5LO4
 
 | | Engineering protein stability with atomic precision in a monomeric miniprotein | | Descriptor: | PPa-CH3 | | Authors: | Baker, E.G, Williams, C, Hudson, K.L, Bartlett, G.G, Heal, J.W, Sessions, R.B, Crump, M.P, Woolfson, D.N. | | Deposit date: | 2016-08-08 | | Release date: | 2017-05-17 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Engineering protein stability with atomic precision in a monomeric miniprotein.
Nat. Chem. Biol., 13, 2017
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5LO2
 | | Engineering protein stability with atomic precision in a monomeric miniprotein | | Descriptor: | PPaTyr | | Authors: | Baker, E.G, Hudson, K.L, Williams, C, Bartlett, G.G, Heal, J.W, Sessions, R.B, Crump, M.P, Woolfson, D.N. | | Deposit date: | 2016-08-08 | | Release date: | 2017-05-17 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Engineering protein stability with atomic precision in a monomeric miniprotein.
Nat. Chem. Biol., 13, 2017
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5LO3
 | | Engineering protein stability with atomic precision in a monomeric miniprotein | | Descriptor: | PPaOMe | | Authors: | Baker, E.G, Hudson, K.L, Williams, C, Bartlett, G.G, Heal, J.W, Sessions, R.B, Crump, M.P, Woolfson, D.N. | | Deposit date: | 2016-08-08 | | Release date: | 2017-05-17 | | Last modified: | 2023-11-15 | | Method: | SOLUTION NMR | | Cite: | Engineering protein stability with atomic precision in a monomeric miniprotein.
Nat. Chem. Biol., 13, 2017
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5NKZ
 | | Crystal structure of H. polymorpha ubiquitin conjugating enzyme Pex4p in complex with soluble domain of Pex22p | | Descriptor: | Peroxin 22, Ubiquitin-conjugating enzyme E2-21 kDa | | Authors: | Danda, N, Lunev, S, Ali, A, Groves, M.R, Williams, C. | | Deposit date: | 2017-04-03 | | Release date: | 2018-01-24 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Structural insights into K48-linked ubiquitin chain formation by the Pex4p-Pex22p complex.
Biochem. Biophys. Res. Commun., 496, 2018
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4I8A
 | | Alanine-glyoxylate aminotransferase variant S187F | | Descriptor: | GLYCEROL, Serine-pyruvate aminotransferase | | Authors: | Fodor, K, Oppici, E, Williams, C, Cellini, B, Wilmanns, M. | | Deposit date: | 2012-12-03 | | Release date: | 2013-05-01 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal structure of the S187F variant of human liver alanine: Aminotransferase associated with primary hyperoxaluria type I and its functional implications.
Proteins, 81, 2013
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3DET
 | | Structure of the E148A, Y445A doubly ungated mutant of E.coli CLC_Ec1, Cl-/H+ antiporter | | Descriptor: | Fab fragment, Heavy chain, Light chain, ... | | Authors: | Jayaram, H, Accardi, A, Wu, F, Williams, C, Miller, C. | | Deposit date: | 2008-06-10 | | Release date: | 2008-06-17 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Ion permeation through a Cl--selective channel designed from a CLC Cl-/H+ exchanger
Proc.Natl.Acad.Sci.USA, 105, 2008
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8OL8
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8OJR
 | | Solution NMR Structure of Alpha-Synuclein 1-25 Peptide in 50% TFE. | | Descriptor: | Alpha-synuclein | | Authors: | Allen, S.G, Williams, C, Meade, R.M, Tang, T.M.S, Crump, M.P, Mason, J.M. | | Deposit date: | 2023-03-24 | | Release date: | 2023-08-09 | | Method: | SOLUTION NMR | | Cite: | An N-terminal alpha-Synuclein fragment binds lipid vesicles to modulate lipid induced aggregation
Cell Rep Phys Sci, 2023
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5NL8
 | | Pex4 of Hansenula Polymorpha | | Descriptor: | Ubiquitin-conjugating enzyme E2-21 kDa | | Authors: | Groves, M, Williams, C. | | Deposit date: | 2017-04-04 | | Release date: | 2018-01-24 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural insights into K48-linked ubiquitin chain formation by the Pex4p-Pex22p complex.
