptide Onc112 inhibits translation by blocking and destabilizing the initiation complex.
Nat.Struct.Mol.Biol., 22, 2015
6D9F
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BU of 6d9f by Molmil
Protein 60 with aldehyde deformylating oxidase activity from Kitasatospora setae
Descriptor: 1,2-ETHANEDIOL, FE (III) ION, Putative VlmB homolog, ...
Authors:Arenas, R, Wilson, D.K, Mak, W.S, Siegel, J.B.
Deposit date:2018-04-28
Release date:2019-05-08
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Discovery, Design, and Structural Characterization of Alkane-Producing Enzymes across the Ferritin-like Superfamily.
Biochemistry, 59, 2020

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