Biochem. Biophys. Res. Commun., 496, 2018
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2CNR
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2B4K
 | | Acetobacter turbidans alpha-amino acid ester hydrolase complexed with phenylglycine | | Descriptor: | Alpha-amino acid ester hydrolase, D-PHENYLGLYCINE, GLYCEROL | | Authors: | Barends, T.R.M, Polderman-Tijmes, J.J, Jekel, P.A, Williams, C, Wybenga, G, Janssen, D.B, Dijkstra, B.W. | | Deposit date: | 2005-09-26 | | Release date: | 2005-12-27 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Acetobacter turbidans alpha-amino acid ester hydrolase: how a single mutation improves an antibiotic-producing enzyme.
J.Biol.Chem., 281, 2006
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6GWX
 | | Stabilising and Understanding a Miniprotein by Rational Design. | | Descriptor: | Optimised PPa-TYR | | Authors: | Porter Goff, K.L, Williams, C, Baker, E.G, Nicol, D, Samphire, J.L, Zieleniewski, F.L, Crump, M.P, Woolfson, D.N. | | Deposit date: | 2018-06-26 | | Release date: | 2019-07-10 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Stabilizing and Understanding a Miniprotein by Rational Redesign.
Biochemistry, 58, 2019
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2HT2
 | | Structure of the Escherichia coli ClC chloride channel Y445H mutant and Fab complex | | Descriptor: | BROMIDE ION, Fab fragment, heavy chain, ... | | Authors: | Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. | | Deposit date: | 2006-07-25 | | Release date: | 2006-09-19 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (3.32 Å) | | Cite: | Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger.
J.Mol.Biol., 362, 2006
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2HLF
 | | Structure of the Escherichis coli ClC chloride channel Y445E mutant and Fab complex | | Descriptor: | BROMIDE ION, Fab Fragment, Heavy chain, ... | | Authors: | Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. | | Deposit date: | 2006-07-07 | | Release date: | 2006-09-19 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger
J.Mol.Biol., 362, 2006
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2HTL
 | | Structure of the Escherichia coli ClC chloride channel Y445F mutant and Fab complex | | Descriptor: | BROMIDE ION, Fab fragment, Heavy chain, ... | | Authors: | Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. | | Deposit date: | 2006-07-26 | | Release date: | 2006-09-19 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger.
J.Mol.Biol., 362, 2006
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2HTK
 | | Structure of the Escherichia coli ClC chloride channel Y445A mutant and Fab complex | | Descriptor: | BROMIDE ION, Fab fragment, Heavy chain, ... | | Authors: | Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. | | Deposit date: | 2006-07-26 | | Release date: | 2006-09-19 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3.41 Å) | | Cite: | Synergism between halide binding and proton transport in a CLC-type exchanger
J.Mol.Biol., 362, 2006
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2HT3
 | | Structure of the Escherichia coli ClC chloride channel Y445L mutant and Fab complex | | Descriptor: | BROMIDE ION, Fab fragment, Heavy chain, ... | | Authors: | Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. | | Deposit date: | 2006-07-25 | | Release date: | 2006-09-19 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Synergism between halide binding and proton transport in a CLC-type exchanger
J.Mol.Biol., 362, 2006
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2HT4
 | | Structure of the Escherichia coli ClC chloride channel Y445W mutant and Fab complex | | Descriptor: | BROMIDE ION, Fab fragment, Heavy chain, ... | | Authors: | Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. | | Deposit date: | 2006-07-25 | | Release date: | 2006-09-19 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger.
J.Mol.Biol., 362, 2006
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2LLA
 | | NMR solution structure ensemble of domain 11 of the echidna M6P/IGF2R receptor | | Descriptor: | Mannose-6-phosphate/insulin-like growth factor II receptor | | Authors: | Strickland, M, Crump, M.P, Williams, C, Rezgui, D, Ellis, R.Z, Hoppe, H, Frago, S, Prince, S.N, Zaccheo, O.J, Forbes, B.E, Jones, E, Hassan, A.Z, Wattana-Amorn, P. | | Deposit date: | 2011-11-05 | | Release date: | 2012-11-07 | | Last modified: | 2012-12-12 | | Method: | SOLUTION NMR | | Cite: | An exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution.
Science, 338, 2012
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2LP8
 | | SOLUTION STRUCTURE OF AN APOPTOSIS ACTIVATING PHOTOSWITCHABLE BAK PEPTIDE BOUND to BCL-XL | | Descriptor: | 3,3'-(E)-diazene-1,2-diylbis{6-[(chloroacetyl)amino]benzenesulfonic acid}, Bcl-2 homologous antagonist/killer, Bcl-2-like protein 1 | | Authors: | Wysoczanski, P, Mart, R.J, Loveridge, J.E, Williams, C, Whittaker, S.B.-M, Crump, M.P, Allemann, R.K. | | Deposit date: | 2012-02-03 | | Release date: | 2012-04-18 | | Last modified: | 2021-08-18 | | Method: | SOLUTION NMR | | Cite: | NMR Solution Structure of a Photoswitchable Apoptosis Activating Bak Peptide Bound to Bcl-x(L).
J.Am.Chem.Soc., 134, 2012
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2LPC
 | | NMR STRUCTURE of Bcl-XL | | Descriptor: | Bcl-2-like protein 1 | | Authors: | Wysoczanski, P, Mart, R.J, Loveridge, J.E, Williams, C, Whittaker, S.B.-M, Crump, M.P, Allemann, R.K. | | Deposit date: | 2012-02-09 | | Release date: | 2012-03-21 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | NMR Solution Structure of a Photoswitchable Apoptosis Activating Bak Peptide Bound to Bcl-x(L).
J.Am.Chem.Soc., 134, 2012
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2M6T
 | | NMR solution structure ensemble of 3-4D mutant domain 11 IGF2R | | Descriptor: | Insulin-like growth factor 2 receptor variant | | Authors: | Strickland, M, Williams, C, Richards, E, Minnall, L, Crump, M.P, Frago, S, Hughes, J, Garner, L, Hoppe, H, Rezgui, D, Zaccheo, O.J, Prince, S.N, Hassan, A.B, Whittaker, S. | | Deposit date: | 2013-04-09 | | Release date: | 2014-10-15 | | Last modified: | 2016-06-01 | | Method: | SOLUTION NMR | | Cite: | Functional evolution of IGF2:IGF2R domain 11 binding generates novel structural interactions and a specific IGF2 antagonist.
Proc.Natl.Acad.Sci.USA, 113, 2016
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2M68
 | | NMR solution structure ensemble of 3-4D mutant domain 11 IGF2R in complex with IGF2 (domain 11 structure only) | | Descriptor: | Insulin-like growth factor 2 receptor variant | | Authors: | Strickland, M, Williams, C, Richards, E, Minnall, L, Crump, M.P, Frago, S, Hughes, J, Garner, L, Hoppe, H, Rezgui, D, Zaccheo, O.J, Prince, S.N, Hassan, A.B, Whittaker, S. | | Deposit date: | 2013-03-27 | | Release date: | 2014-10-15 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Functional evolution of IGF2:IGF2R domain 11 binding generates novel structural interactions and a specific IGF2 antagonist.
Proc.Natl.Acad.Sci.USA, 113, 2016
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2PNG
 | | Type I rat fatty acid synthase acyl carrier protein (ACP) domain | | Descriptor: | Fatty acid synthase (EC 2.3.1.85) | | Authors: | Ploskon, E.A, Arthur, C.J, Evans, S.E, Williams, C, Crosby, J, Crump, M.P. | | Deposit date: | 2007-04-24 | | Release date: | 2007-06-05 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | A Mammalian type I Fatty Acid synthase acyl carrier protein domain does not sequester acyl chains.
J.Biol.Chem., 283, 2008
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6G1N
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